Grants per year
Personal profile
Research Interests
My clinical and research interests focus on neurosurgical management of patients with brain and spinal cord tumors. I take care of patients with both benign as well as malignant cancer of the brain/spinal cord. In addition, part of my practice is devoted to the care of neurovascular patients, including aneurysms and arteriovenous malformations.
Training Experience
| 1997 | Internship, Johns Hopkins Hospital |
| 2002 | Fellowship, Johns Hopkins Hospital |
| 2002 | Residency, Johns Hopkins Hospital |
Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MS, Harvard University
… → 2010
MD, Johns Hopkins University
… → 1996
Research interests
- Acoustic Neuroma
- Biologic Therapies
- Brain Aneurysm
- Brain Arteriovenous Malformation
- Brain Cancer / Nervous System Cancer
- Neuro-Oncology
- Neurosurgery
- Skull Base Surgery
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Dive into the research topics where Maciej S Lesniak is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The Identification and Rational Targeting of Immune Suppression in Malignant Chordoma
Wolinsky, J., Lee Chang, C., Lesniak, M. S. & Miska, J. M.
7/1/21 → 6/30/23
Project: Research project
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Gene Silencing and NK Cell Therapy as a Nano-Immunotherapy for Glioblastoma
9/1/20 → 8/31/23
Project: Research project
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Developing a patient-derived B-cell-based vaccine, a novel therapeutic agent for glioblastomas
Neurosurgery Research and Education Foundation
7/1/20 → 11/30/21
Project: Research project
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Arginine Metabolism Regulates Myeloid Immune Suppression in Glioblastoma
National Institute of Neurological Disorders and Stroke
5/1/20 → 1/31/25
Project: Research project
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Genetic Approaches to Optimize CAR T cells for Glioblastoma Therapy
Balyasnikova, I. V., Horbinski, C. M. & Lesniak, M. S.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma
Lee-Chang, C., Miska, J., Hou, D., Rashidi, A., Zhang, P., Burga, R. A., Jusúe, I. T., Xiao, T., Arrieta, V. A., Zhang, D. Y., Lopez-Rosas, A., Han, Y., Sonabend, A. M., Horbinski, C. M., Stupp, R., Balyasnikova, I. V. & Lesniak, M. S., Jan 4 2021, In: Journal of Experimental Medicine. 218, 1Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Context-Dependent Glioblastoma–Macrophage/Microglia Symbiosis and Associated Mechanisms
Xuan, W., Lesniak, M. S., James, C. D., Heimberger, A. B. & Chen, P., Apr 2021, In: Trends in Immunology. 42, 4, p. 280-292 13 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma
Shireman, J. M., Atashi, F., Lee, G., Ali, E. S., Saathoff, M. R., Park, C. H., Savchuk, S., Baisiwala, S., Miska, J., Lesniak, M. S., James, C. D., Stupp, R., Kumthekar, P., Horbinski, C. M., Ben-Sahra, I. & Ahmed, A. U., Apr 1 2021, In: Brain. 144, 4, p. 1230-1246 17 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Emerging principles of brain immunology and immune checkpoint blockade in brain metastases
Fares, J., Ulasov, I., Timashev, P. & Lesniak, M. S., Apr 1 2021, In: Brain. 144, 4, p. 1046-1066 21 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Mesenchymal stem cells successfully deliver oncolytic virotherapy to diffuse intrinsic pontine glioma
Chastkofsky, M. I., Pituch, K. C., Katagi, H., Zannikou, M., Ilut, L., Xiao, T., Han, Y., Sonabend, A. M., Curiel, D. T., Bonner, E. R., Nazarian, J., Horbinski, C. M., James, C. D., Saratsis, A. M., Hashizume, R., Lesniak, M. S. & Balyasnikova, I. V., Mar 2021, In: Clinical Cancer Research. 27, 6, p. 1766-1777 12 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations