Grants per year
Personal profile
Education/Academic qualification
PhD, Northwestern University
… → 2012
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Dive into the research topics where Mario Shields is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Co-targeting BET Bromodomain Proteins and MNK Kinases in Pancreatic Cancer
Munshi, H. G., Bentrem, D. J., Shields, M. & Zhang, B.
4/1/22 → 3/31/27
Project: Research project
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Par3 deficiency promotes fatty replacement in chronic pancreatitis
American Pancreatic Association
7/1/20 → 5/31/21
Project: Research project
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Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
Shields, M. A., Spaulding, C., Metropulos, A. E., Khalafalla, M. G., Pham, T. N. D. & Munshi, H. G., Mar 1 2022, In: Cell reports. 38, 9, 110441.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibiting MNKs promote macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity
Pham, T. N. D., Spaulding, C., Shields, M. A., Metropulos, A. E., Shah, D. N., Khalafalla, M. G., Principe, D. R., Bentrem, D. J. & Munshi, H. G., May 9 2022, In: JCI Insight. 7, 9, e152731.Research output: Contribution to journal › Article › peer-review
Open Access -
Preclinical models of pancreatic ductal adenocarcinoma and their utility in immunotherapy studies
Pham, T. N. D., Shields, M. A., Spaulding, C., Principe, D. R., Li, B., Underwood, P. W., Trevino, J. G., Bentrem, D. J. & Munshi, H. G., 2021, In: Cancers. 13, 3, p. 1-22 22 p., 440.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations -
A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
Barth, N. D., Subiros-Funosas, R., Mendive-Tapia, L., Duffin, R., Shields, M. A., Cartwright, J. A., Henriques, S. T., Sot, J., Goñi, F. M., Lavilla, R., Marwick, J. A., Vermeren, S., Rossi, A. G., Egeblad, M., Dransfield, I. & Vendrell, M., Dec 1 2020, In: Nature communications. 11, 1, 4027.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Quercetin enhances the anti-tumor effects of BET inhibitors by suppressing hnRNPA1
Pham, T. N. D., Stempel, S., Shields, M. A., Spaulding, C., Kumar, K., Bentrem, D. J., Matsangou, M. & Munshi, H. G., Sep 1 2019, In: International journal of molecular sciences. 20, 17, 4293.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations