Ludmilla A Shuvalova

  • 638 Citations
1986 …2020

Research output per year

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Research Output

  • 638 Citations
  • 41 Article
  • 2 Comment/debate
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Article
2020

Structure of galactarate dehydratase, a new fold in an enolase involved in bacterial fitness after antibiotic treatment

Rosas-Lemus, M., Minasov, G., Shuvalova, L., Wawrzak, Z., Kiryukhina, O., Mih, N., Jaroszewski, L., Palsson, B., Godzik, A. & Satchell, K. J. F., Mar 1 2020, In : Protein Science. 29, 3, p. 711-722 12 p.

Research output: Contribution to journalArticle

2019

Pyrimidine biosynthesis in pathogens – Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae

Lipowska, J., Miks, C. D., Kwon, K., Shuvalova, L. A., Zheng, H., Lewiński, K., Cooper, D. R., Shabalin, I. G. & Minor, W., Sep 1 2019, In : International Journal of Biological Macromolecules. 136, p. 1176-1187 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii

Lykins, J. D., Filippova, E. V., Halavaty, A. S., Minasov, G., Zhou, Y., Dubrovska, I., Flores, K. J., Shuvalova, L. A., Ruan, J., El Bissati, K., Dovgin, S., Roberts, C. W., Woods, S., Moulton, J. D., Moulton, H., McPhillie, M. J., Muench, S. P., Fishwick, C. W. G., Sabini, E., Shanmugam, D. & 4 others, Roos, D. S., McLeod, R., Anderson, W. F. & Ngô, H. M., Jan 1 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

Structural and immunological characterization of E. coli derived recombinant CRM197 protein used as carrier in conjugate vaccines

Mishra, R. P. N., Yadav, R. S. P., Jones, C., Nocadello, S., Minasov, G., Shuvalova, L. A., Anderson, W. F. & Goel, A., Sep 25 2018, In : Bioscience Reports. 38, 5, BSR20180238.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Crystal structures of the components of the Staphylococcus aureus leukotoxin ED

Nocadello, S., Minasov, G., Shuvalova, L., Dubrovska, I., Sabini, E., Bagnoli, F., Grandi, G. & Anderson, W. F., Jan 1 2016, In : Acta Crystallographica Section D: Structural Biology. 72, 1, p. 113-120 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Crystal structures of the spoiid lytic transglycosylases essential for bacterial sporulation

Nocadello, S., Minasov, G., Shuvalova, L. S., Dubrovska, I., Sabini, E. & Anderson, W. F., Jul 15 2016, In : Journal of Biological Chemistry. 291, 29, p. 14915-14926 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis

Kuhn, M. L., Alexander, E., Minasov, G., Page, H. J., Warwrzak, Z., Shuvalova, L., Flores, K. J., Wilson, D. J., Shi, C., Aldrich, C. C. & Anderson, W. F., Aug 12 2016, In : ACS Infectious Diseases. 2, 8, p. 579-591 13 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus

Halavaty, A. S., Rich, R. L., Chen, C., Joo, J. C., Minasov, G., Dubrovska, I., Winsor, J. R., Myszka, D. G., Duban, M., Shuvalova, L., Yakunin, A. F. & Anderson, W. F., May 1 2015, In : Acta Crystallographica Section D: Biological Crystallography. 71, p. 1159-1175 17 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Mechanisms of allosteric activation and inhibition of the deoxyribonucleoside triphosphate triphosphohydrolase from Enterococcus faecalis

Vorontsov, I. I., Wu, Y., Delucia, M., Minasov, G., Mehrens, J., Shuvalova, L., Anderson, W. F. & Ahn, J., Jan 31 2014, In : Journal of Biological Chemistry. 289, 5, p. 2815-2824 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Parallel protein purification

Shuvalova, L., Jan 1 2014, In : Methods in Molecular Biology. 1140, p. 137-143 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
3 Scopus citations

Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP

Kuhn, M. L., Prachi, P., Minasov, G., Shuvalova, L., Ruan, J., Dubrovska, I., Winsor, J., Giraldi, M., Biagini, M., Liberatori, S., Savino, S., Bagnoli, F., Anderson, W. F. & Grandi, G., Apr 2014, In : FASEB Journal. 28, 4, p. 1780-1793 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2013

Characterization of fibrinogen binding by glycoproteins Srr1 and Srr2 of Streptococcus agalactiae

Seo, H. S., Minasov, G., Seepersaud, R., Doran, K. S., Dubrovska, I., Shuvalova, L., Anderson, W. F., Iverson, T. M. & Sullam, P. M., Dec 13 2013, In : Journal of Biological Chemistry. 288, 50, p. 35982-35996 15 p.

Research output: Contribution to journalArticle

45 Scopus citations

Large scale structural rearrangement of a serine hydrolase from francisella tularensis facilitates catalysis

Filippova, E. V., Weston, L. A., Kuhn, M. L., Geissler, B., Gehring, A. M., Armoush, N., Adkins, C. T., Minasov, G., Dubrovska, I., Shuvalova, L., Winsor, J. R., Lavis, L. D., Satchell, K. J. F., Becker, D. P., Anderson, W. F. & Johnson, R. J., Apr 12 2013, In : Journal of Biological Chemistry. 288, 15, p. 10522-10535 14 p.

Research output: Contribution to journalArticle

19 Scopus citations
2012

Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain

Light, S. H., Halavaty, A. S., Minasov, G., Shuvalova, L. & Anderson, W. F., Jun 1 2012, In : Protein Science. 21, 6, p. 887-895 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria

Halavaty, A. S., Kim, Y., Minasov, G., Shuvalova, L., Dubrovska, I., Winsor, J., Zhou, M., Onopriyenko, O., Skarina, T., Papazisi, L., Kwon, K., Peterson, S. N., Joachimiak, A., Savchenko, A. & Anderson, W. F., Oct 1 2012, In : Acta Crystallographica Section D: Biological Crystallography. 68, 10, p. 1359-1370 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Structure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcU

Halavaty, A. S., Borek, D., Tyson, G. H., Veesenmeyer, J. L., Shuvalova, L., Minasov, G., Otwinowski, Z., Hauser, A. R. & Anderson, W. F., Nov 14 2012, In : PloS one. 7, 11, e49388.

Research output: Contribution to journalArticle

25 Scopus citations
2011

A conserved surface loop in type i dehydroquinate dehydratases positions an active site arginine and functions in substrate binding

Light, S. H., Minasov, G., Shuvalova, L. A., Peterson, S. N., Caffrey, M., Anderson, W. F. & Lavie, A., Mar 29 2011, In : Biochemistry. 50, 12, p. 2357-2363 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
27 Scopus citations
8 Scopus citations

Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates

Light, S. H., Minasov, G., Shuvalova, L. A., Duban, M. E., Caffrey, M., Anderson, W. F. & Lavie, A., Feb 4 2011, In : Journal of Biological Chemistry. 286, 5, p. 3531-3539 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2009

Crystal structures of Ykul and its complex with second messenger cyclic Di-GMP suggest catalytic mechanism of phosphodiester bond cleavage by EAL domains

Minasov, G., Padavattan, S., Shuvalova, L., Brunzelle, J. S., Miller, D. J., Baslé, A., Massa, C., Collart, F. R., Schirmer, T. & Anderson, W. F., May 8 2009, In : Journal of Biological Chemistry. 284, 19, p. 13174-13184 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Structural and molecular mechanism for autoprocessing of MARTX toxin of vibrio cholerae at multiple sites

Prochazkova, K., Shuvalova, L. A., Minasov, G., Voburka, Z., Anderson, W. F. & Satchell, K. J. F., Sep 25 2009, In : Journal of Biological Chemistry. 284, 39, p. 26557-26568 12 p.

Research output: Contribution to journalArticle

52 Scopus citations
2007

Crystal structure of an apo form of Shigella flexneri ArsH protein with an NADPH-dependent FMN reductase activity

Vorontsov, I. I., Minasov, G., Brunzelle, J. S., Shuvalova, L., Kiryukhina, O., Collart, F. R. & Anderson, W. F., Nov 1 2007, In : Protein Science. 16, 11, p. 2483-2490 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Structural and biochemical characterization of a novel Mn 2+-dependent phosphodiesterase encoded by the yfcE gene

Miller, D. J., Shuvalova, L., Evdokimova, E., Savchenko, A., Yakunin, A. F. & Anderson, W. F., Jul 1 2007, In : Protein Science. 16, 7, p. 1338-1348 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

The 2.2 Å resolution crystal structure of Bacillus cereus Nif3-family protein YqfO reveals a conserved dimetal-binding motif and a regulatory domain

Godsey, M. H., Minasov, G., Shuvalova, L., Brunzelle, J. S., Vorontsov, I. I., Collart, F. R. & Anderson, W. F., Jul 1 2007, In : Protein Science. 16, 7, p. 1285-1293 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
2006

Crystal structure of YfiR, an unusual TetR/CamR-type putative transcriptional regulator from Bacillus subtilis

Rajan, S. S., Yang, X., Shuvalova, L., Collart, F. & Anderson, W. F., Oct 1 2006, In : Proteins: Structure, Function and Genetics. 65, 1, p. 255-257 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
2004

YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology

Rajan, S. S., Yang, X., Shuvalova, L. A., Collart, F. & Anderson, W. F., Dec 14 2004, In : Biochemistry. 43, 49, p. 15472-15479 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
2003

Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases

Gardberg, A., Shuvalova, L., Monnerjahn, C., Konrad, M. & Lavie, A., Oct 1 2003, In : Structure. 11, 10, p. 1265-1277 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Structure of the Bacillus subtilis YYCN Protein: A Putative N-Acetyltransferase

Taneja, B., Maar, S., Shuvalova, L., Collart, F., Anderson, W. & Mondragón, A., Dec 1 2003, In : Proteins: Structure, Function and Genetics. 53, 4, p. 950-952 3 p.

Research output: Contribution to journalArticle

2002

Structural characterization of the closed conformation of mouse guanylate kinase.

Sekulic, N., Shuvalova, L., Spangenberg, O., Konrad, M. & Lavie, A., Aug 16 2002, In : The Journal of biological chemistry. 277, 33, p. 30236-30243 8 p.

Research output: Contribution to journalArticle

55 Scopus citations
1999
29 Scopus citations
1992

A hypothalamic activator of calmodulin-dependent enzymes is thymosin β4 (1-39)

Galoyan, A. A., Gurvits, B. Y., Shuvalova, L. A., Davis, M. T., Shively, J. E. & Lee, T. D., Aug 1 1992, In : Neurochemical Research. 17, 8, p. 773-777 5 p.

Research output: Contribution to journalArticle

13 Scopus citations
1991

Vliianie slabogo magnitnogo polia v rezhime parametricheskogo rezonansa na skorost' kal'modulinzavisimogo fosforilirovaniia miozina v rastvore.

Translated title of the contribution: The effect of a weak magnetic field in the paramagnetic resonance mode on the rate of the calmodulin-dependent phosphorylation of myosin in solutionShuvalova, L. A., Ostrovskaia, M. V., Sosunov, E. A. & Lednev, V. V., Jan 1 1991, In : Doklady Akademii nauk SSSR. 317, 1, p. 227-230 4 p.

Research output: Contribution to journalArticle

39 Scopus citations
1987

Izmenenie strukturnogo sostoianiia miozinovykh niteǐ v glitserinizirovannykh voloknakh skeletnykh myshts krolika, indutsiruemye fosforilirovaniem legkikh tsepeǐ miozina.

Translated title of the contribution: Changes in the structural state of myosin filaments in glycerol-treated fibers of rabbit skeletal muscles induced by phosphorylation of myosin light chainsBorovikov, I. S., Levitskiǐ, D. I., Shuvalova, L. A., Lebedeva, N. N. & Poglazov, B. F., Dec 1 1987, In : Biokhimiya. 52, 12, p. 2061-2065 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Ordered assemblies of myosin minifilaments

Podlubnaya, Z. A., Levitsky, D. I., Shuvalova, L. A. & Poglazov, B. F., Aug 5 1987, In : Journal of Molecular Biology. 196, 3, p. 729-732 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Poluchenie glitserinizirovannykh modeleǐ myshechnykh volokon s fosforilirovannymi legkimi tsepiami miozina.

Translated title of the contribution: Production of glycerinated models of muscle fibers with phosphorylated myosin light chainsLebedeva, N. N., Wrotek, M., Shuvalova, L. A., Konkol, I. & Borovikov, I. S., Aug 1 1987, In : Tsitologiya. 29, 8, p. 973-975 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

The effect of myosin light chain phosphorylation on the actin-stimulated ATPase activity of myosin minifilaments

Levitsky, D. I., Shuvalova, L. A. & Poglazov, B. F., Aug 31 1987, In : FEBS Letters. 221, 1, p. 77-80 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Vliianie fosforilirovaniia legkikh tsepeǐ miozina na vzaimodeǐstvie miozinovykh minifilamentov s F-aktinom.

Translated title of the contribution: Effect of phosphorylation of myosin light chains on the interaction of myosin minifilaments with F-actinLevitskiǐ, D. I., Shuvalova, L. A., Kalmykov, P. V. & Poglazov, B. F., May 1 1987, In : Biokhimiya. 52, 5, p. 813-824 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
1986

Uporiadochennaia samosborka miozinovykh minifilamentov: vliianie Mg2+ i fosforilirovaniia legkikh tsepeǐ miozina.

Translated title of the contribution: Regulated self-assembly of myosin minifilaments: the effect of Mg2+ and phosphorylation of myosin light chainsPodlubnaia, Z. A., Levitskiǐ, D. I., Shuvalova, L. A. & Poglazov, B. F., Dec 1 1986, In : Doklady Akademii nauk SSSR. 290, 4, p. 1015-1017 3 p.

Research output: Contribution to journalArticle

2 Scopus citations