If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

We examine the neural control of movement, focusing on the role of spinal circuitry.  We use an interdisciplinary approach in this research, using a combination of behavioral, biomechanical, and neurophysiological techniques.  Our current research examines the neural control of internal joint variables, evaluating the hypothesis that the nervous system actively regulates the stresses and strains within joints in order to minimize injury. We examine this issue using biomechanics, characterizing how muscles affect the stresses and strains within joints; using behavioral studies, characterizing how the CNS adapts kinematics and muscle activations to compensate for alterations in joint structures; and using electrophysiological studies, examining the neural systems involved in regulating joint stresses and strains.

We are also developing neuroprostheses for restoring functional movements following spinal cord injury. This is collaborative work with Dr. Lee Miller.  Previous work from his lab has shown the potential of cortically controlled FES: using cortical predictions of muscle activation to drive stimulation of paralyzed muscles, thereby restoring natural control of a paralyzed animals’ own limb.  We are developing these procedures in a rodent model, examining whether this approach can be used to restore the hindlimb movements underlying locomotion in animals paralyzed by spinal cord injury.

Education/Academic qualification

Neuroscience, PhD, Massachusetts Institute of Technology

… → 1998

Psychology, BA, Wesleyan University

… → 1992

Research interests

  • Coordination
  • Motor control
  • Muscle synergies
  • Nervous system
  • Neuro-physiological substrates of motor coordination
  • Restoration after injury
  • Spinal cord
  • Synchronization in spinal cord function


Dive into the research topics where Matthew C Tresch is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles


Recent external collaboration on country/territory level. Dive into details by clicking on the dots or