• 562 Citations
20052019

Research output per year

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Research Output

  • 562 Citations
  • 13 Article
  • 1 Review article
2019

Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening

Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In : Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential (ESP) Charges

Mishra, R. K., Deibler, K. K., Clutter, M. R., Vagadia, P. P., O'Connor, M., Schiltz, G. E., Bergan, R. & Scheidt, K. A., Jan 1 2019, (Accepted/In press) In : Journal of Chemical Information and Modeling.

Research output: Contribution to journalArticle

1 Scopus citations

Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

Deibler, K. K., Schiltz, G. E., Clutter, M., Mishra, R. K., Vagadia, P. P., O'Connor, M., George, M. D., Gordon, R., Fowler, G., Bergan, R. & Scheidt, K. A., Mar 22 2019, In : ChemMedChem. 14, 6, p. 615-620 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

Deibler, K. K., Mishra, R. K., Clutter, M. R., Antanasijevic, A., Bergan, R., Caffrey, M. & Scheidt, K. A., May 19 2017, In : ACS chemical biology. 12, 5, p. 1245-1256 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2016

Method for identifying small molecule inhibitors of the protein-protein interaction between HCN1 and TRIP8b

Han, Y., Lyman, K. A., Clutter, M., Schiltz, G. E., Ismail, Q. A., Cheng, X., Luan, C. H. & Chetkovich, D. M., Nov 11 2016, In : Journal of Visualized Experiments. 2016, 117, e54540.

Research output: Contribution to journalArticle

4 Scopus citations
2015

Identification of small-molecule inhibitors of hyperpolarization-activated cyclic nucleotide-gated channels

Han, Y., Lyman, K., Clutter, M., Schiltz, G. E., Ismail, Q. A., Prados, D. B., Luan, C. H. & Chetkovich, D. M., Oct 22 2015, In : Journal of Biomolecular Screening. 20, 9, p. 1124-1131 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2012

Single-cell mass cytometry adapted to measurements of the cell cycle

Behbehani, G. K., Bendall, S. C., Clutter, M. R., Fantl, W. J. & Nolan, G. P., Jul 2012, In : Cytometry Part A. 81 A, 7, p. 552-566 15 p.

Research output: Contribution to journalArticle

124 Scopus citations
2011

Fluorescent cell barcoding for multiplex flow cytometry

Krutzik, P. O., Clutter, M. R., Trejo, A. & Nolan, G. P., Jan 1 2011, In : Current Protocols in Cytometry. SUPPL.55, 6.31.

Research output: Contribution to journalArticle

55 Scopus citations

Novel hematopoietic progenitor populations revealed by direct assessment of GATA1 protein expression and cMPL signaling events

Heffner, G. C., Clutter, M. R., Nolan, G. P. & Weissman, I. L., Nov 1 2011, In : Stem Cells. 29, 11, p. 1774-1782 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2010

Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry

Clutter, M. R., Heffner, G. C., Krutzik, P. O., Sachen, K. L. & Nolan, G. P., Nov 1 2010, In : Cytometry Part A. 77, 11, p. 1020-1031 12 p.

Research output: Contribution to journalArticle

20 Scopus citations
2008

High-content single-cell drug screening with phosphospecific flow cytometry

Krutzik, P. O., Crane, J. M., Clutter, M. R. & Nolan, G. P., Feb 2008, In : Nature Chemical Biology. 4, 2, p. 132-142 11 p.

Research output: Contribution to journalArticle

151 Scopus citations
2005

Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry

Krutzik, P. O., Clutter, M. R. & Nolan, G. P., Aug 15 2005, In : Journal of Immunology. 175, 4, p. 2357-2365 9 p.

Research output: Contribution to journalArticle

104 Scopus citations

High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3

Chlewicki, L. K., Holler, P. D., Monti, B. C., Clutter, M. R. & Kranz, D. M., Feb 11 2005, In : Journal of Molecular Biology. 346, 1, p. 223-239 17 p.

Research output: Contribution to journalArticle

68 Scopus citations

Phospho-specific flow cytometry in drug discovery

Clutter, M. R., Krutzik, P. O. & Nolan, G. P., Jan 1 2005, In : Drug Discovery Today: Technologies. 2, 3, p. 295-302 8 p.

Research output: Contribution to journalReview article

10 Scopus citations