Grants per year
Personal profile
Research Interests
The lab of Dr. Marcus E. Peter studies various forms of cell death including apoptosis, which is a fundamental process to regulate homeostasis of all tissues and to eliminate unwanted cells specifically in the immune system. Another interest lies in the study of RNA interference and based on toxic RNAs to development a novel form of cancer treatment. The laboratory is located within the Robert H. Lurie Cancer Center at Northwestern University.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, University of Bayreuth
… → 1988
Research interests keywords
- Apoptosis
- Liver Cancer
- MicroRNA
- Cancer: Female Reproductive System (ovary, cervix, uterus)
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Collaborations and top research areas from the last five years
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Development of a novel, RNA-interference-based therapeutic to treat prostate cancer
Peter, M. E. (PD/PI) & Murmann, A. E. (Co-Investigator)
NUAgo Therapeutics, Inc., National Cancer Institute
9/19/24 → 8/31/25
Project: Research project
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Development of a DISE-inducing, short RNA therapeutic to treat solid cancers
Peter, M. E. (PD/PI), Bartom, E. T. (Co-Investigator), Kocherginsky, M. (Co-Investigator) & Murmann, A. E. (Co-Investigator)
8/1/24 → 7/31/25
Project: Research project
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CCSG Program Leadership
Arispe, L. (Other), Backman, V. (Other), Godley, L. A. (Other), Hitsman, B. L. (Other), Khan, S. A. (Other), Matei, D. E. (Other), Munshi, H. G. (Other), Peter, M. E. (Other), Rini, C. (Other), Shilatifard, A. (Other), Simon, M. A. (Other), Stupp, R. (Other), Wignall, S. (Other), Woloschak, G. E. (Other), Yanez, B. R. (Other) & Zhang, B. (Other)
8/1/23 → 7/31/25
Project: Research project
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Novel immune suppressive activities of Fas/CD95 in triple negative breast cancer
Peter, M. E. (PD/PI), Peter, M. E. (PD/PI), Bartom, E. T. (Co-Investigator) & Bartom, E. T. (Co-Investigator)
7/7/22 → 6/30/27
Project: Research project
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6mer seed toxicity and AIDS
Peter, M. E. (PD/PI), Bartom, E. T. (Co-Investigator) & Hultquist, J. F. (Co-Investigator)
National Institute of Allergy and Infectious Diseases
3/25/20 → 2/28/23
Project: Research project
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Corrigendum: miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma
Kouri, F. M., Hurley, L. A., Daniel, W. L., Day, E. S., Hua, Y., Hao, L., Peng, C. Y., Merkel, T. J., Queisser, M. A., Ritner, C., Zhang, H., James, C. D., Sznajder, J. I., Chin, L., Giljohann, D. A., Kessler, J. A., Peter, M. E., Mirkin, C. A. & Stegh, A. H., Apr 1 2024, In: Genes & development. 38, 7-8, p. 355 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer’s disease and aging
Paudel, B., Jeong, S. Y., Martinez, C. P., Rickman, A., Haluck-Kangas, A., Bartom, E. T., Fredriksen, K., Affaneh, A., Kessler, J. A., Mazzulli, J. R., Murmann, A. E., Rogalski, E., Geula, C., Ferreira, A., Heckmann, B. L., Green, D. R., Sadleir, K. R., Vassar, R. & Peter, M. E., Dec 2024, In: Nature communications. 15, 1, 264.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Unfolding a death signal to treat rheumatoid arthritis
Peter, M. E. & Bastings, M. M. C., Jul 2024, In: Nature materials. 23, 7, p. 882-883 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Analysis of the Contribution of 6-mer Seed Toxicity to HIV-1Induced Cytopathicity
Vaidyanathan, A., Taylor, H. E., Hope, T. J., D'Aquila, R. T., Bartom, E. T., Hultquist, J. F. & Peter, M. E., Jul 2023, In: Journal of virology. 97, 7Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Apoptotic cell death in disease—Current understanding of the NCCD 2023
Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Aqeilan, R. I., Arama, E., Baehrecke, E. H., Balachandran, S., Bano, D., Barlev, N. A., Bartek, J. & Bazan, N. G. & 208 others, , May 2023, In: Cell Death and Differentiation. 30, 5, p. 1097-1154 58 p.Research output: Contribution to journal › Review article › peer-review
Open Access153 Scopus citations
Datasets
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SPOROS: A pipeline to analyze 6mer/DISE seed toxicity
Bartom, E. (Creator), Kocherginsky, M. (Creator) & Peter, M. (Contributor), Code Ocean, 2021
DOI: 10.24433/co.1732496.v1, https://codeocean.com/capsule/6476502/tree/v1
Dataset
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CD95/Fas increases stemness in cancer cells by inducing a STAT1 dependent Type I interferon response
Peter, M. E. (Contributor), Gene Expression Omnibus, May 25 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE81860
Dataset