Grants per year
Personal profile
Research Interests
My clinical and research interests focus on neurosurgical management of patients with brain and spinal cord tumors. I take care of patients with both benign as well as malignant cancer of the brain/spinal cord. In addition, part of my practice is devoted to the care of neurovascular patients, including aneurysms and arteriovenous malformations.
Training Experience
1997 | Internship, Johns Hopkins Hospital |
2002 | Fellowship, Johns Hopkins Hospital |
2002 | Residency, Johns Hopkins Hospital |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MS, Harvard University
… → 2010
MD, Medicine, Johns Hopkins University
… → 1996
Research interests keywords
- Acoustic Neuroma
- Biologic Therapies
- Brain Aneurysm
- Brain Arteriovenous Malformation
- Brain Cancer / Nervous System Cancer
- Neuro-Oncology
- Neurosurgery
- Skull Base Surgery
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Collaborations and top research areas from the last five years
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Emerging Strategies for Therapy of Metastatic Brain Cancer
Lesniak, M. S. (PD/PI), Sonabend Worthalter, A. M. (Co-Investigator) & Stupp, R. (Co-Investigator)
8/1/24 → 7/31/31
Project: Research project
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Targeted Degradation of Survivin With PRTOACs For Glioblastoma Radiosensitization
Lesniak, M. S. (PD/PI) & Sita, T. L. (Co-Investigator)
Radiological Society of North America, Inc.
7/1/24 → 6/30/25
Project: Research project
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Targeted Degradation of Survivin With PRTOACs For Glioblastoma Radiosensitization
Lesniak, M. S. (Other) & Zhao, L. (Other)
7/1/24 → 6/30/25
Project: Research project
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Project 3
Lesniak, M. S. (PD/PI), Lesniak, M. S. (PD/PI), Lee Chang, C. (Co-Investigator), Lee Chang, C. (Co-Investigator), Miska, J. M. (Co-Investigator), Miska, J. M. (Co-Investigator), Stupp, R. (Co-Investigator) & Stupp, R. (Co-Investigator)
8/1/23 → 7/31/28
Project: Research project
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Developmental Research Core
Lesniak, M. S. (PD/PI), Lesniak, M. S. (PD/PI) & Brat, D. J. (Co-Investigator)
8/1/23 → 7/31/28
Project: Research project
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Clinical outcomes for pleomorphic xanthoastrocytoma patients
Sullivan, J. J., Chandler, J. P., Lesniak, M. S., Tate, M. C., Sonabend, A. M., Kalapurakal, J. A., Horbinski, C. M., Lukas, R. V., Kumthekar, P. U. & Sachdev, S., Feb 1 2025, In: Neuro-Oncology Practice. 12, 1, p. 45-50 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Rethinking metastatic brain cancer as a CNS disease
Fares, J., Petrosyan, E., Dmello, C., Lukas, R. V., Stupp, R. & Lesniak, M. S., Feb 2025, In: The Lancet Oncology. 26, 2, p. e111-e121Research output: Contribution to journal › Review article › peer-review
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B cell–based therapy produces antibodies that inhibit glioblastoma growth
Wang, S., Castro, B. A., Katz, J. L., Arrieta, V., Najem, H., Vazquez-Cervantes, G. I., Wan, H., Olson, I. E., Hou, D., Dapash, M., Billingham, L. K., Chia, T. Y., Wei, C., Rashidi, A., Platanias, L. C., McCortney, K., Horbinski, C. M., Stupp, R., Zhang, P. & Ahmed, A. U. & 8 others, , Oct 15 2024, In: Journal of Clinical Investigation. 134, 20, e177384.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Cancer-associated fibroblast–secreted collagen is associated with immune inhibitor receptor LAIR1 in gliomas
Tripathi, S., Najem, H., Dussold, C., Pacheco, S., Miska, J. M., McCortney, K., Steffens, A., Walshon, J., Winkowski, D., Cloney, M., Ordon, M., Gibson, W., Kemeny, H., Youngblood, M., Du, R., Mossner, J., Texakalidis, P., Sprau, A., Tate, M. C. & James, C. D. & 8 others, , Feb 15 2024, In: Journal of Clinical Investigation. 134, 4, e176613.Research output: Contribution to journal › Letter › peer-review
Open Access6 Scopus citations -
Genetics and pathogenesis of scoliosis
Petrosyan, E., Fares, J., Ahuja, C. S., Lesniak, M. S., Koski, T. R., Dahdaleh, N. S. & El Tecle, N. E., Dec 2024, In: North American Spine Society Journal. 20, 100556.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Datasets
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Research data supporting "Highly tunable perpendicularly magnetized synthetic antiferromagnets for biotechnology applications"
Vemulkar, T. (Contributor), Mansell, R. (Contributor), Petit, D. C. M. C. (Contributor), Cowburn, R. P. (Contributor) & Lesniak, M. S. (Contributor), University of Cambridge, Jun 18 2015
DOI: 10.17863/cam.69056, https://www.repository.cam.ac.uk/1810/248566
Dataset
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Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters
Kim, J. W. (Creator), Auffinger, B. (Creator), Spencer, D. A. (Creator), Miska, J. (Creator), Chang, A. L. (Creator), Kane, J. R. (Creator), Young, J. S. (Creator), Kanojia, D. (Creator), Qiao, J. (Creator), Mann, J. F. (Creator), Zhang, L. (Contributor), Wu, M. (Contributor), Ahmed, A. U. (Contributor), Aboody, K. S. (Creator), Strong, T. V. (Creator), Hébert, C. D. (Creator) & Lesniak, M. S. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3624035, https://figshare.com/collections/Single_dose_GLP_toxicity_and_biodistribution_study_of_a_conditionally_replicative_adenovirus_vector_CRAd-S-pk7_administered_by_intracerebral_injection_to_Syrian_hamsters/3624035
Dataset
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Research data supporting "The effect of underlayers on the reversal of perpendicurlarly magnetized multilayer thin films for magnetic micro- and nanoparticles"
Vemulkar, T. (Contributor), Mansell, R. (Contributor), Petit, D. C. M. C. (Contributor), Cowburn, R. P. (Contributor) & Lesniak, M. S. (Contributor), Apollo Cambridge, Feb 6 2017
DOI: 10.17863/cam.7565, https://www.repository.cam.ac.uk/1810/262328
Dataset
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Supporting data for 'Magnetic particles with perpendicular anisotropy for mechanical cancer cell destruction'
Mansell, R. (Contributor), Vemulkar, T. (Contributor), Petit, D. C. M. C. (Contributor), Cheng, Y. (Contributor), Murphy, J. (Contributor), Lesniak, M. S. (Contributor) & Cowburn, R. P. (Contributor), University of Cambridge, May 12 2017
DOI: 10.17863/cam.9594, https://www.repository.cam.ac.uk/1810/264210
Dataset