Personal profile

Research Interests

Signaling of death receptors with emphasis on Fas. The role of microRNA in tumor progression.

Education / Academic qualification

PhD, University of Bayreuth, Germany

… → 1988

Keywords

  • cervix
  • Cancer: Female Reproductive System (ovary
  • MicroRNA
  • Liver Cancer
  • Apoptosis
  • uterus)

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 19 Similar Profiles
Apoptosis Medicine & Life Sciences
Death Domain Receptor Signaling Adaptor Proteins Medicine & Life Sciences
Caspase 8 Medicine & Life Sciences
Fas Ligand Protein Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Death Domain Receptors Medicine & Life Sciences
Cell Death Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences

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Research Output 1987 2018

DISE: A Seed-Dependent RNAi Off-Target Effect That Kills Cancer Cells

Putzbach, W., Gao, Q. Q., Patel, M., Haluck-Kangas, A., Murmann, A. E. & Peter, M. E. Jan 1 2018 In : Trends in Cancer. 4, 1, p. 10-19 10 p.

Research output: Contribution to journalReview article

RNA Interference
Seeds
Genes
Neoplasms
Small Interfering RNA

Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells

Murmann, A. E., Gao, Q. Q., Putzbach, W. E., Patel, M., Bartom, E. T., Law, C. Y., Bridgeman, B., Chen, S., Mcmahon, K. M., Thaxton, C. S. & Peter, M. E. Jan 1 2018 (Accepted/In press) In : EMBO Reports.

Research output: Contribution to journalArticle

Trinucleotide Repeats
Poisons
Small Interfering RNA
Cells
Trinucleotide Repeat Expansion
3 Citations

Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation

Calvert, A. E. , Chalastanis, A. , Wu, Y. , Hurley, L. A. , Kouri, F. M. , Bi, Y. , Kachman, M. , May, J. L. , Bartom, E. , Hua, Y. , Mishra, R. K. , Schiltz, G. E. , Dubrovskyi, O. , Mazar, A. P. , Peter, M. E. , Zheng, H. , James, C. D. , Burant, C. F. , Chandel, N. S. , Davuluri, R. V. & 2 others Horbinski, C. & Stegh, A. H. May 30 2017 In : Cell Reports. 19, 9, p. 1858-1873 16 p.

Research output: Contribution to journalArticle

Bearings (structural)
Isocitrate Dehydrogenase
Gene encoding
Methylation
Differentiation Antigens
5 Citations

CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response

Qadir, A. S., Ceppi, P., Brockway, S., Law, C., Mu, L., Khodarev, N. N., Kim, J., Zhao, J. C., Putzbach, W., Murmann, A. E., Chen, Z., Chen, W., Liu, X., Salomon, A. R., Liu, H., Weichselbaum, R. R., Yu, J. & Peter, M. E. Mar 7 2017 In : Cell Reports. 18, 10, p. 2373-2386 14 p.

Research output: Contribution to journalArticle

STAT1 Transcription Factor
Interferon Type I
Cells
Neoplastic Stem Cells
Stem cells
3 Citations

Induction of DISE in ovarian cancer cells in vivo

Murmann, A. E., McMahon, K. M., Haluck-Kangas, A., Ravindran, N., Patel, M., Law, C. Y., Brockway, S., Wei, J. J., Thaxton, C. S. & Peter, M. E. Oct 17 2017 In : Oncotarget. 8, 49, p. 84643-84658 16 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Fas Ligand Protein
Small Interfering RNA
Genes
Nanoparticles