Grants per year
Personal profile
Research Interests
Airway inflammation in asthma and COPD. Effects of hypercapnia (elevated levels of CO2) on innate immunity and host defense in the lung. Effects of hypercapnia on airway biology.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biochemistry, National University of Cordoba, Argentina
… → 1997
PharmD, National University of Cordoba, Argentina
… → 1992
Research interests keywords
- Asthma
- Cell Imaging
- Chronic Obstructive Pulmonary Disease (COPD)
- Cigarette Smoking
- Immune Regulation
- Infectious Diseases: Bacteria
- Infectious Diseases: Viral
- Inflammation
- Molecular Biology
- Respiratory Diseases
- Signal Transduction
Fingerprint
- 1 Similar Profiles
Network
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IPA for Marina S. Casalino Matsuda, PhD with Jesse Brown VA Medical Center
Sporn, P. H. & Casalino Matsuda, M. S.
10/1/22 → 9/30/23
Project: Research project
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Targeting abnormal alveolar immune activation and failed epithelial repair in COVID-19
Budinger, G. S., Misharin, A., Abdala-Valencia, H., Braun, R. I., Casalino Matsuda, M. S., Horvath, C. M., Lomasney, J. W., Prakriya, M., Wunderink, R. G., Yamashita, M. & Casalino Matsuda, M. S.
National Heart, Lung, and Blood Institute
4/1/22 → 3/31/26
Project: Research project
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Targeting abnormal alveolar immune activation in COVID-19
Budinger, G. S., Chandel, N., Horvath, C. M., Kelleher, N. L., Misharin, A., Prakriya, M., Wunderink, R. G. & Casalino Matsuda, M. S.
Northwestern Memorial Hospital
4/1/21 → 3/31/24
Project: Research project
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Covid Administrative Supplement
Casalino Matsuda, M. S., Misharin, A. & Budinger, G. S.
6/1/20 → 3/31/25
Project: Research project
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Hypercapnia and Suppression of Anti-viral Host Defense
Sporn, P. H. & Casalino Matsuda, M. S.
National Heart, Lung, and Blood Institute
9/17/16 → 8/31/17
Project: Research project
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Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells
Dada, L. A., Welch, L. C., Magnani, N. D., Ren, Z., Han, H., Brazee, P. L., Celli, D., Flozak, A. S., Weng, A., Herrerias, M. M., Kryvenko, V., Vadász, I., Runyan, C. E., Abdala-Valencia, H., Shigemura, M., Casalino-Matsuda, S. M., Misharin, A. V., Budinger, G. R. S., Gottardi, C. J. & Sznajder, J. I., Feb 22 2023, In: JCI Insight. 8, 4, e159331.Research output: Contribution to journal › Article › peer-review
Open Access -
Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage
Casalino-Matsuda, S. M., Berdnikovs, S., Wang, N., Nair, A., Gates, K. L., Beitel, G. J. & Sporn, P. H. S., Apr 6 2021, In: Interface Focus. 11, 2, 20200039.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Epithelial cell–specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice
Do-Umehara, H. C., Chen, C., Zhang, Q., Misharin, A. V., Abdala-Valencia, H., Casalino-Matsuda, S. M., Reyfman, P. A., Anekalla, K. R., Gonzalez-Gonzalez, F. J., Sala, M. A., Peng, C., Wu, P., Wong, C. C. L., Kalhan, R., Bharat, A., Perlman, H., Ridge, K. M., Sznajder, J. I., Sporn, P. H. S., Chandel, N. S., & 6 others , Aug 2020, In: Science Advances. 6, 33, eabb7238.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Hypercapnia suppresses macrophage antiviral activity and increases mortality of influenza a infection via akt1
Casalino-Matsuda, S. M., Chen, F., Gonzalez-Gonzalez, F. J., Nair, A., Dib, S., Yemelyanov, A., Gates, K. L., Budinger, G. R. S., Beitel, G. J. & Sporn, P. H. S., Jul 15 2020, In: Journal of Immunology. 205, 2, p. 489-501 13 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans
Shigemura, M., Lecuona, E., Angulo, M., Dada, L. A., Edwards, M. B., Welch, L. C., Casalino-Matsuda, S. M., Sporn, P. H. S., Vadász, I., Helenius, I. T., Nader, G. A., Gruenbaum, Y., Sharabi, K., Cummins, E., Taylor, C., Bharat, A., Gottardi, C. J., Beitel, G. J., Kaminski, N., Budinger, G. R. S., & 2 others , Dec 1 2019, In: Scientific reports. 9, 1, 18251.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations
Datasets
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Supplementary material from "Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage"
Casalino Matsuda, M. S. (Creator), Berdnikovs, S. (Creator), Wang, N. (Contributor), Nair, A. (Creator), Gates, K. L. (Contributor), Beitel, G. J. (Creator) & Sporn, P. H. (Creator), The Royal Society, 2021
DOI: 10.6084/m9.figshare.c.5290088.v1, https://rs.figshare.com/collections/Supplementary_material_from_Hypercapnia_selectively_modulates_LPS-induced_changes_in_innate_immune_and_DNA_replication-related_gene_transcription_in_the_macrophage_/5290088/1
Dataset
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Mouse_transcrpts from Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage
Casalino Matsuda, M. S. (Creator), Berdnikovs, S. (Creator), Wang, N. (Contributor), Nair, A. (Creator), Gates, K. L. (Contributor), Beitel, G. J. (Creator) & Sporn, P. H. (Creator), The Royal Society, 2021
DOI: 10.6084/m9.figshare.13698020.v1, https://rs.figshare.com/articles/dataset/Mouse_transcrpts_from_Hypercapnia_selectively_modulates_LPS-induced_changes_in_innate_immune_and_DNA_replication-related_gene_transcription_in_the_macrophage/13698020/1
Dataset
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Human_Transcripts from Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage
Casalino Matsuda, M. S. (Creator), Berdnikovs, S. (Creator), Wang, N. (Contributor), Nair, A. (Creator), Gates, K. L. (Contributor), Beitel, G. J. (Creator) & Sporn, P. H. (Creator), The Royal Society, 2021
DOI: 10.6084/m9.figshare.13698029.v1, https://rs.figshare.com/articles/dataset/Human_Transcripts_from_Hypercapnia_selectively_modulates_LPS-induced_changes_in_innate_immune_and_DNA_replication-related_gene_transcription_in_the_macrophage/13698029/1
Dataset