Grants per year
Personal profile
Research Interests
My clinical and research interests focus on neurosurgical management of patients with brain and spinal cord tumors. I take care of patients with both benign as well as malignant cancer of the brain/spinal cord. In addition, part of my practice is devoted to the care of neurovascular patients, including aneurysms and arteriovenous malformations.
Training Experience
| 1997 | Internship, Johns Hopkins Hospital |
| 2002 | Fellowship, Johns Hopkins Hospital |
| 2002 | Residency, Johns Hopkins Hospital |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MS, Harvard University
… → 2010
MD, Johns Hopkins University
… → 1996
Research interests
- Acoustic Neuroma
- Biologic Therapies
- Brain Aneurysm
- Brain Arteriovenous Malformation
- Brain Cancer / Nervous System Cancer
- Neuro-Oncology
- Neurosurgery
- Skull Base Surgery
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The Identification and Rational Targeting of Immune Suppression in Malignant Chordoma
Wolinsky, J., Lee Chang, C., Lesniak, M. S. & Miska, J. M.
7/1/21 → 6/30/23
Project: Research project
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Arginine Metabolism Regulates Myeloid Immune Suppression in Glioblastoma
National Institute of Neurological Disorders and Stroke
5/1/20 → 1/31/25
Project: Research project
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Genetic Approaches to Optimize CAR T cells for Glioblastoma Therapy
Balyasnikova, I. V., Horbinski, C. M. & Lesniak, M. S.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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Developmental Research 5 Subproject for Institution # SP0045923
8/17/18 → 7/31/23
Project: Research project
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Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system
Wei, J., Song, R., Sabbagh, A., Marisetty, A., Shukla, N., Fang, D., Najem, H., Ott, M., Long, J., Zhai, L., Lesniak, M. S., James, C. D., Platanias, L., Curran, M. & Heimberger, A. B., 2022, In: OncoImmunology. 11, 1, 2062827.Research output: Contribution to journal › Article › peer-review
Open Access -
Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression
Najem, H., Ott, M., Kassab, C., Rao, A., Rao, G., Marisetty, A., Sonabend, A. M., Horbinski, C., Verhaak, R., Shankar, A., Krishnan, S. N., Varn, F. S., Arrieta, V. A., Gupta, P., Ferguson, S. D., Huse, J. T., Fuller, G. N., Long, J. P., Winkowski, D. E., Freiberg, B. A., & 5 others, May 9 2022, In: JCI Insight. 7, 9, e157612.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma
Xuan, W., Hsu, W. H., Khan, F., Dunterman, M., Pang, L., Wainwright, D. A., Ahmed, A. U., Heimberger, A. B., Lesniak, M. S. & Chen, P., Jun 2022, In: Cancer Immunology Research. 10, 6, p. 770-784 15 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer
Cordero, A., Ramsey, M. D., Kanojia, D., Fares, J., Petrosyan, E., Schwartz, C. W., Burga, R., Zhang, P., Rashidi, A., Castro, B., Xiao, T., Lee-Chang, C., Miska, J., Balyasnikova, I. V., Ahmed, A. U. & Lesniak, M. S., Jan 4 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 1, e2112491119.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Erratum: HIF-1α Is a Metabolic Switch Between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma (Cell Reports (2019) 27(1) (226–237.e4), (S2211124719303456), (10.1016/j.celrep.2019.03.029))
Miska, J., Lee-Chang, C., Rashidi, A., Muroski, M. E., Chang, A. L., Lopez-Rosas, A., Zhang, P., Panek, W. K., Cordero, A., Han, Y., Ahmed, A. U., Chandel, N. S. & Lesniak, M. S., Jun 7 2022, In: Cell reports. 39, 10, 110934.Research output: Contribution to journal › Comment/debate › peer-review
Open Access