Grants per year
Personal profile
Research Interests
My research focuses on the basal ganglia, a group of subcortical brain nuclei that are critical for voluntary movement and associative learning and are the primary sites of dysfunction in Parkinson’s disease, Huntington’s disease, obsessive-compulsive disorder and addiction. My objectives are to define the principles underlying the normal and pathological operation of the basal ganglia. My hope is that this information will provide the foundation for the rational development of corrective or neuroprotective therapies.
Education/Academic qualification
PhD, University of Manchester
… → 1993
Research interests
- Nervous System Diseases
- Neuroscience
- Pharmacology
- Physiology
Fingerprint Dive into the research topics where Mark D Bevan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 18 Similar Profiles
Subthalamic Nucleus
Medicine & Life Sciences
Globus Pallidus
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Basal Ganglia
Medicine & Life Sciences
Entopeduncular Nucleus
Medicine & Life Sciences
Action Potentials
Medicine & Life Sciences
Dopaminergic Neurons
Medicine & Life Sciences
Parkinson Disease
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2003 2023
General Motor Control Mechanisms and Disease Training Program
Bevan, M. D. & Surmeier Jr, D. J.
National Institute of Neurological Disorders and Stroke
7/1/18 → 6/30/23
Project: Research project
trainee
training program
Disease
interdisciplinary research
clubs
Neural Adaptations in Huntington's Disease
Atherton, J. F., Bevan, M. D., Day, M., Kondapalli, J., Pancani, T., Surmeier Jr, D. J., Wokosin, D. L. & Xie, Z.
4/1/18 → 3/31/21
Project: Research project
Huntington Disease
Down-Regulation
Apamin
Phenotype
Neurons
Northwestern University Interdepartmental Neuroscience Postbaccalaureate Research Education Program
Acosta, A., Allada, R., Apkarian, A., Awatramani, R., Beeman, M., Bevan, M. D., Bozza, T. C., Cang, J., Chetkovich, D. M., Cobia, D. J., Contractor, A., Corcos, D. M., DeVries, S. H., Dewald, J. P. A., Dhar, S., Disterhoft, J. F., Dombeck, D. A., Elliott, J. M., Feng, Y., Ferreira, A. B., Gallio, M., Garcia-Anoveros, J., George Jr, A. L., Geula, C., Gordon, K. E., Gottfried, J. A., Grafman, J. H., Hartmann, M. J. Z., Heckman, C., Hespos, S. J., Jayaraman, A., Kahnt, T., Kearney, J. A., Kessler, J., Kiskinis, E., Kohtz, J., Kording, K. P., Kozorovitskiy, Y., Krainc, D., Larson, C., Lee, S. S. M., Li, L., Losh, M. C., Maccaferri, G., MacIver, M. A., Martina, M., Mazzulli, J., McLean, D., Mesulam, M., Miller, L. E., Miller, R. J., Mussa-Ivaldi, F., Nusslock, R., Opal, P., Ozdinler, P. H., Paller, K., Parrish, T. B., Prakriya, M., Radulovic, J., Raman, I. M., Reber, P. J., Redei, E., Rogalski, E., Sanchez, J. T., Sanz-Clemente, A., Savas, J. N., Schmidt, T. M., Schwartz, G. W., Segraves, M., Shepherd, G. M. G., Siddique, T., Solla, S. A., Surmeier Jr, D. J., Swanson, G. T., Topczewski, J., Tresch, M. C., Tysseling, V. M., Vassar, R. J., Voss, J. L., Wainwright, D. A., Wang, L., Weintraub, S., Woolley, C. S. & Wright, B. A.
National Institute of General Medical Sciences
5/1/17 → 4/30/22
Project: Research project
neurosciences
graduate
university
education
Synaptic Transmission, Plasticity, and Integration in the Subthalamic Nucleus
National Institute of Neurological Disorders and Stroke
6/1/16 → 5/31/20
Project: Research project
Subthalamic Nucleus
Neuronal Plasticity
Synaptic Transmission
Parkinson Disease
Parkinsonian Disorders
Subproject for Institution # SP0050128
Bevan, M. D. & Chu, H.
National Institute of Neurological Disorders and Stroke
9/15/18 → 8/31/19
Project: Research project
Subthalamic Nucleus
National Institute of Neurological Disorders and Stroke
Isradipine
Phase III Clinical Trials
Globus Pallidus
Research Output 1990 2019
Maladaptive Downregulation of Autonomous Subthalamic Nucleus Activity following the Loss of Midbrain Dopamine Neurons
McIver, E. L., Atherton, J. F., Chu, H. Y., Cosgrove, K. E., Kondapalli, J., Wokosin, D. L., Surmeier Jr, D. J. & Bevan, M. D., Jul 23 2019, In : Cell reports. 28, 4, p. 992-1002.e4Research output: Contribution to journal › Article
Open Access
Subthalamic Nucleus
Dopaminergic Neurons
Mesencephalon
Neurons
Dopamine
24
Citations
(Scopus)
Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons
Chu, H., McIver, E. L., Kovaleski, R. F., Atherton, J. F. & Bevan, M. D., Sep 13 2017, In : Neuron. 95, 6, p. 1306-1318.e5Research output: Contribution to journal › Article
Subthalamic Nucleus
Dopaminergic Neurons
Mesencephalon
N-Methyl-D-Aspartate Receptors
Parkinson Disease
8
Citations
(Scopus)
Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of huntington’s disease
Atherton, J. F., McIver, E. L., Mullen, M. R. M., Wokosin, D. L., Surmeier, D. J. & Bevan, M. D., Dec 20 2016, In : eLife. 5, DECEMBER2016, e21616.Research output: Contribution to journal › Article
Subthalamic Nucleus
Huntington Disease
N-Methyl-D-Aspartate Receptors
Neurons
KATP Channels
1
Citation
(Scopus)
The Subthalamic Nucleus
Bevan, M. D., Jan 1 2016, Handbook of Behavioral Neuroscience. Elsevier B.V., p. 277-291 15 p. (Handbook of Behavioral Neuroscience; vol. 24).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Subthalamic Nucleus
Basal Ganglia
Neurons
Disruptive, Impulse Control, and Conduct Disorders
Globus Pallidus
41
Citations
(Scopus)
Heterosynaptic regulation of external globus pallidus inputs to the subthalamic nucleus by the motor cortex
Chu, H. Y., Atherton, J. F., Wokosin, D., Surmeier, D. J. & Bevan, M. D., Jan 21 2015, In : Neuron. 85, 2, p. 364-376 13 p.Research output: Contribution to journal › Article
Subthalamic Nucleus
Globus Pallidus
Motor Cortex
N-Methyl-D-Aspartate Receptors
GABA-A Receptors