• 969 Citations

Research output per year

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Personal profile

Research Interests

In the clinical realm, I see both general neurology and epilepsy patients. In addition to my clinical responsibilities, my research is focused on neural prosthetics, including brain-machine interfaces (BMIs) and myoelectric computer interfaces (MCIs). BMIs are devices that translate signals from the cerebral cortex and use them to control a variety of outputs such as a computer cursor, prosthetic limb, or electrically-stimulated muscles in a paralyzed limb. BMIs could allow patients with severe paralysis (quadriplegic or “locked-in,” for example from ALS or spinal cord injury) to interact with their environment and potentially regain the use of a limb again. We are investigating the use of BMIs as a rehabilitative tool to drive changes in the brain's wiring. In addition, this technology could also provide a way for such impaired subjects to communicate by directly decoding their intended speech from the cortex. Our ultimate goal is to optimize BMIs to the point that they can safely and effectively be used in humans for long-term applications. We are also developing MCIs to help improve arm function in people who have had a stroke. We have designed a portable interface that subjects can use to play games using signals from individual muscles that help improve their arm movement.

Certifications and Licenses


Training Experience

2006Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)

Education/Academic qualification

MD, Northwestern University Feinberg School of Medicine

… → 2002

PhD, Northwestern University

… → 2000

Research interests

  • Bioengineering
  • Brain Injury
  • Brain and Nervous System
  • Computational Neuroscience
  • Movement Control
  • Neural Engineering
  • Neurology
  • Physiology

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Research Output

Articles from the Seventh International Brain-Computer Interface Meeting

Huggins, J. E. & Slutzky, M. W., Oct 2 2019, In : Brain-Computer Interfaces. 6, 4, p. 103-105 3 p.

Research output: Contribution to journalEditorial

Open Access

Brain-Machine Interfaces: Powerful Tools for Clinical Treatment and Neuroscientific Investigations

Slutzky, M. W., Apr 1 2019, In : Neuroscientist. 25, 2, p. 139-154 16 p.

Research output: Contribution to journalReview article

  • 10 Scopus citations

    Generating Natural, Intelligible Speech From Brain Activity in Motor, Premotor, and Inferior Frontal Cortices

    Herff, C., Diener, L., Angrick, M., Mugler, E., Tate, M. C., Goldrick, M. A., Krusienski, D. J., Slutzky, M. W. & Schultz, T., Nov 22 2019, In : Frontiers in Neuroscience. 13, 1267.

    Research output: Contribution to journalArticle

    Open Access
  • Hemicraniectomy in Traumatic Brain Injury: A Noninvasive Platform to Investigate High Gamma Activity for Brain Machine Interfaces

    Vaidya, M., Flint, R. D., Wang, P. T., Barry, A., Li, Y., Ghassemi, M., Tomic, G., Yao, J., Carmona, C., Mugler, E. M., Gallick, S., Driver, S., Brkic, N. N., Ripley, D. L., Liu, C., Kamper, D., Do, A. H. & Slutzky, M. W., Jul 1 2019, In : IEEE Transactions on Neural Systems and Rehabilitation Engineering. 27, 7, p. 1467-1472 6 p., 8697146.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Myoelectric Computer Interface Training for Reducing Co-Activation and Enhancing Arm Movement in Chronic Stroke Survivors: A Randomized Trial

    Mugler, E. M., Tomic, G., Singh, A., Hameed, S., Lindberg, E. W., Gaide, J., Alqadi, M., Robinson, E., Dalzotto, K., Limoli, C., Jacobson, T., Lee, J. & Slutzky, M. W., Apr 1 2019, In : Neurorehabilitation and Neural Repair. 33, 4, p. 284-295 12 p.

    Research output: Contribution to journalArticle