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Prot #VX20-121-103: A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-121 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Resi
Vertex Pharmaceuticals Incorporated
1/25/22 → 1/25/25
Project: Research project
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Prot #VX20-121-102: A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-121 Combination Therapy in Subjects With Cystic Fibrosis Who Are Heterozygous for F508del and a Minimal Function Mutation (F/MF)
Vertex Pharmaceuticals Incorporated
12/13/21 → 12/13/24
Project: Research project
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Prot #MRT5005-101: A Phase 1/2, Randomized, Double-Blind, Placebo-Controlled, Combined Single and Multiple Ascending Dose Study Evaluating the Safety, Tolerability, and Biological Activity of MRT5005 (CO-hCFTR mRNA/ICE LNP) Administered by Nebulization to
Rho, Inc., Translate Bio, Inc.
12/7/18 → 11/30/22
Project: Research project
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Prot #VX17-445-105: A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous or Heterozygous for the F508del Mutation
Greenphire, Inc., Vertex Pharmaceuticals Incorporated
7/29/18 → 7/29/23
Project: Research project
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Prot #VX17-445-103: A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del Mutation (F/F)
Greenphire, Inc., Vertex Pharmaceuticals Incorporated
7/10/18 → 8/31/22
Project: Research project
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Prot #VX14-661-110: A Phase 3, Open-label, Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment with VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Homozygous or Heterozygous for the F50
Jain, M., Lam, A. P. & Prickett, M.
Quintiles, Inc., Vertex Pharmaceuticals Incorporated
10/12/15 → 10/12/22
Project: Research project
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Therapeutics Development Center
Cystic Fibrosis Foundation Therapeutics, Inc.
1/1/14 → 3/31/22
Project: Research project