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Personal profile

Research Interests

My research focuses on the basal ganglia, a group of subcortical brain nuclei that are critical for voluntary movement and associative learning and are the primary sites of dysfunction in Parkinson’s disease, Huntington’s disease, obsessive-compulsive disorder and addiction. My objectives are to define the principles underlying the normal and pathological operation of the basal ganglia. My hope is that this information will provide the foundation for the rational development of corrective or neuroprotective therapies.

Education/Academic qualification

PhD, University of Manchester

… → 1993

Keywords

  • Nervous System Diseases
  • Neuroscience
  • Pharmacology
  • Physiology

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 2003 2023

Subthalamic Nucleus
National Institute of Neurological Disorders and Stroke
Isradipine
Phase III Clinical Trials
Globus Pallidus
trainee
training program
Disease
interdisciplinary research
clubs
Subthalamic Nucleus
Neuronal Plasticity
Synaptic Transmission
Parkinson Disease
Parkinsonian Disorders

Research Output 1990 2017

13 Citations (Scopus)

Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons

Chu, H., McIver, E. L., Kovaleski, R. F., Atherton, J. F. & Bevan, M. D., Sep 13 2017, In : Neuron. 95, 6, p. 1306-1318.e5

Research output: Contribution to journalArticle

Subthalamic Nucleus
Dopaminergic Neurons
Mesencephalon
N-Methyl-D-Aspartate Receptors
Parkinson Disease
1 Citation (Scopus)

The Subthalamic Nucleus

Bevan, M. D., Jan 1 2017, Handbook of Behavioral Neuroscience. Elsevier B.V., p. 277-291 15 p. (Handbook of Behavioral Neuroscience; vol. 24).

Research output: Chapter in Book/Report/Conference proceedingChapter

Subthalamic Nucleus
Basal Ganglia
Neurons
Disruptive, Impulse Control, and Conduct Disorders
Globus Pallidus
7 Citations (Scopus)

Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of huntington’s disease

Atherton, J. F., McIver, E. L., Mullen, M. R. M., Wokosin, D. L., Surmeier Jr, D. J. & Bevan, M. D., Dec 20 2016, In : eLife. 5, DECEMBER2016, e21616.

Research output: Contribution to journalArticle

Subthalamic Nucleus
Huntington Disease
N-Methyl-D-Aspartate Receptors
Neurons
KATP Channels
32 Citations (Scopus)
Subthalamic Nucleus
Globus Pallidus
Motor Cortex
N-Methyl-D-Aspartate Receptors
GABA-A Receptors
49 Citations (Scopus)

New roles for the external globus pallidus in basal ganglia circuits and behavior

Gittis, A. H., Berke, J. D., Bevan, M. D., Chan, S., Mallet, N., Morrow, M. M. & Schmidt, R., Nov 12 2014, In : Journal of Neuroscience. 34, 46, p. 15178-15183 6 p.

Research output: Contribution to journalArticle

Globus Pallidus
Basal Ganglia
Aptitude
Electrophysiology
Transgenic Mice