Maciej S Lesniak

  • 9816 Citations
19992023
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Research Output 1999 2020

2020

GCN2 is essential for CD8+ T cell survival and function in murine models of malignant glioma

Rashidi, A., Miska, J., Lee-Chang, C., Kanojia, D., Panek, W. K., Lopez-Rosas, A., Zhang, P., Han, Y., Xiao, T., Pituch, K. C., Kim, J. W., Talebian, M., Fares, J. & Lesniak, M. S., Jan 1 2020, In : Cancer Immunology, Immunotherapy. 69, 1, p. 81-94 14 p.

Research output: Contribution to journalArticle

Glioma
Cell Survival
T-Lymphocytes
Glioblastoma
Amino Acids

Remote Control of Mechanical Forces via Mitochondrial-Targeted Magnetic Nanospinners for Efficient Cancer Treatment

Chen, M., Wu, J., Ning, P., Wang, J., Ma, Z., Huang, L., Plaza, G. R., Shen, Y., Xu, C., Han, Y., Lesniak, M. S., Liu, Z. & Cheng, Y., Jan 1 2020, In : Small. 16, 3, 1905424.

Research output: Contribution to journalArticle

Oncology
Remote control
Mitochondria
Cells
Magnetic fields
2019
2 Citations (Scopus)

Activation of dopamine receptor 2 prompts transcriptomic and metabolic plasticity in glioblastoma

Caragher, S. P., Shireman, J. M., Huang, M., Miska, J., Atashi, F., Baisiwala, S., Park, C. H., Saathoff, M. R., Warnke, L., Xiao, T., Lesniak, M. S., David James, C., Meltzer, H., Tryba, A. K. & Ahmed, A. U., Mar 13 2019, In : Journal of Neuroscience. 39, 11, p. 1982-1993 12 p.

Research output: Contribution to journalArticle

Dopamine Receptors
Glioblastoma
Dopamine
Neurotransmitter Agents
Tumor Microenvironment
1 Citation (Scopus)

Cathepsin B: A sellsword of cancer progression

Mijanović, O., Branković, A., Panin, A. N., Savchuk, S., Timashev, P., Ulasov, I. & Lesniak, M. S., May 1 2019, In : Cancer Letters. 449, p. 207-214 8 p.

Research output: Contribution to journalShort survey

Cathepsin B
Cathepsins
Peptide Hydrolases
Neoplasms
Neoplasm Metastasis

Correlation of post-contrast T1-weighted MRI surface regularity, tumor bulk, and necrotic volume with Ki67 and p53 in glioblastomas

Hasse, A., Dapash, M., Jeong, Y., Ansari, S. A., Carroll, T. J., Lesniak, M. S. & Ginat, D. T., Aug 1 2019, In : Neuroradiology. 61, 8, p. 861-867 7 p.

Research output: Contribution to journalReview article

Glioblastoma
Area Under Curve
Neoplasms
ROC Curve
4 Citations (Scopus)

Current state of clinical trials in breast cancer brain metastases

Fares, J., Kanojia, D., Cordero, A., Rashidi, A., Miska, J. M., Schwartz, C. W., Savchuk, S., Ahmed, A. U., Balyasnikova, I. V., Cristofanilli, M., Gradishar, W. J. & Lesniak, M. S., Sep 20 2019, In : Neuro-Oncology Practice. 6, 5, p. 392-401 10 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Clinical Trials
Breast Neoplasms
Neoplasm Metastasis
Patient Selection
1 Citation (Scopus)

Diagnostic Clinical Trials in Breast Cancer Brain Metastases: Barriers and Innovations

Fares, J., Kanojia, D., Rashidi, A., Ahmed, A. U., Balyasnikova, I. V. & Lesniak, M. S., Dec 2019, In : Clinical breast cancer. 19, 6, p. 383-391 9 p.

Research output: Contribution to journalReview article

Brain Neoplasms
Clinical Trials
Breast Neoplasms
Neoplasm Metastasis
Circulating Neoplastic Cells

Editing Cytoprotective Autophagy in Glioma: An Unfulfilled Potential for Therapy

Ulasov, I., Fares, J., Timashev, P. & Lesniak, M. S., Jan 1 2019, (Accepted/In press) In : Trends in Molecular Medicine.

Research output: Contribution to journalReview article

Autophagy
Glioblastoma
Glioma
Therapeutics
Standard of Care
4 Citations (Scopus)

Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer

Mooney, R., Majid, A. A., Batalla-Covello, J., Machado, D., Liu, X., Gonzaga, J., Tirughana, R., Hammad, M., Dellinger, T. H., Lesniak, M. S., Curiel, D. T. & Aboody, K. S., Mar 29 2019, In : Molecular Therapy - Oncolytics. 12, p. 79-92 14 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Adenoviridae
Ovarian Neoplasms
Cisplatin
Neoplasms

FABP7 is a key metabolic regulator in HER2+ breast cancer brain metastasis

Cordero, A., Kanojia, D., Miska, J., Panek, W. K., Xiao, A., Han, Y., Bonamici, N., Zhou, W., Xiao, T., Wu, M., Ahmed, A. U. & Lesniak, M. S., Sep 12 2019, In : Oncogene. 38, 37, p. 6445-6460 16 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Brain
human ERBB2 protein
10 Citations (Scopus)

HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma

Miska, J., Lee-Chang, C., Rashidi, A., Muroski, M. E., Chang, A. L., Lopez-Rosas, A., Zhang, P., Panek, W. K., Cordero, A., Han, Y., Ahmed, A. U., Chandel, N. S. & Lesniak, M. S., Apr 2 2019, In : Cell reports. 27, 1, p. 226-237.e4

Research output: Contribution to journalArticle

Open Access
Hypoxia-Inducible Factor 1
Oxidative Phosphorylation
Glioblastoma
Immunosuppression
Switches
5 Citations (Scopus)

Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod

Lukas, R. V., Juhász, C., Wainwright, D. A., James, C. D., Kennedy, E., Stupp, R. & Lesniak, M. S., Jan 15 2019, In : Journal of Neuro-Oncology. 141, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Glioblastoma
Tryptophan
Positron-Emission Tomography
temozolomide
1 Citation (Scopus)

Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma

Hasan, T., Caragher, S. P., Shireman, J. M., Park, C. H., Atashi, F., Baisiwala, S., Lee, G., Guo, D., Wang, J. Y., Dey, M., Wu, M., Lesniak, M. S., Horbinski, C. M., James, C. D. & Ahmed, A. U., Apr 1 2019, In : Cell Death and Disease. 10, 4, 292.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
Interleukin-8
Glioma
Atlases
temozolomide
1 Citation (Scopus)

Local Application of Autologous Platelet-Rich Fibrin Patch (PRF-P) Suppresses Regulatory T Cell Recruitment in a Murine Glioma Model

Panek, W. K., Pituch, K. C., Miska, J., Kim, J. W., Rashidi, A., Kanojia, D., Lopez-Rosas, A., Han, Y., Yu, D., Chang, C. L., Kane, J. R., Zhang, P., Cordero, A. & Lesniak, M. S., Jul 1 2019, In : Molecular Neurobiology. 56, 7, p. 5032-5040 9 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Fibrin
Glioma
Blood Platelets
CD40 Ligand
1 Citation (Scopus)

Myeloid-derived suppressive cells promote B cell-mediated immunosuppression via transfer of PD-L1 in glioblastoma

Lee-Chang, C., Rashidi, A., Miska, J., Zhang, P., Pituch, K. C., Hou, D., Xiao, T., Fischietti, M., Kang, S. J., Appin, C. L., Horbinski, C., Platanias, L. C., Lopez-Rosas, A., Han, Y., Balyasnikova, I. V. & Lesniak, M. S., Jan 1 2019, In : Cancer Immunology Research. 7, 12, p. 1928-1943 16 p.

Research output: Contribution to journalArticle

Glioblastoma
Immunosuppression
B-Lymphocytes
Regulatory B-Lymphocytes
Immunosuppressive Agents
1 Citation (Scopus)

Pharmacologic modulation of nasal epithelium augments neural stem cell targeting of glioblastoma

Spencer, D., Yu, D., Morshed, R. A., Li, G., Pituch, K. C., Gao, D. X., Bertolino, N., Procissi, D., Lesniak, M. S. & Balyasnikova, I. V., Jan 1 2019, In : Theranostics. 9, 7, p. 2071-2083 13 p.

Research output: Contribution to journalArticle

Open Access
Neural Stem Cells
Nasal Mucosa
Glioblastoma
Methimazole
Oncolytic Virotherapy
Pituitary Neoplasms
Neoplasms
Area Under Curve
Magnetic Resonance Imaging
Frontal Lobe
2 Citations (Scopus)
Glioblastoma
Tretinoin
Genetic Markers
African Americans
Glioma
7 Citations (Scopus)

Repolarization of myeloid derived suppressor cells via magnetic nanoparticles to promote radiotherapy for glioma treatment

Wu, C., Muroski, M. E., Miska, J., Lee-Chang, C., Shen, Y., Rashidi, A., Zhang, P., Xiao, T., Han, Y., Lopez-Rosas, A., Cheng, Y. & Lesniak, M. S., Feb 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 16, p. 126-137 12 p.

Research output: Contribution to journalArticle

Radiotherapy
Glioma
Nanoparticles
Tumors
Phenotype
1 Citation (Scopus)

Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma

Zhang, P., Miska, J., Lee-Chang, C., Rashidi, A., Panek, W. K., An, S., Zannikou, M., Lopez-Rosas, A., Han, Y., Xiao, T., Pituch, K. C., Kanojia, D., Balyasnikova, I. V. & Lesniak, M. S., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 47, p. 23714-23723 10 p.

Research output: Contribution to journalArticle

Myeloid Cells
Glioblastoma
Radiotherapy
Ligands
Neoplasms
1 Citation (Scopus)

TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway

Ulasov, I. V., Mijanovic, O., Savchuk, S., Gonzalez-Buendia, E., Sonabend, A., Xiao, T., Timashev, P. & Lesniak, M. S., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 14
Glioblastoma
Ligands
Glioma
Nuclear Matrix
2018
3 Citations (Scopus)

A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model

Kim, J. W., Kane, J. R., Panek, W. K., Young, J. S., Rashidi, A., Yu, D., Kanojia, D., Hasan, T., Miska, J., Gómez-Lim, M. A., Ulasov, I. V., Balyasnikova, I. V., Ahmed, A. U., Wainwright, D. A. & Lesniak, M. S., Oct 14 2018, In : Neurotherapeutics. 15, 4, p. 1127-1138 12 p.

Research output: Contribution to journalArticle

Adaptive Immunity
Glioma
Dendritic Cells
Antigens
Survival
11 Citations (Scopus)

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma

Pituch, K. C., Miska, J., Krenciute, G., Panek, W. K., Li, G., Rodriguez-Cruz, T., Wu, M., Han, Y., Lesniak, M. S., Gottschalk, S. & Balyasnikova, I. V., Apr 4 2018, In : Molecular Therapy. 26, 4, p. 986-995 10 p.

Research output: Contribution to journalArticle

Adoptive Transfer
Glioblastoma
T-Cell Antigen Receptor
Glioma
Antigen Receptors
12 Citations (Scopus)

A Light-Triggered Mesenchymal Stem Cell Delivery System for Photoacoustic Imaging and Chemo-Photothermal Therapy of Triple Negative Breast Cancer

Xu, C., Feng, Q., Yang, H., Wang, G., Huang, L., Bai, Q., Zhang, C., Wang, Y., Chen, Y., Cheng, Q., Chen, M., Han, Y., Yu, Z., Lesniak, M. S. & Cheng, Y., Oct 2018, In : Advanced Science. 5, 10, 1800382.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Chemotherapy
Photoacoustic effect
stem cells
Stem cells
3 Citations (Scopus)

Autophagy in glioma cells: An identity crisis with a clinical perspective

Ulasov, I., Lenz, G. & Lesniak, M. S., Aug 1 2018, In : Cancer Letters. 428, p. 139-146 8 p.

Research output: Contribution to journalShort survey

Identity Crisis
Autophagy
Glioma
Neoplasms
Brain Neoplasms

B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma

Javier, R., Shaikh, N., Lesniak, M. S., Sonabend, A., Stupp, R., Behdad, A. & Horbinski, C., Jun 5 2018, In : Diagnostic pathology. 13, 1, 37.

Research output: Contribution to journalArticle

Lymphoma
B-Lymphocytes
Central Nervous System
Lymphoma, Large B-Cell, Diffuse
Brain Neoplasms

Gene/Viral Treatment Approaches for Malignant Brain Cancer

Kim, J. W., Pituch, K. C., Xiao, A., Young, J. S., Panek, W. K., Muroski, M. E., Rashidi, A., Kane, J. R., Kanojia, D. & Lesniak, M. S., Apr 24 2018, Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy: Second Edition. Elsevier Inc, p. 211-227 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Viral Genes
Brain Neoplasms
Genetic Therapy
Genes
Oncolytic Virotherapy
1 Citation (Scopus)

Gene Therapy and Virotherapy of Gliomas

Kim, J. W., Chang, A. L., Kane, J. R., Young, J. S., Qiao, J. & Lesniak, M. S., Jan 1 2018, In : Progress in Neurological Surgery. 32, p. 112-123 12 p.

Research output: Contribution to journalArticle

Glioma
Genetic Therapy
Oncolytic Virotherapy
Molecular Targeted Therapy
Genetic Techniques
14 Citations (Scopus)

Gross total resection and adjuvant radiotherapy most significant predictors of improved survival in patients with atypical meningioma

Rydzewski, N. R., Lesniak, M. S., Chandler, J. P., Kalapurakal, J. A., Pollom, E., Tate, M. C., Bloch, O., Kruser, T., Dalal, P. & Sachdev, S., Feb 15 2018, In : Cancer. 124, 4, p. 734-742 9 p.

Research output: Contribution to journalArticle

Adjuvant Radiotherapy
Meningioma
Survival
Radiotherapy
Neoplasms

Hospital volume and group expertise in newly diagnosed glioblastoma management

Lukas, R. V., Lesniak, M. S. & Stupp, R., Jan 1 2018, In : Journal of Neuro-Oncology. 136, 1, p. 213-214 2 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Intranasal delivery of stem cell-based therapies for the treatment of brain malignancies

Li, G., Bonamici, N., Dey, M., Lesniak, M. S. & Balyasnikova, I. V., Feb 1 2018, In : Expert Opinion on Drug Delivery. 15, 2, p. 163-172 10 p.

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
Stem Cells
Brain
Neoplasms
Brain Neoplasms
5 Citations (Scopus)

KISS1 tumor suppressor restricts angiogenesis of breast cancer brain metastases and sensitizes them to oncolytic virotherapy in vitro

Platonov, M. E., Borovjagin, A. V., Kaverina, N., Xiao, T., Kadagidze, Z., Lesniak, M., Baryshnikova, M. & Ulasov, I. V., Mar 28 2018, In : Cancer Letters. 417, p. 75-88 14 p.

Research output: Contribution to journalArticle

Oncolytic Virotherapy
Brain Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
3 Citations (Scopus)

Tamoxifen overrides autophagy inhibition in Beclin-1-deficient glioma cells and their resistance to adenovirus-mediated oncolysis via upregulation of PUMA and BAX

Kaverina, N. V., Kadagidze, Z. G., Borovjagin, A. V., Karseladze, A. I., Kim, C. K., Lesniak, M. S., Miska, J., Zhang, P., Baryshnikova, M. A., Xiao, T., Ornelles, D., Cobbs, C., Khramtsov, A. & Ulasov, I. V., Nov 15 2018, In : Oncogene. 37, 46, p. 6069-6082 14 p.

Research output: Contribution to journalArticle

Autophagy
Tamoxifen
Adenoviridae
Glioma
Up-Regulation
2017
3 Citations (Scopus)

A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model

Kim, J. W., Miska, J., Young, J. S., Rashidi, A., Kane, J. R., Panek, W. K., Kanojia, D., Han, Y., Balyasnikova, I. V. & Lesniak, M. S., Jun 1 2017, In : Molecular Therapy - Oncolytics. 5, p. 97-104 8 p.

Research output: Contribution to journalArticle

Oncolytic Virotherapy
Glioma
Immune System
Neoplasms
Survival
12 Citations (Scopus)

Bone-marrow mesenchymal stem-cell administration significantly improves outcome after retinal ischemia in rats

Mathew, B., Poston, J. N., Dreixler, J. C., Torres, L., Lopez, J., Zelkha, R., Balyasnikova, I., Lesniak, M. S. & Roth, S., Aug 1 2017, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 255, 8, p. 1581-1592 12 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Bone Marrow Cells
Stem Cells
Ischemia
Bone Marrow
20 Citations (Scopus)

Elongated nanoparticle aggregates in cancer cells for mechanical destruction with low frequency rotating magnetic field

Shen, Y., Wu, C., Uyeda, T. Q. P., Plaza, G. R., Liu, B., Han, Y., Lesniak, M. S. & Cheng, Y., Jan 1 2017, In : Theranostics. 7, 6, p. 1735-1748 14 p.

Research output: Contribution to journalArticle

Magnetic Fields
Nanoparticles
Cellular Structures
Neoplasms
Epidermal Growth Factor
6 Citations (Scopus)

Fatty Acid Uptake in T Cell Subsets Using a Quantum Dot Fatty Acid Conjugate

Muroski, M. E., Miska, J., Chang, A. L., Zhang, P., Rashidi, A., Moore, H., Lopez-Rosas, A., Han, Y. & Lesniak, M. S., Dec 1 2017, In : Scientific reports. 7, 1, 5790.

Research output: Contribution to journalArticle

Quantum Dots
T-Lymphocyte Subsets
Fatty Acids
T-Lymphocytes
Tumor Microenvironment
8 Citations (Scopus)

Hitting a moving target: Glioma stem cells demand new approaches in glioblastoma therapy

Spencer, D. A., Auffinger, B. M., Murphy, J. P., Muroski, M. E., Qiao, J., Gorind, Y. & Lesniak, M. S., Mar 1 2017, In : Current Cancer Drug Targets. 17, 3, p. 236-254 19 p.

Research output: Contribution to journalReview article

Glioblastoma
Glioma
Stem Cells
Neoplasms
Therapeutics
7 Citations (Scopus)

Hitting the nail on the head: Combining oncolytic adenovirusmediated virotherapy and immunomodulation for the treatment of glioma

Panek, W. K., Kane, J. R., Young, J. S., Rashidi, A., Kim, J. W., Kanojia, D. & Lesniak, M. S., Jan 1 2017, In : Oncotarget. 8, 51, p. 89391-89405 15 p.

Research output: Contribution to journalReview article

Oncolytic Virotherapy
Immunomodulation
Glioma
Glioblastoma
Oncolytic Viruses
4 Citations (Scopus)

Intranasal delivery of therapeutic stem cells to glioblastoma in a mouse model

Yu, D., Li, G., Lesniak, M. S. & Balyasnikova, I. V., Jun 4 2017, In : Journal of Visualized Experiments. 2017, 124, e55845.

Research output: Contribution to journalArticle

Glioblastoma
Stem cells
Stem Cells
Tumors
Brain
10 Citations (Scopus)

Magnetic particles with perpendicular anisotropy for mechanical cancer cell destruction

Mansell, R., Vemulkar, T., Petit, D. C. M. C., Cheng, Y., Murphy, J., Lesniak, M. S. & Cowburn, R. P., Dec 1 2017, In : Scientific reports. 7, 1, 4257.

Research output: Contribution to journalArticle

Anisotropy
Torque
Neoplasms
Magnetic Fields
Glioma
10 Citations (Scopus)

Mesenchymal stem cell carriers enhance antitumor efficacy of oncolytic adenoviruses in an immunocompetent mouse model

Rincón, E., Cejalvo, T., Kanojia, D., Alfranca, A., Rodríguez-Milla, M. Á., Hoyos, R. A. G., Han, Y., Zhang, L., Alemany, R., Lesniak, M. S. & García-Castro, J., Jan 1 2017, In : Oncotarget. 8, 28, p. 45415-45431 17 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Adenoviridae
Neoplasms
Human Adenoviruses
Oncolytic Virotherapy

Multiplexed nanomedicine for brain tumors: Nanosized Hercules to tame our Lernaean Hydra inside?

Panek, W. K., Khan, O. F., Yu, D. & Lesniak, M. S., Oct 1 2017, In : Nanomedicine. 12, 20, p. 2435-2439 5 p.

Research output: Contribution to journalReview article

Hydra
Nanomedicine
Medical nanotechnology
Stem Cell Factor
Brain Neoplasms
37 Citations (Scopus)

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

Yu, D., Khan, O. F., Suvà, M. L., Dong, B., Panek, W. K., Xiao, T., Wu, M., Han, Y., Ahmed, A. U., Balyasnikova, I. V., Zhang, H. F., Sun, C., Langer, R., Anderson, D. G. & Lesniak, M. S., Jul 25 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 30, p. E6147-E6156

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Glioblastoma
Brain Neoplasms
Nanoparticles
RNA Interference
172 Citations (Scopus)

Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial

Weller, M., Butowski, N., Tran, D. D., Recht, L. D., Lim, M., Hirte, H., Ashby, L., Mechtler, L., Goldlust, S. A., Iwamoto, F., Drappatz, J., O'Rourke, D. M., Wong, M., Hamilton, M. G., Finocchiaro, G., Perry, J., Wick, W., Green, J., He, Y., Turner, C. D. & 32 others, Yellin, M. J., Keler, T., Davis, T. A., Stupp, R., Sampson, J. H., Butowski, N., Campian, J., Recht, L., Lim, M., Ashby, L., Drappatz, J., Hirte, H., Iwamoto, F., Mechtler, L., Goldlust, S., Becker, K., Barnett, G., Nicholas, G., Desjardins, A., Benkers, T., Wagle, N., Groves, M., Kesari, S., Horvath, Z., Merrell, R., Curry, R., O'Rourke, J., Schuster, D., Raizer, J., Lesniak, M., ACT IV trial investigators & ACT IV trial investigators, Oct 2017, In : The Lancet Oncology. 18, 10, p. 1373-1385 13 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Survival
Brain Edema
Control Groups
19 Citations (Scopus)

Self-Assembly of Gold Nanoparticles Shows Microenvironment-Mediated Dynamic Switching and Enhanced Brain Tumor Targeting

Feng, Q., Shen, Y., Fu, Y., Muroski, M. E., Zhang, P., Wang, Q., Xu, C., Lesniak, M. S., Li, G. & Cheng, Y., Jan 1 2017, In : Theranostics. 7, 7, p. 1875-1889 15 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Gold
Nanoparticles
Nanospheres
Neoplasms
2 Citations (Scopus)

The effect of underlayers on the reversal of perpendicularly magnetized multilayer thin films for magnetic micro- and nanoparticles

Vemulkar, T., Mansell, R., Petit, D. C. M. C., Cowburn, R. P. & Lesniak, M. S., Jan 28 2017, In : Journal of Applied Physics. 121, 4, 043908.

Research output: Contribution to journalArticle

microparticles
nanoparticles
thin films
interlayers
saturation

The Role of Regulatory T Cells and Indoleamine-2,3-Dioxygenase in Brain Tumor Immunosuppression

Dey, M., Chang, A. L., Miska, J., Qiao, J. & Lesniak, M. S., Mar 2 2017, Translational Immunotherapy of Brain Tumors. Elsevier Inc., p. 33-61 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Indoleamine-Pyrrole 2,3,-Dioxygenase
Regulatory T-Lymphocytes
Brain Neoplasms
Glioma
Immunosuppression
2016

All Aboard: Mesenchymal Stem/Stromal Cells as Cell Carriers for Virotherapy

Kim, J. W., Murphy, J., Chang, A. L., Spencer, D. A., Kane, J. R., Kanojia, D., Rashidi, A., Young, J. S. & Lesniak, M. S., Nov 18 2016, Mesenchymal Stromal Cells as Tumor Stromal Modulators. Elsevier Inc, p. 475-499 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Stem cells
Mesenchymal Stromal Cells
Tumors
Neoplasms
Pathology
13 Citations (Scopus)

Anti-GITR therapy promotes immunity against malignant glioma in a murine model

Miska, J., Rashidi, A., Chang, A. L., Muroski, M. E., Han, Y., Zhang, L. & Lesniak, M. S., Dec 1 2016, In : Cancer Immunology, Immunotherapy. 65, 12, p. 1555-1567 13 p.

Research output: Contribution to journalArticle

Glucocorticoid-Induced TNFR-Related Protein
Glioma
Immunity
Antibodies
Granzymes