Marek-Marsel Mesulam

  • 62618 Citations
1972 …2018
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Research Output 1972 2018

2018
1 Citations

A nonverbal route to conceptual knowledge involving the right anterior temporal lobe

Hurley, R. S., Mesulam, M. M., Sridhar, J., Rogalski, E. J. & Thompson, C. K., Aug 1 2018, In : Neuropsychologia. 117, p. 92-101 10 p.

Research output: Contribution to journalArticle

Temporal Lobe
Primary Progressive Aphasia
Atrophy
Language Tests
Semantics

Associations of MAP2K3 gene variants with superior memory in SuperAgers

for the Alzheimer's Disease Neuroimaging Initiative, May 29 2018, In : Frontiers in Aging Neuroscience. 10, MAY, 155

Research output: Contribution to journalArticle

Alzheimer Disease
Neuroimaging
Introns
MAP Kinase Kinase 3
Genes
Primary Progressive Aphasia
DNA-Binding Proteins
Atrophy
Microglia
Phenotype
3 Citations

Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first 10 cases

Rogalski, E., Gefen, T., Mao, Q., Connelly, M., Weintraub, S., Geula, C., Bigio, E. H. & Mesulam, M. M., Jan 1 2018, (Accepted/In press) In : Hippocampus.

Research output: Contribution to journalArticle

Episodic Memory
Personality
Autopsy
Entorhinal Cortex
Neocortex

Combined pathologies in FTLD-TDP types A and C

Gefen, T., Ahmadian, S. S., Mao, Q., Kim, G., Seckin, M., Bonakdarpour, B., Ramos, E. M., Coppola, G., Rademakers, R., Rogalski, E., Rademaker, A., Weintraub, S., Mesulam, M. M., Geula, C. & Bigio, E. H., May 1 2018, In : Journal of Neuropathology and Experimental Neurology. 77, 5, p. 405-412 8 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Pathology
Frontotemporal Lobar Degeneration
Primary Progressive Aphasia
Mutation

Differential neurotoxicity related to tetracycline transactivator and TDP-43 expression in conditional TDP-43 mouse model of frontotemporal lobar degeneration

Kukreja, L., Shahidehpour, R., Kim, G., Keegan, J., Sadleir, K. R., Russell, T., Csernansky, J., Mesulam, M., Vassar, R. J., Wang, L., Dong, H. & Geula, C., Jul 4 2018, In : Journal of Neuroscience. 38, 27, p. 6045-6062 18 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Trans-Activators
DNA-Binding Proteins
Tetracycline
Atrophy
1 Citations

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

Pottier, C. , Zhou, X. , Perkerson, R. B. , Baker, M. , Jenkins, G. D. , Serie, D. J. , Ghidoni, R. , Benussi, L. , Binetti, G. , López de Munain, A. , Zulaica, M. , Moreno, F. , Le Ber, I. , Pasquier, F. , Hannequin, D. , Sánchez-Valle, R. , Antonell, A. , Lladó, A. , Parsons, T. M. , Finch, N. C. A. & 113 others Finger, E. C., Lippa, C. F., Huey, E. D., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Rissman, R. A., Slawek, J., Sitek, E., Johannsen, P., Nielsen, J. E., Ren, Y., van Blitterswijk, M., DeJesus-Hernandez, M., Christopher, E., Murray, M. E., Bieniek, K. F., Evers, B. M., Ferrari, C., Rollinson, S., Richardson, A., Scarpini, E., Fumagalli, G. G., Padovani, A., Hardy, J., Momeni, P., Ferrari, R., Frangipane, F., Maletta, R., Anfossi, M., Gallo, M., Petrucelli, L., Suh, E. R., Lopez, O. L., Wong, T. H., van Rooij, J. G. J., Seelaar, H., Mead, S., Caselli, R. J., Reiman, E. M., Noel Sabbagh, M., Kjolby, M., Nykjaer, A., Karydas, A. M., Boxer, A. L., Grinberg, L. T., Grafman, J., Spina, S., Oblak, A., Mesulam, M. M., Weintraub, S., Geula, C., Hodges, J. R., Piguet, O., Brooks, W. S., Irwin, D. J., Trojanowski, J. Q., Lee, E. B., Josephs, K. A., Parisi, J. E., Ertekin-Taner, N., Knopman, D. S., Nacmias, B., Piaceri, I., Bagnoli, S., Sorbi, S., Gearing, M., Glass, J., Beach, T. G., Black, S. E., Masellis, M., Rogaeva, E., Vonsattel, J. P., Honig, L. S., Kofler, J., Bruni, A. C., Snowden, J., Mann, D., Pickering-Brown, S., Diehl-Schmid, J., Winkelmann, J., Galimberti, D., Graff, C., Öijerstedt, L., Troakes, C., Al-Sarraj, S., Cruchaga, C., Cairns, N. J., Rohrer, J. D., Halliday, G. M., Kwok, J. B., van Swieten, J. C., White, C. L., Ghetti, B., Murell, J. R., Mackenzie, I. R. A., Hsiung, G. Y. R., Borroni, B., Rossi, G., Tagliavini, F., Wszolek, Z. K., Petersen, R. C., Bigio, E. H., Grossman, M., Van Deerlin, V. M., Seeley, W. W., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jun 1 2018, In : The Lancet Neurology. 17, 6, p. 548-558 11 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Inborn Genetic Diseases
Genome-Wide Association Study
Age of Onset
Meta-Analysis
Primary Progressive Aphasia
Microglia
Atrophy
Language
Frontotemporal Lobar Degeneration

Semantic Typicality Effects in Primary Progressive Aphasia

Riley, E. A., Barbieri, E., Weintraub, S., Mesulam, M. M. & Thompson, C. K., Aug 1 2018, In : American Journal of Alzheimer's Disease and Other Dementias. 33, 5, p. 292-300 9 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Aphasia
Semantics
Dementia
Neurodegenerative Diseases
4 Citations

The cholinergic system in the pathophysiology and treatment of Alzheimer's disease

Hampel, H., Mesulam, M. M., Cuello, A. C., Farlow, M. R., Giacobini, E., Grossberg, G. T., Khachaturian, A. S., Vergallo, A., Cavedo, E., Snyder, P. J. & Khachaturian, Z. S., Jul 1 2018, In : Brain. 141, 7, p. 1917-1933 17 p.

Research output: Contribution to journalReview article

Cholinergic Agents
Alzheimer Disease
Therapeutics
Brain
Synapses
1 Citations

Von Economo neurons of the anterior cingulate across the lifespan and in Alzheimer's disease

Gefen, T., Papastefan, S. T., Rezvanian, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M. M. & Geula, C., Feb 1 2018, In : Cortex. 99, p. 69-77 9 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Alzheimer Disease
Neurons
Neurofibrillary Tangles
Aptitude
2017
19 Citations

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A. , Lee, S. E. , Wojta, K. , Ramos, E. M. , Klein, E. , Chen, J. , Boxer, A. L. , Gorno-Tempini, M. L. , Geschwind, D. H. , Schlotawa, L. , Ogryzko, N. V. , Bigio, E. H. , Rogalski, E. , Weintraub, S. , Mesulam, M. M. , Fleming, A. , Coppola, G. , Miller, B. L. , Rubinsztein, D. C. , Agosta, F. & 31 others Alberici, A., Babacan-Yildiz, G., Bennett, D. A., Bilguvar, K., Borroni, B., Caglayan, A. O., Combarros, O., Comi, G., Cortés, E. P., Ferrer, I., Genç, Ş., Gunel, M., Gylys, K. H., Indakoetxea, B., Karageorgiou, C. E., Karydas, A., Kilic, U., De Munain, A. L., Magnani, G., Mahley, R. W., Boneschi, F. M., Martinez, J., Mazzeo, S., Moreno, F., Padovani, A., Papatriantafyllou, J., Rogaeva, E., Sanchez-Juan, P., Santangelo, R., Small, G. W. & Tauopathy Genetics Consortium, Apr 1 2017, In : Brain. 140, 4, p. 1128-1146 19 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Autophagy
Zebrafish
Alleles
Proteasome Endopeptidase Complex
7 Citations

Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS

Genç, B., Jara, J. H., Lagrimas, A. K. B., Pytel, P., Roos, R. P., Mesulam, M. M., Geula, C., Bigio, E. H. & Özdinler, P. H., Feb 6 2017, In : Scientific Reports. 7, 41765

Research output: Contribution to journalArticle

Dendrites
Pathology
Motor Cortex
Alzheimer Disease
Frontotemporal Dementia
47 Citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Mattsson, N. , Andreasson, U. , Zetterberg, H. , Blennow, K. , Weiner, M. W. , Aisen, P. , Toga, A. W. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Shaw, L. M. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Khachaturian, Z. , Sorensen, G. , Carrillo, M. , Kuller, L. & 31 others Raichle, M., Holtzman, D., Paul, S., Davies, P., Fillit, H., Hefti, F., Mesulam, M. M., Potter, W., Snyder, P., Lilly, E., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Rogalski, E., Weintraub, S., Bonakdarpour, B. & Alzheimer's Disease Neuroimaging Initiative, May 1 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Alzheimer Disease
Light
Biomarkers
Cerebrospinal Fluid

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features

Singanamalli, A. , Wang, H. , Madabhushi, A. , Weiner, M. , Aisen, P. , Petersen, R. , Jack, C. , Jagust, W. , Trojanowki, J. , Toga, A. , Beckett, L. , Green, R. , Saykin, A. , Morris, J. , Shaw, L. , Kaye, J. , Quinn, J. , Silbert, L. , Lind, B. , Carter, R. & 221 others Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Marie Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Lynn Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Robbartha, Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific Reports. 7, 1, 8137

Research output: Contribution to journalArticle

Early Diagnosis
Alzheimer Disease
Area Under Curve
Neuroimaging
Proteomics
3 Citations

Case 1-2017: A 70-year-old woman with gradually progressive loss of language

Mesulam, M. M., Dickerson, B. C., Sherman, J. C., Hochberg, D., Gonzalez, R. G., Johnson, K. A. & Frosch, M. P., Jan 12 2017, In : New England Journal of Medicine. 376, 2, p. 158-167 10 p.

Research output: Contribution to journalArticle

2 Citations

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia

Oboudiyat, C., Gefen, T., Varelas, E., Weintraub, S., Rogalski, E., Bigio, E. H. & Mesulam, M. M., May 1 2017, In : Alzheimer's and Dementia. 13, 5, p. 598-601 4 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Dementia
Alzheimer Disease
Pathology
Biomarkers
1 Citations

Disease and region specificity of granulin immunopositivities in Alzheimer disease and frontotemporal lobar degeneration

Mao, Q., Wang, D., Li, Y., Kohler, M., Wilson, J., Parton, Z., Shmaltsuyeva, B., Gursel, D., Rademakers, R., Weintraub, S., Mesulam, M. M., Xia, H. & Bigio, E. H., Jan 1 2017, In : Journal of Neuropathology and Experimental Neurology. 76, 11, p. 957-968 12 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Alzheimer Disease
TDP-43 Proteinopathies
Microglia
Haploinsufficiency
2 Citations

Evidence for an early innate immune response in the motor cortex of ALS

Jara, J. H., Genç, B., Stanford, M. J., Pytel, P., Roos, R. P., Weintraub, S., Mesulam, M. M., Bigio, E. H., Miller, R. J. & Özdinler, P. H., Jun 26 2017, In : Journal of Neuroinflammation. 14, 1, 129

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Motor Cortex
Chemokine CCL2
CCR2 Receptors
Innate Immunity
4 Citations

Functional Connectivity is Reduced in Early-stage Primary Progressive Aphasia When Atrophy is not Prominent

Bonakdarpour, B., Rogalski, E. J., Wang, A., Sridhar, J., Mesulam, M. M. & Hurley, R. S., May 1 2017, In : Alzheimer Disease and Associated Disorders. 31, 2, p. 101-106 6 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Atrophy
Language
Broca Aphasia
Neurodegenerative Diseases
18 Citations

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis

Ward, M. E. , Chen, R. , Huang, H. Y. , Ludwig, C. , Telpoukhovskaia, M. , Taubes, A. , Boudin, H. , Minami, S. S. , Reichert, M. , Albrecht, P. , Gelfand, J. M. , Cruz-Herranz, A. , Cordano, C. , Alavi, M. V. , Leslie, S. , Seeley, W. W. , Miller, B. L. , Bigio, E. , Mesulam, M. M. , Bogyo, M. S. & 6 others Mackenzie, I. R., Staropoli, J. F., Cotman, S. L., Huang, E. J., Gan, L. & Green, A. J., Apr 12 2017, In : Science translational medicine. 9, 385, eaah5642

Research output: Contribution to journalArticle

Neuronal Ceroid-Lipofuscinoses
Haploinsufficiency
Frontotemporal Dementia
Mutation
Lysosomal Storage Diseases
8 Citations

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

Huang, M. , Yang, W. , Feng, Q. , Chen, W. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. C. , Shaw, L. M. , Kaye, J. , Quinn, J. , Silbert, L. , Lind, B. & 219 others Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Jan 12 2017, In : Scientific Reports. 7, 39880

Research output: Contribution to journalArticle

Alzheimer Disease
Cognitive Dysfunction
Brain Diseases
Neuroimaging
Early Diagnosis

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L. , Liu, K. , Yao, X. , Yan, J. , Risacher, S. L. , Han, J. , Guo, L. , Saykin, A. J. , Shen, L. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Morris, J. , Shaw, L. M. & 293 others Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific Reports. 7, 1, 14052

Research output: Contribution to journalArticle

Brain
Imaging techniques
Neuroimaging
Biomarkers
Feature extraction
2 Citations

Psychological well-being in elderly adults with extraordinary episodic memory

Maher, A. C., Kielb, S., Loyer, E., Connelley, M., Rademaker, A., Mesulam, M. M., Weintraub, S., McAdams, D., Logan, R. & Rogalski, E., Oct 1 2017, In : PloS one. 12, 10, e0186413

Research output: Contribution to journalArticle

Episodic Memory
Psychology
Data storage equipment
peers
Neurons
79 Citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R. , Van Der Lee, S. J. , Naj, A. C. , Bellenguez, C. , Badarinarayan, N. , Jakobsdottir, J. , Kunkle, B. W. , Boland, A. , Raybould, R. , Bis, J. C. , Martin, E. R. , Grenier-Boley, B. , Heilmann-Heimbach, S. , Chouraki, V. , Kuzma, A. B. , Sleegers, K. , Vronskaya, M. , Ruiz, A. , Graham, R. R. , Olaso, R. & 429 others Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Jr, W. T. L., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Tsolaki, M., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Goate, A. M., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

Innate Immunity
Gene Frequency
Alzheimer Disease
Odds Ratio
Microglia
3 Citations

Rates of cortical atrophy in adults 80 years and older with superior vs average episodic memory

Cook, A. H., Sridhar, J., Ohm, D., Rademaker, A., Mesulam, M. M., Weintraub, S. & Rogalski, E., Apr 4 2017, In : JAMA - Journal of the American Medical Association. 317, 13, p. 1373-1375 3 p.

Research output: Contribution to journalLetter

Episodic Memory
Cerebral Cortex
Cognition
Atrophy
Longitudinal Studies
1 Citations

Revisiting the cholinergic hypothesis in Alzheimer's disease: Emerging evidence from translational and clinical research

Hampel, H., Mesulam, M. M., Cuello, A. C., Khachaturian, A. S., Farlow, M. R., Snyder, P. J., Giacobini, E. & Khachaturian, Z. S., Jan 1 2017, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Translational Medical Research
Cholinergic Agents
Alzheimer Disease
Cholinesterase Inhibitors
Neuroimaging
2 Citations
Primary Progressive Aphasia
Atrophy
Language
Episodic Memory
Aptitude
52 Citations

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

Mackenzie, I. R. , Nicholson, A. M. , Sarkar, M. , Messing, J. , Purice, M. D. , Pottier, C. , Annu, K. , Baker, M. , Perkerson, R. B. , Kurti, A. , Matchett, B. J. , Mittag, T. , Temirov, J. , Hsiung, G. Y. R. , Krieger, C. , Murray, M. E. , Kato, M. , Fryer, J. D. , Petrucelli, L. , Zinman, L. & 22 others Weintraub, S., Mesulam, M., Keith, J., Zivkovic, S. A., Hirsch-Reinshagen, V., Roos, R. P., Züchner, S., Graff-Radford, N. R., Petersen, R. C., Caselli, R. J., Wszolek, Z. K., Finger, E., Lippa, C., Lacomis, D., Stewart, H., Dickson, D. W., Kim, H. J., Rogaeva, E., Bigio, E., Boylan, K. B., Taylor, J. P. & Rademakers, R., Aug 16 2017, In : Neuron. 95, 4, p. 808-816.e9

Research output: Contribution to journalArticle

Mutation
DNA-Binding Proteins
Hyalin
Phase Transition
Amyotrophic Lateral Sclerosis
11 Citations

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Alzheimer's Disease Genetics Consortium, Jul 1 2017, In : Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Genome
Single Nucleotide Polymorphism
Genome-Wide Association Study
Genetic Loci
2016
19 Citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 1 2016, In : PloS one. 11, 2, e0148717

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer disease
Polymorphism
Gene expression
Alzheimer Disease
55 Citations

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G. , Ibrahim-Verbaas, C. A. , Vronskaya, M. , Lambert, J. C. , Chung, J. , Naj, A. C. , Kunkle, B. W. , Wang, L. S. , Bis, J. C. , Bellenguez, C. , Harold, D. , Lunetta, K. L. , Destefano, A. L. , Grenier-Boley, B. , Sims, R. , Beecham, G. W. , Smith, A. V. , Chouraki, V. , Hamilton-Nelson, K. L. , Ikram, M. A. & 30 others Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C. & Tsolaki, M., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons
9 Citations

Aphasic variant of Alzheimer disease

Rogalski, E., Sridhar, J., Rader, B., Martersteck, A., Chen, K., Cobia, D., Thompson, C. K., Weintraub, S., Bigio, E. H. & Mesulam, M. M., Sep 27 2016, In : Neurology. 87, 13, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Alzheimer Disease
Biomarkers
Atrophy
Language
9 Citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells
45 Citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Risacher, S. L. , McDonald, B. C. , Tallman, E. F. , West, J. D. , Farlow, M. R. , Unverzagt, F. W. , Gao, S. , Boustani, M. , Crane, P. K. , Petersen, R. C. , Jack, C. R. , Jagust, W. J. , Aisen, P. S. , Weiner, M. W. , Saykin, A. J. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Morris, J. & 31 others Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P. J., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Weintraub, S., Bonakdarpour, B., Grafman, J. & Alzheimer's Disease Neuroimaging Initiative, Jun 1 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Cognition
Atrophy
Brain
Neuroimaging
6 Citations

Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions

Kim, G., Ahmadian, S. S., Peterson, M., Parton, Z., Memon, R., Weintraub, S., Rademaker, A., Bigio, E., Mesulam, M. M. & Geula, C., Feb 16 2016, In : Neurology. 86, 7, p. 627-636 10 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Microglia
DNA-Binding Proteins
Pathology
Mutation
3 Citations

Communication Bridge: A pilot feasibility study of Internet-based speech-language therapy for individuals with progressive aphasia

Rogalski, E. J., Saxon, M., McKenna, H., Wieneke, C., Rademaker, A., Corden, M. E., Borio, K., Mesulam, M. M. & Khayum, B., Nov 1 2016, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 4, p. 213-221 9 p.

Research output: Contribution to journalArticle

Language Therapy
Speech Therapy
Aphasia
Feasibility Studies
Internet
107 Citations

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

Iturria-Medina, Y. , Sotero, R. C. , Toussaint, P. J. , Mateos-Pérez, J. M. , Evans, A. C. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Shaw, L. M. , Khachaturian, Z. , Sorensen, G. , Kuller, L. & 31 others Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Mesulam, M. M., Grafman, J. & The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934

Research output: Contribution to journalArticle

Blood Vessels
Alzheimer Disease
Biomarkers
biomarkers
Disease Progression

Eye movements as probes of lexico-semantic processing in a patient with primary progressive aphasia

Seckin, M., Mesulam, M. M., Rademaker, A. W., Voss, J. L., Weintraub, S., Rogalski, E. J. & Hurley, R. S., Jan 2 2016, In : Neurocase. 22, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Eye Movements
Semantics
Dyskinesias
Names
8 Citations

Frontotemporal networks and behavioral symptoms in primary progressive aphasia

D'Anna, L., Mesulam, M. M., Thiebaut De Schotten, M., Dell'Acqua, F., Murphy, D., Wieneke, C., Martersteck, A., Cobia, D., Rogalski, E. & Catani, M., Apr 12 2016, In : Neurology. 86, 15, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Behavioral Symptoms
Temporal Lobe
Diffusion Tensor Imaging
Frontal Lobe
8 Citations

Is in vivo amyloid distribution asymmetric in primary progressive aphasia?

Martersteck, A., Murphy, C., Rademaker, A., Wieneke, C., Weintraub, S., Chen, K., Mesulam, M. M. & Rogalski, E., Mar 1 2016, In : Annals of Neurology. 79, 3, p. 496-501 6 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Amyloid
Parietal Lobe
Positron-Emission Tomography
Dementia
4 Citations

Neuropathologic associations of learning and memory in primary progressive aphasia

Kielb, S., Cook, A., Wieneke, C., Rademaker, A., Bigio, E. H., Mesulam, M. M., Rogalski, E. & Weintraub, S., Jul 1 2016, In : JAMA Neurology. 73, 7, p. 846-852 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Association Learning
Frontotemporal Lobar Degeneration
Alzheimer Disease
Autopsy
8 Citations

Neuropathology of autosomal dominant Alzheimer disease in the national Alzheimer coordinating center database

Ringman, J. M., Monsell, S., Ng, D. W., Zhou, Y., Nguyen, A., Coppola, G., Van Berlo, V., Mendez, M. F., Tung, S., Weintraub, S., Mesulam, M. M., Bigio, E. H., Gitelman, D. R., Fisher-Hubbard, A. O., Albin, R. L. & Vinters, H. V., Jan 1 2016, In : Journal of Neuropathology and Experimental Neurology. 75, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

Cerebral Amyloid Angiopathy
Alzheimer Disease
Lewy Bodies
Databases
Mutation
1 Citations

Postmortem Adult Human Microglia Proliferate in Culture to High Passage and Maintain Their Response to Amyloid-β

Guo, L., Rezvanian, A., Kukreja, L., Hoveydai, R., Bigio, E. H., Mesulam, M. M., El Khoury, J. & Geula, C., Jan 1 2016, In : Journal of Alzheimer's Disease. 54, 3, p. 1157-1167 11 p.

Research output: Contribution to journalArticle

Microglia
Amyloid
Brain
Primates
Rodentia
120 Citations

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H. , Zhang, J. , Makinson, S. R. , Cahill, M. K. , Kelley, K. W. , Huang, H. Y. , Shang, Y. , Oldham, M. C. , Martens, L. H. , Gao, F. , Coppola, G. , Sloan, S. A. , Hsieh, C. L. , Kim, C. C. , Bigio, E. H. , Weintraub, S. , Mesulam, M. M. , Rademakers, R. , MacKenzie, I. R. , Seeley, W. W. & 8 others Karydas, A., Miller, B. L., Borroni, B., Ghidoni, R., Farese, R. V., Paz, J. T., Barres, B. A. & Huang, E. J., May 5 2016, In : Cell. 165, 4, p. 921-935 15 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Complement Activation
Microglia
Chemical activation
Networks (circuits)
3 Citations

Proof of concept demonstration of optimal composite MRI endpoints for clinical trials

Edland, S. D., Ard, M. C., Sridhar, J., Cobia, D., Martersteck, A., Mesulam, M. M. & Rogalski, E. J., Sep 1 2016, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 3, p. 177-181 5 p.

Research output: Contribution to journalArticle

Atrophy
Primary Progressive Aphasia
Clinical Trials
Temporal Lobe
Sample Size
2 Citations

Toward a consensus recommendation for defining the asymptomatic-preclinical phases of putative Alzheimer's disease?

Khachaturian, Z. S., Mesulam, M. M., Mohs, R. C. & Khachaturian, A. S., Mar 1 2016, In : Alzheimer's and Dementia. 12, 3, p. 213-215 3 p.

Research output: Contribution to journalEditorial

Consensus
Alzheimer Disease
2015
11 Citations

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M. , Reitz, C. , Cheng, R. , Vardarajan, B. N. , Jun, G. , Sato, C. , Naj, A. , Rajbhandary, R. , Wang, L. S. , Valladares, O. , Lin, C. F. , Larson, E. B. , Graff-Radford, N. R. , Evans, D. , De Jager, P. L. , Crane, P. K. , Buxbaum, J. D. , Murrell, J. R. , Raj, T. , Ertekin-Taner, N. & 153 others Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 1 2015, In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Single Nucleotide Polymorphism
Consensus
Dementia
39 Citations

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS Medicine. 12, 6, e1001841

Research output: Contribution to journalArticle

Random Allocation
Single Nucleotide Polymorphism
Alzheimer Disease
Smoking
Odds Ratio
23 Citations

Asymmetric connectivity between the anterior temporal lobe and the language network

Hurley, R. S., Bonakdarpour, B., Wang, X. & Mesulam, M. M., Mar 2 2015, In : Journal of Cognitive Neuroscience. 27, 3, p. 464-473 10 p.

Research output: Contribution to journalArticle

Temporal Lobe
Language
language
social cognition
asymmetry