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Research Output 1989 2019

2019
1 Citation (Scopus)

A novel role for the late-onset Alzheimer’s disease (LOAD)-associated protein Bin1 in regulating postsynaptic trafficking and glutamatergic signaling

Schürmann, B., Bermingham, D. P., Kopeikina, K. J., Myczek, K., Yoon, S., Horan, K. E., Kelly, C. J., Martin-de-Saavedra, M. D., Forrest, M. P., Fawcett-Patel, J. M., Smith, K. R., Gao, R., Bach, A., Burette, A. C., Rappoport, J. Z., Weinberg, R. J., Martina, M. & Penzes, P., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Alzheimer Disease
AMPA Receptors
Synapses
Proteins
Spine
1 Citation (Scopus)

Reduced ΔFosB expression in the rat nucleus accumbens has causal role in the neuropathic pain phenotype

Pollema-Mays, S. L., Centeno, M. V., Chang, Z., Apkarian, A. & Martina, M., May 29 2019, In : Neuroscience Letters. 702, p. 77-83 7 p.

Research output: Contribution to journalArticle

Nucleus Accumbens
Neuralgia
Phenotype
Pain
Limbic System
2 Citations (Scopus)

Self-assembling vascular endothelial growth factor nanoparticles improve function in spinocerebellar ataxia type 1

Hu, Y. S., Do, J., Edamakanti, C. R., Kini, A. R., Martina, M., Stupp, S. & Opal, P., Feb 1 2019, In : Brain. 142, 2, p. 312-321 10 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Nanoparticles
Vascular Endothelial Growth Factor A
Nerve Growth Factors
Neurodegenerative Diseases
2018
2 Citations (Scopus)
3 Citations (Scopus)

Circuit-selective properties of glutamatergic inputs to the rat prelimbic cortex and their alterations in neuropathic pain

Kelly, C. J. & Martina, M., Jul 1 2018, In : Brain Structure and Function. 223, 6, p. 2627-2639 13 p.

Research output: Contribution to journalArticle

Neuralgia
Prefrontal Cortex
Optogenetics
Pyramidal Cells
Synapses
8 Citations (Scopus)

Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1

Edamakanti, C. R., Do, J., Didonna, A., Martina, M. & Opal, P., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2252-2265 14 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Purkinje Cells
Interneurons
Stem Cells
Cerebellar Diseases
8 Citations (Scopus)

The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain

Cajigas, I., Chakraborty, A., Swyter, K. R., Luo, H., Bastidas, M., Nigro, M., Morris, E. R., Chen, S., VanGompel, M. J. W., Leib, D., Kohtz, S. J., Martina, M., Koh, S., Ay, F. & Kohtz, J. D., Sep 20 2018, In : Molecular Cell. 71, 6, p. 956-972.e9

Research output: Contribution to journalArticle

Long Noncoding RNA
Prosencephalon
Interneurons
Genes
RNA
2017
18 Citations (Scopus)

Loss of M1 receptor dependent cholinergic excitation contributes to mPFC deactivation in neuropathic pain

Radzicki, D., Pollema-Mays, S. L., Sanz-Clemente, A. & Martina, M., Mar 1 2017, In : Journal of Neuroscience. 37, 9, p. 2292-2304 13 p.

Research output: Contribution to journalArticle

Neuralgia
Cholinergic Receptors
Prefrontal Cortex
Wounds and Injuries
Cholinergic Agents
2016
6 Citations (Scopus)

Early impairment of synaptic and intrinsic excitability in mice expressing ALS/dementia-linked mutant UBQLN2

Radzicki, D., Liu, E., Deng, H-X., Siddique, T. & Martina, M., Sep 20 2016, In : Frontiers in Cellular Neuroscience. 10, SEP2016, 216.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Dementia
Pyramidal Cells
Motor Neurons
Cognition
26 Citations (Scopus)
Pyramidal Cells
Neuralgia
Prefrontal Cortex
Dendrites
Chronic Pain
56 Citations (Scopus)

The indirect pathway of the nucleus accumbens shell amplifies neuropathic pain

Ren, W., Centeno, M. V., Berger, S., Wu, Y., Na, X., Liu, X., Kondapalli, J., Apkarian, A., Martina, M. & Surmeier Jr, D. J., Jan 27 2016, In : Nature Neuroscience. 19, 2, p. 220-222 3 p.

Research output: Contribution to journalArticle

Nucleus Accumbens
Neuralgia
Neurons
Peripheral Nerve Injuries
Hyperalgesia

Unipolar brush cells

Martina, M. & Sekerkova, G., Jan 1 2016, Essentials of Cerebellum and Cerebellar Disorders: A Primer for Graduate Students. Springer International Publishing, p. 213-218 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Brushes
cells
Cerebellar Cortex
cerebellum
Cerebellum
2015
15 Citations (Scopus)

Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms

Gautam, M., Jara, J. H., Sekerkova, G., Yasvoina, M. V., Martina, M. & Ozdinler, P. H., Aug 17 2015, In : Human molecular genetics. 25, 6, p. 1074-1087 14 p.

Research output: Contribution to journalArticle

Motor Neurons
Knockout Mice
Hereditary Spastic Paraplegia
Pathology
Pons
3 Citations (Scopus)
20th Century History
Neuroanatomy
Cerebellar Cortex
Mammals
Neurons

Editorial on the Honorary Cerebellum Issue for the Retirement of Enrico Mugnaini

De Zeeuw, C. I., Jaarsma, D., Voogd, J., Llinas, R. & Martina, M., Oct 1 2015, In : Cerebellum. 14, 5, p. 487-490 4 p.

Research output: Contribution to journalEditorial

20th Century History
Neuroanatomy
Retirement
Cerebellum
5 Citations (Scopus)

α-Synuclein Expression in the Mouse Cerebellum Is Restricted to VGluT1 Excitatory Terminals and Is Enriched in Unipolar Brush Cells

Lee, S. K., Sillitoe, R. V., Silva, C., Martina, M. & Sekerkova, G., Oct 1 2015, In : Cerebellum. 14, 5, p. 516-527 12 p.

Research output: Contribution to journalArticle

Vesicular Glutamate Transport Protein 1
Synucleins
Cerebellum
Presynaptic Terminals
Calbindin 2
2014
28 Citations (Scopus)

Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2

Gorrie, G. H., Fecto, F., Radzicki, D., Weiss, C., Shi, Y., Dong, H., Zhai, H., Fu, R., Liu, E., Li, S., Arrat, H., Bigio, E. H., Disterhoft, J. F., Martina, M., Mugnaini, E., Siddique, T., Deng, H. X. & Russell, D. W., Oct 7 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 40, p. 14524-14529 6 p.

Research output: Contribution to journalArticle

Dendritic Spines
Amyotrophic Lateral Sclerosis
Transgenic Mice
Dementia
Ubiquitinated Proteins
15 Citations (Scopus)
Phospholipase C beta
Cerebellum
Rodentia
Protein Isoforms
Phosphotransferases
29 Citations (Scopus)
Diagnosis-Related Groups
Methyltransferases
Spinal Ganglia
Neuralgia
Rodentia
72 Citations (Scopus)

Role of nucleus accumbens in neuropathic pain: Linked multi-scale evidence in the rat transitioning to neuropathic pain

Chang, P. C., Pollema-Mays, S. L., Centeno, M. V., Procissi, D., Contini, M., Baria, A. T., Martina, M. & Apkarian, A., Jan 1 2014, In : Pain. 155, 6, p. 1128-1139 12 p.

Research output: Contribution to journalArticle

Nucleus Accumbens
Neuralgia
Wounds and Injuries
Gene Expression
Magnetic Resonance Imaging
2013
25 Citations (Scopus)

Early onset of ataxia in moonwalker mice is accompanied by complete ablation of type II unipolar brush cells and purkinje cell dysfunction

Sekerkova, G., Kim, J. A., Nigro, M. J., Becker, E. B. E., Hartmann, J., Birnbaumer, L., Mugnaini, E. & Martina, M., Dec 13 2013, In : Journal of Neuroscience. 33, 50, p. 19689-19694 6 p.

Research output: Contribution to journalArticle

Purkinje Cells
Ataxia
Calcium
Mutation
Transient Receptor Potential Channels
25 Citations (Scopus)

Expression of background potassium channels in rat DRG is cell-specific and down-regulated in a neuropathic pain model

Pollema-Mays, S. L., Centeno, M. V., Ashford, C. J., Apkarian, A. & Martina, M., Nov 1 2013, In : Molecular and Cellular Neuroscience. 57, p. 1-9 9 p.

Research output: Contribution to journalArticle

Tandem Pore Domain Potassium Channels
Diagnosis-Related Groups
Neuralgia
Neurons
Potassium Channels
16 Citations (Scopus)
Amino Acid Transport System X-AG
Solitary Nucleus
Synaptic Transmission
Neuroglia
Glutamic Acid
29 Citations (Scopus)

Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures

Radzicki, D., Yau, H. J., Pollema-Mays, S. L., Mlsna, L., Cho, K., Koh, S. & Martina, M., Jun 17 2013, In : Journal of Neuroscience. 33, 24, p. 9920-9931 12 p.

Research output: Contribution to journalArticle

Febrile Seizures
Pyramidal Cells
Temperature
Nimodipine
Sodium Channel Blockers
2012
197 Citations (Scopus)

Abnormalities in hippocampal functioning with persistent pain

Mutso, A. A., Radzicki, D., Baliki, M. N., Huang, L., Banisadr, G., Centeno, M. V., Radulovic, J., Martina, M., Miller, R. J. & Apkarian, A., Apr 25 2012, In : Journal of Neuroscience. 32, 17, p. 5747-5756 10 p.

Research output: Contribution to journalArticle

Chronic Pain
Pain
Complex Regional Pain Syndromes
Hippocampus
Neuronal Plasticity
21 Citations (Scopus)

Acid-sensing ion channels contribute to chemosensitivity of breathing-related neurons of the nucleus of the solitary tract

Huda, R., Pollema-Mays, S. L., Chang, Z., Alheid, G. F., McCrimmon, D. R. & Martina, M., Oct 1 2012, In : Journal of Physiology. 590, 19, p. 4761-4775 15 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Solitary Nucleus
Respiration
Neurons
Amiloride
30 Citations (Scopus)

Chronic neuropathic pain-like behavior and brain-borne IL-1β

del Rey, A., Apkarian, A., Martina, M. & Besedovsky, H. O., Jan 1 2012, In : Annals of the New York Academy of Sciences. 1262, 1, p. 101-107 7 p.

Research output: Contribution to journalArticle

Neuralgia
Interleukin-1
Chronic Pain
Brain
Rats
16 Citations (Scopus)

Electrophysiological, morphological, and topological properties of two histochemically distinct subpopulations of cerebellar unipolar brush cells

Kim, J. A., Sekerkova, G., Mugnaini, E. & Martina, M., Dec 1 2012, In : Cerebellum. 11, 4, p. 1012-1021 10 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
enhanced green fluorescent protein
Calbindin 2
Carisoprodol
Patch-Clamp Techniques

Synaptic activity in X-linked mental retardation: A thorny issue

Martina, M., Feb 1 2012, In : Journal of Physiology. 590, 4, p. 653 1 p.

Research output: Contribution to journalComment/debate

X-Linked Mental Retardation
GTPase-Activating Proteins
Inhibitory Postsynaptic Potentials
Dendritic Spines
Cytoskeletal Proteins
2011
80 Citations (Scopus)

Chronic neuropathic pain-like behavior correlates with IL-1β expression and disrupts cytokine interactions in the hippocampus

Del Rey, A., Yau, H. J., Randolf, A., Centeno, M. V., Wildmann, J., Martina, M., Besedovsky, H. O. & Apkarian, A., Dec 1 2011, In : Pain. 152, 12, p. 2827-2835 9 p.

Research output: Contribution to journalArticle

Neuralgia
Interleukin-1
Chronic Pain
Hippocampus
Cytokines
36 Citations (Scopus)

Mutant TRPV4-mediated toxicity is linked to increased constitutive function in axonal neuropathies

Fecto, F., Shi, Y., Huda, R., Martina, M., Siddique, T. & Deng, H-X., May 13 2011, In : Journal of Biological Chemistry. 286, 19, p. 17281-17291 11 p.

Research output: Contribution to journalArticle

Calcium Channels
Toxicity
Clamping devices
Cytotoxicity
Cells
79 Citations (Scopus)

The unipolar brush cell: A remarkable neuron finally receiving deserved attention

Mugnaini, E., Sekerkova, G. & Martina, M., Jan 7 2011, In : Brain Research Reviews. 66, 1-2, p. 220-245 26 p.

Research output: Contribution to journalReview article

Neurons
Axons
Cerebellar Cortex
Dendrites
Cochlear Nucleus
2010
113 Citations (Scopus)

Dendritic mechanisms underlying rapid synaptic activation of fast-spiking hippocampal interneurons

Hu, H., Martina, M. & Jonas, P., Jan 1 2010, In : Science. 327, 5961, p. 52-58 7 p.

Research output: Contribution to journalArticle

Interneurons
Dendrites
Parvalbumins
Patch-Clamp Techniques
Synapses
33 Citations (Scopus)

Flufenamic acid decreases neuronal excitability through modulation of voltage-gated sodium channel gating

Yau, H. J., Baranauskas, G. & Martina, M., Oct 1 2010, In : Journal of Physiology. 588, 20, p. 3869-3882 14 p.

Research output: Contribution to journalArticle

Flufenamic Acid
Voltage-Gated Sodium Channels
Sodium Channels
Sodium
Action Potentials

Physiological properties of hippocampal neurons

Martina, M., 2010, Hippocampal Microcircuits: A Computational Modeller’s Resource Book.. Cutsuridis, V., Cobb, S., Graham, B. & Vida, I. (eds.). New York, Dordrecht, Heidelberg, London: Springer, p. 69-98

Research output: Chapter in Book/Report/Conference proceedingChapter

166 Citations (Scopus)

Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4

Deng, H-X., Klein, C. J., Yan, J., Shi, Y., Wu, Y., Fecto, F., Yau, H. J., Yang, Y., Zhai, H., Siddique, N., Hedley-Whyte, E. T., Delong, R., Martina, M., Dyck, P. J. & Siddique, T., Feb 1 2010, In : Nature Genetics. 42, 2, p. 165-169 5 p.

Research output: Contribution to journalArticle

Spinal Muscular Atrophy
Transient Receptor Potential Channels
Mutation
New England
Peripheral Nervous System Diseases
2009
239 Citations (Scopus)

Morphological and functional reorganization of rat medial prefrontal cortex in neuropathic pain

Metz, A. E., Yau, H. J., Centeno, M. V., Apkarian, A. & Martina, M., Feb 17 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 7, p. 2423-2428 6 p.

Research output: Contribution to journalArticle

Neuralgia
Prefrontal Cortex
Chronic Pain
Wounds and Injuries
N-Methylaspartate
2008
20 Citations (Scopus)

Dynamic metabotropic control of intrinsic firing in cerebellar unipolar brush cells

Russo, M. J., Yau, H. J., Nunzi, M. G., Mugnaini, E. & Martina, M., Dec 1 2008, In : Journal of Neurophysiology. 100, 6, p. 3351-3360 10 p.

Research output: Contribution to journalArticle

Action Potentials
Tandem Pore Domain Potassium Channels
Potassium
Calbindin 2
Metabotropic Glutamate Receptors
2007
44 Citations (Scopus)

Dendritic D-type potassium currents inhibit the spike afterdepolarization in rat hippocampal CA1 pyramidal neurons

Metz, A. E., Spruston, N. & Martina, M., May 15 2007, In : Journal of Physiology. 581, 1, p. 175-187 13 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Potassium
Dendrites
Action Potentials
Shaker Superfamily of Potassium Channels
31 Citations (Scopus)

Intrinsic properties and mechanisms of spontaneous firing in mouse cerebellar unipolar brush cells

Russo, M. J., Mugnaini, E. & Martina, M., Jun 1 2007, In : Journal of Physiology. 581, 2, p. 709-724 16 p.

Research output: Contribution to journalArticle

Neurons
Ruthenium Red
Patch-Clamp Techniques
Interneurons
Action Potentials
32 Citations (Scopus)

Voltage-dependent potassium currents during fast spikes of rat cerebellar Purkinje neurons: Inhibition by BDS-I toxin

Martina, M., Metz, A. E. & Bean, B. P., Jan 1 2007, In : Journal of neurophysiology. 97, 1, p. 563-571 9 p.

Research output: Contribution to journalArticle

Purkinje Cells
Potassium
Evoked Potentials
Action Potentials
Pharmacology
2006
49 Citations (Scopus)

Sodium currents activate without a Hodgkin and Huxley-type delay in central mammalian neurons

Baranauskas, G. & Martina, M., Jan 11 2006, In : Journal of Neuroscience. 26, 2, p. 671-684 14 p.

Research output: Contribution to journalArticle

Sodium
Neurons
Decapodiformes
Pyramidal Cells
Prefrontal Cortex
2005
41 Citations (Scopus)

Differential expression of TASK channels between horizontal interneurons and pyramidal cells of rat hippocampus

Taverna, S., Tkatch, T., Metz, A. E. & Martina, M., Oct 5 2005, In : Journal of Neuroscience. 25, 40, p. 9162-9170 9 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Interneurons
Hippocampus
Potassium Channels
Bupivacaine
120 Citations (Scopus)

R-type calcium channels contribute to afterdepolarization and bursting in hippocampal CA1 pyramidal neurons

Metz, A. E., Jarsky, T., Martina, M. & Spruston, N., Jun 15 2005, In : Journal of Neuroscience. 25, 24, p. 5763-5773 11 p.

Research output: Contribution to journalArticle

R-Type Calcium Channels
Pyramidal Cells
Action Potentials
Neuronal Plasticity
Ion Channels
2003
97 Citations (Scopus)

Properties and functional role of voltage-dependent potassium channels in dendrites of rat cerebellar Purkinje neurons

Martina, M., Yao, G. L. & Bean, B. P., Jul 1 2003, In : Journal of Neuroscience. 23, 13, p. 5698-5707 10 p.

Research output: Contribution to journalArticle

Purkinje Cells
Potassium Channels
Dendrites
Sodium
4-Aminopyridine
2002
94 Citations (Scopus)

Gating, modulation and subunit composition of voltage-gated K+ channels in dendritic inhibitory interneurones of rat hippocampus

Lien, C. C., Martina, M., Schultz, J. H., Ehmke, H. & Jonas, P., Jan 15 2002, In : Journal of Physiology. 538, 2, p. 405-419 15 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Interneurons
Hippocampus
4-Aminopyridine
Tetraethylammonium
2001
121 Citations (Scopus)

Cell-type-specific GABA responses and chloride homeostasis in the cortex and amygdala

Martina, M., Royer, S. & Paré, D., Dec 27 2001, In : Journal of Neurophysiology. 86, 6, p. 2887-2895 9 p.

Research output: Contribution to journalArticle

Amygdala
gamma-Aminobutyric Acid
Chlorides
Homeostasis
Interneurons
39 Citations (Scopus)

Propagation of neocortical inputs in the perirhinal cortex

Martina, M., Royer, S. & Paré, D., Apr 15 2001, In : Journal of Neuroscience. 21, 8, p. 2878-2888 11 p.

Research output: Contribution to journalArticle

Interneurons
Neurons
Synaptic Potentials
Patch-Clamp Techniques
Synapses
2000
237 Citations (Scopus)

Distal initiation and active propagation of action potentials in interneuron dendrites

Martina, M., Vida, I. & Jonas, P., Jan 25 2000, In : Science. 287, 5451, p. 295-300 6 p.

Research output: Contribution to journalArticle

Interneurons
Dendrites
Action Potentials
Sodium Channels
Potassium Channels
1998
303 Citations (Scopus)

Functional and molecular differences between voltage-gated K+ channels of fast-spiking interneurons and pyramidal neurons of rat hippocampus

Martina, M., Schultz, J. H., Ehmke, H., Monyer, H. & Jonas, P., Oct 15 1998, In : Journal of Neuroscience. 18, 20, p. 8111-8125 15 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Pyramidal Cells
Interneurons
Hippocampus
Tetraethylammonium