Marek-Marsel Mesulam

  • 57381 Citations
1972 …2017

Research Output 1972 2017

2017
1 Citations

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A., Lee, S. E., Wojta, K., Ramos, E. M., Klein, E., Chen, J., Boxer, A. L., Gorno-Tempini, M. L., Geschwind, D. H., Schlotawa, L., Ogryzko, N. V., Bigio, E. H., Rogalski, E., Weintraub, S., Mesulam, M. M., Fleming, A., Coppola, G., Miller, B. L., Rubinsztein, D. C. & Tauopathy Genetics Consortium Apr 1 2017 In : Brain : a journal of neurology. 140, 4, p. 1128-1146 19 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Autophagy
Zebrafish
Alleles
Frontotemporal dementia
1 Citations

Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS

Genç, B., Jara, J. H., Lagrimas, A. K. B., Pytel, P., Roos, R. P., Mesulam, M. M., Geula, C., Bigio, E. H. & Özdinler, P. H. Feb 6 2017 In : Scientific Reports. 7, 41765

Research output: Contribution to journalArticle

Dendrites
Pathology
Motor Cortex
Alzheimer Disease
Frontotemporal Dementia

Case 1-2017: A 70-year-old woman with gradually progressive loss of language

Mesulam, M. M., Dickerson, B. C., Sherman, J. C., Hochberg, D., Gonzalez, R. G., Johnson, K. A. & Frosch, M. P. Jan 12 2017 In : New England Journal of Medicine. 376, 2, p. 158-167 10 p.

Research output: Contribution to journalArticle

1 Citations

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia

Oboudiyat, C., Gefen, T., Varelas, E., Weintraub, S., Rogalski, E., Bigio, E. H. & Mesulam, M. M. 2017 In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Dementia
Alzheimer Disease
Pathology
Amyloid

Evidence for an early innate immune response in the motor cortex of ALS

Jara, J. H., Genç, B., Stanford, M. J., Pytel, P., Roos, R. P., Weintraub, S., Mesulam, M. M., Bigio, E. H., Miller, R. J. & Özdinler, P. H. Jun 26 2017 In : Journal of Neuroinflammation. 14, 1, 129

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Motor Cortex
Innate Immunity
Chemokine CCL2
CCR2 Receptors
Primary Progressive Aphasia
Atrophy
Broca Aphasia
Neurodegenerative Diseases
Healthy Volunteers
4 Citations

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis

Ward, M. E. , Chen, R. , Huang, H. Y. , Ludwig, C. , Telpoukhovskaia, M. , Taubes, A. , Boudin, H. , Minami, S. S. , Reichert, M. , Albrecht, P. , Gelfand, J. M. , Cruz-Herranz, A. , Cordano, C. , Alavi, M. V. , Leslie, S. , Seeley, W. W. , Miller, B. L. , Bigio, E. , Mesulam, M. M. , Bogyo, M. S. & 6 others Mackenzie, I. R., Staropoli, J. F., Cotman, S. L., Huang, E. J., Gan, L. & Green, A. J. Apr 12 2017 In : Science Translational Medicine. 9, 385, eaah5642

Research output: Contribution to journalArticle

Neuronal Ceroid-Lipofuscinoses
Haploinsufficiency
Mutation
Frontotemporal Dementia
Lysosomal Storage Diseases
2 Citations

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

Huang, M. , Yang, W. , Feng, Q. , Chen, W. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Shaw, L. M. , Kaye, J. , Quinn, J. , Silbert, L. , Lind, B. & 222 others Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Morris, J. C., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K. Jan 12 2017 In : Scientific Reports. 7, 39880

Research output: Contribution to journalArticle

Mild Cognitive Impairment
Alzheimer Disease
Brain Diseases
Neuroimaging
Early Diagnosis

Rates of cortical atrophy in adults 80 years and older with superior vs average episodic memory

Cook, A. H., Sridhar, J., Ohm, D., Rademaker, A., Mesulam, M. M., Weintraub, S. & Rogalski, E. Apr 4 2017 In : JAMA - Journal of the American Medical Association. 317, 13, p. 1373-1375 3 p.

Research output: Contribution to journalLetter

Episodic Memory
Atrophy
Primary Progressive Aphasia
Atrophy
Recognition (Psychology)
Episodic Memory
Neuropsychological Tests
2016
5 Citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Karch, C. M. , Ezerskiy, L. A. , Bertelsen, S. , Goate, A. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Baldwin, C. T. , Barber, R. , Barmada, M. M. , Barnes, L. L. , Beach, T. G. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. , Boeve, B. F. & 145 others Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Crane, P. K., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Kamboh, M. I., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukull, W. A., LaFerla, F. M., Lah, J. J., Larson, E. B., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E., Yu, L. & Alzheimer's Disease Genetics Consortium (ADGC) Feb 1 2016 In : PLoS ONE. 11, 2, e0148717

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer Disease
Gene Expression
loci
Cyclic AMP Receptor Protein
3 Citations

Aphasic variant of Alzheimer disease

Rogalski, E., Sridhar, J., Rader, B., Martersteck, A., Chen, K., Cobia, D., Thompson, C. K., Weintraub, S., Bigio, E. H. & Mesulam, M. M. Sep 27 2016 In : Neurology. 87, 13, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Primary Progressive Aphasia
Biological Markers
Atrophy
Aphasia
2 Citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Adams, P. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Asthana, S. , Atwood, C. S. , Baldwin, C. T. , Barber, R. C. , Barmada, M. M. , Barnes, L. L. , Barral, S. , Beach, T. G. , Becker, J. T. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. & 175 others Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., David, C. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Evans, D. A., Faber, K. M., Fairchild, T. J., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Hardy, J., Harrell, L. E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, I. M., Karydas, A., Katz, M. J., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Kukull, W. A., Kunkle, B. W., LaFerla, F. M., Lah, J. J., Larson, E. B., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lipton, R. B., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., Naj, A. C., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., St George-Hyslop, P., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Wendland, J. R., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Winslow, A. R., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Younkin, S. G., Yu, C. E., Yu, L., Ridge, P. G., Hoyt, K. B., Boehme, K., Crane, P. K., Haines, J. L., Mayeux, R., Farrer, L. A., Pericak-Vance, M. A., Schellenberg, G. D., Kauwe, J. S. K. & Alzheimer's Disease Genetics Consortium (ADGC) May 1 2016 In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Amyloid beta-Protein Precursor
Myeloid Cells
Genome
21 Citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Risacher, S. L. , McDonald, B. C. , Tallman, E. F. , West, J. D. , Farlow, M. R. , Unverzagt, F. W. , Gao, S. , Boustani, M. , Crane, P. K. , Petersen, R. C. , Jack, C. R. , Jagust, W. J. , Aisen, P. S. , Weiner, M. W. , Saykin, A. J. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Morris, J. & 329 others Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P. J., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S. G., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., De Toledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., McAdams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Hake, A. M., Matthews, B. R., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pasternak, S., Rachinsky, I., Rogers, J., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Boles Ponto, L. L., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B., Fargher, K., Neylan, T., Grafman, J., Davis, M., Morrison, R., Hayes, J., Finley, S., Friedl, K., Fleischman, D., Arfanakis, K., Doraiswamy, P. M., James, O., Goldstei, B., Martin, K. S., Massoglia, D., Brawman-Mintzer, O., Martinez, W., Ros, H., Behan, K., Sirrel, S. A., Johnson, S. C., Fruehling, J. J., Harding, S., Peskind, E. R., Petrie, E. C., Li, G., Yesavage, J. A., Furst, A. J., Chao, S. & Alzheimer's Disease Neuroimaging Initiative Jun 1 2016 In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Cognition
Atrophy
Brain
Neuroimaging

Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions

Kim, G., Ahmadian, S. S., Peterson, M., Parton, Z., Memon, R., Weintraub, S., Rademaker, A., Bigio, E., Mesulam, M. M. & Geula, C. Feb 16 2016 In : Neurology. 86, 7, p. 627-636 10 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Microglia
Pathology
Mutation
DNA-Binding Proteins
1 Citations

Communication Bridge: A pilot feasibility study of Internet-based speech-language therapy for individuals with progressive aphasia

Rogalski, E. J., Saxon, M., McKenna, H., Wieneke, C., Rademaker, A., Corden, M. E., Borio, K., Mesulam, M. M. & Khayum, B. Nov 1 2016 In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 4, p. 213-221 9 p.

Research output: Contribution to journalArticle

Language Therapy
Speech Therapy
Aphasia
Feasibility Studies
Internet
34 Citations

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

Iturria-Medina, Y. , Sotero, R. C. , Toussaint, P. J. , Mateos-Pérez, J. M. , Evans, A. C. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Shaw, L. M. , Khachaturian, Z. , Sorensen, G. , Kuller, L. & 296 others Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Leon, S., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., De Toledo-Morrell, L., Shah, R. C., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Doraiswamy, P. M., Petrella, J. R., Wong, T. Z., Arnold, S. E., Karlawish, J. H., Wolk, D., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., DeVous, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Anderson, H. S., Swerdlow, R. H., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A., Matthews, B. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Bernick, C., Munic, D., Kerwin, D., Mesulam, M. M., Lipowski, K., Wu, C. K., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Frey, M., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Allard, J., Lerner, A., Ogrocki, P., Hudson, L., Fletcher, E., Carmichael, O., Olichney, J., DeCarli, C., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Santulli, R. B., Kitzmiller, T. J., Schwartz, E. S., Sink, K. M., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Mintzer, J., Spicer, K., Bachman, D., Finger, E., Pasternak, S., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ponto, L. L. B., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K., Raj, B. A., Neylan, T., Grafman, J., Davis, M., Morrison, R., Hayes, J., Finley, S., Friedl, K., Fleischman, D., Arfanakis, K., James, O., Massoglia, D., Fruehling, J. J., Harding, S., Peskind, E. R., Petrie, E. C., Li, G., Yesavage, J. A., Taylor, J. L., Furst, A. J. & The Alzheimer's Disease Neuroimaging Initiative Jun 21 2016 In : Nature Communications. 7, 11934

Research output: Contribution to journalArticle

Blood Vessels
Alzheimer Disease
Supravalvular Aortic Stenosis
Biological Markers
Brain

Eye movements as probes of lexico-semantic processing in a patient with primary progressive aphasia

Seckin, M., Mesulam, M. M., Rademaker, A. W., Voss, J. L., Weintraub, S., Rogalski, E. J. & Hurley, R. S. Jan 2 2016 In : Neurocase. 22, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Eye movements
Primary Progressive Aphasia
Eye Movements
Semantics
Primary progressive aphasia
2 Citations

Frontotemporal networks and behavioral symptoms in primary progressive aphasia

D'Anna, L., Mesulam, M. M., Thiebaut De Schotten, M., Dell'Acqua, F., Murphy, D., Wieneke, C., Martersteck, A., Cobia, D., Rogalski, E. & Catani, M. Apr 12 2016 In : Neurology. 86, 15, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Behavioral Symptoms
Temporal Lobe
Diffusion Tensor Imaging
Frontal Lobe
4 Citations

Is in vivo amyloid distribution asymmetric in primary progressive aphasia?

Martersteck, A., Murphy, C., Rademaker, A., Wieneke, C., Weintraub, S., Chen, K., Mesulam, M. M. & Rogalski, E. Mar 1 2016 In : Annals of Neurology. 79, 3, p. 496-501 6 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Amyloid
Parietal Lobe
Positron-Emission Tomography
Dementia
2 Citations

Neuropathologic associations of learning and memory in primary progressive aphasia

Kielb, S., Cook, A., Wieneke, C., Rademaker, A., Bigio, E. H., Mesulam, M. M., Rogalski, E. & Weintraub, S. Jul 1 2016 In : JAMA Neurology. 73, 7, p. 846-852 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Association Learning
Alzheimer Disease
Frontotemporal Lobar Degeneration
Autopsy
4 Citations

Neuropathology of autosomal dominant Alzheimer disease in the national Alzheimer coordinating center database

Ringman, J. M., Monsell, S., Ng, D. W., Zhou, Y., Nguyen, A., Coppola, G., Van Berlo, V., Mendez, M. F., Tung, S., Weintraub, S., Mesulam, M. M., Bigio, E. H., Gitelman, D. R., Fisher-Hubbard, A. O., Albin, R. L. & Vinters, H. V. 2016 In : Journal of Neuropathology and Experimental Neurology. 75, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Mutation
Cerebral Amyloid Angiopathy
Lewy Bodies
Codon
1 Citations

Postmortem Adult Human Microglia Proliferate in Culture to High Passage and Maintain Their Response to Amyloid-β

Guo, L., Rezvanian, A., Kukreja, L., Hoveydai, R., Bigio, E. H., Mesulam, M. M., El Khoury, J. & Geula, C. 2016 In : Journal of Alzheimer's Disease. 54, 3, p. 1157-1167 11 p.

Research output: Contribution to journalArticle

Microglia
Amyloid
Brain
Primates
Rodentia
38 Citations

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H. , Zhang, J. , Makinson, S. R. , Cahill, M. K. , Kelley, K. W. , Huang, H. Y. , Shang, Y. , Oldham, M. C. , Martens, L. H. , Gao, F. , Coppola, G. , Sloan, S. A. , Hsieh, C. L. , Kim, C. C. , Bigio, E. H. , Weintraub, S. , Mesulam, M. M. , Rademakers, R. , MacKenzie, I. R. , Seeley, W. W. & 8 others Karydas, A., Miller, B. L., Borroni, B., Ghidoni, R., Farese, R. V., Paz, J. T., Barres, B. A. & Huang, E. J. May 5 2016 In : Cell. 165, 4, p. 921-935 15 p.

Research output: Contribution to journalArticle

Complement Activation
Microglia
Cape Verde
Genes
Cyclic AMP Receptor Protein
2 Citations

Proof of concept demonstration of optimal composite MRI endpoints for clinical trials

Edland, S. D., Ard, M. C., Sridhar, J., Cobia, D., Martersteck, A., Mesulam, M. M. & Rogalski, E. J. Sep 1 2016 In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 3, p. 177-181 5 p.

Research output: Contribution to journalArticle

Atrophy
Clinical Trials
Primary Progressive Aphasia
Temporal Lobe
Biological Markers
1 Citations

Toward a consensus recommendation for defining the asymptomatic-preclinical phases of putative Alzheimer's disease?

Khachaturian, Z. S., Mesulam, M. M., Mohs, R. C. & Khachaturian, A. S. Mar 1 2016 In : Alzheimer's and Dementia. 12, 3, p. 213-215 3 p.

Research output: Contribution to journalEditorial

Alzheimer Disease
2015
4 Citations

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M. , Reitz, C. , Cheng, R. , Vardarajan, B. N. , Jun, G. , Sato, C. , Naj, A. , Rajbhandary, R. , Wang, L. S. , Valladares, O. , Lin, C. F. , Larson, E. B. , Graff-Radford, N. R. , Evans, D. , De Jager, P. L. , Crane, P. K. , Buxbaum, J. D. , Murrell, J. R. , Raj, T. , Ertekin-Taner, N. & 153 others Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L. Nov 1 2015 In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Datasets
Single Nucleotide Polymorphism
Genes
16 Citations

Asymmetric connectivity between the anterior temporal lobe and the language network

Hurley, R. S., Bonakdarpour, B., Wang, X. & Mesulam, M. M. Mar 2 2015 In : Journal of Cognitive Neuroscience. 27, 3, p. 464-473 10 p.

Research output: Contribution to journalArticle

language
Temporal lobe
Temporal Lobe
network
region
9 Citations

Benefits of mindfulness training for patients with progressive cognitive decline and their caregivers

Paller, K. A., Creery, J. D., Florczak, S. M., Weintraub, S., Mesulam, M. M., Reber, P. J., Kiragu, J., Rooks, J., Safron, A., Morhardt, D., O'Hara, M., Gigler, K. L., Molony, J. M. & Maslar, M. May 6 2015 In : American Journal of Alzheimer's Disease and other Dementias. 30, 3, p. 257-267 11 p.

Research output: Contribution to journalArticle

Mindfulness
Caregivers
Neurodegenerative Diseases
Alzheimer Disease
Sleep
2 Citations

Diffuse leukoencephalopathy with spheroids presenting as primary progressive aphasia

Oboudiyat, C., Bigio, E. H., Bonakdarpour, B., Baker, M. C., Rademakers, R., Weintraub, S. & Mesulam, M. M. Aug 18 2015 In : Neurology. 85, 7, p. 652-653 2 p.

Research output: Contribution to journalShort survey

Primary Progressive Aphasia
Memantine
Leukoencephalopathies
Pravastatin
Learning Disorders
44 Citations

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Ayton, S. , Faux, N. G. , Bush, A. I. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Shaw, L. M. , Khachaturian, Z. , Sorensen, G. , Kuller, L. , Raichle, M. , Paul, S. & 294 others Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Leon, S., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., De Toledo-Morrell, L., Shah, R. C., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Doraiswamy, P. M., Petrella, J. R., Wong, T. Z., Arnold, S. E., Karlawish, J. H., Wolk, D., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., DeVous, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Anderson, H. S., Swerdlow, R. H., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Matthews, B. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Bernick, C., Munic, D., Kerwin, D., Mesulam, M. M., Lipowski, K., Wu, C. K., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Frey, M., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Allard, J., Lerner, A., Ogrocki, P., Hudson, L., Fletcher, E., Carmichael, O., Olichney, J., DeCarli, C., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Santulli, R. B., Kitzmiller, T. J., Schwartz, E. S., Sink, K. M., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Mintzer, J., Spicer, K., Bachman, D., Finger, E., Pasternak, S., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Boles Ponto, L. L., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K., Raj, B. A., Neylan, T., Grafman, J., Davis, M., Morrison, R., Hayes, J., Finley, S., Friedl, K., Fleischman, D., Arfanakis, K., James, O., Massoglia, D., Fruehling, J. J., Harding, S., Peskind, E. R., Petrie, E. C., Li, G., Yesavage, J. A., Taylor, J. L., Furst, A. J. & Alzheimer's Disease Neuroimaging Initiative May 19 2015 In : Nature Communications. 6, 6760

Research output: Contribution to journalArticle

Ferritins
Cerebrospinal Fluid
Alzheimer Disease
Iron
Supravalvular Aortic Stenosis
2 Citations

Fifty years of disconnexion syndromes and the Geschwind legacy

Mesulam, M. M. Sep 1 2015 In : Brain. 138, 9, p. 2791-2799 9 p.

Research output: Contribution to journalArticle

Syndrome
Brain Diseases
Neurology
Monographs
Connectivity
17 Citations

FUS Interacts with HSP60 to Promote Mitochondrial Damage

Deng, J., Yang, M., Chen, Y., Chen, X., Liu, J., Sun, S., Cheng, H., Li, Y., Bigio, E. H., Mesulam, M., Xu, Q., Du, S., Fushimi, K., Zhu, L. & Wu, J. Y. 2015 In : PLoS Genetics. 11, 9, e1005357

Research output: Contribution to journalArticle

nuclear proteins
Frontotemporal Lobar Degeneration
defect
damage
Nuclear Proteins
6 Citations

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Mukherjee, S. , Walter, S. , Kauwe, J. S. K. , Saykin, A. J. , Bennett, D. A. , Larson, E. B. , Crane, P. K. , Glymour, M. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Asthana, S. , Atwood, C. S. , Baldwin, C. T. , Barber, R. C. , Barmada, M. M. , Barnes, L. L. , Beach, T. G. , Becker, J. T. & 161 others Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Farrer, L. A., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Haines, J. L., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Kukull, W. A., Kunkle, B. W., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., Mayeux, R., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Pericak-Vance, M. A., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Sano, M., Schellenberg, G. D., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E., Yu, L., Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium Dec 1 2015 In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Alzheimer Disease
Body Mass Index
Phenotype
Odds Ratio
4 Citations

Hippocampal subfield surface deformity in nonsemantic primary progressive aphasia

Christensen, A., Alpert, K., Rogalski, E., Cobia, D., Rao, J., Beg, M. F., Weintraub, S., Mesulam, M. M. & Wang, L. 2015 In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Hippocampus
Dentate Gyrus
Alzheimer Disease
Magnetic Resonance Spectroscopy

Introduction to systems

Mesulam, M. Feb 14 2015 Anatomy and Physiology, Systems. Elsevier Inc., Vol. 2, p. 439 1 p.

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

5 Citations

Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease

Ahmadian, S. S., Rezvanian, A., Peterson, M., Weintraub, S., Bigio, E. H., Mesulam, M. M. & Geula, C. Dec 1 2015 In : Neurobiology of Aging. 36, 12, p. 3163-3170 8 p.

Research output: Contribution to journalArticle

Calbindins
Cholinergic Neurons
Alzheimer Disease
Pathology
Basal Forebrain
18 Citations

Memory improvement via slow-oscillatory stimulation during sleep in older adults

Westerberg, C. E., Florczak, S. M., Weintraub, S., Mesulam, M. M., Marshall, L., Zee, P. C. & Paller, K. A. Sep 1 2015 In : Neurobiology of Aging. 36, 9, p. 2577-2586 10 p.

Research output: Contribution to journalArticle

Sleep
Long-Term Memory
Memory Disorders
Cross-Over Studies
Young Adult
14 Citations

Morphometric and Histologic Substrates of Cingulate Integrity in Elders with Exceptional Memory Capacity

Gefen, T., Gefen, T., Peterson, M., Papastefan, S. T., Martersteck, A., Whitney, K., Rademaker, A., Rademaker, A., Bigio, E. H., Bigio, E. H., Weintraub, S., Weintraub, S., Rogalski, E., Mesulam, M. M., Mesulam, M. M. & Geula, C. Jan 28 2015 In : Journal of Neuroscience. 35, 4, p. 1781-1791 11 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Neurons
Neurofibrillary Tangles
Mild Cognitive Impairment
Episodic Memory
13 Citations

Rarity of the alzheimer disease-protective APP A673T variant in the United States

Wang, L. S. , Naj, A. C. , Graham, R. R. , Crane, P. K. , Kunkle, B. W. , Cruchaga, C. , Gonzalez Murcia, J. D. , Cannon-Albright, L. , Baldwin, C. T. , Zetterberg, H. , Blennow, K. , Kukull, W. A. , Faber, K. M. , Schupf, N. , Norton, M. C. , Tschanz, J. A. T. , Munger, R. G. , Corcoran, C. D. , Rogaeva, E. , Albert, M. S. & 159 others Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Growdon, J. H., Hamilton, R. L., Hamilton-Nelson, K. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M. M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Olichney, J. M., Parisi, J. E., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E., Yu, L., Lin, C. F., Dombroski, B. A., Cantwell, L. B., Partch, A., Valladares, O., Hakonarson, H., St George-Hyslop, P., Green, R. C., Goate, A. M., Foroud, T. M., Carney, R. M., Larson, E. B., Behrens, T. W., Kauwe, J. S. K., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Mayeux, R., Schellenberg, G. D., National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study & Alzheimer's Disease Genetics Consortium Feb 1 2015 In : JAMA Neurology. 72, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Genes
Sweden
Alanine
4 Citations

The CARE Pathway Model for Dementia: Psychosocial and Rehabilitative Strategies for Care in Young-Onset Dementias

Morhardt, D., Weintraub, S., Khayum, B., Robinson, J., Medina, J., O'Hara, M., Mesulam, M. & Rogalski, E. J. Jun 1 2015 In : Psychiatric Clinics of North America. 38, 2, p. 333-352 20 p.

Research output: Contribution to journalReview article

Dementia
Patient Care Planning
Behavioral Symptoms
Caregivers
Quality of Life
4 Citations

The special topics section of Alzheimer's & dementia

Khachaturian, Z. S., Mesulam, M. M., Khachaturian, A. S. & Mohs, R. C. Nov 1 2015 In : Alzheimer's and Dementia. 11, 11, p. 1261-1264 4 p.

Research output: Contribution to journalEditorial

Dementia
19 Citations
Sentence comprehension
Primary Progressive Aphasia
Anatomy
Impairment
Wernicke's area
2 Citations

What do pauses in narrative production reveal about the nature of word retrieval deficits in PPA?

Mack, J. E., Chandler, S. D., Meltzer-Asscher, A., Rogalski, E., Weintraub, S., Mesulam, M. M. & Thompson, C. K. Oct 1 2015 In : Neuropsychologia. 77, p. 211-222 12 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Atrophy
Parietal Lobe
Articulation Disorders
Frontal Lobe
2014
26 Citations

2014 Report on the milestones for the us national plan to address Alzheimer's disease

Fargo, K. N. , Aisen, P. , Albert, M. , Au, R. , Corrada, M. M. , Dekosky, S. , Drachman, D. , Fillit, H. , Gitlin, L. , Haas, M. , Herrup, K. , Kawas, C. , Khachaturian, A. S. , Khachaturian, Z. S. , Klunk, W. , Knopman, D. , Kukull, W. A. , Lamb, B. , Logsdon, R. G. , Maruff, P. & 20 others Mesulam, M., Mobley, W., Mohs, R., Morgan, D., Nixon, R. A., Paul, S., Petersen, R., Plassman, B., Potter, W., Reiman, E., Reisberg, B., Sano, M., Schindler, R., Schneider, L. S., Snyder, P. J., Sperling, R. A., Yaffe, K., Bain, L. J., Thies, W. H. & Carrillo, M. C. Oct 1 2014 In : Alzheimer's and Dementia. 10, 5, p. S430-S452

Research output: Contribution to journalReview article

Alzheimer Disease
Health Services
United States Dept. of Health and Human Services
Developed Countries
11 Citations

A designated odor-language integration system in the human brain

Olofsson, J. K., Hurley, R. S., Bowman, N. E., Bao, X., Mesulam, M. M. & Gottfried, J. A. Nov 5 2014 In : Journal of Neuroscience. 34, 45, p. 14864-14873 10 p.

Research output: Contribution to journalArticle

Systems Integration
Odors
Cues
Brain
Magnetic Resonance Imaging
3 Citations

Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration

Bit-Ivan, E. N., Lee, K. H., Gitelman, D., Weintraub, S., Mesulam, M., Rademakers, R., Isaacs, A. M., Hatanpaa, K. J., White, C. L., Mao, Q., Akman, O., Dimauro, S. & Bigio, E. H. Oct 1 2014 In : Neuropathology and Applied Neurobiology. 40, 6, p. 778-782 5 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Haploinsufficiency
8 Citations

Alterations of Ca2+-responsive proteins within cholinergic neurons in aging and Alzheimer's disease

Riascos, D., Nicholas, A., Samaeekia, R., Yukhananov, R., Mesulam, M. M., Bigio, E. H., Weintraub, S., Guo, L. & Geula, C. Jun 2014 In : Neurobiology of Aging. 35, 6, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

Cholinergic Neurons
Alzheimer Disease
Proteins
Basal Forebrain
Calcium-Calmodulin-Dependent Protein Kinase Type 1
14 Citations

An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution

Zhu, L., Xu, M., Yang, M., Yang, Y., Li, Y., Deng, J., Ruan, L., Liu, J., Du, S., Liu, X., Feng, W., Fushimi, K., Bigio, E. H., Mesulam, M., Wang, C. & Wu, J. Y. Dec 20 2014 In : Human molecular genetics. 23, 25, p. 6863-6877 15 p.

Research output: Contribution to journalArticle

Peptides
TDP-43 Proteinopathies
Amyloid
Amyloidogenic Proteins
Frontotemporal Dementia
1 Citations

A novel GRN mutation (GRN c.708+6-+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: Clinicopathologic report of 6 cases

Bit-Ivan, E. N., Suh, E., Shim, H. S., Weintraub, S., Hyman, B. T., Arnold, S. E., McCarty-Wood, E., Van Deerlin, V. M., Schneider, J. A., Trojanowski, J. Q., Frosch, M. P., Baker, M. C., Rademakers, R., Mesulam, M. & Bigio, E. H. 2014 In : Journal of Neuropathology and Experimental Neurology. 73, 5, p. 467-473 7 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
DNA-Binding Proteins
Mutation
Genes
Frontotemporal Dementia