Lynn Peterson Lowe

  • 5622 Citations
19942019
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Research Output 1994 2019

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Article
2019

Cord Blood Metabolomics: Association With Newborn Anthropometrics and C-Peptide Across Ancestries

HAPO Study Cooperative Research Group, Oct 1 2019, In : The Journal of clinical endocrinology and metabolism. 104, 10, p. 4459-4472 14 p.

Research output: Contribution to journalArticle

Metabolomics
C-Peptide
Fetal Blood
Blood
Metabolites
10 Citations (Scopus)

Hyperglycemia and adverse Pregnancy Outcome follow-up study (HAPO FUS): Maternal gestational diabetes mellitus and childhood glucose metabolism

on behalf of the HAPO Follow-up Study Cooperative Research Group*, Mar 1 2019, In : Diabetes care. 42, 3, p. 372-380 9 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Pregnancy Outcome
Hyperglycemia
Mothers
Glucose
15 Citations (Scopus)

Hyperglycemia and adverse Pregnancy Outcome follow-up study (HAPO FUS): Maternal glycemia and childhood glucose metabolism

the HAPO Follow-up Study Cooperative Research Group, Mar 1 2019, In : Diabetes care. 42, 3, p. 381-392 12 p.

Research output: Contribution to journalArticle

Pregnancy Outcome
Hyperglycemia
Mothers
Glucose
Fasting
7 Citations (Scopus)

Maternal glucose levels during pregnancy and childhood adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study

on behalf of the HAPO Follow-up Study Cooperative Research Group, Apr 1 2019, In : Diabetologia. 62, 4, p. 598-610 13 p.

Research output: Contribution to journalArticle

Adiposity
Pregnancy Outcome
Hyperglycemia
Mothers
Glucose
1 Citation (Scopus)

Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries

for the HAPO Study Cooperative Research Group, Mar 1 2019, In : Diabetologia. 62, 3, p. 473-484 12 p.

Research output: Contribution to journalArticle

Hyperinsulinism
Mothers
Newborn Infant
Pregnancy
C-Peptide
2018
34 Citations (Scopus)

Association of gestational diabetes with maternal disorders of glucose metabolism and childhood adiposity

HAPO Follow-up Study Cooperative Research, Sep 11 2018, In : JAMA - Journal of the American Medical Association. 320, 10, p. 1005-1016 12 p.

Research output: Contribution to journalArticle

Glucose Metabolism Disorders
Gestational Diabetes
Adiposity
Mothers
Odds Ratio
2017
25 Citations (Scopus)

Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes

Sandler, V., Reisetter, A. C., Bain, J. R., Muehlbauer, M. J., Nodzenski, M., Stevens, R. D., Ilkayeva, O., Lowe, L. P., Metzger, B. E., Newgard, C. B., Scholtens, D. M., Lowe, W. L. & for the HAPO Study Cooperative Research Group, T. HAPO. S. C. R. G., Mar 1 2017, In : Diabetologia. 60, 3, p. 518-530 13 p.

Research output: Contribution to journalArticle

Metabolome
Insulin Resistance
Mothers
Lipids
Adiposity
3 Citations (Scopus)

Genetic determinants of adiponectin regulation revealed by pregnancy

Hivert, M. F., Scholtens, D. M., Allard, C., Nodzenski, M., Bouchard, L., Brisson, D., Lowe, L. P., McDowell, I., Reddy, T., Dastani, Z., Richards, J. B., Hayes, M. G. & Lowe, W. L., May 2017, In : Obesity. 25, 5, p. 935-944 10 p.

Research output: Contribution to journalArticle

Adiponectin
Alleles
Pregnancy
Adipocytes
Leptin
18 Citations (Scopus)

Maternal BMI and glycemia impact the fetal metabolome

for the HAPO Study Cooperative Research Group, Jul 1 2017, In : Diabetes care. 40, 7, p. 902-910 9 p.

Research output: Contribution to journalArticle

Metabolome
Fetal Blood
Mothers
Newborn Infant
Metabolomics
11 Citations (Scopus)

Targeted metabolomics demonstrates distinct and overlapping maternal metabolites associated with BMI, glucose, and insulin sensitivity during pregnancy across four ancestry groups

for the HAPO Study Cooperative Research Group, Jul 1 2017, In : Diabetes care. 40, 7, p. 911-919 9 p.

Research output: Contribution to journalArticle

Metabolomics
Insulin Resistance
Mothers
Phenotype
Glucose
2016
28 Citations (Scopus)

Maternal and neonatal morbidity for women who would be added to the diagnosis of GDM using IADPSG criteria: A secondary analysis of the hyperglycemia and adverse pregnancy outcome study

Waters, T. P., Dyer, A. R., Scholtens, D. M., Dooley, S. L., Herer, E., Lowe, L. P., Oats, J. J. N., Persson, B., Sacks, D. A., Metzger, B. E. & Catalano, P. M., Jan 1 2016, In : Diabetes care. 39, 12, p. 2204-2210 7 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Pregnancy Outcome
Hyperglycemia
Mothers
Outcome Assessment (Health Care)
22 Citations (Scopus)

Metabolic networks and metabolites underlie associations between maternal glucose during pregnancy and newborn size at birth

Scholtens, D. M., Bain, J. R., Reisetter, A. C., Muehlbauer, M. J., Nodzenski, M., Stevens, R. D., Ilkayeva, O., Lowe, L. P., Metzger, B. E., Newgard, C. B. & Lowe, W. L., Jul 1 2016, In : Diabetes. 65, 7, p. 2039-2050 12 p.

Research output: Contribution to journalArticle

Metabolic Networks and Pathways
Mothers
Parturition
Glucose
Pregnancy
2014
10 Citations (Scopus)

Genetic risk score for prediction of newborn adiposity and large-for-gestational-age birth

Chawla, R., Badon, S. E., Rangarajan, J., Reisetter, A. C., Armstrong, L. L., Lowe, L. P., Urbanek, M., Metzger, B. E., Hayes, M. G., Scholtens, D. M. & Lowe, W. L., Nov 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 11, p. E2377-E2386

Research output: Contribution to journalArticle

Adiposity
Polymorphism
Gestational Age
Single Nucleotide Polymorphism
Nucleotides
53 Citations (Scopus)

Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy

Scholtens, D. M., Muehlbauer, M. J., Daya, N. R., Stevens, R. D., Dyer, A. R., Lowe, L. P., Metzger, B. E., Newgard, C. B., Bain, J. R. & Lowe Jr, W. L., Jan 1 2014, In : Diabetes Care. 37, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

Metabolomics
Fasting
Glucose
Pregnancy
Amino Acids

The chromosome 3q25 locus associated with fetal adiposity is not associated with childhood adiposity

Chawla, R., McCance, D. R., McKenna, S., Young, I. S., Patterson, C. C., Rangarajan, J., Reisetter, A. C., Armstrong, L. L., Lowe, L. P., Metzger, B. E., Hayes, M. G., Scholtens, D. M. & Lowe, W. L., Jan 1 2014, In : Nutrition and Diabetes. 4, 9, e138.

Research output: Contribution to journalArticle

Adiposity
Chromosomes
Newborn Infant
Genome-Wide Association Study
Parturition
2013
44 Citations (Scopus)

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies

Hayes, M. G., Urbanek, M., Hivert, M. F., Armstrong, L. L., Morrison, J., Guo, C., Lowe, L. P., Scheftner, D. A., Pluzhnikov, A., Levine, D. M., McHugh, C. P., Ackerman, C. M., Bouchard, L., Brisson, D., Layden, B. T., Mirel, D., Doheny, K. F., Leya, M. V., Lown-Hecht, R. N., Dyer, A. R. & 4 others, Metzger, B. E., Reddy, T. E., Cox, N. J. & Lowe, W. L., Sep 1 2013, In : Diabetes. 62, 9, p. 3282-3291 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Mothers
Pregnancy
Glucose
Genes
5 Citations (Scopus)
C-Peptide
Pregnancy Outcome
Hyperglycemia
Testosterone
Mothers
22 Citations (Scopus)

The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study

Urbanek, M., Hayes, M. G., Armstrong, L. L., Morrison, J., Lowe, L. P., Badon, S. E., Scheftner, D., Pluzhnikov, A., Levine, D., Laurie, C. C., McHugh, C., Ackerman, C. M., Mirel, D. B., Doheny, K. F., Guo, C., Scholtens, D. M., Dyer, A. R., Metzger, B. E., Reddy, T. E., Cox, N. J. & 1 others, Lowe, W. L., Sep 1 2013, In : Human molecular genetics. 22, 17, p. 3583-3596 14 p., ddt168.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Adiposity
Chromosomes
Newborn Infant
Glucose Tolerance Test
2012
41 Citations (Scopus)

Ethnic variation in allele distribution of the androgen receptor (AR) (CAG) n repeat

Ackerman, C. M., Lowe, L. P., Lee, H., Hayes, M. G., Dyer, A. R., Metzger, B. E., Lowe, W. L. & Urbanek, M., Mar 1 2012, In : Journal of Andrology. 33, 2, p. 210-215 6 p.

Research output: Contribution to journalArticle

Androgen Receptors
Alleles
Mothers
Hispanic Americans
Ethnic Groups
297 Citations (Scopus)

Frequency of gestational diabetes mellitus at collaborating centers based on IADPSG consensus panel-recommended criteria: The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study

Sacks, D. A., Coustan, D. R., Hadden, D. R., Hod, M., Maresh, M., Oats, J. J. N., Deerochanawong, C., Persson, B., Dyer, A. R., Trimble, E. R., Metzger, B. E. & Lowe, L. P., Mar 1 2012, In : Diabetes care. 35, 3, p. 526-528 3 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Pregnancy Outcome
Hyperglycemia
Consensus
Outcome Assessment (Health Care)
41 Citations (Scopus)

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5- CHRNA3-CHRNB4) interacts with maternal selfreported smoking status during pregnancy to influence birth weight

Tyrrell, J., Huikari, V., Christie, J. T., Cavadino, A., Bakker, R., Brion, M. J. A., Geller, F., Paternoster, L., Myhre, R., Potter, C., Johnson, P. C. D., Ebrahim, S., Feenstra, B., Hartikainen, A. L., Hattersley, A. T., Hofman, A., Kaakinen, M., Lowe, L. P., Magnus, P., McConnachie, A. & 23 others, Melbye, M., Ng, J. W. Y., Nohr, E. A., Power, C., Ring, S. M., Sebert, S. P., Sengpiel, V., Taal, H. R., Watt, G. C. M., Sattar, N., Relton, C. L., Jacobsson, B., Frayling, T. M., Sørensen, T. I. A., Murray, J. C., Lawlor, D. A., Pennell, C. E., Jaddoe, V. W. V., Hypponen, E., Lowe, W. L., Jarvelin, M. R., Smith, G. D. & Freathy, R. M., Dec 1 2012, In : Human molecular genetics. 21, 24, p. 5344-5358 15 p., dds372.

Research output: Contribution to journalArticle

Nicotinic Receptors
Multigene Family
Birth Weight
Smoking
Mothers
126 Citations (Scopus)

Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Associations of maternal A1C and glucose with pregnancy outcomes

Lowe, L. P., Coustan, D. R., Metzger, B. E., Hadden, D. R., Dyer, A. R., Hod, M., Lowe, J., Oats, J. J. N., Mccance, D. R., Persson, B., Lappin, T. R. J. & Trimble, E. R., Mar 1 2012, In : Diabetes care. 35, 3, p. 574-580 7 p.

Research output: Contribution to journalArticle

Pregnancy Outcome
Hyperglycemia
Mothers
Outcome Assessment (Health Care)
Glucose
397 Citations (Scopus)

The hyperglycemia and adverse pregnancy outcome study: Associations of GDM and obesity with pregnancy outcomes

Catalano, P. M., McIntyre, H. D., Cruickshank, J. K., McCance, D. R., Dyer, A. R., Metzger, B. E., Lowe, L. P., Trimble, E. R., Coustan, D. R., Hadden, D. R., Persson, B., Hod, M. & Oats, J. J. N., Apr 1 2012, In : Diabetes care. 35, 4, p. 780-786 7 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Pregnancy Outcome
Hyperglycemia
Obesity
Outcome Assessment (Health Care)
18 Citations (Scopus)

The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy

Urbanek, M., Hayes, M. G., Lee, H., Freathy, R. M., Lowe, L. P., Ackerman, C., Jafari, N., Dyer, A. R., Cox, N. J., Dunger, D. B., Hattersley, A. T., Metzger, B. E. & Lowe, W. L., Mar 30 2012, In : PloS one. 7, 3, e32958.

Research output: Contribution to journalArticle

Alleles
Mothers
pregnancy
alleles
Phenotype
2010
62 Citations (Scopus)
Gestational Diabetes
Pregnancy Outcome
Hyperglycemia
Fasting
Mothers
73 Citations (Scopus)

Hyperglycemia and adverse pregnancy outcome study: Neonatal glycemia

Metzger, B. E., Persson, B., Lowe, L. P., Dyer, A. R., Cruickshank, J. K., Deerochanawong, C., Halliday, H. L., Hennis, A. J., Liley, H., Ng, P. C., Coustan, D. R., Hadden, D. R., Hod, M., Oats, J. J. N. & Trimble, E. R., Dec 1 2010, In : Pediatrics. 126, 6

Research output: Contribution to journalArticle

Pregnancy Outcome
Hyperglycemia
Mothers
Outcome Assessment (Health Care)
Glucose
85 Citations (Scopus)
Pregnancy Outcome
Hyperglycemia
Outcome Assessment (Health Care)
Glucose
Pregnancy
182 Citations (Scopus)
Gestational Diabetes
Pregnancy Outcome
Hyperglycemia
Outcome Assessment (Health Care)
Glucose Tolerance Test
8 Citations (Scopus)

The role of the polycystic ovary syndrome susceptibility locus D19S884 allele 8 in maternal glycemia and fetal size

Ackerman, C. M., Lowe, L. P., Lee, H., Chen, F., Hughes, E., Cholod, P., Dyer, A. R., Hayes, M. G., Metzger, B. E., Lowe, W. L. & Urbanek, M., Jan 1 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 7, p. 3242-3250 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
C-Peptide
Alleles
Mothers
Glucose
2009
376 Citations (Scopus)

Hyperglycemia and adverse pregnancy outcome (HAPO) study: Associations with neonatal anthropometrics

Metzger, B. E., Lowe, L. P., Dyer, A. R., Trimble, E. R., Sheridan, B., Hod, M., Chen, R., Yogev, Y., Coustan, D. R., Catalano, P. M., Giles, W., Lowe, J., Hadden, D. R., Persson, B. & Oats, J. J. N., Feb 1 2009, In : Diabetes. 58, 2, p. 453-459 7 p.

Research output: Contribution to journalArticle

Adiposity
Pregnancy Outcome
C-Peptide
Hyperglycemia
Outcome Assessment (Health Care)
2008
2642 Citations (Scopus)

Hyperglycemia and adverse pregnancy outcomes

Metzger, B. E., Contreras, M., Sacks, D. A., Watson, W., Dooley, S. L., Foderaro, M., Niznik, C., Bjaloncik, J., Catalano, P. M., Dierker, L., Fox, S., Gullion, L., Johnson, C., Lindsay, C. A., Makovos, H., Saker, F., Carpenter, M. W., Hunt, J., Somers, M. H., Amankwah, K. S. & 133 others, Chan, P. C., Gherson, B., Herer, E., Kapur, B., Kenshole, A., Lawrence, G., Matheson, K., Mayes, L., McLean, K., Owen, H., Cave, C., Fenty, G., Gibson, E., Hennis, A., McIntyre, G., Rotchell, Y. E., Spooner, C., Thomas, H. A. R., Gluck, J., Hadden, D. R., Halliday, H., Irwin, J., Kearney, O., McAnee, J., McCance, D. R., Mousavi, M., Traub, A. I., Cruickshank, J. K., Derbyshire, N., Dry, J., Holt, A. C., Khan, F., Lambert, C., Maresh, M., Prichard, F., Townson, C., Van Haeften, T. W., Van De Hengel, A. M. R., Visser, G. H. A., Zwart, A., Chaovarindr, U., Chotigeat, U., Deerochanawong, C., Panyasiri, I., Sanguanpong, P., Amichay, D., Golan, A., Marks, K., Mazor, M., Ronen, J., Wiznitzer, A., Chen, R., Harel, D., Hoter, N., Melamed, N., Pardo, J., Witshner, M., Yogev, Y., Bowling, F., Cowley, D., Devenish-Meares, P., Liley, H. G., McArdle, A., McIntyre, H. D., Morrison, B., Peacock, A., Tremellen, A., Tudehope, D., Chan, K. Y., Chan, N. Y., Ip, L. W., Kong, S. L., Lee, Y. L., Li, C. Y., Ng, K. F., Ng, P. C., Rogers, M. S., Wong, K. W., Edgar, M., Giles, W., Gill, A., Glover, R., Lowe, J., Mackenzie, F., Siech, K., Verma, J., Wright, A., Cao, Y. H., Chee, J. J., Koh, A., Tan, E., Rajadurai, V. J., Wee, H. Y., Yeo, G. S. H., Coustan, D., Haydon, B., Alexander, A., Hadden, D. R., Attias-Raved, O., Hod, M., Oats, J. J. N., Parry, A. F., Collard, A., Frank, A. S., Lowe, L. P., Thomas, A., Case, T., Cholod, P., Dyer, A. R., Engelman, L., Xiao, M., Yang, L., Burgess, C. I., Lappin, T. R. J., Nesbitt, G. S., Sheridan, B., Smye, M., Trimble, E. R., Coustan, D., Dyer, A. R., Hadden, D. R., Hod, M., Lowe, L. P., Oats, J. J. N., Persson, B., Trimble, E. R., Cutter, G. R., Gabbe, S. G., Hare, J. W., Wagenknecht, L. E., Chen, Y., Claman, J. & King, J., May 8 2008, In : New England Journal of Medicine. 358, 19, p. 1991-2002 12 p.

Research output: Contribution to journalArticle

Pregnancy Outcome
Hyperglycemia
Glucose
C-Peptide
Fetal Blood
2001
120 Citations (Scopus)

Prevalence and correlates of coronary calcification in black and white young adults: The coronary artery risk development in young adults (Cardia) study

Bild, D. E., Folsom, A. R., Lowe, L. P., Sidney, S., Kiefe, C., Westfall, A. O., Zheng, Z. J. & Rumberger, J., Jan 1 2001, In : Arteriosclerosis, thrombosis, and vascular biology. 21, 5, p. 852-857 6 p.

Research output: Contribution to journalArticle

Young Adult
Coronary Vessels
Calcium
LDL Cholesterol
Body Mass Index
1998
128 Citations (Scopus)

Benefit of a favorable cardiovascular risk-factor profile in middle age with respect to medicare costs

Daviglus, M. L., Liu, K., Greenland, P., Dyer, A. R., Garside, D. B., Manheim, L., Lowe, L. P., Rodin, M., Lubitz, J. & Stamler, J., Oct 15 1998, In : New England Journal of Medicine. 339, 16, p. 1122-1129 8 p.

Research output: Contribution to journalArticle

Medicare
Costs and Cost Analysis
Cardiovascular Diseases
Health Expenditures
Health Care Costs
121 Citations (Scopus)

Impact of major cardiovascular disease risk factors, particularly in combination, on 22-year mortality in women and men

Lowe, L. P., Greenland, P., Ruth, K. J., Dyer, A. R., Stamler, R. & Stamler, J., Oct 12 1998, In : Archives of Internal Medicine. 158, 18, p. 2007-2014 8 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Mortality
Confidence Intervals
Guidelines
Coronary Disease
1997
257 Citations (Scopus)
Hyperglycemia
Industry
Mortality
Cardiovascular Diseases
hydroquinone
10 Citations (Scopus)

Epidemiology of alcohol use in a group of older American Indians

Lowe, L. P., Long, C. R., Wallace, R. B. & Welty, T. K., May 1 1997, In : Annals of Epidemiology. 7, 4, p. 241-248 8 p.

Research output: Contribution to journalArticle

North American Indians
Epidemiology
Alcohols
Alcoholism
Health Status
1994
65 Citations (Scopus)

Type II diabetes and cognitive function: A population-based study of Native Americans

Lowe, L. P., Tranel, D., Wallace, R. B. & Welty, T. K., Jan 1 1994, In : Diabetes care. 17, 8, p. 891-896 6 p.

Research output: Contribution to journalArticle

North American Indians
Type 2 Diabetes Mellitus
Cognition
Population
Depression