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Research Output 1980 2019

2019

Isolation and characterization of inner wall endothelial cells of the schlemm’s canal using a citrate-based polymer

Ramachandra, S., Vahabikashi, A., Johnson, M. & Ameer, G. A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hydrogel
Endothelial cells
Canals
Citric Acid
Glaucoma

Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness

Vahabikashi, A., Park, C. Y., Perkumas, K., Zhang, Z., Deurloo, E. K., Wu, H., Weitz, D. A., Stamer, W. D., Goldman, R., Fredberg, J. J. & Johnson, M., Feb 5 2019, In : Biophysical Journal. 116, 3, p. 518-529 12 p.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Traction
Vimentin
Microscopy
Fibroblasts
2018
3 Citations (Scopus)

Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles

Stack, T., Vahabikashi, A., Johnson, M. & Scott, E. A., Jul 1 2018, In : Journal of Biomedical Materials Research - Part A. 106, 7, p. 1771-1779 9 p.

Research output: Contribution to journalArticle

Endothelial cells
Micelles
Canals
Block copolymers
Stiffness
10 Citations (Scopus)

Rho Kinase Inhibitors as a Novel Treatment for Glaucoma and Ocular Hypertension

Tanna, A. P. & Johnson, M., Nov 1 2018, In : Ophthalmology. 125, 11, p. 1741-1756 16 p.

Research output: Contribution to journalReview article

rho-Associated Kinases
Ocular Hypertension
Glaucoma
Intraocular Pressure
latanoprost
1 Citation (Scopus)

The effect of the rate of hydrostatic pressure depressurization on cells in culture

Tworkoski, E., Glucksberg, M. R. & Johnson, M., Jan 1 2018, In : PloS one. 13, 1, e0189890.

Research output: Contribution to journalArticle

Hydrostatic Pressure
Hydrostatic pressure
cell culture
Cell Culture Techniques
Atmospheric Pressure
2017

Structure, function and pathology of Bruch's membrane

Johnson, M. & Curcio, C. A., 2017, Retina. Hinton, D. (ed.). Sixth ed. Elsevier, p. 522-543 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Citations (Scopus)

Unconventional aqueous humor outflow: A review

Johnson, M., McLaren, J. W. & Overby, D. R., May 1 2017, In : Experimental eye research. 158, p. 94-111 18 p.

Research output: Contribution to journalReview article

Aqueous Humor
Trabecular Meshwork
Sclera
Choroid
Veins
2015
36 Citations (Scopus)

Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction

Stamer, W. D., Braakman, S. T., Zhou, E. H., Ethier, C. R., Fredberg, J. J., Overby, D. R. & Johnson, M., Jan 1 2015, In : Progress in Retinal and Eye Research. 44, p. 86-98 13 p.

Research output: Contribution to journalReview article

Intraocular Pressure
Biomechanical Phenomena
Endothelium
Glaucoma
Aqueous Humor
3 Citations (Scopus)

Finite element analysis of the pressure-induced deformation of Schlemm’s canal endothelial cells

Vargas-Pinto, R., Lai, J., Gong, H., Ethier, C. R. & Johnson, M., Aug 1 2015, In : Biomechanics and Modeling in Mechanobiology. 14, 4, p. 851-863 13 p.

Research output: Contribution to journalArticle

Endothelial Cells
Finite Element Analysis
Endothelial cells
Canals
Finite Element
23 Citations (Scopus)

High-throughput screening for modulators of cellular contractile force

Park, C. Y., Zhou, E. H., Tambe, D., Chen, B., Lavoie, T., Dowell, M., Simeonov, A., Maloney, D. J., Marinkovic, A., Tschumperlin, D. J., Burger, S., Frykenberg, M., Butler, J. P., Stamer, W. D., Johnson, M., Solway, J., Fredberg, J. J. & Krishnan, R., Oct 1 2015, In : Integrative Biology (United Kingdom). 7, 10, p. 1318-1324 7 p.

Research output: Contribution to journalArticle

Glaucoma
Modulators
Screening
Asthma
Throughput

Therapeutically Targeting Disease in Glaucoma

Johnson, M. & Stamer, W. D., Jun 2015, In : Glaucoma Today. 3 p.

Research output: Contribution to journalArticle

2014
48 Citations (Scopus)

Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma

Overby, D. R., Zhou, E. H., Vargas-Pinto, R., Pedrigi, R. M., Fuchshofer, R., Braakman, S. T., Gupta, R., Perkumas, K. M., Sherwood, J. M., Vahabikashi, A., Dang, Q., Kim, J. H., Ethier, C. R., Daniel Stamer, W., Fredberg, J. J. & Johnson, M., Sep 23 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13876-13881 6 p.

Research output: Contribution to journalArticle

Biophysics
Glaucoma
Endothelial Cells
Connective Tissue Growth Factor
Aqueous Humor
10 Citations (Scopus)

Endothelial glycocalyx layer in the aqueous outflow pathway of bovine and human eyes

Yang, C. Y. C., Huynh, T., Johnson, M. & Gong, H., Nov 1 2014, In : Experimental eye research. 128, p. 27-33 7 p.

Research output: Contribution to journalArticle

Glycocalyx
Vacuoles
Vascular Endothelium
Endothelium
Alcian Blue
2013
71 Citations (Scopus)

The effect of the endothelial cell cortex on atomic force microscopy measurements

Vargas-Pinto, R., Gong, H., Vahabikashi, A. & Johnson, M., Jul 16 2013, In : Biophysical Journal. 105, 2, p. 300-309 10 p.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Endothelial Cells
Human Umbilical Vein Endothelial Cells
2012
22 Citations (Scopus)

Elastic modulus determination of normal and glaucomatous human trabecular meshwork

Russell, P. & Johnson, M., Jan 1 2012, In : Investigative Ophthalmology and Visual Science. 53, 1, 1 p.

Research output: Contribution to journalLetter

Trabecular Meshwork
Elastic Modulus
Open Angle Glaucoma
57 Citations (Scopus)

Mechanical responsiveness of the endothelial cell of Schlemm's canal: Scope, variability and its potential role in controlling aqueous humour outflow

Zhou, E. H., Krishnan, R., Stamer, W. D., Perkumas, K. M., Rajendran, K., Nabhan, J. F., Lu, Q., Fredberg, J. J. & Johnson, M., Jun 7 2012, In : Journal of the Royal Society Interface. 9, 71, p. 1144-1155 12 p.

Research output: Contribution to journalArticle

Aqueous Humor
Endothelial cells
Canals
Endothelial Cells
Sphingosines
44 Citations (Scopus)

Structure, Function, and Pathology of Bruch's Membrane

Curcio, C. A. & Johnson, M., Dec 1 2012, Retina Fifth Edition. Elsevier Inc, Vol. 1. p. 465-481 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bruch Membrane
Pathology
2011

Erratum: A biphasic, anisotropic model of the aortic wall (Journal of Biomechanical Engineering (2001) 123:2 (52-57))

Johnson, M. & Tarbell, J. M., Nov 9 2011, In : Journal of Biomechanical Engineering. 133, 10, 107001.

Research output: Contribution to journalComment/debate

25 Citations (Scopus)

Passage of low-density lipoproteins through Bruch's membrane and choroid

Cankova, Z., Huang, J. D., Kruth, H. S. & Johnson, M., Dec 1 2011, In : Experimental eye research. 93, 6, p. 947-955 9 p.

Research output: Contribution to journalArticle

Bruch Membrane
Choroid
LDL Lipoproteins
Perfusion
Retinal Pigment Epithelium

Problems for biomedical fluid mechanics and transport phenomena

Johnson, M. & Ross Ethier, C., Jan 1 2011, Cambridge University Press. 171 p.

Research output: Book/ReportBook

Biomedical engineering
Fluid mechanics
Materials properties
Mass transfer
Students
156 Citations (Scopus)

The oil spill in ageing Bruch membrane

Curcio, C. A., Johnson, M., Rudolf, M. & Huang, J. D., Dec 1 2011, In : British Journal of Ophthalmology. 95, 12, p. 1638-1645 8 p.

Research output: Contribution to journalReview article

Petroleum Pollution
Bruch Membrane
Lipids
Macular Degeneration
Lipoproteins
2010
1 Citation (Scopus)

Adequacy of exchanging the content of the anterior chamber

Johnson, M., Caro, N. & Huang, J. D., Dec 1 2010, In : Experimental Eye Research. 91, 6, p. 876-880 5 p.

Research output: Contribution to journalArticle

Anterior Chamber
Anterior Eye Segment
Buffers
Theoretical Models
Swine
103 Citations (Scopus)

Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration

Curcio, C. A., Johnson, M., Huang, J. D. & Rudolf, M., Mar 1 2010, In : Journal of Lipid Research. 51, 3, p. 451-467 17 p.

Research output: Contribution to journalReview article

Macular Degeneration
Apolipoproteins B
Lipoproteins
Aging of materials
Lipids

Biomechanics of aqueous humor outflow resistance: Encyclopedia of the Eye

Johnson, M. & Tamm, E. R., 2010, Academic Press.

Research output: Other contribution

30 Citations (Scopus)

Young's modulus of elasticity of Schlemm's canal endothelial cells

Zeng, D., Juzkiw, T., Read, A. T., Chan, D. W. H., Glucksberg, M. R., Ethier, C. R. & Johnson, M., Feb 1 2010, In : Biomechanics and Modeling in Mechanobiology. 9, 1, p. 19-33 15 p.

Research output: Contribution to journalArticle

Modulus of elasticity
Endothelial Cells
Elastic Modulus
Endothelial cells
Young's Modulus
2009
153 Citations (Scopus)

Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins

Curcio, C. A., Johnson, M., Huang, J. D. & Rudolf, M., Nov 1 2009, In : Progress in Retinal and Eye Research. 28, 6, p. 393-422 30 p.

Research output: Contribution to journalReview article

Macular Degeneration
Apolipoproteins B
Lipoproteins
Retinal Pigment Epithelium
Lipids

Douglas H. Johnson: A tribute

Johnson, M. & Fautsch, M. P., Apr 30 2009, In : Experimental Eye Research. 88, 4, p. 620-630 11 p.

Research output: Contribution to journalReview article

21st Century History
20th Century History
Open Angle Glaucoma
Ophthalmology
Biomedical Research

Response to "Merchant and Heys, Effects of Variable Permeability on Aqueous Humor Outflow, Applied Mathematics and Computation 196 (2008) 371-380"

Overby, D. R., Ruberti, J. W., Gong, H., Freddo, T. F. & Johnson, M., May 1 2009, In : Applied Mathematics and Computation. 211, 1, p. 251-252 2 p.

Research output: Contribution to journalArticle

Applied mathematics
Permeability
Porous materials
Tissue
Porous Media Flow
114 Citations (Scopus)

The changing paradigm of outflow resistance generation: Towards synergistic models of the JCT and inner wall endothelium

Overby, D. R., Stamer, W. D. & Johnson, M., Apr 30 2009, In : Experimental eye research. 88, 4, p. 656-670 15 p.

Research output: Contribution to journalReview article

Connective Tissue
Endothelium
Aqueous Humor
Hydrodynamics
Intraocular Pressure
2008
3 Citations (Scopus)

Chapter 6 Aqueous Humor Outflow Resistance

Freddo, T. F. & Johnson, M., Oct 7 2008, The Eye's Aqueous Humor. p. 161-192 32 p. (Current Topics in Membranes; vol. 62).

Research output: Chapter in Book/Report/Conference proceedingChapter

Aqueous Humor
Trabecular Meshwork
Disease Resistance
Frustration
Venous Pressure

Conventional Aqueous Humor Outflow

Freddo, T. F. & Johnson, M., 2008, The Eye’s Aqueous Humor. Civan, M. (ed.). Elsevier

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Citations (Scopus)

Effects of particulates and lipids on the hydraulic conductivity of Matrigel

McCarty, W. J., Chimento, M. F., Curcio, C. A. & Johnson, M., Aug 1 2008, In : Journal of Applied Physiology. 105, 2, p. 621-628 8 p.

Research output: Contribution to journalArticle

Nanospheres
LDL Lipoproteins
Latex
Lipids
Connective Tissue
33 Citations (Scopus)

Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane

Huang, J. D., Curcio, C. A. & Johnson, M., Jun 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 6, p. 2721-2727 7 p.

Research output: Contribution to journalArticle

Bruch Membrane
Lipoproteins
Retinal Pigment Epithelium
Lipids
Particle Size
2007
61 Citations (Scopus)

Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch

Huang, J. D., Presley, J. B., Chimento, M. F., Curcio, C. A. & Johnson, M., Aug 1 2007, In : Experimental eye research. 85, 2, p. 202-218 17 p.

Research output: Contribution to journalArticle

Bruch Membrane
Lipoproteins
Lipids
Retinal Pigment Epithelium
Macular Degeneration
24 Citations (Scopus)

Comparison of morphology of human macular and peripheral Bruch's membrane in older eyes

Johnson, M., Dabholkar, A., Huang, J. D., Presley, J. B., Chimento, M. F. & Curcio, C. A., Sep 1 2007, In : Current eye research. 32, 9, p. 791-799 9 p.

Research output: Contribution to journalArticle

Bruch Membrane
Lipoproteins
Osmium
Lipids
Tannins
10 Citations (Scopus)

The hydraulic conductivity of Matrigel™

Mccarty, W. J. & Johnson, M., Dec 1 2007, In : Biorheology. 44, 5-6, p. 303-317 15 p.

Research output: Contribution to journalArticle

Gels
Pressure
Perfusion
matrigel
2006
62 Citations (Scopus)

Aqueous humor outflow: What do we know? Where will it lead us?

Fautsch, M. P., Johnson, D. H., Acott, T. S., Aihara, M., Bhattacharya, S. K., Borrás, T., Camras, C. B., Civan, M. M., Clark, A. F., Crosson, C. E., Crowston, J. G., Epstein, D., Ethier, C. R., Freddo, T. F., Gong, H., Gonzalez, P., John, S. W., Johnson, M., Kaufman, P. L., Knepper, P. A. & 30 others, Lindsey, J. D., Lütjen-Drecoll, E., Peters, D. M., Rao, P. V., Roy, S., Russell, P., Stamer, D., Tamm, E. R., Toris, C. B., Weinreb, R. N., Yue, B., Bornstein, P., Davies, P. F., Geiger, B., Kerjaschki, D., Mitchell, J., Schneeberger, E., Stitt, A., Zawieja, D. C., Bosworth, C., Grunden, J., Kim, E., Kopczynski, C., Krauss, A., Panjwani, N., Paterson, C., Prasanna, G., Rhee, D., Whitlock, A. & WuDunn, D., Oct 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 10, p. 4181-4187 7 p.

Research output: Contribution to journalArticle

Aqueous Humor
Vacuoles
Terminology
Endothelium
Culture Media
244 Citations (Scopus)

What controls aqueous humour outflow resistance?

Johnson, M., Apr 1 2006, In : Experimental eye research. 82, 4, p. 545-557 13 p.

Research output: Contribution to journalReview article

Aqueous Humor
Endothelium
Vacuoles
Basement Membrane
Glaucoma
2005
14 Citations (Scopus)

Optical monitoring of bubble size and shape in a pulsating bubble surfactometer

Seurynck, S. L., Brown, N. J., Wu, C. W., Germino, K. W., Kohlmeir, E. K., Ingenito, E. P., Glucksberg, M. R., Barren, A. E. & Johnson, M., Aug 1 2005, In : Journal of Applied Physiology. 99, 2, p. 624-633 10 p.

Research output: Contribution to journalArticle

Surface Tension
Surface-Active Agents
1,2-Dipalmitoylphosphatidylcholine
Software
Lung
14 Citations (Scopus)

Studies on depth-of-field effects in microscopy supported by numerical simulations

Overby, D. R. & Johnson, M., Dec 1 2005, In : Journal of Microscopy. 220, 3, p. 176-189 14 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Microscopy
2004
180 Citations (Scopus)

Ocular biomechanics and biotransport

Ethier, C. R., Johnson, M. & Ruberti, J., Sep 22 2004, In : Annual Review of Biomedical Engineering. 6, p. 249-273 25 p.

Research output: Contribution to journalReview article

Biomechanics
Biomechanical Phenomena
Presbyopia
Solute transport
Fluids
2003

A stereologic technique to quantify the specific hydraulic conductivity of extracellular matrix using electron microscopy

Overby, D. & Johnson, M., Jun 2 2003, Computational Fluid and Solid Mechanics 2003. Elsevier Inc, p. 1790-1793 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hydraulic conductivity
Specific surface area
Electron microscopy
Porosity
Electrons
91 Citations (Scopus)

Quick-freeze/deep-etch visualization of age-related lipid accumulation in Bruch's membrane

Ruberti, J. W., Curcio, C. A., Millican, C. L., Menco, B. P. M., Huang, J. D. & Johnson, M., Apr 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 4, p. 1753-1759 7 p.

Research output: Contribution to journalArticle

Bruch Membrane
Retinal Pigment Epithelium
Lipids
Transmission Electron Microscopy
Basement Membrane
2002
57 Citations (Scopus)

A new view of the human trabecular meshwork using quick-freeze, deep-etch electron microscopy

Gong, H., Ruberti, J., Overby, D., Johnson, M. & Freddo, T. F., Jan 1 2002, In : Experimental Eye Research. 75, 3, p. 347-358 12 p.

Research output: Contribution to journalArticle

Trabecular Meshwork
Electron Microscopy
Basement Membrane
Electrons
Extracellular Matrix
28 Citations (Scopus)

Glaucoma surgery and aqueous outflow: How does nonpenetrating glaucoma surgery work?

Johnson, D. H. & Johnson, M., Jan 1 2002, In : Archives of Ophthalmology. 120, 1, p. 67-70 4 p.

Research output: Contribution to journalEditorial

Ophthalmologic Surgical Procedures
Trabecular Meshwork
Aqueous Humor
Intraocular Pressure
Glaucoma
59 Citations (Scopus)

The mechanism of increasing outflow facility during washout in the bovine eye

Overby, D., Gong, H., Qiu, G., Freddo, T. F. & Johnson, M., Nov 1 2002, In : Investigative Ophthalmology and Visual Science. 43, 11, p. 3455-3464 10 p.

Research output: Contribution to journalArticle

Connective Tissue
arginyl-glycyl-glutamic acid
Perfusion
Aqueous Humor
Anterior Chamber
71 Citations (Scopus)

The pore density in the inner wall endothelium of Schlemm's canal of glaucomatous eyes

Johnson, M., Chan, D., Read, A. T., Christensen, C., Sit, A. & Ethier, C. R., Sep 1 2002, In : Investigative Ophthalmology and Visual Science. 43, 9, p. 2950-2955 6 p.

Research output: Contribution to journalArticle

Endothelium
Fixatives
Electron Scanning Microscopy
Aqueous Humor
Porosity
2001
22 Citations (Scopus)

A biphasic, anisotropic model of the aortic wall

Johnson, M. & Tarbell, J. M., Jan 1 2001, In : Journal of Biomechanical Engineering. 123, 1, p. 52-57 6 p.

Research output: Contribution to journalArticle

Hydraulic conductivity
Pressure
Aorta
Dilatation
Perfusion

Aqueous outflow and glaucoma surgery

Johnson, D. H., 2001, In : Ophthalmo-Chirurgie. 13, p. 88-89

Research output: Contribution to journalArticle