Maciej S Lesniak

  • 10034 Citations
19992023

Research output per year

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Research Output

2020

A Neutrophil-Inspired Supramolecular Nanogel for Magnetocaloric–Enzymatic Tandem Therapy

Zhang, Q., Wu, J., Wang, J., Wang, X., Wu, C., Chen, M., Wu, Q., Lesniak, M. S., Mi, Y., Cheng, Y. & Wang, Q., Feb 24 2020, In : Angewandte Chemie - International Edition. 59, 9, p. 3732-3738 7 p.

Research output: Contribution to journalArticle

Editing Cytoprotective Autophagy in Glioma: An Unfulfilled Potential for Therapy

Ulasov, I., Fares, J., Timashev, P. & Lesniak, M. S., Mar 2020, In : Trends in Molecular Medicine. 26, 3, p. 252-262 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

GCN2 is essential for CD8+ T cell survival and function in murine models of malignant glioma

Rashidi, A., Miska, J., Lee-Chang, C., Kanojia, D., Panek, W. K., Lopez-Rosas, A., Zhang, P., Han, Y., Xiao, T., Pituch, K. C., Kim, J. W., Talebian, M., Fares, J. & Lesniak, M. S., Jan 1 2020, In : Cancer Immunology, Immunotherapy. 69, 1, p. 81-94 14 p.

Research output: Contribution to journalArticle

Remote Control of Mechanical Forces via Mitochondrial-Targeted Magnetic Nanospinners for Efficient Cancer Treatment

Chen, M., Wu, J., Ning, P., Wang, J., Ma, Z., Huang, L., Plaza, G. R., Shen, Y., Xu, C., Han, Y., Lesniak, M. S., Liu, Z. & Cheng, Y., Jan 1 2020, In : Small. 16, 3, 1905424.

Research output: Contribution to journalArticle

2019

Activation of dopamine receptor 2 prompts transcriptomic and metabolic plasticity in glioblastoma

Caragher, S. P., Shireman, J. M., Huang, M., Miska, J., Atashi, F., Baisiwala, S., Park, C. H., Saathoff, M. R., Warnke, L., Xiao, T., Lesniak, M. S., David James, C., Meltzer, H., Tryba, A. K. & Ahmed, A. U., Mar 13 2019, In : Journal of Neuroscience. 39, 11, p. 1982-1993 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cathepsin B: A sellsword of cancer progression

Mijanović, O., Branković, A., Panin, A. N., Savchuk, S., Timashev, P., Ulasov, I. & Lesniak, M. S., May 1 2019, In : Cancer Letters. 449, p. 207-214 8 p.

Research output: Contribution to journalShort survey

1 Scopus citations

Correlation of post-contrast T1-weighted MRI surface regularity, tumor bulk, and necrotic volume with Ki67 and p53 in glioblastomas

Hasse, A., Dapash, M., Jeong, Y., Ansari, S. A., Carroll, T. J., Lesniak, M. S. & Ginat, D. T., Aug 1 2019, In : Neuroradiology. 61, 8, p. 861-867 7 p.

Research output: Contribution to journalReview article

Current state of clinical trials in breast cancer brain metastases

Fares, J., Kanojia, D., Cordero, A., Rashidi, A., Miska, J. M., Schwartz, C. W., Savchuk, S., Ahmed, A. U., Balyasnikova, I. V., Cristofanilli, M., Gradishar, W. J. & Lesniak, M. S., Sep 20 2019, In : Neuro-Oncology Practice. 6, 5, p. 392-401 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Diagnostic Clinical Trials in Breast Cancer Brain Metastases: Barriers and Innovations

Fares, J., Kanojia, D., Rashidi, A., Ahmed, A. U., Balyasnikova, I. V. & Lesniak, M. S., Dec 2019, In : Clinical breast cancer. 19, 6, p. 383-391 9 p.

Research output: Contribution to journalReview article

3 Scopus citations

Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer

Mooney, R., Majid, A. A., Batalla-Covello, J., Machado, D., Liu, X., Gonzaga, J., Tirughana, R., Hammad, M., Dellinger, T. H., Lesniak, M. S., Curiel, D. T. & Aboody, K. S., Mar 29 2019, In : Molecular Therapy - Oncolytics. 12, p. 79-92 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

FABP7 is a key metabolic regulator in HER2+ breast cancer brain metastasis

Cordero, A., Kanojia, D., Miska, J., Panek, W. K., Xiao, A., Han, Y., Bonamici, N., Zhou, W., Xiao, T., Wu, M., Ahmed, A. U. & Lesniak, M. S., Sep 12 2019, In : Oncogene. 38, 37, p. 6445-6460 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma

Miska, J., Lee-Chang, C., Rashidi, A., Muroski, M. E., Chang, A. L., Lopez-Rosas, A., Zhang, P., Panek, W. K., Cordero, A., Han, Y., Ahmed, A. U., Chandel, N. S. & Lesniak, M. S., Apr 2 2019, In : Cell reports. 27, 1, p. 226-237.e4

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod

Lukas, R. V., Juhász, C., Wainwright, D. A., James, C. D., Kennedy, E., Stupp, R. & Lesniak, M. S., Jan 15 2019, In : Journal of Neuro-Oncology. 141, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma

Hasan, T., Caragher, S. P., Shireman, J. M., Park, C. H., Atashi, F., Baisiwala, S., Lee, G., Guo, D., Wang, J. Y., Dey, M., Wu, M., Lesniak, M. S., Horbinski, C. M., James, C. D. & Ahmed, A. U., Apr 1 2019, In : Cell Death and Disease. 10, 4, 292.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Local Application of Autologous Platelet-Rich Fibrin Patch (PRF-P) Suppresses Regulatory T Cell Recruitment in a Murine Glioma Model

Panek, W. K., Pituch, K. C., Miska, J., Kim, J. W., Rashidi, A., Kanojia, D., Lopez-Rosas, A., Han, Y., Yu, D., Chang, C. L., Kane, J. R., Zhang, P., Cordero, A. & Lesniak, M. S., Jul 1 2019, In : Molecular Neurobiology. 56, 7, p. 5032-5040 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Myeloid-derived suppressive cells promote B cell-mediated immunosuppression via transfer of PD-L1 in glioblastoma

Lee-Chang, C., Rashidi, A., Miska, J., Zhang, P., Pituch, K. C., Hou, D., Xiao, T., Fischietti, M., Kang, S. J., Appin, C. L., Horbinski, C., Platanias, L. C., Lopez-Rosas, A., Han, Y., Balyasnikova, I. V. & Lesniak, M. S., Jan 1 2019, In : Cancer Immunology Research. 7, 12, p. 1928-1943 16 p.

Research output: Contribution to journalArticle

3 Scopus citations

Pharmacologic modulation of nasal epithelium augments neural stem cell targeting of glioblastoma

Spencer, D., Yu, D., Morshed, R. A., Li, G., Pituch, K. C., Gao, D. X., Bertolino, N., Procissi, D., Lesniak, M. S. & Balyasnikova, I. V., Jan 1 2019, In : Theranostics. 9, 7, p. 2071-2083 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2 Scopus citations

Repolarization of myeloid derived suppressor cells via magnetic nanoparticles to promote radiotherapy for glioma treatment

Wu, C., Muroski, M. E., Miska, J., Lee-Chang, C., Shen, Y., Rashidi, A., Zhang, P., Xiao, T., Han, Y., Lopez-Rosas, A., Cheng, Y. & Lesniak, M. S., Feb 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 16, p. 126-137 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma

Zhang, P., Miska, J., Lee-Chang, C., Rashidi, A., Panek, W. K., An, S., Zannikou, M., Lopez-Rosas, A., Han, Y., Xiao, T., Pituch, K. C., Kanojia, D., Balyasnikova, I. V. & Lesniak, M. S., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 47, p. 23714-23723 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway

Ulasov, I. V., Mijanovic, O., Savchuk, S., Gonzalez-Buendia, E., Sonabend, A., Xiao, T., Timashev, P. & Lesniak, M. S., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer. 146, 8, p. 2218-2228 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model

Kim, J. W., Kane, J. R., Panek, W. K., Young, J. S., Rashidi, A., Yu, D., Kanojia, D., Hasan, T., Miska, J., Gómez-Lim, M. A., Ulasov, I. V., Balyasnikova, I. V., Ahmed, A. U., Wainwright, D. A. & Lesniak, M. S., Oct 14 2018, In : Neurotherapeutics. 15, 4, p. 1127-1138 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma

Pituch, K. C., Miska, J., Krenciute, G., Panek, W. K., Li, G., Rodriguez-Cruz, T., Wu, M., Han, Y., Lesniak, M. S., Gottschalk, S. & Balyasnikova, I. V., Apr 4 2018, In : Molecular Therapy. 26, 4, p. 986-995 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

A Light-Triggered Mesenchymal Stem Cell Delivery System for Photoacoustic Imaging and Chemo-Photothermal Therapy of Triple Negative Breast Cancer

Xu, C., Feng, Q., Yang, H., Wang, G., Huang, L., Bai, Q., Zhang, C., Wang, Y., Chen, Y., Cheng, Q., Chen, M., Han, Y., Yu, Z., Lesniak, M. S. & Cheng, Y., Oct 2018, In : Advanced Science. 5, 10, 1800382.

Research output: Contribution to journalArticle

14 Scopus citations

Autophagy in glioma cells: An identity crisis with a clinical perspective

Ulasov, I. V., Lenz, G. & Lesniak, M. S., Aug 1 2018, In : Cancer Letters. 428, p. 139-146 8 p.

Research output: Contribution to journalShort survey

3 Scopus citations

B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma

Javier, R., Shaikh, N., Lesniak, M. S., Sonabend, A., Stupp, R., Behdad, A. & Horbinski, C., Jun 5 2018, In : Diagnostic pathology. 13, 1, 37.

Research output: Contribution to journalArticle

Gene/Viral Treatment Approaches for Malignant Brain Cancer

Kim, J. W., Pituch, K. C., Xiao, A., Young, J. S., Panek, W. K., Muroski, M. E., Rashidi, A., Kane, J. R., Kanojia, D. & Lesniak, M. S., Apr 24 2018, Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy: Second Edition. Elsevier Inc, p. 211-227 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gene Therapy and Virotherapy of Gliomas

Kim, J. W., Chang, A. L., Kane, J. R., Young, J. S., Qiao, J. & Lesniak, M. S., Jan 1 2018, In : Progress in Neurological Surgery. 32, p. 112-123 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gross total resection and adjuvant radiotherapy most significant predictors of improved survival in patients with atypical meningioma

Rydzewski, N. R., Lesniak, M. S., Chandler, J. P., Kalapurakal, J. A., Pollom, E., Tate, M. C., Bloch, O., Kruser, T., Dalal, P. & Sachdev, S., Feb 15 2018, In : Cancer. 124, 4, p. 734-742 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Hospital volume and group expertise in newly diagnosed glioblastoma management

Lukas, R. V., Lesniak, M. S. & Stupp, R., Jan 1 2018, In : Journal of Neuro-Oncology. 136, 1, p. 213-214 2 p.

Research output: Contribution to journalLetter

Intranasal delivery of stem cell-based therapies for the treatment of brain malignancies

Li, G., Bonamici, N., Dey, M., Lesniak, M. S. & Balyasnikova, I. V., Feb 1 2018, In : Expert Opinion on Drug Delivery. 15, 2, p. 163-172 10 p.

Research output: Contribution to journalReview article

5 Scopus citations

KISS1 tumor suppressor restricts angiogenesis of breast cancer brain metastases and sensitizes them to oncolytic virotherapy in vitro

Platonov, M. E., Borovjagin, A. V., Kaverina, N., Xiao, T., Kadagidze, Z., Lesniak, M., Baryshnikova, M. & Ulasov, I. V., Mar 28 2018, In : Cancer Letters. 417, p. 75-88 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Tamoxifen overrides autophagy inhibition in Beclin-1-deficient glioma cells and their resistance to adenovirus-mediated oncolysis via upregulation of PUMA and BAX

Kaverina, N. V., Kadagidze, Z. G., Borovjagin, A. V., Karseladze, A. I., Kim, C. K., Lesniak, M. S., Miska, J., Zhang, P., Baryshnikova, M. A., Xiao, T., Ornelles, D., Cobbs, C., Khramtsov, A. & Ulasov, I. V., Nov 15 2018, In : Oncogene. 37, 46, p. 6069-6082 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model

Kim, J. W., Miska, J., Young, J. S., Rashidi, A., Kane, J. R., Panek, W. K., Kanojia, D., Han, Y., Balyasnikova, I. V. & Lesniak, M. S., Jun 1 2017, In : Molecular Therapy - Oncolytics. 5, p. 97-104 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Bone-marrow mesenchymal stem-cell administration significantly improves outcome after retinal ischemia in rats

Mathew, B., Poston, J. N., Dreixler, J. C., Torres, L., Lopez, J., Zelkha, R., Balyasnikova, I., Lesniak, M. S. & Roth, S., Aug 1 2017, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 255, 8, p. 1581-1592 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Elongated nanoparticle aggregates in cancer cells for mechanical destruction with low frequency rotating magnetic field

Shen, Y., Wu, C., Uyeda, T. Q. P., Plaza, G. R., Liu, B., Han, Y., Lesniak, M. S. & Cheng, Y., Jan 1 2017, In : Theranostics. 7, 6, p. 1735-1748 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Fatty Acid Uptake in T Cell Subsets Using a Quantum Dot Fatty Acid Conjugate

Muroski, M. E., Miska, J., Chang, A. L., Zhang, P., Rashidi, A., Moore, H., Lopez-Rosas, A., Han, Y. & Lesniak, M. S., Dec 1 2017, In : Scientific reports. 7, 1, 5790.

Research output: Contribution to journalArticle

7 Scopus citations

Hitting a moving target: Glioma stem cells demand new approaches in glioblastoma therapy

Spencer, D. A., Auffinger, B. M., Murphy, J. P., Muroski, M. E., Qiao, J., Gorind, Y. & Lesniak, M. S., Mar 1 2017, In : Current Cancer Drug Targets. 17, 3, p. 236-254 19 p.

Research output: Contribution to journalReview article

9 Scopus citations

Hitting the nail on the head: Combining oncolytic adenovirusmediated virotherapy and immunomodulation for the treatment of glioma

Panek, W. K., Kane, J. R., Young, J. S., Rashidi, A., Kim, J. W., Kanojia, D. & Lesniak, M. S., Jan 1 2017, In : Oncotarget. 8, 51, p. 89391-89405 15 p.

Research output: Contribution to journalReview article

9 Scopus citations

Intranasal delivery of therapeutic stem cells to glioblastoma in a mouse model

Yu, D., Li, G., Lesniak, M. S. & Balyasnikova, I. V., Jun 4 2017, In : Journal of Visualized Experiments. 2017, 124, e55845.

Research output: Contribution to journalArticle

4 Scopus citations

Magnetic particles with perpendicular anisotropy for mechanical cancer cell destruction

Mansell, R., Vemulkar, T., Petit, D. C. M. C., Cheng, Y., Murphy, J., Lesniak, M. S. & Cowburn, R. P., Dec 1 2017, In : Scientific reports. 7, 1, 4257.

Research output: Contribution to journalArticle

13 Scopus citations

Mesenchymal stem cell carriers enhance antitumor efficacy of oncolytic adenoviruses in an immunocompetent mouse model

Rincón, E., Cejalvo, T., Kanojia, D., Alfranca, A., Rodríguez-Milla, M. Á., Hoyos, R. A. G., Han, Y., Zhang, L., Alemany, R., Lesniak, M. S. & García-Castro, J., Jan 1 2017, In : Oncotarget. 8, 28, p. 45415-45431 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Multiplexed nanomedicine for brain tumors: Nanosized Hercules to tame our Lernaean Hydra inside?

Panek, W. K., Khan, O. F., Yu, D. & Lesniak, M. S., Oct 1 2017, In : Nanomedicine. 12, 20, p. 2435-2439 5 p.

Research output: Contribution to journalReview article

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

Yu, D., Khan, O. F., Suvà, M. L., Dong, B., Panek, W. K., Xiao, T., Wu, M., Han, Y., Ahmed, A. U., Balyasnikova, I. V., Zhang, H. F., Sun, C., Langer, R., Anderson, D. G. & Lesniak, M. S., Jul 25 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 30, p. E6147-E6156

Research output: Contribution to journalArticle

39 Scopus citations

Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial

Weller, M., Butowski, N., Tran, D. D., Recht, L. D., Lim, M., Hirte, H., Ashby, L., Mechtler, L., Goldlust, S. A., Iwamoto, F., Drappatz, J., O'Rourke, D. M., Wong, M., Hamilton, M. G., Finocchiaro, G., Perry, J., Wick, W., Green, J., He, Y., Turner, C. D. & 32 others, Yellin, M. J., Keler, T., Davis, T. A., Stupp, R., Sampson, J. H., Butowski, N., Campian, J., Recht, L., Lim, M., Ashby, L., Drappatz, J., Hirte, H., Iwamoto, F., Mechtler, L., Goldlust, S., Becker, K., Barnett, G., Nicholas, G., Desjardins, A., Benkers, T., Wagle, N., Groves, M., Kesari, S., Horvath, Z., Merrell, R., Curry, R., O'Rourke, J., Schuster, D., Raizer, J., Lesniak, M., ACT IV trial investigators & ACT IV trial investigators, Oct 2017, In : The Lancet Oncology. 18, 10, p. 1373-1385 13 p.

Research output: Contribution to journalArticle

196 Scopus citations

Self-Assembly of Gold Nanoparticles Shows Microenvironment-Mediated Dynamic Switching and Enhanced Brain Tumor Targeting

Feng, Q., Shen, Y., Fu, Y., Muroski, M. E., Zhang, P., Wang, Q., Xu, C., Lesniak, M. S., Li, G. & Cheng, Y., Jan 1 2017, In : Theranostics. 7, 7, p. 1875-1889 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

The effect of underlayers on the reversal of perpendicularly magnetized multilayer thin films for magnetic micro- and nanoparticles

Vemulkar, T., Mansell, R., Petit, D. C. M. C., Cowburn, R. P. & Lesniak, M. S., Jan 28 2017, In : Journal of Applied Physics. 121, 4, 043908.

Research output: Contribution to journalArticle

2 Scopus citations

The Role of Regulatory T Cells and Indoleamine-2,3-Dioxygenase in Brain Tumor Immunosuppression

Dey, M., Chang, A. L., Miska, J., Qiao, J. & Lesniak, M. S., Mar 2 2017, Translational Immunotherapy of Brain Tumors. Elsevier Inc., p. 33-61 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

All Aboard: Mesenchymal Stem/Stromal Cells as Cell Carriers for Virotherapy

Kim, J. W., Murphy, J., Chang, A. L., Spencer, D. A., Kane, J. R., Kanojia, D., Rashidi, A., Young, J. S. & Lesniak, M. S., Nov 18 2016, Mesenchymal Stromal Cells as Tumor Stromal Modulators. Elsevier Inc, p. 475-499 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter