Grants per year
Personal profile
Research Interests
My clinical and research interests focus on neurosurgical management of patients with brain and spinal cord tumors. I take care of patients with both benign as well as malignant cancer of the brain/spinal cord. In addition, part of my practice is devoted to the care of neurovascular patients, including aneurysms and arteriovenous malformations.
Training Experience
| 1997 | Internship, Johns Hopkins Hospital |
| 2002 | Fellowship, Johns Hopkins Hospital |
| 2002 | Residency, Johns Hopkins Hospital |
Education/Academic qualification
MS, Harvard University
… → 2010
MD, Johns Hopkins University
… → 1996
Keywords
- Acoustic Neuroma
- Biologic Therapies
- Brain Aneurysm
- Brain Arteriovenous Malformation
- Brain Cancer / Nervous System Cancer
- Neuro-Oncology
- Neurosurgery
- Skull Base Surgery
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Neural Stem Cells
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2011 2023
Genetic Approaches to Optimize CAR T cells for Glioblastoma Therapy
Balyasnikova, I. V., Horbinski, C. M. & Lesniak, M. S.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
Antigen Receptors
Glioblastoma
Cell- and Tissue-Based Therapy
T-Cell Antigen Receptor
Glioma
Career Enhancement 3 Subproject for Institution # SP0045923
8/17/18 → 7/31/23
Project: Research project
Glioblastoma
Brain Neoplasms
Therapeutics
Neoplasms
Survival
Subproject for Institution # SP0045923 Career Enhancement 1
8/17/18 → 7/31/23
Project: Research project
Glioblastoma
Brain Neoplasms
Therapeutics
Neoplasms
Survival
Developmental Research 9 Subproject for Institution # SP0045923
8/17/18 → 7/31/23
Project: Research project
Glioblastoma
Brain Neoplasms
Research
Therapeutics
Neoplasms
Developmental Research 5 Subproject for Institution # SP0045923
8/17/18 → 7/31/23
Project: Research project
Glioblastoma
Brain Neoplasms
Research
Therapeutics
Neoplasms
Research Output 1999 2019
Cathepsin B: A sellsword of cancer progression
Mijanović, O., Branković, A., Panin, A. N., Savchuk, S., Timashev, P., Ulasov, I. & Lesniak, M. S., May 1 2019, In : Cancer Letters. 449, p. 207-214 8 p.Research output: Contribution to journal › Short survey
Cathepsin B
Cathepsins
Peptide Hydrolases
Neoplasms
Neoplasm Metastasis
Correlation of post-contrast T1-weighted MRI surface regularity, tumor bulk, and necrotic volume with Ki67 and p53 in glioblastomas
Hasse, A., Dapash, M., Jeong, Y., Ansari, S. A., Carroll, T. J., Lesniak, M. S. & Ginat, D. T., Jan 1 2019, In : Neuroradiology.Research output: Contribution to journal › Review article
Glioblastoma
Area Under Curve
Neoplasms
ROC Curve
Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer
Mooney, R., Majid, A. A., Batalla-Covello, J., Machado, D., Liu, X., Gonzaga, J., Tirughana, R., Hammad, M., Lesniak, M. S., Curiel, D. T. & Aboody, K. S., Mar 29 2019, In : Molecular Therapy - Oncolytics. 12, p. 79-92 14 p.Research output: Contribution to journal › Article
Neural Stem Cells
Adenoviridae
Ovarian Neoplasms
Cisplatin
Neoplasms
HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma
Miska, J., Lee Chang, C., Rashidi, A., Muroski, M. E., Chang, A. L., Lopez-Rosas, A., Zhang, P., Panek, W. K., Cordero, A., Han, Y., Ahmed, A. U., Chandel, N. & Lesniak, M. S., Apr 2 2019, In : Cell reports. 27, 1, p. 226-237.e4Research output: Contribution to journal › Article
Open Access
Hypoxia-Inducible Factor 1
Oxidative Phosphorylation
Glioblastoma
Immunosuppression
Switches
1
Citation
(Scopus)
Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod
Lukas, R. V., Juhász, C., Wainwright, D. A., James, C. D., Kennedy, E., Stupp, R. & Lesniak, M. S., Jan 15 2019, In : Journal of Neuro-Oncology. 141, 1, p. 111-120 10 p.Research output: Contribution to journal › Article
Indoleamine-Pyrrole 2,3,-Dioxygenase
Glioblastoma
Tryptophan
Positron-Emission Tomography
temozolomide