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Matt Clutter

  • 560 Citations
20052019

Research output per year

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Grants

Development of Novel MNK Inhibitors for Treating Glioblastoma

Clutter, M., Eckerdt, F. D., Horbinski, C. M., James, C. D., Mishra, R. K., Platanias, L. C. & Schiltz, G. E.

National Institute of Neurological Disorders and Stroke

9/1/19 → 6/30/24

Project: Research project

    • Harnessing Druggable Synthetic Lethal Interactions in Triple-Negative Breast Cancer with Elevated MYC Expression

    Clutter, M., Horiuchi, D., Mendillo, M. L., Vasilopoulos, A. & Santa-Maria, C. A.

    U.S. Army Medical Research and Materiel Command

    4/1/18 → 3/31/21

    Project: Research project

    • Discovery of novel small molecule antidepressants

    Clutter, M., Mishra, R. K. & Schiltz, G. E.

    Vanderbilt University, National Institute of Mental Health

    2/1/18 → 1/31/20

    Project: Research project

    • Discovery of novel small molecule antidepressants

    Chetkovich, D. M., Clutter, M., Han, Y., Luan, C., Mishra, R. K. & Schiltz, G. E.

    National Institute of Mental Health

    4/15/16 → 1/31/19

    Project: Research project

    • Subproject for Gary Schiltz for the project titled, "Discovery of novel small molecule antidepressants".

    Clutter, M., Luan, C., Mishra, R. K. & Schiltz, G. E.

    National Institute of Mental Health

    4/15/16 → 1/31/19

    Project: Research project

    • Research Output

    • 560 Citations
    • 13 Article
    • 1 Review article

    Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening

    Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In : Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential (ESP) Charges

    Mishra, R. K., Deibler, K. K., Clutter, M. R., Vagadia, P. P., O'Connor, M., Schiltz, G. E., Bergan, R. & Scheidt, K. A., Jan 1 2019, (Accepted/In press) In : Journal of Chemical Information and Modeling.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

    Deibler, K. K., Schiltz, G. E., Clutter, M., Mishra, R. K., Vagadia, P. P., O'Connor, M., George, M. D., Gordon, R., Fowler, G., Bergan, R. & Scheidt, K. A., Mar 22 2019, In : ChemMedChem. 14, 6, p. 615-620 6 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

    Deibler, K. K., Mishra, R. K., Clutter, M. R., Antanasijevic, A., Bergan, R., Caffrey, M. & Scheidt, K. A., May 19 2017, In : ACS chemical biology. 12, 5, p. 1245-1256 12 p.

    Research output: Contribution to journal › Article

    • 4 Scopus citations

    Method for identifying small molecule inhibitors of the protein-protein interaction between HCN1 and TRIP8b

    Han, Y., Lyman, K. A., Clutter, M., Schiltz, G. E., Ismail, Q. A., Cheng, X., Luan, C. H. & Chetkovich, D. M., Nov 11 2016, In : Journal of Visualized Experiments. 2016, 117, e54540.

    Research output: Contribution to journal › Article

    • 4 Scopus citations