Grants per year
Personal profile
Research Interests
Professor Johnson is internationally known for his work on ocular biomechanics, particular with regards to the pathogenesis of glaucoma and age-related macular degeneration. Studies in his group currently involve a bioengineering approach that utilize perfusion studies, atomic force microscopy and theoretical analysis in combination with use of high-resolution morphometry and finite element modeling.
Education/Academic qualification
Mechanical Engineering, PhD, Massachusetts Institute of Technology
… → 1987
Interdisciplinary Engineering, BS, Purdue University
… → 1975
Mechanical Engineering, MS, Massachusetts Institute of Technology
Mathematics, Purdue University
Research interests
- Age-Related Macular Degeneration
- Biomedical transport phenomena
- Chaos
- Connective tissue mechanics
- Fluid Dynamics
- Glaucoma
Fingerprint
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants
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Small molecular compounds for glaucoma therapy
Harvard University, BrightFocus Foundation
7/1/19 → 6/30/21
Project: Research project
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The Mechanical Basis of Primary Open Angle Glaucoma
Kennedy Institute - National Eye Clinic
7/1/15 → 6/30/21
Project: Research project
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Regulation and Function of Intermediate Filaments in Cell Mechanics
Adam, S. A., Gelfand, V. I., Goldman, R., Johnson, M., Kuczmarski, E. R., Ridge, K. M. & Shumaker, D. K.
National Institute of General Medical Sciences
6/15/11 → 7/31/22
Project: Research project
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Role of non-coding RNAs in glaucomatous outflow resistance dysregulation
Universität Regensburg, BrightFocus Foundation
7/1/16 → 6/30/19
Project: Research project
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Early Detection of Biomechanical Changes in Glaucoma
Northwestern Memorial Hospital
1/1/16 → 12/31/17
Project: Research project
Research Output
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In vivo imaging of Schlemm’s canal and limbal vascular network in mouse using visible-light OCT
Zhang, X., Beckmann, L., Miller, D. A., Shao, G., Cai, Z., Sun, C., Sheibani, N., Liu, X., Schuman, J., Johnson, M., Kume, T. & Zhang, H. F., Feb 2020, In: Investigative Ophthalmology and Visual Science. 61, 2, 2761682.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Targeted Delivery of Cell Softening Micelles to Schlemm's Canal Endothelial Cells for Treatment of Glaucoma
Stack, T., Vincent, M., Vahabikashi, A., Li, G., Perkumas, K. M., Stamer, W. D., Johnson, M. & Scott, E., Oct 1 2020, In: Small. 16, 43, 2004205.Research output: Contribution to journal › Article › peer-review
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Increased stiffness and flow resistance of the inner wall of Schlemm's canal in glaucomatous human eyes
Vahabikashi, A., Gelman, A., Dong, B., Gong, L., Cha, E. D. K., Schimmel, M., Tamm, E. R., Perkumas, K., Stamer, W. D., Sun, C., Zhang, H. F., Gong, H. & Johnson, M., Dec 26 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 52, p. 26555-26563 9 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Isolation and characterization of inner wall endothelial cells of the schlemm’s canal using a citrate-based polymer
Ramachandra, S., Vahabikashi, A., Johnson, M. & Ameer, G. A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness
Vahabikashi, A., Park, C. Y., Perkumas, K., Zhang, Z., Deurloo, E. K., Wu, H., Weitz, D. A., Stamer, W. D., Goldman, R. D., Fredberg, J. J. & Johnson, M., Feb 5 2019, In: Biophysical Journal. 116, 3, p. 518-529 12 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations