Grants per year
Personal profile
Research Interests
Professor Johnson is internationally known for his work on ocular biomechanics, particular with regards to the pathogenesis of glaucoma and age-related macular degeneration. Studies in his group currently involve a bioengineering approach that utilize perfusion studies, atomic force microscopy and theoretical analysis in combination with use of high-resolution morphometry and finite element modeling.
Education/Academic qualification
Mechanical Engineering, PhD, Massachusetts Institute of Technology
… → 1987
Interdisciplinary Engineering, BS, Purdue University
… → 1975
Mechanical Engineering, MS, Massachusetts Institute of Technology
Research interests keywords
- Age-Related Macular Degeneration
- Biomedical transport phenomena
- Chaos
- Connective tissue mechanics
- Fluid Dynamics
- Glaucoma
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Collaborations and top research areas from the last five years
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A Nanocarrier Platform for Targeting Schlemm's Canal Cells
Johnson, M. (PD/PI), Johnson, M. (PD/PI), Scott, E. A. (PD/PI), Scott, E. A. (PD/PI), Scott, E. A. (PD/PI), Quaggin, S. E. (Co-Investigator), Quaggin, S. E. (Co-Investigator), Thomson, B. R. (Co-Investigator), Thomson, B. R. (Co-Investigator), Zhang, H. F. (Co-Investigator) & Zhang, H. F. (Co-Investigator)
9/30/22 → 7/31/26
Project: Research project
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Small molecular compounds for glaucoma therapy
Johnson, M. (PD/PI)
Harvard University, BrightFocus Foundation
7/1/19 → 3/31/23
Project: Research project
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Regulation and Function of Intermediate Filaments in Cell Mechanics
Gelfand, V. I. (PD/PI), Goldman, R. (PD/PI), Kuczmarski, E. R. (PD/PI), Ridge, K. M. (PD/PI), Adam, S. A. (Co-Investigator), Shumaker, D. K. (Co-Investigator) & Johnson, M. (Other)
National Institute of General Medical Sciences
9/1/18 → 7/31/23
Project: Research project
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Role of non-coding RNAs in glaucomatous outflow resistance dysregulation
Johnson, M. (PD/PI)
Universität Regensburg, BrightFocus Foundation
7/1/16 → 6/30/19
Project: Research project
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Early Detection of Biomechanical Changes in Glaucoma
Johnson, M. (PD/PI) & Tanna, A. P. (Co-Investigator)
Northwestern Memorial Hospital
1/1/16 → 12/31/17
Project: Research project
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Cholesteryl Ester Transfer Protein Inhibitors and Access to the Retina in Age-Related Macular Degeneration
Curcio, C. A. & Johnson, M., Feb 8 2023, In: JAMA cardiology. 8, 2, p. 206 1 p.Research output: Contribution to journal › Letter › peer-review
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Modeling the effects of glaucoma surgery on intraocular pressure
Farrar, N., Yan, D. B. & Johnson, M., Aug 2021, In: Experimental eye research. 209, 108620.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy
Vincent, M. P., Stack, T., Vahabikashi, A., Li, G., Perkumas, K. M., Ren, R., Gong, H., Stamer, W. D., Johnson, M. & Scott, E. A., Jul 21 2021, In: ACS Applied Materials and Interfaces. 13, 28, p. 32823-32836 14 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
In vivo imaging of Schlemm’s canal and limbal vascular network in mouse using visible-light OCT
Zhang, X., Beckmann, L., Miller, D. A., Shao, G., Cai, Z., Sun, C., Sheibani, N., Liu, X., Schuman, J., Johnson, M., Kume, T. & Zhang, H. F., Feb 2020, In: Investigative Ophthalmology and Visual Science. 61, 2, 2761682.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Targeted Delivery of Cell Softening Micelles to Schlemm's Canal Endothelial Cells for Treatment of Glaucoma
Stack, T., Vincent, M., Vahabikashi, A., Li, G., Perkumas, K. M., Stamer, W. D., Johnson, M. & Scott, E., Oct 1 2020, In: Small. 16, 43, 2004205.Research output: Contribution to journal › Article › peer-review
22 Scopus citations