• 66820 Citations
1972 …2023
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Research Output 1972 2019

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Review article
2018
48 Citations (Scopus)

The cholinergic system in the pathophysiology and treatment of Alzheimer's disease

Hampel, H., Mesulam, M-M., Cuello, A. C., Farlow, M. R., Giacobini, E., Grossberg, G. T., Khachaturian, A. S., Vergallo, A., Cavedo, E., Snyder, P. J. & Khachaturian, Z. S., Jul 1 2018, In : Brain. 141, 7, p. 1917-1933 17 p.

Research output: Contribution to journalReview article

Cholinergic Agents
Alzheimer Disease
Therapeutics
Brain
Synapses
2015
10 Citations (Scopus)

The CARE Pathway Model for Dementia: Psychosocial and Rehabilitative Strategies for Care in Young-Onset Dementias

Morhardt, D., Weintraub, S., Khayum, B., Robinson, J., Medina, J., O'Hara, M., Mesulam, M. & Rogalski, E. J., Jun 1 2015, In : Psychiatric Clinics of North America. 38, 2, p. 333-352 20 p.

Research output: Contribution to journalReview article

Dementia
Patient Care Planning
Behavioral Symptoms
Neurobehavioral Manifestations
Caregivers
2014
87 Citations (Scopus)

Primary progressive aphasia and the evolving neurology of the language network

Mesulam, M. M., Rogalski, E. J., Wieneke, C., Hurley, R. S., Geula, C., Bigio, E. H., Thompson, C. K. & Weintraub, S., Jan 1 2014, In : Nature Reviews Neurology. 10, 10, p. 554-569 16 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Neurology
Language
Semantics
Atrophy
2013
17 Citations (Scopus)

Afasia Progressiva Primária: Uma Demência Da Rede De Linguagem

Translated title of the contribution: Primary progressive aphasia: A dementia of the language networkMesulam, M-M., Jan 1 2013, In : Dementia e Neuropsychologia. 7, 1, p. 2-9 8 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Dementia
Language
Aphasia
Atrophy
89 Citations (Scopus)

Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer's disease

Mesulam, M-M., Dec 15 2013, In : Journal of Comparative Neurology. 521, 18, p. 4124-4144 21 p.

Research output: Contribution to journalReview article

Cholinergic Agents
Alzheimer Disease
Cerebral Cortex
Tauopathies
Axons
33 Citations (Scopus)

Primary progressive aphasia and the language network: The 2013 H. Houston Merritt Lecture

Mesulam, M-M., Jul 30 2013, In : Neurology. 81, 5, p. 456-462 7 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Language
Pathology
TDP-43 Proteinopathies
Dementia
30 Citations (Scopus)

The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: The next therapeutic frontier)

Boxer, A. L., Gold, M., Huey, E., Hu, W. T., Rosen, H., Kramer, J., Gao, F. B., Burton, E. A., Chow, T., Kao, A., Leavitt, B. R., Lamb, B., Grether, M., Knopman, D., Cairns, N. J., Mackenzie, I. R., Mitic, L., Roberson, E. D., Van Kammen, D., Cantillon, M. & 23 others, Zahs, K., Jackson, G., Salloway, S., Morris, J., Tong, G., Feldman, H., Fillit, H., Dickinson, S., Khachaturian, Z. S., Sutherland, M., Abushakra, S., Lewcock, J., Farese, R., Kenet, R. O., Laferla, F., Perrin, S., Whitaker, S., Honig, L., Mesulam, M. M., Boeve, B., Grossman, M., Miller, B. L. & Cummings, J. L., Jan 1 2013, In : Alzheimer's and Dementia. 9, 2, p. 189-198 10 p.

Research output: Contribution to journalReview article

Neurodegenerative Diseases
Pharmaceutical Preparations
Disease Progression
Research
Research Personnel
2012
53 Citations (Scopus)

The evolving landscape of human cortical connectivity: Facts and inferences

Mesulam, M-M., Oct 1 2012, In : NeuroImage. 62, 4, p. 2182-2189 8 p.

Research output: Contribution to journalReview article

Brain Mapping
Cerebral Cortex
Haplorhini
Brain
Cognition
2008
75 Citations (Scopus)

Representation, inference, and transcendent encoding in neurocognitive networks of the human brain

Mesulam, M-M., Oct 1 2008, In : Annals of Neurology. 64, 4, p. 367-378 12 p.

Research output: Contribution to journalReview article

Prefrontal Cortex
Cognition
Brain
Transcend
Direction compound
2007
18 Citations (Scopus)

An update on primary progressive aphasia

Rogalski, E. & Mesulam, M., Sep 1 2007, In : Current neurology and neuroscience reports. 7, 5, p. 388-392 5 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Language
Research
241 Citations (Scopus)

The National Alzheimer's Coordinating Center (NACC) database: The uniform data set

Beekly, D. L., Ramos, E. M., Lee, W. W., Deitrich, W. D., Jacka, M. E., Wu, J., Hubbard, J. L., Koepsell, T. D., Morris, J. C., Kukull, W. A., Reiman, E. M., Kowall, N., Landreth, G., Shelanski, M., Welsh-Bohmer, K., Levey, A. I., Potter, H., Ghetti, B., Price, D., Hyman, B. & 20 others, Petersen, R. C., Sano, M., Ferris, S. H., Mesulam, M-M., Kaye, J., Bennett, D. A., Yesavage, J., Marson, D., Beck, C., DeCarli, C., Cotman, C., Cummings, J. L., Thal, L. J., Markesbery, W., Gilman, S., Trojanowski, J. Q., DeKosky, S. T., Chui, H., Rosenberg, R. & Raskind, M., Jul 1 2007, In : Alzheimer Disease and Associated Disorders. 21, 3, p. 249-258 10 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Databases
National Institute on Aging (U.S.)
Advisory Committees
Information Storage and Retrieval
2004
320 Citations (Scopus)

The Cholinergic Lesion of Alzheimer's Disease: Pivotal Factor or Side Show?

Mesulam, M-M., Jan 1 2004, In : Learning and Memory. 11, 1, p. 43-49 7 p.

Research output: Contribution to journalReview article

Cholinergic Agents
Alzheimer Disease
Neuronal Plasticity
Phosphorylation
2003
290 Citations (Scopus)

Current concepts primary progressive aphasia - A language-based dementia

Mesulam, M-M., Oct 16 2003, In : New England Journal of Medicine. 349, 16, p. 1535-1542 8 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Aphasia
Single-Photon Emission-Computed Tomography
Dementia
Differential Diagnosis
72 Citations (Scopus)

The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy

Hogg, M., Grujic, Z. M., Baker, M., Demirci, S., Guillozet, A. L., Sweet, A. P., Herzog, L. L., Weintraub, S., Mesulam, M-M., LaPointe, N. E., Gamblin, T. C., Berry, R. W., Binder, L. I., de Silva, R., Lees, A., Espinoza, M., Davies, P., Grover, A., Sahara, N., Ishizawa, T. & 4 others, Dickson, D., Yen, S. H., Hutton, M. & Bigio, E. H., Oct 1 2003, In : Acta Neuropathologica. 106, 4, p. 323-336 14 p.

Research output: Contribution to journalReview article

Tauopathies
Frontotemporal Dementia
Protein Isoforms
Mutation
Exons
2001
566 Citations (Scopus)

Primary progressive aphasia

Mesulam, M-M., Jan 1 2001, In : Annals of neurology. 49, 4, p. 425-432 8 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Dementia
Frontotemporal Dementia
Language
Frontal Lobe
1999
337 Citations (Scopus)

Neuroplasticity failure in Alzheimer's disease: Bridging the gap between plaques and tangles

Mesulam, M-M., Jan 1 1999, In : Neuron. 24, 3, p. 521-529 9 p.

Research output: Contribution to journalReview article

Neuronal Plasticity
Alzheimer Disease
1998
1683 Citations (Scopus)

From sensation to cognition

Mesulam, M-M., Jun 17 1998, In : Brain. 121, 6, p. 1013-1052 40 p.

Research output: Contribution to journalReview article

Short-Term Memory
Cognition
Parietal Lobe
Prefrontal Cortex
Language
1997
687 Citations (Scopus)

Practice guideline for the treatment of patients with schizophrenia

Herz, M. I., Liberman, R. P., McGlashan, T. H., Lieberman, J. A., Wyatt, R. J., Marder, S. R., Wang, P., Allgulander, C., Baldessarini, R. J., Balon, R., Bellack, A. S., Berlin, J., Blackington, C. H., Buckley, P., Carlson, D. G., Cott, J., Cournos, F., Desai, P., Dickstein, L., Fenton, W. S. & 78 others, Fisher, W. A., Flaherty, L. T., Freedman, R., Galanter, M., Galton, E., Ganguli, R., Garrettson, L. K., Goldfinger, S., Goldman, L. S., Goldstein, M. Z., Gordy, T. R., Gray, S. H., Green, M. R., Greenberg, W. M., Gunderson, J. G., Hall, L. L., Haller, E., Hanin, E., Hawkins, L., Hester, T. W., Horn, T., Hsiao, J. K., Juthani, N. V., Kane, J. M., Kayser, A., Kibel, H. D., Kimmich, R. A., Koegler, R. R., Krajeski, J., Kuehnel, T., Lamberti, J. S., Lehman, A., Leunello, J., Martin, R. L., McCarley, R., McGee, M., Meltzer, H. Y., Mesulam, M., Metzner, J. L., Mosher, L. R., Motto, J. A., Mueser, K. T., Munoz, R. A., Nasrallah, H. A., Newcomer, J. W., Opler, L. A., Peterson, G. N., Rapaport, M., Riba, M., Rickert, V. I., Rifkin, A., Rivenbark, J. S., Robertson, S., Ruiz, P., Ryan, W. G., Sanderson, M. O., Schiffer, R. B., Schyve, P. M., Sebring, R. H., Shen, W. W., Shore, D., Simpson, G. M., Soufi, H. E., Stein, L. I., Stotland, N., Strauss, J., Sundberg, D., Svendsen, D., Tohen, M., Tsuang, M., Wagnitz, J. G., Weiner, R., Weitzel, W. D., Wilkerson, L. J., Wingerson, D., Zarate, J., Zito, J. & Zonana, H. V., Jan 1 1997, In : American Journal of Psychiatry. 154, 4 SUPPL., p. 1-63 63 p.

Research output: Contribution to journalReview article

1995
169 Citations (Scopus)

Cholinesterases and the pathology of Alzheimer disease

Geula, C. & Mesulam, M. M., Jan 1 1995, In : Alzheimer Disease and Associated Disorders. 9, SUPPL. 2, p. 23-28 6 p.

Research output: Contribution to journalReview article

Cholinesterases
Alzheimer Disease
Pathology
Acetylcholinesterase
Axons
1993
18 Citations (Scopus)

Asymmetric catalepsy after right hemisphere stroke

Saver, J. L., Greenstein, P., Ronthal, M. & Mesulam, M. M., Jan 1 1993, In : Movement Disorders. 8, 1, p. 69-73 5 p.

Research output: Contribution to journalReview article

Catatonia
Catalepsy
Parietal Lobe
Negativism
Stroke
1992
113 Citations (Scopus)

Spectrum of primary progressive aphasia.

Mesulam, M. M. & Weintraub, S., Jan 1 1992, In : Baillière's clinical neurology. 1, 3, p. 583-609 27 p.

Research output: Contribution to journalReview article

Primary Progressive Aphasia
Language Disorders
Aphasia
Memory Disorders
Dementia
1991
193 Citations (Scopus)

β-Amyloid and the pathogenesis of alzheimer's disease

Yankner, B. A. & Mesulam, M. M., Dec 26 1991, In : New England Journal of Medicine. 325, 26, p. 1849-1857 9 p.

Research output: Contribution to journalReview article

Amyloid
Alzheimer Disease
Factitious Disorders
Pick Disease of the Brain
Progressive Supranuclear Palsy
1990
17 Citations (Scopus)
Tacrine
Physostigmine
Cholinesterases
Acetylcholinesterase
Cerebral Cortex
1989
7 Citations (Scopus)

Behavioral neuroanatomy of cholinergic innervation in the primate cerebral cortex.

Mesulam, M. M., Dec 1 1989, In : EXS. 57, p. 1-11 11 p.

Research output: Contribution to journalReview article

Neuroanatomy
Cerebral Cortex
Cholinergic Agents
Primates
Anatomy
1984
248 Citations (Scopus)

Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase

Wainer, B. H., Levey, A. I., Mufson, E. J. & Mesulam, M. M., Jan 1 1984, In : Neurochemistry International. 6, 2, p. 163-182 20 p.

Research output: Contribution to journalReview article

Choline O-Acetyltransferase
Cholinergic Agents
Antibodies
Brain
1983
89 Citations (Scopus)
Cerebral Dominance
Parietal Lobe
Anatomy
Aptitude
Gyrus Cinguli
1979
10 Citations (Scopus)

Acute behavioral derangements without hemiplegia in cerebrovascular accidents

Mesulam, M. M., Dec 1 1979, In : Primary Care - Clinics in Office Practice. 6, 4, p. 813-826 14 p.

Research output: Contribution to journalReview article

Mental Processes
Hemiplegia
Coordination Complexes
Language
Stroke