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Matt Clutter

  • 536 Citations
20052024

Research output per year

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Grants

Development of Novel MNK Inhibitors for Treating Glioblastoma

Clutter, M., Eckerdt, F. D., Horbinski, C. M., James, C. D., Mishra, R. K., Platanias, L. C. & Schiltz, G. E.

National Institute of Neurological Disorders and Stroke

9/1/19 → 6/30/24

Project: Research project

    • Harnessing Druggable Synthetic Lethal Interactions in Triple-Negative Breast Cancer with Elevated MYC Expression

    Clutter, M., Horiuchi, D., Mendillo, M. L., Vasilopoulos, A. & Santa-Maria, C. A.

    U.S. Army Medical Research and Materiel Command

    4/1/18 → 3/31/21

    Project: Research project

    • Discovery of novel small molecule antidepressants

    Clutter, M., Mishra, R. K. & Schiltz, G. E.

    Vanderbilt University, National Institute of Mental Health

    2/1/18 → 1/31/20

    Project: Research project

    • Subproject for Gary Schiltz for the project titled, "Discovery of novel small molecule antidepressants".

    Clutter, M., Luan, C., Mishra, R. K. & Schiltz, G. E.

    National Institute of Mental Health

    4/15/16 → 1/31/19

    Project: Research project

    • Discovery of novel small molecule antidepressants

    Chetkovich, D. M., Clutter, M., Han, Y., Luan, C., Mishra, R. K. & Schiltz, G. E.

    National Institute of Mental Health

    4/15/16 → 1/31/19

    Project: Research project

    • Research Output

    • 536 Citations
    • 13 Article
    • 1 Review article

    Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening

    Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In : Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.

    Research output: Contribution to journal › Article

    • Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential (ESP) Charges

    Mishra, R. K., Deibler, K. K., Clutter, M. R., Vagadia, P. P., O'Connor, M., Schiltz, G. E., Bergan, R. & Scheidt, K. A., Jan 1 2019, (Accepted/In press) In : Journal of Chemical Information and Modeling.

    Research output: Contribution to journal › Article

    • Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

    Deibler, K. K., Schiltz, G. E., Clutter, M., Mishra, R. K., Vagadia, P. P., O'Connor, M., George, M. D., Gordon, R., Fowler, G., Bergan, R. & Scheidt, K. A., Mar 22 2019, In : ChemMedChem. 14, 6, p. 615-620 6 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

    Deibler, K. K., Mishra, R. K., Clutter, M. R., Antanasijevic, A., Bergan, R., Caffrey, M. & Scheidt, K. A., May 19 2017, In : ACS chemical biology. 12, 5, p. 1245-1256 12 p.

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Method for identifying small molecule inhibitors of the protein-protein interaction between HCN1 and TRIP8b

    Han, Y., Lyman, K. A., Clutter, M., Schiltz, G. E., Ismail, Q. A., Cheng, X., Luan, C. H. & Chetkovich, D. M., Nov 11 2016, In : Journal of Visualized Experiments. 2016, 117, e54540.

    Research output: Contribution to journal › Article

    • 3 Scopus citations