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Mark E Molitch

  • 21876 Citations
1969 …2020

Research output per year

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Personal profile

Research Interests

Pathogenesis & treatment of pituitary tumors, treatment of diabetic complications

Certifications and Licenses

Internal Medicine
Endocrinology, Diabetes & Metabolism

Training Experience

1972Residency, Hospital of the University of Pennsylvania
1975Fellowship, Univ. of CA-Los Angeles Med. Ctr.

Education/Academic qualification

MD, University of Pennsylvania

… → 1969

Research interests

  • Diabetes
  • Endocrinology
  • Medicine
  • Metabolism

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Grants

Prot#CRN00808-02: A Double-blind, Placebo-controlled, Randomized Withdrawal Study to Evaluate the Safety, Pharmacokinetics and Efficacy of CRN00808 in Patients with Acromegaly that are Responders to Octreotide Lar or Landreotide (ACROBAT EVOLVE)

Molitch, M. E.

Accelsiors CRO and Consultancy Services Ltd., Crinetics Pharmaceuticals, Inc.

8/6/19 → 8/6/22

Project: Research project

Prot#CRN00808-03: An Open Label Exploratory Study to Evaluate the Safety, Pharmacokinetics and Efficacy of CRN00808 in Patients with Acromegaly Treated with Somatostatin Analogue Based Treatment Regimens (ACROBAT EDGE)

Molitch, M. E.

Accelsiors CRO and Consultancy Services Ltd., Crinetics Pharmaceuticals, Inc.

8/6/19 → 8/6/22

Project: Research project

Prot#CLCI699C2X01B: An Open-label, Multi-Center, Roll-Over Study to Assess Long Term Safety in Patients with Endogenous Cushing’s Syndrome Who Have Completed a Prior Novartis-Sponsored Osilodrostat (LCI699) Study and are Judged by the Investigator to Bene

Huang, W. & Molitch, M. E.

Novartis Pharmaceuticals Corporation

5/22/19 → 12/31/24

Project: Research project

Preventing Early Renal Loss Follow-up Study (PERLage)

Molitch, M. E.

Joslin Diabetes Center, Inc., JDRF International

5/16/19 → 10/31/20

Project: Research project

Prot#: ISIS 766720-CS2: A Double Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability, and Efficacy of ISIS 766720 (IONIS GHR-LRX, an Antisense Inhibitor of the Growth Hormone Receptor) Administered Once Every 28 Days for 16 Weeks i

Huang, W. & Molitch, M. E.

Medpace Clinical Research LLC, Ionis Pharmaceuticals, Inc.

4/3/19 → 4/3/22

Project: Research project

Research Output

A special thanks to the reviewers of diabetes care

Sue Kirkman, M., Bolli, G. B., Molitch, M., Perkins, B. A., Harding, J. L., Buse, J., Wolfsdorf, J. I., Dungan, K. M., David Leslie, R. & Shaw, J. E., May 1 2020, In : Diabetes care. 43, 5, 1 p.

Research output: Contribution to journal › Editorial

Open Access

DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes

Roshandel, D., Chen, Z., Canty, A. J., Bull, S. B., Natarajan, R., Paterson, A. D., Scherer, S., Miao, F., Zhang, L., Brown-Friday, J., Crandall, J., Engel, H., Engel, S., Martinez, H., Phillips, M., Reid, M., Shamoon, H., Sheindlin, J., Gubitosi-Klug, R., Wood, J. & 528 others, Mayer, L., Miller, D., Nayate, A., Novak, M., Pendegast, S., Singerman, L., Weiss, D., Zegarra, H., Brown, E., Crawford, P., Genuth, S., Palmert, M., Pugsley, P., Quin, J., Smith-Brewer, S., Dahms, W., McConnell, J., Beck, C., Farrell, K., Gaston, P., Trail, R., Monnier, V., Sell, D., Strauch, C., Gregory, N. S., Hanna, R., Chan, R., Kiss, S., Orlin, A., Rubin, M., Barron, S., Bosco, B., Brillon, D., Chang, S., Dwoskin, A., Heinemann, M., Jovanovic, L., Lackaye, M. E., Lee, T., Levy, B., Reppucci, V., Richardson, M., Campbell, R., Bhan, A., Jones, J. K., Kruger, D., Edwards, P. A., Remtema, H., Angus, E., Galprin, A., McLellan, M., Thomas, A., Carey, J. D., Whitehouse, F., Bergenstal, R., Dunnigan, S., Gunyou, K., Johnson, M., Carlson, A., Thomas, L., Birk, R., Callahan, P., Castle, G., Cuddihy, R., Franz, M., Freking, D., Gill, L., Gott, J., Hollander, P., Kendall, D., Laechelt, J., List, S., Mestrezat, W., Nelson, J., Olson, B., Rude, N., Spencer, M., Etzwiler, D., Morgan, K., Aiello, L. P., Golden, E., Arrigg, P., Beaser, R., Bestourous, L., Cavallerano, J., Cavicchi, R., Ganda, O., Hamdy, O., Murtha, T., Schlossman, D., Shah, S., Sharuk, G., Silva, P., Silver, P., Stockman, M., Sun, J., Weimann, E., Aiello, L. M., Asuquo, V., Jacobson, A., Kirby, R., Rand, L., Rosenzwieg, J., Wolpert, H., Nathan, D. M., Larkin, M. E., Cayford, M., De Manbey, A., Gurry, L., Heier, J., Joseph, A., Leandre, F., Martin, K., Shah, C., Stevens, C., Thangthaeng, N., Anderson, E., Bode, H., Brink, S., Christofi, M., Cornish, C., Cros, D., Crowell, S., Delahanty, L., Folino, K., Fritz, S., Gauthier-Kelly, C., Godine, J., Haggan, C., Hansen, K., Lou, P., Lynch, J., McKitrick, C., Moore, D., Norman, D., Ong, M., Ryan, E., Taylor, C., Zimbler, D., Vella, A., Ziegler, G., Barkmeier, A., French, B., Haymond, M., Mortenson, J., Pach, J., Rizza, R., Schmidt, L., Schwenk, W. F., Service, F. J., Woodwick, R., Colligan, R., Lucas, A., Zimmerman, B., Nickander, K., Low, P., Sommer, C., Lopes-Virella, M., Luttrell, L., Spillers, L., Fernandes, J., Hermayer, K., Kwon, S., Lee, K., Lyons, T., Nutaitis, M., Blevins, A., Bracey, M., Caulder, S., Colwell, J., Elsing, S., Farr, A., Lee, D., Lindsey, P., Mayfield, R., Parker, J., Patel, N., Pittman, C., Selby, J., Soule, J., Szpiech, M., Thompson, T., Wood, D., Yacoub-Wasef, S., Jenkins, A., Klein, R., Virella, G., Jaffa, A., Carter, R., Stoner, J., Garvey, W. T., Lackland, D., Brabham, M., McGee, D., Zheng, D., Mayfield, R. K., Molitch, M., Wallia, A., Adelman, D., Hartmuller, M., Ajroud-Driss, S., Astelford, P., Degillio, A., Gill, M., Jampol, L., Johnson, C., Kaminski, L., Leloudes, N., Lyon, A., Mirza, R., Ryan, D., Simjanoski, E., Strugula, Z., Colson, S., Schaefer, B., Kolterman, O., Mudaliar, S., Lorenzi, G., Goldbaum, M., Clark, T., Giotta, M., Grant, I., Jones, K., Lyon, R., Prince, M., Reed, R., Swenson, M., Friedenberg, G., Sivitz, W. I., Vittetoe, B., Kramer, J., Bayless, M., Fountain, C., Hoffman, R., MacIndoe, J., Olson, N., Schrott, H., Snetselaar, L., Weingeist, T., Zeitler, R., Miller, R., Johnsonbaugh, S., Carney, M., Counts, D., Donner, T., Gordon, J., Hebdon, M., Hemady, R., Jones, B., Kowarski, A., Liss, R., Mendley, S., Ostrowski, D., Patronas, M., Salemi, P., Steidl, S., Herman, W. H., Martin, C. L., Lee, P., Albers, J. W., Pop-Busui, R., Feldman, E. L., Greene, D. A., Stevens, M. J., Burkhart, N., Sandford, T., Floyd, J., Sarma, A., Dunn, R., Speigelberg, T., Bantle, J., Flaherty, N., Koozekanani, D., Montezuma, S., Terry, J., Goetz, F., Kwong, C., McKenzie, L., Mech, M., Olson, J., Rogness, B., Strand, T., Warhol, R., Wimmergren, N., Steffes, M., Karger, A., Seegmiller, J., Arends, V., Bucksa, J., Chavers, B., Killeen, A., Nowicki, M., Saenger, A., Crow, R., Gloeb, B., O'Donnell, C., Thomas, S., Goldstein, D., Hainsworth, D., Hitt, S., Giangiacomo, J., Schade, D. S., Canady, J. L., Avery, R. B., Burge, M. R., Chapin, J. E., Das, A., Ketai, L. H., Hornbeck, D., Johannes, C., Rich, J., Schluter, M. L., Schutta, M., Bourne, P. A., Brucker, A., Braunstein, S., Maschak-Carey, B. J., Schwartz, S., Baker, L., Orchard, T., Cimino, L., Rubinstein, D., Becker, D., Doft, B., Finegold, D., Kelly, K., Lobes, L., Silvers, N., Songer, T., Steinberg, D., Steranchak, L., Wesche, J., Drash, A., Ryan, C., Burzuk, B., Cupelli, E., Geckle, M., Sandstrom, D., Thoma, F., Williams, T., Woodfill, T., Malone, J. I., Morrison, A., Bernal, M. L., Pavan, P. R., Babbione, L., Declue, T. J., Grove, N., McMillan, D., Solc, H., Tanaka, E. A., Vaccaro-Kish, J., Dagogo-Jack, S., Wigley, C., Huddleston, S., Patel, A., Bryer-Ash, M., Chaum, E., Iannacone, A., Lambeth, H., Meyer, D., Moser, S., Murphy, M. B., Ricks, H., Schussler, S., Yoser, S., Kitabchi, A., Raskin, P., Strowig, S., He, Y. G., Mendelson, E., Ufret-Vincenty, R. L., Basco, M., Cercone, S., Sun, L., Boright, A., Perkins, B. A., Zinman, B., Barnie, A., Bakshi, N., Brent, M., Devenyi, R., Koushan, K., Mandelcorn, M., Perdikaris, F., Tuason, L., Daneman, D., Ehrlich, R., Ferguson, S., Gordon, A., Perlman, K., Rogers, S., Palmer, J., Fahlstrom, R., De Boer, I. H., De Koo, L. O., Van Ottingham, L., Catton, S., Ginsberg, J., Kinyoun, J., Brunzell, J., Purnell, J., Wessells, H., Holt, S., Hotaling, J., Kim, C., Clemens, Q., Brown, J., McDonald, C., Driscoll, M., Bylsma, J., Sheidow, T., Brown, W., Canny, C., Colby, P., Debrabandere, S., Dupre, J., Harth, J., Hramiak, I., Jenner, M., Mahon, J., Nicolle, D., Rodger, N. W., Smith, T., Crofford, O., May, M., Hagan, J. L., Ramker, R., Adkins, T., Agarwal, A., Lovell, C., Feman, S., Lorenz, R., Survant, L., White, N. H., Levandoski, L., Boniuk, I., Santiago, J., Tamborlane, W., Gatcomb, P., Stoessel, K., Ahern, J., Fong, K., Ossorio, P., Ramos, P., Lachin, J., Bebu, I., Braffett, B., Backlund, J., Diminick, L., Gao, X., Kenny, D., Klumpp, K., Lin, M., Trapani, V., Anderson, K., Chan, K., Cleary, P., Determan, A., Dews, L., Hsu, W., McGee, P., Pan, H., Petty, B., Rosenberg, D., Rutledge, B., Sun, W., Villavicencio, S., Younes, N., Williams, C., Cowie, C., Siebert, C., Harrington, A., O'Leary, D., Polak, J., Funk, L., Soliman, E. Z., Barr, M., Campbell, C., Hensley, S., Hu, J., Keasler, L., Li, Y., Taylor, T., Zhang, Z. M., Prineas, R., Blodi, B., Danis, R., Lawrence, D., Wabers, H., Burger, M., Davis, M., Dingledine, J., Gama, V., Gangaputra, S., Hubbard, L., Neill, S., Sussman, R., Cruickshanks, K., Dalton, D., Bainbridge, K., Budoff, M., Darabian, S., Rezaeian, P., Detrano, R., Fox, M., Kim, L., Oudiz, R., Wong, N., Lima, J., Bluemke, D., Turkbey, E., Chahal, H., Jain, A., Jarboe, R., Liu, C., Malayeri, A., Miao, C., Van Der Geest, R. J., Hazen, S., Pratt, A., Tang, W., Maynard, J., Farquhar, J., Moran, M., Pfiefer, M., Schumer, M. & McVary, K., Apr 5 2020, In : Clinical Epigenetics. 12, 1, 52.

Research output: Contribution to journal › Article

Open Access

    • Growth hormone replacement in adults: Real-world data from two large studies in US and Europe

    Weber, M. M., Gordon, M. B., Höybye, C., Jørgensen, J. O. L., Puras, G., Popovic-Brkic, V., Molitch, M. E., Ostrow, V., Holot, N., Pietropoli, A. & Biller, B. M. K., Feb 2020, In : Growth Hormone and IGF Research. 50, p. 71-82 12 p.

    Research output: Contribution to journal › Article

    • Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association

    Rangaswami, J., Bhalla, V., Blair, J. E. A., Chang, T. I., Costa, S., Lentine, K. L., Lerma, E. V., Mezue, K., Molitch, M., Mullens, W., Ronco, C., Tang, W. H. W. & Mccullough, P. A., Apr 16 2019, In : Circulation. 139, 16, p. E840-E878

    Research output: Contribution to journal › Article

    Open Access
    • 45 Scopus citations

    Early glomerular hyperfiltration and long-term kidney outcomes in type 1 diabetes: The DCCT/EDIC experience

    Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Jun 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 6, p. 854-861 8 p.

    Research output: Contribution to journal › Article

    • 5 Scopus citations