• 67406 Citations
1972 …2023
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Research Output 1972 2019

42 Citations (Scopus)

2014 Report on the milestones for the us national plan to address Alzheimer's disease

Fargo, K. N., Aisen, P., Albert, M., Au, R., Corrada, M. M., Dekosky, S., Drachman, D., Fillit, H., Gitlin, L., Haas, M., Herrup, K., Kawas, C., Khachaturian, A. S., Khachaturian, Z. S., Klunk, W., Knopman, D., Kukull, W. A., Lamb, B., Logsdon, R. G., Maruff, P. & 20 others, Mesulam, M., Mobley, W., Mohs, R., Morgan, D., Nixon, R. A., Paul, S., Petersen, R., Plassman, B., Potter, W., Reiman, E., Reisberg, B., Sano, M., Schindler, R., Schneider, L. S., Snyder, P. J., Sperling, R. A., Yaffe, K., Bain, L. J., Thies, W. H. & Carrillo, M. C., Oct 1 2014, In : Alzheimer's and Dementia. 10, 5, p. S430-S452

Research output: Contribution to journalArticle

Alzheimer Disease
Health Services
United States Dept. of Health and Human Services
Research
Developed Countries
30 Citations (Scopus)

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A., Lee, S. E., Wojta, K., Ramos, E. M., Klein, E., Chen, J., Boxer, A. L., Gorno-Tempini, M. L., Geschwind, D. H., Schlotawa, L., Ogryzko, N. V., Bigio, E. H., Rogalski, E., Weintraub, S., Mesulam, M. M., Fleming, A., Coppola, G., Miller, B. L., Rubinsztein, D. C., Agosta, F. & 31 others, Alberici, A., Babacan-Yildiz, G., Bennett, D. A., Bilguvar, K., Borroni, B., Caglayan, A. O., Combarros, O., Comi, G., Cortés, E. P., Ferrer, I., Genç, Ş., Gunel, M., Gylys, K. H., Indakoetxea, B., Karageorgiou, C. E., Karydas, A., Kilic, U., De Munain, A. L., Magnani, G., Mahley, R. W., Boneschi, F. M., Martinez, J., Mazzeo, S., Moreno, F., Padovani, A., Papatriantafyllou, J., Rogaeva, E., Sanchez-Juan, P., Santangelo, R., Small, G. W. & Tauopathy Genetics Consortium, Apr 1 2017, In : Brain. 140, 4, p. 1128-1146 19 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Autophagy
Zebrafish
Alleles
Proteasome Endopeptidase Complex
3 Citations (Scopus)

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
Cerebrospinal Fluid
Amyloid
Alzheimer Disease
Positron-Emission Tomography
Area Under Curve
3 Citations (Scopus)

Abnormalities in the Brain and Schizophrenia

Crow, T. J., Nasrallah, H. A., Olson, S. C., Coffman, J. A., Schwarzkopf, S. B., Ramirez, P. M., Opler, L. A., Kanofsky, J. D., Sandyk, R., Kay, S. R., Lidz, T., Fleck, S., Weinberger, D. R., Suddath, R. L., Torrey, E. F., Christison, G. W., Casanova, M. F. & Mesulam, M. M., Aug 23 1990, In : New England Journal of Medicine. 323, 8, p. 545-548 4 p.

Research output: Contribution to journalLetter

Schizophrenia
Brain
Lateral Ventricles
Hippocampus

Abnormalities in the brain and schizophrenia (Reply II)

Mesulam, M. M., Jan 1 1990, In : New England Journal of Medicine. 323, 8, 1 p.

Research output: Contribution to journalLetter

Schizophrenia
Brain
85 Citations (Scopus)

Accelerated forgetting in association with temporal lobe epilepsy and paraneoplastic encephalitis

O'Connor, M., Sieggreen, M. A., Ahern, G., Schomer, D. & Mesulam, M., Jan 1 1997, In : Brain and cognition. 35, 1, p. 71-84 14 p.

Research output: Contribution to journalArticle

Temporal Lobe Epilepsy
Encephalitis
Amnesia
Seizures
Paraldehyde
1 Citation (Scopus)

Acetylcholine Neurotransmission in CNS

Mesulam, M-M., Jan 1 2009, Encyclopedia of Neuroscience. Elsevier Ltd., p. 1-4 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Synaptic Transmission
Cholinergic Agents
Acetylcholine
Alzheimer Disease
Basal Nucleus of Meynert
52 Citations (Scopus)

Acetylcholinesterase fiber staining in the human hippocampus and parahippocampal gyrus

Green, R. C. & Mesulam, MM. M., Jan 1 1988, In : Journal of Comparative Neurology. 273, 4, p. 488-499 12 p.

Research output: Contribution to journalArticle

Parahippocampal Gyrus
Acetylcholinesterase
Hippocampus
Staining and Labeling
Dentate Gyrus
420 Citations (Scopus)

Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine

Mesulam, M-M., Guillozet, A., Shaw, P. L., Levey, A., Duysen, E. G. & Lockridge, O., Apr 3 2002, In : Neuroscience. 110, 4, p. 627-639 13 p.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Acetylcholinesterase
Cholinergic Agents
Acetylcholine
Hydrolysis
84 Citations (Scopus)
Cerebral Cortex
Neurons
Pyramidal Cells
Motor Cortex
Acetylcholinesterase
317 Citations (Scopus)

Acetylcholinesterase-rich projections from the basal forebrain of the rhesus monkey to neocortex

Mesulam, M. M. & Van Hoesen, G. W., Jun 4 1976, In : Brain research. 109, 1, p. 152-157 6 p.

Research output: Contribution to journalArticle

Brain Mapping
Neural Pathways
Diencephalon
Telencephalon
Neocortex
25 Citations (Scopus)

Acetylcholinesterase-rich pyramidal neurons in alzheimer's disease

Heckers, S., Geula, C. & Mesulam, M. M., Jan 1 1992, In : Neurobiology of Aging. 13, 4, p. 455-460 6 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Acetylcholinesterase
Alzheimer Disease
Neurons
Motor Cortex
79 Citations (Scopus)
Pyramidal Cells
Neocortex
Hippocampus
Alzheimer Disease
Parturition
54 Citations (Scopus)

A clinical trial of bromocriptine for treatment of primary progressive aphasia [2]

Reed, D. A., Johnson, N. A., Thompson, C. K., Weintraub, S. & Mesulam, M-M., Nov 1 2004, In : Annals of neurology. 56, 5, 1 p.

Research output: Contribution to journalLetter

Drug Dose Response Relationship
Primary Progressive Aphasia
Language Tests
Bromocriptine
Dopamine Agonists
1868 Citations (Scopus)

A cortical network for directed attention and unilateral neglect

Mesulam, M. M., Jan 1 1981, In : Annals of neurology. 10, 4, p. 309-325 17 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Parietal Lobe
Frontal Lobe
Arousal
Haplorhini
38 Citations (Scopus)

A cortical pathway to olfactory naming: Evidence from primary progressive aphasia

Olofsson, J. K., Rogalski, E., Harrison, T., Mesulam, M. M. & Gottfried, J. A., Apr 2013, In : Brain. 136, 4, p. 1245-1259 15 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Olfactory Pathways
Names
Cues
Prefrontal Cortex

Activated microglia in cortical white matter across cognitive aging trajectories

Gefen, T., Kim, G., Bolbolan, K., Geoly, A., Ohm, D., Oboudiyat, C., Shahidehpour, R., Rademaker, A., Weintraub, S., Bigio, E. H., Marsel Mesulam, M., Rogalski, E. & Geula, C., Jan 1 2019, In : Frontiers in Aging Neuroscience. 11, MAY, 094.

Research output: Contribution to journalArticle

Open Access
Microglia
Inflammation Mediators
Gliosis
HLA Antigens
Cognitive Aging
2 Citations (Scopus)

Activation of overlapping but not identical frontal and parietal regions by saccadic eye movement and overt spatial attention tasks

Gitelman, D. R., Nobre, A. C., Kim, Y. H., Parrish, T. B., LaBar, K. S. & Mesulam, M-M., Dec 1 1998, In : NeuroImage. 7, 4 PART II

Research output: Contribution to journalArticle

Parietal Lobe
Saccades
10 Citations (Scopus)

Acute behavioral derangements without hemiplegia in cerebrovascular accidents

Mesulam, M. M., Dec 1 1979, In : Primary Care - Clinics in Office Practice. 6, 4, p. 813-826 14 p.

Research output: Contribution to journalReview article

Mental Processes
Hemiplegia
Coordination Complexes
Language
Stroke
157 Citations (Scopus)

Acute confusional states with right middle cerebral artery infarctions

Mesulam, M. M., Waxman, S. G., Geschwind, N. & Sabin, T. D., Jan 1 1976, In : Journal of Neurology Neurosurgery and Psychiatry. 39, 1, p. 84-89 6 p.

Research output: Contribution to journalArticle

Confusion
Middle Cerebral Artery Infarction
Middle Cerebral Artery
Infarction
Haplorhini
324 Citations (Scopus)

Additional factors influencing sensitivity in the tetramethyl benzidine method for horseradish peroxidase neurohistochemistry

Mesulam, M. M., Hegarty, E., Barbas, H., Carson, K. A., Gower, E. C., Knapp, A. G., Moss, M. B. & Mufson, E. J., Jan 1 1980, In : Unknown Journal. 28, 11, p. 1255-1259 5 p.

Research output: Contribution to journalArticle

Horseradish Peroxidase
Reaction products
Dehydration
Tissue
Wheat Germ Agglutinins
25 Citations (Scopus)

A designated odor-language integration system in the human brain

Olofsson, J. K., Hurley, R. S., Bowman, N. E., Bao, X., Mesulam, M-M. & Gottfried, J. A., Nov 5 2014, In : Journal of Neuroscience. 34, 45, p. 14864-14873 10 p.

Research output: Contribution to journalArticle

Systems Integration
Cues
Language
Brain
Magnetic Resonance Imaging
17 Citations (Scopus)

Adult-Onset Stuttering Treated With Anticonvulsants

Baratz, R. & Mesulam, M. M., Jan 1 1981, In : Archives of Neurology. 38, 2, 1 p.

Research output: Contribution to journalArticle

Stuttering
Anticonvulsants
Aptitude
Aphasia
Electroencephalography
4 Citations (Scopus)

Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration

Bit-Ivan, E. N., Lee, K. H., Gitelman, D., Weintraub, S., Mesulam, M-M., Rademakers, R., Isaacs, A. M., Hatanpaa, K. J., White, C. L., Mao, Q., Akman, O., Dimauro, S. & Bigio, E. H., Oct 1 2014, In : Neuropathology and Applied Neurobiology. 40, 6, p. 778-782 5 p.

Research output: Contribution to journalArticle

Glycogen Debranching Enzyme System
Frontotemporal Lobar Degeneration
Glycogen Storage Disease
Haploinsufficiency
Nervous System Diseases
17 Citations (Scopus)

Afasia Progressiva Primária: Uma Demência Da Rede De Linguagem

Translated title of the contribution: Primary progressive aphasia: A dementia of the language networkMesulam, M-M., Jan 1 2013, In : Dementia e Neuropsychologia. 7, 1, p. 2-9 8 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Dementia
Language
Aphasia
Atrophy
36 Citations (Scopus)

Age-related loss of calbindin from human basal forebrain cholinergic neurons

Wu, C. K., Mesulam, M. M. & Geula, C., Jan 1 1997, In : NeuroReport. 8, 9-10, p. 2209-2213 5 p.

Research output: Contribution to journalArticle

Calbindins
Cholinergic Neurons
Nerve Growth Factor Receptor
Choline O-Acetyltransferase
Neurodegenerative Diseases
82 Citations (Scopus)

Age‐related shrinkage of cortically projecting cholinergic neurons: A selective effect

Mesulam, MM. M., Mufson, E. J. & Rogers, J., Jan 1 1987, In : Annals of Neurology. 22, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

Cholinergic Neurons
Cholinergic Agents
Neurons
Amygdala
Cerebral Cortex
8 Citations (Scopus)

A heteromodal large-scale network for spatial attention

Mesulam, M-M., Small, D. M., Vandenberghe, R., Gitelman, D. R. & Nobre, A. C., Dec 1 2005, Neurobiology of Attention. Elsevier Inc., p. 29-34 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Perceptual Disorders
Gyrus Cinguli
Frontal Lobe
Thalamus
51 Citations (Scopus)
Cholinesterases
Horseradish Peroxidase
Neurons
Olfactory Bulb
Neocortex
535 Citations (Scopus)

A large-scale distributed network for covert spatial attention. Further anatomical delineation based on stringent behavioural and cognitive controls

Gitelman, D. R., Nobre, A. C., Parrish, T. B., LaBar, K. S., Kim, Y. H., Meyer, J. R. & Mesulam, M. M., Jun 1 1999, In : Brain. 122, 6, p. 1093-1106 14 p.

Research output: Contribution to journalArticle

Parietal Lobe
Occipital Lobe
Magnets
Gyrus Cinguli
Motor Cortex
209 Citations (Scopus)

A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride

Levey, A. I., Bolam, J. P., Rye, D. B., Hallanger, A. E., Demuth, R. M., Mesulam, M. M. & Wainer, B. H., Jan 1 1986, In : Journal of Histochemistry and Cytochemistry. 34, 11, p. 1449-1457 9 p.

Research output: Contribution to journalArticle

Benzidines
3,3'-Diaminobenzidine
Inbred Strains Rats
Histocytochemistry
Choline O-Acetyltransferase
167 Citations (Scopus)

Alteration in connections between muscle and anterior horn motoneurons after peripheral nerve repair

Brushart, T. M. & Mesulam, M. M., Jan 1 1980, In : Science. 208, 4444, p. 603-605 3 p.

Research output: Contribution to journalArticle

Motor Neurons
Horns
Peripheral Nerves
Muscles
Sciatic Nerve
15 Citations (Scopus)

Alterations of Ca 2+ -responsive proteins within cholinergic neurons in aging and Alzheimer's disease

Riascos, D., Nicholas, A., Samaeekia, R., Yukhananov, R., Mesulam, M-M., Bigio, E. H., Weintraub, S., Guo, L. & Geula, C., Jun 1 2014, In : Neurobiology of Aging. 35, 6, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

Cholinergic Neurons
Calcium-Calmodulin-Dependent Protein Kinase Type 1
Alzheimer Disease
GAP-43 Protein
Calpain
36 Citations (Scopus)

Alterations of hippocampal acetylcholinesterase in human temporal lobe epilepsy

Green, R. C., Blume, H. W., Kupferschmid, S. B. & Mesulam, MM. M., Jan 1 1989, In : Annals of neurology. 26, 3, p. 347-351 5 p.

Research output: Contribution to journalArticle

Temporal Lobe Epilepsy
Acetylcholinesterase
Pyramidal Cells
Dentate Gyrus
Sclerosis
56 Citations (Scopus)

Alterations of visual search strategy in Alzheimer's disease and aging

Rösler, A., Mapstone, M. E., Hays, A. K., Mesulam, M-M., Rademaker, A. W., Gitelman, D. R. & Weintraub, S., Jan 1 2000, In : Neuropsychology. 14, 3, p. 398-408 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Saccades
Alzheimer Disease 8
103 Citations (Scopus)

Altered effective connectivity within the language network in primary progressive aphasia

Sonty, S. P., Mesulam, M-M., Weintraub, S., Johnson, N. A., Parrish, T. B. & Gitelman, D. R., Feb 7 2007, In : Journal of Neuroscience. 27, 6, p. 1334-1345 12 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Language
Semantics
Magnetic Resonance Imaging
Functional Neuroimaging
328 Citations (Scopus)

Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia

Mesulam, M., Wicklund, A., Johnson, N., Rogalski, E., Léger, G. C., Rademaker, A., Weintraub, S. & Bigio, E. H., Jun 1 2008, In : Annals of neurology. 63, 6, p. 709-719 11 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Alzheimer Disease
Pathology
Neurofibrillary Tangles
Autopsy
71 Citations (Scopus)

Alzheimer plaques and cortical cholinergic innervation

Mesulam, M. M., Jan 1 1986, In : Neuroscience. 17, 1, p. 275-276 2 p.

Research output: Contribution to journalArticle

Substantia Innominata
Cholinergic Fibers
Neural Pathways
Telencephalon
Septal Nuclei

Alzheimer's disease and β-amyloid

Schmaier, A. H., Van Nostrand, W., Yankner, B. A. & Mesulam, M. M., May 7 1992, In : New England Journal of Medicine. 326, 19, p. 1292-1293 2 p.

Research output: Contribution to journalLetter

Amyloid
Alzheimer Disease
Peptide Hydrolases
Serpins
Aptitude
30 Citations (Scopus)

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 1 2016, In : PloS one. 11, 2, e0148717.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer disease
Polymorphism
Gene expression
Alzheimer Disease
159 Citations (Scopus)

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

Guo, W., Chen, Y., Zhou, X., Kar, A., Ray, P., Chen, X., Rao, E. J., Yang, M., Ye, H., Zhu, L., Liu, J., Xu, M., Yang, Y., Wang, C., Zhang, D., Bigio, E. H., Mesulam, M-M., Shen, Y., Xu, Q., Fushimi, K. & 1 others, Wu, J., Jul 1 2011, In : Nature Structural and Molecular Biology. 18, 7, p. 822-831 10 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
DNA-Binding Proteins
Mutation
Proteins
Frontotemporal Lobar Degeneration
24 Citations (Scopus)

An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution

Zhu, L., Xu, M., Yang, M., Yang, Y., Li, Y., Deng, J., Ruan, L., Liu, J., Du, S., Liu, X., Feng, W., Fushimi, K., Bigio, E. H., Mesulam, M-M., Wang, C. & Wu, J., Dec 20 2014, In : Human molecular genetics. 23, 25, p. 6863-6877 15 p.

Research output: Contribution to journalArticle

Peptides
TDP-43 Proteinopathies
Amyloid
Amyloidogenic Proteins
Frontotemporal Dementia
1 Citation (Scopus)
specialization
Parietal Lobe
25 Citations (Scopus)

Anatomic, clinical, and neuropsychological correlates of spelling errors in primary progressive aphasia

Shim, H. S., Hurley, R. S., Rogalski, E. & Mesulam, M. M., Jul 1 2012, In : Neuropsychologia. 50, 8, p. 1929-1935 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Prefrontal Cortex
Phonetics
Temporal Lobe
Atrophy
34 Citations (Scopus)

Anatomical physiology of spatial extinction

Çiçek, M., Gitelman, D., Hurley, R. S. E., Nobre, A. & Mesulam, M., Dec 1 2007, In : Cerebral Cortex. 17, 12, p. 2892-2898 7 p.

Research output: Contribution to journalArticle

Parietal Lobe
Prefrontal Cortex
Perceptual Disorders
Volunteers
Magnetic Resonance Imaging
144 Citations (Scopus)
Tacrine
Physostigmine
Cholinesterases
Anatomy
Alzheimer Disease
118 Citations (Scopus)

Anatomy of language impairments in primary progressive aphasia

Rogalski, E. J., Cobia, D., Harrison, T. M., Wieneke, C., Thompson, C. K., Weintraub, S. & Mesulam, M. M., Mar 2 2011, In : Journal of Neuroscience. 31, 9, p. 3344-3350 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Atrophy
Anatomy
Language
Semantics
76 Citations (Scopus)

An electrophysiological index of stimulus unfamiliarity

Daffner, K. R., Mesulam, M-M., Scinto, L. F. M., Calvo, V., Faust, R. & Holcomb, P. J., Jan 1 2000, In : Psychophysiology. 37, 6, p. 737-747 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

An enriched-population, double-blind, placebo-controlled, crossover study of tacrine and lecithin in alzheimer’s disease

Foster, N. L., Petersen, R. C., Gracon, S. I., Lewis, K., Borison, R. L., Diamond, B. I., Chase, T., Cutler, N., Prior, P. L., Foster, N. L., Aronson, S. M., Barbas, N. R., Berent, S., Bluemlein, L. A., Gelb, D. J., Glatt, S., Karst, A., Coder, T., Gracon, S., Bahm, D. & 17 others, Higbee, M., Lewis, K. W., Mesulam, M., Daffner, K., Guinessey, J., Price, B., Weintraub, S., Petersen, R. C., Linbo, L., Reyes, P., Richter, R., Sano, M., Berkman, L. J., Schwartz, E., Smith, D., Sommer, B. & Tacrine 970-6 Study Group, Jan 1 1996, In : Dementia and Geriatric Cognitive Disorders. 7, 5, p. 260-266 7 p.

Research output: Contribution to journalArticle

Tacrine
Lecithins
Cross-Over Studies
Alzheimer Disease
Placebos
4 Citations (Scopus)

Annals of the New York Academy of Sciences: Preface

Khachaturian, Z. S. & Mesulam, M. M., Jan 1 2000, In : Annals of the New York Academy of Sciences. 924

Research output: Contribution to journalArticle

Annals