• 520 Citations
20052024
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Fingerprint Dive into the research topics where Matt Clutter is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Flow Cytometry Medicine & Life Sciences
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Medicine & Life Sciences
Phosphotransferases Chemical Compounds
Throughput Chemical Compounds
Cyclic Nucleotides Medicine & Life Sciences
MAP Kinase Kinase 4 Chemical Compounds
Oncology Chemical Compounds
Drug Discovery Medicine & Life Sciences

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Grants 2015 2024

Triple Negative Breast Neoplasms
Neoplasms
Breast Neoplasms
Therapeutics
Mutation
Antidepressive Agents
High-Throughput Screening Assays
Manuscripts
Organized Financing
Research
Cyclic Nucleotides
Antidepressive Agents
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Major Depressive Disorder
Fluorescence Polarization
Cyclic Nucleotides
Antidepressive Agents
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Major Depressive Disorder
Fluorescence Polarization

Research Output 2005 2019

  • 520 Citations
  • 13 Article
  • 1 Review article

Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening

Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In : Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.

Research output: Contribution to journalArticle

Screening
Phosphotransferases
Throughput
Acute Myeloid Leukemia
Mutation

Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential (ESP) Charges

Mishra, R. K., Deibler, K. K., Clutter, M. R., Vagadia, P. P., O'Connor, M., Schiltz, G. E., Bergan, R. & Scheidt, K. A., Jan 1 2019, (Accepted/In press) In : Journal of Chemical Information and Modeling.

Research output: Contribution to journalArticle

Electrostatics
activity structure
Phosphotransferases
non-alignment
predictive model
1 Citation (Scopus)

Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

Deibler, K. K., Schiltz, G. E., Clutter, M., Mishra, R. K., Vagadia, P. P., O'Connor, M., George, M. D., Gordon, R., Fowler, G., Bergan, R. & Scheidt, K. A., Mar 22 2019, In : ChemMedChem. 14, 6, p. 615-620 6 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 4
Benzoic Acid
Molecular modeling
Oncology
p38 Mitogen-Activated Protein Kinases
3 Citations (Scopus)

A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

Deibler, K. K., Mishra, R. K., Clutter, M. R., Antanasijevic, A., Bergan, R., Caffrey, M. & Scheidt, K. A., May 19 2017, In : ACS chemical biology. 12, 5, p. 1245-1256 12 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase Kinases
Mitogen-Activated Protein Kinase Kinases
Phosphotransferases
Oncology
p38 Mitogen-Activated Protein Kinases
3 Citations (Scopus)

Method for identifying small molecule inhibitors of the protein-protein interaction between HCN1 and TRIP8b

Han, Y., Lyman, K. A., Clutter, M., Schiltz, G. E., Ismail, Q. A., Cheng, X., Luan, C. H. & Chetkovich, D. M., Nov 11 2016, In : Journal of Visualized Experiments. 2016, 117, e54540.

Research output: Contribution to journalArticle

Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Cyclic Nucleotides
Proteins
Molecules
Neurons