• 788 Citations
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Personal profile

Research Interests

In the clinical realm, I see both general neurology and epilepsy patients. In addition to my clinical responsibilities, my research is focused on neural prosthetics, including brain-machine interfaces (BMIs) and myoelectric computer interfaces (MCIs). BMIs are devices that translate signals from the cerebral cortex and use them to control a variety of outputs such as a computer cursor, prosthetic limb, or electrically-stimulated muscles in a paralyzed limb. BMIs could allow patients with severe paralysis (quadriplegic or “locked-in,” for example from ALS or spinal cord injury) to interact with their environment and potentially regain the use of a limb again. We are investigating the use of BMIs as a rehabilitative tool to drive changes in the brain's wiring. In addition, this technology could also provide a way for such impaired subjects to communicate by directly decoding their intended speech from the cortex. Our ultimate goal is to optimize BMIs to the point that they can safely and effectively be used in humans for long-term applications. We are also developing MCIs to help improve arm function in people who have had a stroke. We have designed a portable interface that subjects can use to play games using signals from individual muscles that help improve their arm movement.

Certifications and Licenses


Training Experience

2006Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)

Education/Academic qualification

MD, Northwestern University Feinberg School of Medicine

… → 2002

PhD, Northwestern University

… → 2000


  • Bioengineering
  • Brain Injury
  • Brain and Nervous System
  • Computational Neuroscience
  • Movement Control
  • Neural Engineering
  • Neurology
  • Physiology

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Grants 2007 2021

Research Output 1998 2019

2 Citations (Scopus)

Brain-Machine Interfaces: Powerful Tools for Clinical Treatment and Neuroscientific Investigations

Slutzky, M. W., Apr 1 2019, In : Neuroscientist. 25, 2, p. 139-154 16 p.

Research output: Contribution to journalReview article

Brain-Computer Interfaces
Motor Neuron Disease
Amyotrophic Lateral Sclerosis
Spinal Cord Injuries

Myoelectric Computer Interface Training for Reducing Co-Activation and Enhancing Arm Movement in Chronic Stroke Survivors: A Randomized Trial

Mugler, E. M., Tomic, G., Singh, A., Hameed, S., Lindberg, E. W., Gaide, J., Alqadi, M., Robinson, E., Dalzotto, K., Limoli, C., Jacobson, T., Lee, J. & Slutzky, M. W., Apr 1 2019, In : Neurorehabilitation and Neural Repair. 33, 4, p. 284-295 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Speech synthesis from ECoG using densely connected 3D convolutional neural networks

Angrick, M., Herff, C., Mugler, E., Tate, M. C., Slutzky, M. W., Krusienski, D. J. & Schultz, T., Jan 1 2019, In : Journal of Neural Engineering. 16, 3, 036019.

Research output: Contribution to journalArticle

Speech synthesis
Neural networks
Linear Models
Independent component analysis
5 Citations (Scopus)

Differential representation of articulatory gestures and phonemes in precentral and inferior frontal gyri

Mugler, E. M., Tate, M. C., Livescu, K., Templer, J. W., Goldrick, M. A. & Slutzky, M. W., Nov 14 2018, In : Journal of Neuroscience. 38, 46, p. 9803-9813 11 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
Dental Articulators