Marek-Marsel Mesulam

  • 60435 Citations
1972 …2018

Research Output 1972 2018

2018
1 Citations
Episodic Memory
Personality
Autopsy
Entorhinal Cortex
Neocortex

Semantic Typicality Effects in Primary Progressive Aphasia

Riley, E. A., Barbieri, E., Weintraub, S., Mesulam, M. M. & Thompson, C. K. Jan 1 2018 (Accepted/In press) In : American Journal of Alzheimer's Disease and other Dementias.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Aphasia
Semantics
Dementia
Neurodegenerative Diseases

Von Economo neurons of the anterior cingulate across the lifespan and in Alzheimer's disease

Gefen, T., Papastefan, S. T., Rezvanian, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M. M. & Geula, C. Feb 1 2018 In : Cortex. 99, p. 69-77 9 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Alzheimer Disease
Neurons
Neurofibrillary Tangles
Aptitude
2017
7 Citations

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A. , Lee, S. E. , Wojta, K. , Ramos, E. M. , Klein, E. , Chen, J. , Boxer, A. L. , Gorno-Tempini, M. L. , Geschwind, D. H. , Schlotawa, L. , Ogryzko, N. V. , Bigio, E. H. , Rogalski, E. , Weintraub, S. , Mesulam, M. M. , Fleming, A. , Coppola, G. , Miller, B. L. , Rubinsztein, D. C. , Agosta, F. & 31 others Alberici, A., Babacan-Yildiz, G., Bennett, D. A., Bilguvar, K., Borroni, B., Caglayan, A. O., Combarros, O., Comi, G., Cortés, E. P., Ferrer, I., Genç, Ş., Gunel, M., Gylys, K. H., Indakoetxea, B., Karageorgiou, C. E., Karydas, A., Kilic, U., De Munain, A. L., Magnani, G., Mahley, R. W., Boneschi, F. M., Martinez, J., Mazzeo, S., Moreno, F., Padovani, A., Papatriantafyllou, J., Rogaeva, E., Sanchez-Juan, P., Santangelo, R., Small, G. W. & Tauopathy Genetics Consortium Apr 1 2017 In : Brain. 140, 4, p. 1128-1146 19 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Autophagy
Zebrafish
Alleles
Proteasome Endopeptidase Complex
6 Citations

Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS

Genç, B., Jara, J. H., Lagrimas, A. K. B., Pytel, P., Roos, R. P., Mesulam, M. M., Geula, C., Bigio, E. H. & Özdinler, P. H. Feb 6 2017 In : Scientific Reports. 7, 41765

Research output: Contribution to journalArticle

Dendrites
Pathology
Motor Cortex
Alzheimer Disease
Frontotemporal Dementia
29 Citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Mattsson, N. , Andreasson, U. , Zetterberg, H. , Blennow, K. , Weiner, M. W. , Aisen, P. , Toga, A. W. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Shaw, L. M. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Khachaturian, Z. , Sorensen, G. , Carrillo, M. , Kuller, L. & 31 others Raichle, M., Holtzman, D., Paul, S., Davies, P., Fillit, H., Hefti, F., Mesulam, M. M., Potter, W., Snyder, P., Lilly, E., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Rogalski, E., Weintraub, S., Bonakdarpour, B. & Alzheimer's Disease Neuroimaging Initiative May 1 2017 In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Alzheimer Disease
Light
Biomarkers
Cerebrospinal Fluid

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features

Singanamalli, A. , Wang, H. , Madabhushi, A. , Weiner, M. , Aisen, P. , Petersen, R. , Jack, C. , Jagust, W. , Trojanowki, J. , Toga, A. , Beckett, L. , Green, R. , Saykin, A. , Morris, J. , Shaw, L. , Kaye, J. , Quinn, J. , Silbert, L. , Lind, B. , Carter, R. & 221 others Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Marie Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Lynn Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Robbartha, Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K. Dec 1 2017 In : Scientific Reports. 7, 1, 8137

Research output: Contribution to journalArticle

Early Diagnosis
Alzheimer Disease
Area Under Curve
Neuroimaging
Proteomics
2 Citations

Case 1-2017: A 70-year-old woman with gradually progressive loss of language

Mesulam, M. M., Dickerson, B. C., Sherman, J. C., Hochberg, D., Gonzalez, R. G., Johnson, K. A. & Frosch, M. P. Jan 12 2017 In : New England Journal of Medicine. 376, 2, p. 158-167 10 p.

Research output: Contribution to journalArticle

2 Citations

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia

Oboudiyat, C., Gefen, T., Varelas, E., Weintraub, S., Rogalski, E., Bigio, E. H. & Mesulam, M. M. May 1 2017 In : Alzheimer's and Dementia. 13, 5, p. 598-601 4 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Dementia
Alzheimer Disease
Pathology
Biomarkers

Disease and region specificity of granulin immunopositivities in Alzheimer disease and frontotemporal lobar degeneration

Mao, Q., Wang, D., Li, Y., Kohler, M., Wilson, J., Parton, Z., Shmaltsuyeva, B., Gursel, D., Rademakers, R., Weintraub, S., Mesulam, M. M., Xia, H. & Bigio, E. H. Jan 1 2017 In : Journal of Neuropathology and Experimental Neurology. 76, 11, p. 957-968 12 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Alzheimer Disease
TDP-43 Proteinopathies
Microglia
Haploinsufficiency
1 Citations

Evidence for an early innate immune response in the motor cortex of ALS

Jara, J. H., Genç, B., Stanford, M. J., Pytel, P., Roos, R. P., Weintraub, S., Mesulam, M. M., Bigio, E. H., Miller, R. J. & Özdinler, P. H. Jun 26 2017 In : Journal of Neuroinflammation. 14, 1, 129

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Motor Cortex
Chemokine CCL2
CCR2 Receptors
Innate Immunity
1 Citations

Functional Connectivity is Reduced in Early-stage Primary Progressive Aphasia When Atrophy is not Prominent

Bonakdarpour, B., Rogalski, E. J., Wang, A., Sridhar, J., Mesulam, M. M. & Hurley, R. S. May 1 2017 In : Alzheimer Disease and Associated Disorders. 31, 2, p. 101-106 6 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Atrophy
Language
Broca Aphasia
Neurodegenerative Diseases
9 Citations

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis

Ward, M. E. , Chen, R. , Huang, H. Y. , Ludwig, C. , Telpoukhovskaia, M. , Taubes, A. , Boudin, H. , Minami, S. S. , Reichert, M. , Albrecht, P. , Gelfand, J. M. , Cruz-Herranz, A. , Cordano, C. , Alavi, M. V. , Leslie, S. , Seeley, W. W. , Miller, B. L. , Bigio, E. , Mesulam, M. M. , Bogyo, M. S. & 6 others Mackenzie, I. R., Staropoli, J. F., Cotman, S. L., Huang, E. J., Gan, L. & Green, A. J. Apr 12 2017 In : Science Translational Medicine. 9, 385, eaah5642

Research output: Contribution to journalArticle

Neuronal Ceroid-Lipofuscinoses
Haploinsufficiency
Frontotemporal Dementia
Mutation
Lysosomal Storage Diseases
4 Citations

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

Huang, M. , Yang, W. , Feng, Q. , Chen, W. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Shaw, L. M. , Kaye, J. , Quinn, J. , Silbert, L. , Lind, B. & 222 others Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Morris, J. C., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K. Jan 12 2017 In : Scientific Reports. 7, 39880

Research output: Contribution to journalArticle

Alzheimer Disease
Cognitive Dysfunction
Brain Diseases
Neuroimaging
Early Diagnosis

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L. , Liu, K. , Yao, X. , Yan, J. , Risacher, S. L. , Han, J. , Guo, L. , Saykin, A. J. , Shen, L. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Morris, J. , Shaw, L. M. & 293 others Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K. Dec 1 2017 In : Scientific Reports. 7, 1, 14052

Research output: Contribution to journalArticle

Brain
Imaging techniques
Neuroimaging
Biomarkers
Feature extraction

Psychological well-being in elderly adults with extraordinary episodic memory

Maher, A. C., Kielb, S., Loyer, E., Connelley, M., Rademaker, A., Mesulam, M. M., Weintraub, S., McAdams, D., Logan, R. & Rogalski, E. Oct 1 2017 In : PLoS ONE. 12, 10, e0186413

Research output: Contribution to journalArticle

Episodic Memory
Psychology
Data storage equipment
peers
Neurons
39 Citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R. , Van Der Lee, S. J. , Naj, A. C. , Bellenguez, C. , Badarinarayan, N. , Jakobsdottir, J. , Kunkle, B. W. , Boland, A. , Raybould, R. , Bis, J. C. , Martin, E. R. , Grenier-Boley, B. , Heilmann-Heimbach, S. , Chouraki, V. , Kuzma, A. B. , Sleegers, K. , Vronskaya, M. , Ruiz, A. , Graham, R. R. , Olaso, R. & 429 others Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Jr, W. T. L., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Tsolaki, M., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Goate, A. M., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D. Sep 1 2017 In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

Innate Immunity
Gene Frequency
Alzheimer Disease
Odds Ratio
Microglia
2 Citations

Rates of cortical atrophy in adults 80 years and older with superior vs average episodic memory

Cook, A. H., Sridhar, J., Ohm, D., Rademaker, A., Mesulam, M. M., Weintraub, S. & Rogalski, E. Apr 4 2017 In : JAMA - Journal of the American Medical Association. 317, 13, p. 1373-1375 3 p.

Research output: Contribution to journalLetter

Episodic Memory
Cerebral Cortex
Cognition
Atrophy
Longitudinal Studies
1 Citations

Revisiting the cholinergic hypothesis in Alzheimer's disease: Emerging evidence from translational and clinical research

Hampel, H., Mesulam, M. M., Cuello, A. C., Khachaturian, A. S., Farlow, M. R., Snyder, P. J., Giacobini, E. & Khachaturian, Z. S. Jan 1 2017 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Translational Medical Research
Cholinergic Agents
Alzheimer Disease
Cholinesterase Inhibitors
Neuroimaging
Primary Progressive Aphasia
Atrophy
Language
Episodic Memory
Aptitude
24 Citations

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

Mackenzie, I. R. , Nicholson, A. M. , Sarkar, M. , Messing, J. , Purice, M. D. , Pottier, C. , Annu, K. , Baker, M. , Perkerson, R. B. , Kurti, A. , Matchett, B. J. , Mittag, T. , Temirov, J. , Hsiung, G. Y. R. , Krieger, C. , Murray, M. E. , Kato, M. , Fryer, J. D. , Petrucelli, L. , Zinman, L. & 22 others Weintraub, S., Mesulam, M., Keith, J., Zivkovic, S. A., Hirsch-Reinshagen, V., Roos, R. P., Züchner, S., Graff-Radford, N. R., Petersen, R. C., Caselli, R. J., Wszolek, Z. K., Finger, E., Lippa, C., Lacomis, D., Stewart, H., Dickson, D. W., Kim, H. J., Rogaeva, E., Bigio, E., Boylan, K. B., Taylor, J. P. & Rademakers, R. Aug 16 2017 In : Neuron. 95, 4, p. 808-816.e9

Research output: Contribution to journalArticle

Mutation
DNA-Binding Proteins
Hyalin
Phase Transition
Amyotrophic Lateral Sclerosis
6 Citations

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Jun, G. R. , Jun, G. R. , Chung, J. , Logue, M. W. , Sherva, R. , Farrer, L. A. , Mez, J. , Farrer, L. A. , Barber, R. , Beecham, G. W. , Hamilton-Nelson, K. L. , Kunkle, B. W. , Martin, E. R. , Pericak-Vance, M. A. , Bennett, D. A. , Logue, M. W. , Buxbaum, J. D. , Goate, A. M. , Goate, A. , Carlos, M. & 31 others Byrd, G. S., Carrasquillo, M. M., Ertekin-Taner, N., Graff-Radford, N. R., Younkin, S. G., Crane, P. K., Mukherjee, S., Thornton, T., Cruchaga, C., Cruchaga, C., De Jager, P., De Jager, P., Larson, E. B., Evans, D., Fallin, M. D., Foroud, T. M., Friedland, R. P., Hendrie, H., Hendrie, H., Hall, K. S., Hall, K. S., Inzelberg, R., Kamboh, M. I., Kauwe, J. S. K., Kukull, W. A., Kukull, W. A., Kuwano, R., Larson, E. B., Mesulam, M., Weintraub, S. & Alzheimer's Disease Genetics Consortium Jul 1 2017 In : Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Genome
Single Nucleotide Polymorphism
Genome-Wide Association Study
Genetic Loci
2016
14 Citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Karch, C. M. , Ezerskiy, L. A. , Bertelsen, S. , Goate, A. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Baldwin, C. T. , Barber, R. , Barmada, M. M. , Barnes, L. L. , Beach, T. G. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. , Boeve, B. F. & 31 others Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Crane, P. K., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Mesulam, M., Weintraub, S. & Alzheimer's Disease Genetics Consortium (ADGC) Feb 1 2016 In : PLoS ONE. 11, 2, e0148717

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer disease
Polymorphism
Gene expression
Alzheimer Disease
42 Citations

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G. , Ibrahim-Verbaas, C. A. , Vronskaya, M. , Lambert, J. C. , Chung, J. , Naj, A. C. , Kunkle, B. W. , Wang, L. S. , Bis, J. C. , Bellenguez, C. , Harold, D. , Lunetta, K. L. , Destefano, A. L. , Grenier-Boley, B. , Sims, R. , Beecham, G. W. , Smith, A. V. , Chouraki, V. , Hamilton-Nelson, K. L. , Ikram, M. A. & 30 others Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C. & Tsolaki, M. Jan 1 2016 In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons
6 Citations

Aphasic variant of Alzheimer disease

Rogalski, E., Sridhar, J., Rader, B., Martersteck, A., Chen, K., Cobia, D., Thompson, C. K., Weintraub, S., Bigio, E. H. & Mesulam, M. M. Sep 27 2016 In : Neurology. 87, 13, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Alzheimer Disease
Biomarkers
Atrophy
Language
8 Citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Adams, P. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Asthana, S. , Atwood, C. S. , Baldwin, C. T. , Barber, R. C. , Barmada, M. M. , Barnes, L. L. , Barral, S. , Beach, T. G. , Becker, J. T. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. & 31 others Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., David, C. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Mesulam, M., Weintraub, S. & Alzheimer's Disease Genetics Consortium (ADGC) May 1 2016 In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells
32 Citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Risacher, S. L. , McDonald, B. C. , Tallman, E. F. , West, J. D. , Farlow, M. R. , Unverzagt, F. W. , Gao, S. , Boustani, M. , Crane, P. K. , Petersen, R. C. , Jack, C. R. , Jagust, W. J. , Aisen, P. S. , Weiner, M. W. , Saykin, A. J. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Morris, J. & 31 others Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P. J., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Weintraub, S., Bonakdarpour, B., Grafman, J. & Alzheimer's Disease Neuroimaging Initiative Jun 1 2016 In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Cognition
Atrophy
Brain
Neuroimaging
1 Citations

Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions

Kim, G., Ahmadian, S. S., Peterson, M., Parton, Z., Memon, R., Weintraub, S., Rademaker, A., Bigio, E., Mesulam, M. M. & Geula, C. Feb 16 2016 In : Neurology. 86, 7, p. 627-636 10 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Microglia
DNA-Binding Proteins
Pathology
Mutation
1 Citations

Communication Bridge: A pilot feasibility study of Internet-based speech-language therapy for individuals with progressive aphasia

Rogalski, E. J., Saxon, M., McKenna, H., Wieneke, C., Rademaker, A., Corden, M. E., Borio, K., Mesulam, M. M. & Khayum, B. Nov 1 2016 In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 4, p. 213-221 9 p.

Research output: Contribution to journalArticle

Language Therapy
Speech Therapy
Aphasia
Feasibility Studies
Internet
82 Citations

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

Iturria-Medina, Y. , Sotero, R. C. , Toussaint, P. J. , Mateos-Pérez, J. M. , Evans, A. C. , Weiner, M. W. , Aisen, P. , Petersen, R. , Jack, C. R. , Jagust, W. , Trojanowki, J. Q. , Toga, A. W. , Beckett, L. , Green, R. C. , Saykin, A. J. , Morris, J. , Shaw, L. M. , Khachaturian, Z. , Sorensen, G. , Kuller, L. & 31 others Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Mesulam, M. M., Grafman, J. & The Alzheimer's Disease Neuroimaging Initiative Jun 21 2016 In : Nature Communications. 7, 11934

Research output: Contribution to journalArticle

Blood Vessels
Alzheimer Disease
Biomarkers
biomarkers
Disease Progression

Eye movements as probes of lexico-semantic processing in a patient with primary progressive aphasia

Seckin, M., Mesulam, M. M., Rademaker, A. W., Voss, J. L., Weintraub, S., Rogalski, E. J. & Hurley, R. S. Jan 2 2016 In : Neurocase. 22, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Eye Movements
Semantics
Dyskinesias
Names
6 Citations

Frontotemporal networks and behavioral symptoms in primary progressive aphasia

D'Anna, L., Mesulam, M. M., Thiebaut De Schotten, M., Dell'Acqua, F., Murphy, D., Wieneke, C., Martersteck, A., Cobia, D., Rogalski, E. & Catani, M. Apr 12 2016 In : Neurology. 86, 15, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Behavioral Symptoms
Temporal Lobe
Diffusion Tensor Imaging
Frontal Lobe
6 Citations

Is in vivo amyloid distribution asymmetric in primary progressive aphasia?

Martersteck, A., Murphy, C., Rademaker, A., Wieneke, C., Weintraub, S., Chen, K., Mesulam, M. M. & Rogalski, E. Mar 1 2016 In : Annals of Neurology. 79, 3, p. 496-501 6 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Amyloid
Parietal Lobe
Positron-Emission Tomography
Dementia
2 Citations

Neuropathologic associations of learning and memory in primary progressive aphasia

Kielb, S., Cook, A., Wieneke, C., Rademaker, A., Bigio, E. H., Mesulam, M. M., Rogalski, E. & Weintraub, S. Jul 1 2016 In : JAMA Neurology. 73, 7, p. 846-852 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Association Learning
Frontotemporal Lobar Degeneration
Alzheimer Disease
Autopsy
7 Citations

Neuropathology of autosomal dominant Alzheimer disease in the national Alzheimer coordinating center database

Ringman, J. M., Monsell, S., Ng, D. W., Zhou, Y., Nguyen, A., Coppola, G., Van Berlo, V., Mendez, M. F., Tung, S., Weintraub, S., Mesulam, M. M., Bigio, E. H., Gitelman, D. R., Fisher-Hubbard, A. O., Albin, R. L. & Vinters, H. V. Jan 1 2016 In : Journal of Neuropathology and Experimental Neurology. 75, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

Cerebral Amyloid Angiopathy
Alzheimer Disease
Lewy Bodies
Databases
Mutation
1 Citations

Postmortem Adult Human Microglia Proliferate in Culture to High Passage and Maintain Their Response to Amyloid-β

Guo, L., Rezvanian, A., Kukreja, L., Hoveydai, R., Bigio, E. H., Mesulam, M. M., El Khoury, J. & Geula, C. Jan 1 2016 In : Journal of Alzheimer's Disease. 54, 3, p. 1157-1167 11 p.

Research output: Contribution to journalArticle

Microglia
Amyloid
Brain
Primates
Rodentia
93 Citations

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H. , Zhang, J. , Makinson, S. R. , Cahill, M. K. , Kelley, K. W. , Huang, H. Y. , Shang, Y. , Oldham, M. C. , Martens, L. H. , Gao, F. , Coppola, G. , Sloan, S. A. , Hsieh, C. L. , Kim, C. C. , Bigio, E. H. , Weintraub, S. , Mesulam, M. M. , Rademakers, R. , MacKenzie, I. R. , Seeley, W. W. & 8 others Karydas, A., Miller, B. L., Borroni, B., Ghidoni, R., Farese, R. V., Paz, J. T., Barres, B. A. & Huang, E. J. May 5 2016 In : Cell. 165, 4, p. 921-935 15 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Complement Activation
Microglia
Chemical activation
Networks (circuits)
3 Citations

Proof of concept demonstration of optimal composite MRI endpoints for clinical trials

Edland, S. D., Ard, M. C., Sridhar, J., Cobia, D., Martersteck, A., Mesulam, M. M. & Rogalski, E. J. Sep 1 2016 In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 3, p. 177-181 5 p.

Research output: Contribution to journalArticle

Atrophy
Primary Progressive Aphasia
Clinical Trials
Temporal Lobe
Sample Size
2 Citations

Toward a consensus recommendation for defining the asymptomatic-preclinical phases of putative Alzheimer's disease?

Khachaturian, Z. S., Mesulam, M. M., Mohs, R. C. & Khachaturian, A. S. Mar 1 2016 In : Alzheimer's and Dementia. 12, 3, p. 213-215 3 p.

Research output: Contribution to journalEditorial

Consensus
Alzheimer Disease
2015
10 Citations

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M. , Reitz, C. , Cheng, R. , Vardarajan, B. N. , Jun, G. , Sato, C. , Naj, A. , Rajbhandary, R. , Wang, L. S. , Valladares, O. , Lin, C. F. , Larson, E. B. , Graff-Radford, N. R. , Evans, D. , De Jager, P. L. , Crane, P. K. , Buxbaum, J. D. , Murrell, J. R. , Raj, T. , Ertekin-Taner, N. & 30 others Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S. & Albin, R. L. Nov 1 2015 In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Single Nucleotide Polymorphism
Consensus
Dementia
32 Citations

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium Jun 1 2015 In : PLoS Medicine. 12, 6, e1001841

Research output: Contribution to journalArticle

Random Allocation
Single Nucleotide Polymorphism
Alzheimer Disease
Smoking
Odds Ratio
19 Citations

Asymmetric connectivity between the anterior temporal lobe and the language network

Hurley, R. S., Bonakdarpour, B., Wang, X. & Mesulam, M. M. Mar 2 2015 In : Journal of Cognitive Neuroscience. 27, 3, p. 464-473 10 p.

Research output: Contribution to journalArticle

Temporal Lobe
Language
language
social cognition
asymmetry
16 Citations

Benefits of mindfulness training for patients with progressive cognitive decline and their caregivers

Paller, K. A., Creery, J. D., Florczak, S. M., Weintraub, S., Mesulam, M. M., Reber, P. J., Kiragu, J., Rooks, J., Safron, A., Morhardt, D., O'Hara, M., Gigler, K. L., Molony, J. M. & Maslar, M. May 6 2015 In : American Journal of Alzheimer's Disease and Other Dementias. 30, 3, p. 257-267 11 p.

Research output: Contribution to journalArticle

Mindfulness
Caregivers
Neurodegenerative Diseases
Alzheimer Disease
Sleep
2 Citations

Diffuse leukoencephalopathy with spheroids presenting as primary progressive aphasia

Oboudiyat, C., Bigio, E. H., Bonakdarpour, B., Baker, M. C., Rademakers, R., Weintraub, S. & Mesulam, M. M. Jan 1 2015 In : Neurology. 85, 7, p. 652-653 2 p.

Research output: Contribution to journalShort survey

Primary Progressive Aphasia
Memantine
Leukoencephalopathies
Pravastatin
Learning Disorders
57 Citations

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative May 19 2015 In : Nature communications. 6, 6760

Research output: Contribution to journalArticle

cerebrospinal fluid
Cerebrospinal fluid
Ferritins
Cerebrospinal Fluid
Alzheimer Disease
4 Citations

Fifty years of disconnexion syndromes and the Geschwind legacy

Mesulam, M. M. Sep 1 2015 In : Brain. 138, 9, p. 2791-2799 9 p.

Research output: Contribution to journalArticle

Brain Diseases
Neurology
Connectivity
Disruption
Monographs
27 Citations

FUS Interacts with HSP60 to Promote Mitochondrial Damage

Deng, J., Yang, M., Chen, Y., Chen, X., Liu, J., Sun, S., Cheng, H., Li, Y., Bigio, E. H., Mesulam, M., Xu, Q., Du, S., Fushimi, K., Zhu, L. & Wu, J. Y. Jan 1 2015 In : PLoS genetics. 11, 9, e1005357

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
nuclear proteins
defect
Nuclear Proteins
chaperonins
10 Citations

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium Dec 1 2015 In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Alzheimer Disease
Body Mass Index
Phenotype
Odds Ratio
5 Citations

Hippocampal subfield surface deformity in nonsemantic primary progressive aphasia

Christensen, A., Alpert, K., Rogalski, E., Cobia, D., Rao, J., Beg, M. F., Weintraub, S., Mesulam, M. M. & Wang, L. Jan 1 2015 In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Hippocampus
Dentate Gyrus
Alzheimer Disease
Magnetic Resonance Spectroscopy

Introduction to systems

Mesulam, M. Feb 14 2015 Anatomy and Physiology, Systems. Elsevier Inc., Vol. 2, 1 p.

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript