• 26038 Citations
19982023
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Personal profile

Research Interests

Novel biomarkers of endocrine resistance in breast cancer. Circulating tumor cells (CTCs) and ctDNA. Drug development with focus on endocrine therapy.

Management of breast cancer with particular focus on inflammatory breast cancer (IBC), Locally Advanced Breast Cancer (LABC) and Metastatic Breast Cancer (MBC). Expertise in new endocrine therapies for hormone-receptor positive MBC.

Training Experience

1994Internship, Cabrini Medical Center, New York, NY
1996Residency, Cabrini Medical Center, New York, NY
1998Fellowship, University of Texas/MD Anderson Cancer Center

Education/Academic qualification

MD, University La Sapienza, Rome, Italy

… → 1986

Research interests

  • Breast Cancer
  • Cancer Genetics
  • Chemotherapy
  • Molecular Diagnostics
  • Oncology

Fingerprint Dive into the research topics where Massimo Cristofanilli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Breast Neoplasms Medicine & Life Sciences
Inflammatory Breast Neoplasms Medicine & Life Sciences
Circulating Neoplastic Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Neoplasm Metastasis Medicine & Life Sciences
Survival Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2015 2023

Research Output 1998 2020

Corrigendum to “Efficacy + safety of palbociclib (P) in patients (pts) ≤50 y with hormone receptor‒positive (HR+)/human epidermal growth factor receptor 2‒negative (HER2–) advanced breast cancer (ABC): Subgroup analysis of 2 randomized phase 3 studies” (The Breast (2018) 41(S1) (S11–S12), (S0960977618301760), (10.1016/j.breast.2018.08.033))

Cristofanilli, M., Harbeck, N., Rugo, H. S., Castrellon, A., Joy, A. A., Verma, S., Im, S. A., Iyer, S., Puyana Theall, K., Gauthier, E., Huang, X., Bartlett, C. H., Loibl, S. & Finn, R. S., Feb 2020, In : Breast. 49, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Epidermal Growth Factor Receptor
Names
Breast
Hormones
Breast Neoplasms
7 Citations (Scopus)

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

Formisano, L., Lu, Y., Servetto, A., Hanker, A. B., Jansen, V. M., Bauer, J. A., Sudhan, D. R., Guerrero-Zotano, A. L., Croessmann, S., Guo, Y., Ericsson, P. G., Lee, K. M., Nixon, M. J., Schwarz, L. J., Sanders, M. E., Dugger, T. C., Cruz, M. R., Behdad, A., Cristofanilli, M., Bardia, A. & 11 others, O’Shaughnessy, J., Nagy, R. J., Lanman, R. B., Solovieff, N., He, W., Miller, M., Su, F., Shyr, Y., Mayer, I. A., Balko, J. M. & Arteaga, C. L., Dec 1 2019, In : Nature communications. 10, 1, 1373.

Research output: Contribution to journalArticle

Open Access
breast
inhibitors
cancer
Breast Neoplasms
Protein-Tyrosine Kinases
1 Citation (Scopus)

A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy

Zhou, Z., Feng, Z., Hu, D., Yang, P., Gur, M., Bahar, I., Cristofanilli, M., Gradishar, W. J., Xie, X. Q. & Wan, Y., Jun 2019, In : EBioMedicine. 44, p. 98-111 14 p.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Methylation
Tumors
Molecules
Genes

A novel strategy to block mitotic progression for targeted therapy

Chi, J. J., Li, H., Zhou, Z., Izquierdo-Ferrer, J., Xue, Y., Wavelet, C. M., Schiltz, G. E., Zhang, B., Cristofanilli, M., Lu, X., Bahar, I. & Wan, Y., Nov 2019, In : EBioMedicine. 49, p. 40-54 15 p.

Research output: Contribution to journalArticle

Open Access
Degradation
Tumors
Cells
Neoplasms
Breast Neoplasms

Association between circulating tumor cells and peripheral blood monocytes in metastatic breast cancer

De Giorgi, U., Mego, M., Scarpi, E., Giordano, A., Giuliano, M., Valero, V., Alvarez, R. H., Ueno, N. T., Cristofanilli, M. & Reuben, J. M., Aug 1 2019, In : Therapeutic Advances in Medical Oncology. 11

Research output: Contribution to journalArticle

Open Access
Circulating Neoplastic Cells
Monocytes
Breast Neoplasms
Inflammation
Neoplasms