• 32398 Citations
1987 …2023
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Personal profile

Research Interests

The lab of Dr. Marcus E. Peter studies various forms of cell death including apoptosis, which is a fundamental process to regulate homeostasis of all tissues and to eliminate unwanted cells specifically in the immune system. Another interest lies in the study of RNA interference and based on toxic RNAs to development a novel form of cancer treatment. The laboratory is located within the Robert H. Lurie Cancer Center at Northwestern University.

Education/Academic qualification

PhD, University of Bayreuth, Germany

… → 1988

Research interests

  • Apoptosis
  • Liver Cancer
  • MicroRNA
  • Cancer: Female Reproductive System (ovary, cervix, uterus)

Fingerprint Dive into the research topics where Marcus Ernst Peter is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
Apoptosis Medicine & Life Sciences
Death Domain Receptor Signaling Adaptor Proteins Medicine & Life Sciences
Caspase 8 Medicine & Life Sciences
Fas Ligand Protein Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cell Death Medicine & Life Sciences
Death Domain Receptors Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2010 2023

Signal Transduction
Education
Neoplasms
Curriculum
Translational Medical Research
Alveolar Macrophages
Fibrosis
Macrophages
Systemic Scleroderma
Monocytes

Research Output 1987 2018

6mer seed toxicity in tumor suppressive microRNAs

Gao, Q. Q., Putzbach, W. E., Murmann, A. E., Chen, S., Sarshad, A. A., Peter, J. M., Bartom, E. T., Hafner, M. & Peter, M. E., Dec 1 2018, In : Nature communications. 9, 1, 4504.

Research output: Contribution to journalArticle

MicroRNAs
toxicity
Toxicity
Seed
Tumors
1 Citation (Scopus)

CD95/fas ligand mRNA is toxic to cells

Putzbach, W., Haluck-Kangas, A., Gao, Q. Q., Sarshad, A. A., Bartom, E. T., Stults, A., Qadir, A. S., Hafner, M. & Peter, M. E., Oct 1 2018, In : eLife. 7, e38621.

Research output: Contribution to journalArticle

Fas Ligand Protein
Poisons
Messenger RNA
RNA-Induced Silencing Complex
Genes
2 Citations (Scopus)

DISE: A Seed-Dependent RNAi Off-Target Effect That Kills Cancer Cells

Putzbach, W., Gao, Q. Q., Patel, M., Haluck-Kangas, A., Murmann, A. E. & Peter, M. E., Jan 1 2018, In : Trends in Cancer. 4, 1, p. 10-19 10 p.

Research output: Contribution to journalReview article

RNA Interference
Seeds
Genes
Neoplasms
Small Interfering RNA
4 Citations (Scopus)

Identification of DISE-inducing shRNAs by monitoring cellular responses

Patel, M. & Peter, M. E., Feb 16 2018, In : Cell Cycle. 17, 4, p. 506-514 9 p.

Research output: Contribution to journalArticle

Genes
Neoplasms
Fas Ligand Protein
Gene Targeting
Poisons
321 Citations (Scopus)

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 others, Blomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalReview article

Terminology
Cell Death
Apoptosis
Cell Aging
Autophagy