Grants per year
Personal profile
Research Interests
Matthew Feinstein, MD MSc is a cardiologist at Northwestern Medicine and an assistant professor at the Northwestern University Feinberg School of Medicine with a dual appointment in the Department of Medicine and Department of Preventive Medicine Dr. Feinstein is a physician-scientist with expertise in immune and inflammatory triggers of cardiovascular diseases. Much of Dr. Feinstein's work has analyzed human immunodeficiency virus (HIV) as a model of chronic immune dysregulation leading to cardiovascular disease. Dr. Feinstein is an elected Fellow of the American Heart Association (AHA), served as writing chair of the AHA Scientific Statement on HIV and cardiovascular disease (https://www.ahajournals.org/doi/abs/10.1161/CIR.0000000000000695?af=R), and is actively involved as an elected investigator and faculty contributor on several AHA committees. He also serves as an investigator for the AIDS Clinical Trials Group End-Organ Disease and Inflammation Transformative Science Group as well as the Pediatric HIV/AIDS Cohort Study Metabolic Working Group. Dr. Feinstein was awarded an American Society of Clincial Investigation (ASCI) Young Investigator Award, and was voted a finalist for the AHA Stamler Award for New Investigators and the ACC Young Investigator Award Competition. He was a recipient of the prestigious AHA Fellow-to-Faculty Transition Award and has also received grant funding for his work from the National Institutes of Health. He and his work have been featured nationally on ABC World News Tonight, CBS, Time Magazine, Fox News, the Chicago Tribune, and NPR, as well as internationally on Voice of America, the Economic Times, African Medical Digest, and the Gulf Times. Dr. Feinstein received his bachelor of arts in sociology from Princeton University. He received his MD and MS in clinical investigation from Northwestern University Feinberg School of Medicine. He completed his internship and residency in internal medicine at Northwestern University and completed his fellowship in cardiovascular medicine at Northwestern University.
Certifications and Licenses
Internal Medicine | |
Cardiology |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Northwestern University
… → 2011
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Collaborations and top research areas from the last five years
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Element B + Subcontracts
Becker, S. (PD/PI), D'Aquila, R. T. (PD/PI), Yancy, C. W. (PD/PI), Alshurafa, N. (Other), Ameer, G. A. (Other), Beidas, R. S. (Other), Blanco, I. (Other), Bradley, C. D. (Other), Brawley, C. (Other), Brown, O. E. (Other), Brown, C. H. (Other), Cameron, K. A. (Other), Carnethon, M. R. (Other), Cooper, L. A. D. (Other), Feinstein, M. J. (Other), Franklin, P. D. (Other), Helseth, S. A. (Other), Hill, V. B. (Other), Holmes, K. (Other), Kalhan, R. (Other), Khan, S. S. (Other), Kho, A. N. (Other), Li, D. H. (Other), Liebovitz, D. M. (Other), Luo, Y. (Other), Macapagal, K. (Other), O'Brien, M. J. (Other), Passman, R. S. (Other), Perreault, E. (Other), Peters, A. T. (Other), Pickens, C. I. (Other), Rasmussen-Torvik, L. J. (Other), Rivnay, J. (Other), Rosenberg, S. R. (Other), Schauer, J. M. (Other), Scott, K. (Other), Scott, E. A. (Other), Simon, M. A. (Other), Skolarus, L. E. (Other), Spring, B. (Other), Starren, J. (Other), Tandon, D. (Other), Walunas, T. L. (Other), Welty, L. J. (Other), Woitowich, N. C. (Other) & Wolf, M. (Other)
National Center for Advancing Translational Sciences
9/1/24 → 7/31/31
Project: Research project
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Integrated epidemiology of systemic and plaque-specific immunologic features of human atherosclerosis
Feinstein, M. J. (PD/PI), Thorp, E. B. (PD/PI), Alexandria, S. J. (Co-Investigator), Lloyd-Jones, D. M. (Co-Investigator), Lomasney, J. W. (Co-Investigator), Rasmussen-Torvik, L. J. (Co-Investigator) & Glinton, K. E. (Other)
National Heart, Lung, and Blood Institute
8/1/24 → 5/31/28
Project: Research project
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Dynamic Inflammatory Determinants of Heart Failure with Preserved Ejection Fraction
Feinstein, M. J. (PD/PI), Carnethon, M. R. (Co-Investigator), Fourati, S. (Co-Investigator), Lloyd-Jones, D. M. (Co-Investigator) & Walunas, T. L. (Co-Investigator)
4/1/24 → 3/31/28
Project: Research project
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Clinical Project II Monocyte inflammatory priming in human HFpEF
Feinstein, M. J. (PD/PI), Shah, S. J. (Co-PD/PI) & Fourati, S. (Co-Investigator)
4/1/24 → 3/31/28
Project: Research project
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Role of dynamic stressors in inflammation and early HFpEF risk
Feinstein, M. J. (PD/PI), Kershaw, K. N. (PD/PI), Kershaw, K. N. (Co-PD/PI), Alexandria, S. J. (Co-Investigator), Khan, S. S. (Co-Investigator) & Patel, R. B. (Co-Investigator)
4/1/24 → 3/31/28
Project: Research project
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CCR2+ monocytes promote white matter injury and cognitive dysfunction after myocardial infarction
Thorp, E. B., Filipp, M., Dima, M., Tan, C., Feinstein, M., Popko, B. & DeBerge, M. P., Jul 2024, In: Brain, Behavior, and Immunity. 119, p. 818-835 18 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Designing target trials using electronic health records: A case study of second-line disease-modifying anti-rheumatic drugs and cardiovascular disease outcomes in patients with rheumatoid arthritis
Rivera, A. S., Pierce, J. B., Sinha, A., Pawlowski, A. E., Lloyd-Jones, D. M., Lee, Y. C., Feinstein, M. J. & Petito, L. C., Jun 2024, In: PloS one. 19, 6 June, e0305467.Research output: Contribution to journal › Article › peer-review
Open Access -
Evolving mechanisms and presentations of cardiovascular disease in people with HIV: implications for management
Nazari, I. & Feinstein, M. J., Mar 2024, In: Clinical microbiology reviews. 37, 1, e00098-22.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Human immunology of heart failure: deconstructing inflammatory risk
Feinstein, M. J., Jul 21 2024, In: European heart journal. 45, 28, p. 2505-2507 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access1 Scopus citations -
Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant
Gao, J., Giro, P., Delaney, J. A., Rasmussen-Torvik, L., Taylor, K. D., Thorp, E. B., Doyle, M. F., Feinstein, M. J., Sitlani, C. M., Olson, N., Tracy, R., Shah, S. J., Psaty, B. M. & Patel, R. B., 2024, (Accepted/In press) In: ESC Heart Failure.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Mortality following myocardial infarction among HIV-infected persons: the Center for AIDS Research Network Of Integrated Clinical Systems (CNICS)
Feinstein, M. J. (Creator), Nance, R. M. (Creator), Delaney, J. A. C. (Contributor), Heckbert, S. R. (Creator), Budoff, M. J. (Creator), Drozd, D. R. (Creator), Burkholder, G. A. (Creator), Willig, J. H. (Creator), Mugavero, M. J. (Creator), Mathews, W. C. (Creator), Moore, R. D. (Creator), Eron, J. J. (Creator), Napravnik, S. (Creator), Hunt, P. W. (Creator), Geng, E. (Creator), Hsue, P. (Creator), Peter, I. (Creator), Lober, W. B. (Creator), Crothers, K. (Creator), Grunfeld, C. (Creator), Saag, M. S. (Creator), Kitahata, M. M. (Creator), Lloyd-Jones, D. M. (Creator) & Crane, H. M. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4601540, https://springernature.figshare.com/collections/Mortality_following_myocardial_infarction_among_HIV-infected_persons_the_Center_for_AIDS_Research_Network_Of_Integrated_Clinical_Systems_CNICS_/4601540
Dataset
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Natural killer cells, gamma delta T cells and classical monocytes are associated with systolic blood pressure in the multi-ethnic study of atherosclerosis (MESA)
Delaney, J. A. C. (Creator), Olson, N. C. (Creator), Sitlani, C. M. (Creator), Fohner, A. E. (Creator), Huber, S. A. (Creator), Landay, A. L. (Creator), Heckbert, S. R. (Creator), Tracy, R. P. (Creator), Psaty, B. M. (Creator), Feinstein, M. (Creator) & Doyle, M. F. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5279213, https://springernature.figshare.com/collections/Natural_killer_cells_gamma_delta_T_cells_and_classical_monocytes_are_associated_with_systolic_blood_pressure_in_the_multi-ethnic_study_of_atherosclerosis_MESA_/5279213
Dataset