• 734 Citations
19982021
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Personal profile

Research Interests

In the clinical realm, I see both general neurology and epilepsy patients. In addition to my clinical responsibilities, my research is focused on neural prosthetics, including brain-machine interfaces (BMIs) and myoelectric computer interfaces (MCIs). BMIs are devices that translate signals from the cerebral cortex and use them to control a variety of outputs such as a computer cursor, prosthetic limb, or electrically-stimulated muscles in a paralyzed limb. BMIs could allow patients with severe paralysis (quadriplegic or “locked-in,” for example from ALS or spinal cord injury) to interact with their environment and potentially regain the use of a limb again. We are investigating the use of BMIs as a rehabilitative tool to drive changes in the brain's wiring. In addition, this technology could also provide a way for such impaired subjects to communicate by directly decoding their intended speech from the cortex. Our ultimate goal is to optimize BMIs to the point that they can safely and effectively be used in humans for long-term applications. We are also developing MCIs to help improve arm function in people who have had a stroke. We have designed a portable interface that subjects can use to play games using signals from individual muscles that help improve their arm movement.

Certifications and Licenses

Neurology

Training Experience

2006Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)

Education/Academic qualification

MD, Northwestern University Feinberg School of Medicine

… → 2002

PhD, Northwestern University

… → 2000

Keywords

  • Bioengineering
  • Brain Injury
  • Brain and Nervous System
  • Computational Neuroscience
  • Movement Control
  • Neural Engineering
  • Neurology
  • Physiology

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Grants 2007 2021

Research Output 1998 2019

2 Citations (Scopus)

Brain-Machine Interfaces: Powerful Tools for Clinical Treatment and Neuroscientific Investigations

Slutzky, M. W., Apr 1 2019, In : Neuroscientist. 25, 2, p. 139-154 16 p.

Research output: Contribution to journalReview article

Brain-Computer Interfaces
Motor Neuron Disease
Amyotrophic Lateral Sclerosis
Brain
Spinal Cord Injuries

Myoelectric Computer Interface Training for Reducing Co-Activation and Enhancing Arm Movement in Chronic Stroke Survivors: A Randomized Trial

Mugler, E. M., Tomic, G., Singh, A., Hameed, S., Lindberg, E. W., Gaide, J., Alqadi, M., Robinson, E., Dalzotto, K., Limoli, C., Jacobson, T., Lee, J. & Slutzky, M. W., Apr 1 2019, In : Neurorehabilitation and Neural Repair. 33, 4, p. 284-295 12 p.

Research output: Contribution to journalArticle

Survivors
Arm
Stroke
Muscles
Elbow
Electroencephalography
Artifacts
Brain
Electromyography
Independent component analysis
3 Citations (Scopus)

Differential representation of articulatory gestures and phonemes in precentral and inferior frontal gyri

Mugler, E. M., Tate, M. C., Livescu, K., Templer, J. W., Goldrick, M. A. & Slutzky, M. W., Nov 14 2018, In : Journal of Neuroscience. 38, 46, p. 9803-9813 11 p.

Research output: Contribution to journalArticle

Gestures
Prefrontal Cortex
Phonetics
Communication
Dental Articulators
2 Citations (Scopus)

Emergent coordination underlying learning to reach to grasp with a brain-machine interface

Vaidya, M., Balasubramanian, K., Southerland, J., Badreldin, I., Eleryan, A., Shattuck, K., Gururangan, S., Slutzky, M. W., Osborne, L., Fagg, A., Oweiss, K. & Hatsopoulos, N. G., Apr 1 2018, In : Journal of neurophysiology. 119, 4, p. 1291-1304 14 p.

Research output: Contribution to journalArticle

Brain-Computer Interfaces
Learning
Neurons
Amputation
Hand Strength