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Research Output 1980 2019

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2019

Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness

Vahabikashi, A., Park, C. Y., Perkumas, K., Zhang, Z., Deurloo, E. K., Wu, H., Weitz, D. A., Stamer, W. D., Goldman, R., Fredberg, J. J. & Johnson, M., Feb 5 2019, In : Biophysical Journal. 116, 3, p. 518-529 12 p.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Traction
Vimentin
Microscopy
Fibroblasts
2018
3 Citations (Scopus)

Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles

Stack, T., Vahabikashi, A., Johnson, M. & Scott, E. A., Jul 1 2018, In : Journal of Biomedical Materials Research - Part A. 106, 7, p. 1771-1779 9 p.

Research output: Contribution to journalArticle

Endothelial cells
Micelles
Canals
Block copolymers
Stiffness

The effect of the rate of hydrostatic pressure depressurization on cells in culture

Tworkoski, E., Glucksberg, M. R. & Johnson, M., Jan 1 2018, In : PloS one. 13, 1, e0189890.

Research output: Contribution to journalArticle

Hydrostatic Pressure
Hydrostatic pressure
cell culture
Cell Culture Techniques
Atmospheric Pressure
2015
3 Citations (Scopus)

Finite element analysis of the pressure-induced deformation of Schlemm’s canal endothelial cells

Vargas-Pinto, R., Lai, J., Gong, H., Ethier, C. R. & Johnson, M., Aug 1 2015, In : Biomechanics and Modeling in Mechanobiology. 14, 4, p. 851-863 13 p.

Research output: Contribution to journalArticle

Endothelial Cells
Finite Element Analysis
Endothelial cells
Canals
Finite Element
22 Citations (Scopus)

High-throughput screening for modulators of cellular contractile force

Park, C. Y., Zhou, E. H., Tambe, D., Chen, B., Lavoie, T., Dowell, M., Simeonov, A., Maloney, D. J., Marinkovic, A., Tschumperlin, D. J., Burger, S., Frykenberg, M., Butler, J. P., Stamer, W. D., Johnson, M., Solway, J., Fredberg, J. J. & Krishnan, R., Oct 1 2015, In : Integrative Biology (United Kingdom). 7, 10, p. 1318-1324 7 p.

Research output: Contribution to journalArticle

Glaucoma
Modulators
Screening
Asthma
Throughput

Therapeutically Targeting Disease in Glaucoma

Johnson, M. & Stamer, W. D., Jun 2015, In : Glaucoma Today. 3 p.

Research output: Contribution to journalArticle

2014
48 Citations (Scopus)

Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma

Overby, D. R., Zhou, E. H., Vargas-Pinto, R., Pedrigi, R. M., Fuchshofer, R., Braakman, S. T., Gupta, R., Perkumas, K. M., Sherwood, J. M., Vahabikashi, A., Dang, Q., Kim, J. H., Ethier, C. R., Daniel Stamer, W., Fredberg, J. J. & Johnson, M., Sep 23 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13876-13881 6 p.

Research output: Contribution to journalArticle

Biophysics
Glaucoma
Endothelial Cells
Connective Tissue Growth Factor
Aqueous Humor
10 Citations (Scopus)

Endothelial glycocalyx layer in the aqueous outflow pathway of bovine and human eyes

Yang, C. Y. C., Huynh, T., Johnson, M. & Gong, H., Nov 1 2014, In : Experimental eye research. 128, p. 27-33 7 p.

Research output: Contribution to journalArticle

Glycocalyx
Vacuoles
Vascular Endothelium
Endothelium
Alcian Blue
2013
69 Citations (Scopus)

The effect of the endothelial cell cortex on atomic force microscopy measurements

Vargas-Pinto, R., Gong, H., Vahabikashi, A. & Johnson, M., Jul 16 2013, In : Biophysical Journal. 105, 2, p. 300-309 10 p.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Endothelial Cells
Human Umbilical Vein Endothelial Cells
2012
57 Citations (Scopus)

Mechanical responsiveness of the endothelial cell of Schlemm's canal: Scope, variability and its potential role in controlling aqueous humour outflow

Zhou, E. H., Krishnan, R., Stamer, W. D., Perkumas, K. M., Rajendran, K., Nabhan, J. F., Lu, Q., Fredberg, J. J. & Johnson, M., Jun 7 2012, In : Journal of the Royal Society Interface. 9, 71, p. 1144-1155 12 p.

Research output: Contribution to journalArticle

Aqueous Humor
Endothelial cells
Canals
Endothelial Cells
Sphingosines
2011
24 Citations (Scopus)

Passage of low-density lipoproteins through Bruch's membrane and choroid

Cankova, Z., Huang, J. D., Kruth, H. S. & Johnson, M., Dec 1 2011, In : Experimental eye research. 93, 6, p. 947-955 9 p.

Research output: Contribution to journalArticle

Bruch Membrane
Choroid
LDL Lipoproteins
Perfusion
Retinal Pigment Epithelium
2010
1 Citation (Scopus)

Adequacy of exchanging the content of the anterior chamber

Johnson, M., Caro, N. & Huang, J. D., Dec 1 2010, In : Experimental Eye Research. 91, 6, p. 876-880 5 p.

Research output: Contribution to journalArticle

Anterior Chamber
Anterior Eye Segment
Buffers
Theoretical Models
Swine
30 Citations (Scopus)

Young's modulus of elasticity of Schlemm's canal endothelial cells

Zeng, D., Juzkiw, T., Read, A. T., Chan, D. W. H., Glucksberg, M. R., Ethier, C. R. & Johnson, M., Feb 1 2010, In : Biomechanics and Modeling in Mechanobiology. 9, 1, p. 19-33 15 p.

Research output: Contribution to journalArticle

Modulus of elasticity
Endothelial Cells
Elastic Modulus
Endothelial cells
Young's Modulus
2009

Response to "Merchant and Heys, Effects of Variable Permeability on Aqueous Humor Outflow, Applied Mathematics and Computation 196 (2008) 371-380"

Overby, D. R., Ruberti, J. W., Gong, H., Freddo, T. F. & Johnson, M., May 1 2009, In : Applied Mathematics and Computation. 211, 1, p. 251-252 2 p.

Research output: Contribution to journalArticle

Applied mathematics
Permeability
Porous materials
Tissue
Porous Media Flow
2008
13 Citations (Scopus)

Effects of particulates and lipids on the hydraulic conductivity of Matrigel

McCarty, W. J., Chimento, M. F., Curcio, C. A. & Johnson, M., Aug 1 2008, In : Journal of Applied Physiology. 105, 2, p. 621-628 8 p.

Research output: Contribution to journalArticle

Nanospheres
LDL Lipoproteins
Latex
Lipids
Connective Tissue
33 Citations (Scopus)

Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane

Huang, J. D., Curcio, C. A. & Johnson, M., Jun 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 6, p. 2721-2727 7 p.

Research output: Contribution to journalArticle

Bruch Membrane
Lipoproteins
Retinal Pigment Epithelium
Lipids
Particle Size
2007
61 Citations (Scopus)

Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch

Huang, J. D., Presley, J. B., Chimento, M. F., Curcio, C. A. & Johnson, M., Aug 1 2007, In : Experimental eye research. 85, 2, p. 202-218 17 p.

Research output: Contribution to journalArticle

Bruch Membrane
Lipoproteins
Lipids
Retinal Pigment Epithelium
Macular Degeneration
24 Citations (Scopus)

Comparison of morphology of human macular and peripheral Bruch's membrane in older eyes

Johnson, M., Dabholkar, A., Huang, J. D., Presley, J. B., Chimento, M. F. & Curcio, C. A., Sep 1 2007, In : Current eye research. 32, 9, p. 791-799 9 p.

Research output: Contribution to journalArticle

Bruch Membrane
Lipoproteins
Osmium
Lipids
Tannins
10 Citations (Scopus)

The hydraulic conductivity of Matrigel™

Mccarty, W. J. & Johnson, M., Dec 1 2007, In : Biorheology. 44, 5-6, p. 303-317 15 p.

Research output: Contribution to journalArticle

Gels
Pressure
Perfusion
matrigel
2006
59 Citations (Scopus)

Aqueous humor outflow: What do we know? Where will it lead us?

Fautsch, M. P., Johnson, D. H., Acott, T. S., Aihara, M., Bhattacharya, S. K., Borrás, T., Camras, C. B., Civan, M. M., Clark, A. F., Crosson, C. E., Crowston, J. G., Epstein, D., Ethier, C. R., Freddo, T. F., Gong, H., Gonzalez, P., John, S. W., Johnson, M., Kaufman, P. L., Knepper, P. A. & 30 others, Lindsey, J. D., Lütjen-Drecoll, E., Peters, D. M., Rao, P. V., Roy, S., Russell, P., Stamer, D., Tamm, E. R., Toris, C. B., Weinreb, R. N., Yue, B., Bornstein, P., Davies, P. F., Geiger, B., Kerjaschki, D., Mitchell, J., Schneeberger, E., Stitt, A., Zawieja, D. C., Bosworth, C., Grunden, J., Kim, E., Kopczynski, C., Krauss, A., Panjwani, N., Paterson, C., Prasanna, G., Rhee, D., Whitlock, A. & WuDunn, D., Oct 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 10, p. 4181-4187 7 p.

Research output: Contribution to journalArticle

Aqueous Humor
Vacuoles
Terminology
Endothelium
Culture Media
2005
14 Citations (Scopus)

Optical monitoring of bubble size and shape in a pulsating bubble surfactometer

Seurynck, S. L., Brown, N. J., Wu, C. W., Germino, K. W., Kohlmeir, E. K., Ingenito, E. P., Glucksberg, M. R., Barren, A. E. & Johnson, M., Aug 1 2005, In : Journal of Applied Physiology. 99, 2, p. 624-633 10 p.

Research output: Contribution to journalArticle

Surface Tension
Surface-Active Agents
1,2-Dipalmitoylphosphatidylcholine
Software
Lung
14 Citations (Scopus)

Studies on depth-of-field effects in microscopy supported by numerical simulations

Overby, D. R. & Johnson, M., Dec 1 2005, In : Journal of Microscopy. 220, 3, p. 176-189 14 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Microscopy
2003
91 Citations (Scopus)

Quick-freeze/deep-etch visualization of age-related lipid accumulation in Bruch's membrane

Ruberti, J. W., Curcio, C. A., Millican, C. L., Menco, B. P. M., Huang, J. D. & Johnson, M., Apr 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 4, p. 1753-1759 7 p.

Research output: Contribution to journalArticle

Bruch Membrane
Retinal Pigment Epithelium
Lipids
Transmission Electron Microscopy
Basement Membrane
2002
56 Citations (Scopus)

A new view of the human trabecular meshwork using quick-freeze, deep-etch electron microscopy

Gong, H., Ruberti, J., Overby, D., Johnson, M. & Freddo, T. F., Jan 1 2002, In : Experimental Eye Research. 75, 3, p. 347-358 12 p.

Research output: Contribution to journalArticle

Trabecular Meshwork
Electron Microscopy
Basement Membrane
Electrons
Extracellular Matrix
59 Citations (Scopus)

The mechanism of increasing outflow facility during washout in the bovine eye

Overby, D., Gong, H., Qiu, G., Freddo, T. F. & Johnson, M., Nov 1 2002, In : Investigative Ophthalmology and Visual Science. 43, 11, p. 3455-3464 10 p.

Research output: Contribution to journalArticle

Connective Tissue
arginyl-glycyl-glutamic acid
Perfusion
Aqueous Humor
Anterior Chamber
71 Citations (Scopus)

The pore density in the inner wall endothelium of Schlemm's canal of glaucomatous eyes

Johnson, M., Chan, D., Read, A. T., Christensen, C., Sit, A. & Ethier, C. R., Sep 1 2002, In : Investigative Ophthalmology and Visual Science. 43, 9, p. 2950-2955 6 p.

Research output: Contribution to journalArticle

Endothelium
Fixatives
Electron Scanning Microscopy
Aqueous Humor
Porosity
2001
22 Citations (Scopus)

A biphasic, anisotropic model of the aortic wall

Johnson, M. & Tarbell, J. M., Jan 1 2001, In : Journal of Biomechanical Engineering. 123, 1, p. 52-57 6 p.

Research output: Contribution to journalArticle

Hydraulic conductivity
Pressure
Aorta
Dilatation
Perfusion

Aqueous outflow and glaucoma surgery

Johnson, D. H., 2001, In : Ophthalmo-Chirurgie. 13, p. 88-89

Research output: Contribution to journalArticle

17 Citations (Scopus)

Dynamic behavior of lung surfactant

Morris, J., Ingenito, E. P., Mark, L., Kamm, R. D. & Johnson, M., Mar 20 2001, In : Journal of Biomechanical Engineering. 123, 1, p. 106-113 8 p.

Research output: Contribution to journalArticle

Surface-Active Agents
Surface active agents
Lung
Adsorption
Desorption
104 Citations (Scopus)

How does nonpenetrating glaucoma surgery work? Aqueous outflow resistance and glaucoma surgery

Johnson, D. H., Johnson, M. & Camras, C., Jan 1 2001, In : Journal of Glaucoma. 10, 1, p. 55-67 13 p.

Research output: Contribution to journalArticle

Glaucoma
Trabecular Meshwork
Drainage
Rupture
Theoretical Models
25 Citations (Scopus)

Specific hydraulic conductivity of corneal stroma as seen by quick-freeze/deep-etch

Overby, D., Ruberti, J., Gong, H., Freddo, T. F. & Johnson, M., May 9 2001, In : Journal of Biomechanical Engineering. 123, 2, p. 154-161 8 p.

Research output: Contribution to journalArticle

Corneal Stroma
Hydraulic conductivity
Connective Tissue
Uncertainty
Tissue
74 Citations (Scopus)

The presence and properties of myocilin in the aqueous humor

Russell, P., Tamm, E. R., Grehn, F. J., Picht, G. & Johnson, M., Apr 23 2001, In : Investigative Ophthalmology and Visual Science. 42, 5, p. 983-986 4 p.

Research output: Contribution to journalArticle

Aqueous Humor
Western Blotting
Proteins
Haplorhini
trabecular meshwork-induced glucocorticoid response protein
2000

Stereological corrections of quantitative morphology

Overby, D. & Johnson, M., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Numerical models
Porosity
1999
45 Citations (Scopus)

Biophysical characterization and modeling of lung surfactant components

Ingenito, E. P., Mark, L., Morris, J., Espinosa, F. F., Kamm, R. D. & Johnson, M., Jan 1 1999, In : Journal of Applied Physiology. 86, 5, p. 1702-1714 13 p.

Research output: Contribution to journalArticle

Surface-Active Agents
Apoproteins
Lung
Phospholipids
Surface Tension
1998
2 Citations (Scopus)

An operational test for distinguishing between complicated and chaotic behavior in deterministic systems

Johnson, M. & Habyarimana, J., Jan 1 1998, In : Physica D: Nonlinear Phenomena. 116, 3-4, p. 289-300 12 p.

Research output: Contribution to journalArticle

autocorrelation
chaos
trajectories
exponents
orbits
63 Citations (Scopus)

Two pore types in the inner-wall endothelium of Schlemm's canal

Ethier, C. R., Coloma, F. M., Sit, A. J. & Johnson, M., Oct 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 11, p. 2041-2048 8 p.

Research output: Contribution to journalArticle

Endothelium
Tissue Fixation
Histological Techniques
Pressure
Fixatives
1997

Analysis of hydraulic conductivity of corneal stroma using quick-freeze/deep-etch

Johnson, M., Gong, H., Kamm, R. D. & Freddo, T. F., Dec 1 1997, In : American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 35, p. 219-220 2 p.

Research output: Contribution to journalArticle

Ophthalmology
Hydraulic conductivity
Porosity
Proteins
54 Citations (Scopus)

Factors affecting the pores of the inner wall endothelium of Schlemm's canal

Sit, A. J., Coloma, F. M., Ethier, C. R. & Johnson, M., Aug 12 1997, In : Investigative Ophthalmology and Visual Science. 38, 8, p. 1517-1525 9 p.

Research output: Contribution to journalArticle

Endothelium
Fixatives
Pressure
Electron Scanning Microscopy
Perfusion
1 Citation (Scopus)

Hydraulic conductivity of juxtacanalicular connective tissue using quick-freeze/deep-ETCH

Gongi, H., Brown, K., Johnson, M., Kamm, R. D. & Freddo, T. F., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4

Research output: Contribution to journalArticle

Connective Tissue
Corneal Stroma
Trabecular Meshwork
Gels
Hydrodynamics
36 Citations (Scopus)

Interendothelial junctions in normal human schlemm's canal respond to changes in pressure

Ye, W., Gong, H., Sit, A., Johnson, M. & Freddo, T. F., Nov 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 12, p. 2460-2468 9 p.

Research output: Contribution to journalArticle

Endothelial Cells
Pressure
Perfusion
Immersion
Tight Junctions
32 Citations (Scopus)

Intraocular pressure and outflow facility are unchanged following acute and chronic intracameral chondroitinase ABC and hyaluronidase in monkeys

Hubbard, W. C., Johnson, M., Gong, H., Gabelt, B. T., Peterson, J. A., Sawhney, R., Freddo, T. & Kaufman, P. L., Jan 1 1997, In : Experimental eye research. 65, 2, p. 177-190 14 p.

Research output: Contribution to journalArticle

Chondroitin ABC Lyase
Hyaluronoglucosaminidase
Intraocular Pressure
Haplorhini
Chondroitinases and Chondroitin Lyases
14 Citations (Scopus)

The non-uniform distribution of albumin in human and bovine cornea

Gong, H., Johnson, M., Ye, W., Kamm, R. D. & Freddo, T. F., Jan 1 1997, In : Experimental eye research. 65, 6, p. 747-756 10 p.

Research output: Contribution to journalArticle

Cornea
Albumins
Corneal Stroma
Limbus Corneae
Staining and Labeling
22 Citations (Scopus)

The role of soluble proteins in generating aqueous outflow resistance in the bovine and human eye

Sit, A. J., Gong, H., Ritter, N., Freddo, T. F., Kamm, R. & Johnson, M., Jan 1 1997, In : Experimental eye research. 64, 5, p. 813-821 9 p.

Research output: Contribution to journalArticle

Proteins
Eye Proteins
Buffers
Globulins
Serum
1996

IOP and outflow facility are unchanged following acute and chronic intracameral chondroitinase and hyaluronidase in monkeys

Hubbard, W. C., Johnson, M., Gong, H., Gabelt, B. T., Tian, B., Peterson, J. A., Sawhney, R., Freddo, T. & Kaufman, P. L., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Chondroitinases and Chondroitin Lyases
Hyaluronoglucosaminidase
Haplorhini
Trabecular Meshwork
A73025
23 Citations (Scopus)

The effect of aging and pressure on the specific hydraulic conductivity of the aortic wall

Whale, M. D., Grodzinsky, A. J. & Johnson, M., Jan 1 1996, In : Biorheology. 33, 1, p. 17-44 28 p.

Research output: Contribution to journalArticle

Pressure
Aorta
Perfusion
Human Development
Hydrodynamics
1994
43 Citations (Scopus)

Age-related changes of scleral hydration and sulfated glycosaminoglycans

Brown, C. T., Vural, M., Johnson, M. & Trinkaus-Randall, V., Dec 16 1994, In : Mechanisms of Ageing and Development. 77, 2, p. 97-107 11 p.

Research output: Contribution to journalArticle

A73025
Glycosaminoglycans
Sclera
Dermatan Sulfate
Chondroitin Sulfates
82 Citations (Scopus)

Dynamic surface tension of surfactant TA: Experiments and theory

Otis, D. R., Ingenito, E. P., Kamm, R. D. & Johnson, M., Jan 1 1994, In : Journal of Applied Physiology. 77, 6, p. 2681-2688 8 p.

Research output: Contribution to journalArticle

Surface Tension
Surface-Active Agents
Adsorption
Suspensions
beractant
1993
117 Citations (Scopus)

Role of pulmonary surfactant in airway closure: A computational study

Otis, D. R., Johnson, M., Pedley, T. J. & Kamm, R. D., Jan 1 1993, In : Journal of Applied Physiology. 75, 3, p. 1323-1333 11 p.

Research output: Contribution to journalArticle

Pulmonary Surfactants
Surface Tension
Surface-Active Agents
Pressure
40 Citations (Scopus)

Serum proteins and aqueous outflow resistance in bovine eyes

Johnson, M., Gong, H., Freddo, T. F., Ritter, N. & Kamm, R., Dec 1 1993, In : Investigative Ophthalmology and Visual Science. 34, 13, p. 3549-3557 9 p.

Research output: Contribution to journalArticle

Blood Proteins
Trabecular Meshwork
Buffers
Aqueous Humor
Perfusion
1992
51 Citations (Scopus)

Age-related changes of sulfated proteoglycans in the normal human trabecular meshwork

Gong, H., Freddo, T. F. & Johnson, M., Jan 1 1992, In : Experimental eye research. 55, 5, p. 691-709 19 p.

Research output: Contribution to journalArticle

Trabecular Meshwork
Proteoglycans
Collagen
Basement Membrane
Fibril-Associated Collagens