Matthias Dominikus Hofer

  • 3968 Citations
20032020

Research output per year

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Research Output

2003

The Role of an 80 kDa Fragment of E-cadherin in the Metastatic Progression of Prostate Cancer

Kuefer, R., Hofer, M. D., Gschwend, J. E., Pienta, K. J., Sanda, M. G., Chinnaiyan, A. M., Rubin, M. A. & Day, M. L., Dec 15 2003, In : Clinical Cancer Research. 9, 17, p. 6447-6452 6 p.

Research output: Contribution to journalArticle

69 Scopus citations
2004

Expression of MTAI promotes motility and invasiveness of PANC-I pancreatic carcinoma cells

Hofer, M. D., Menke, A., Genze, F., Gierschik, P. & Giehl, K., Jan 26 2004, In : British Journal of Cancer. 90, 2, p. 455-462 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors

Hofer, M. D., Fecko, A., Shen, R., Setlur, S. R., Pienta, K. G., Tomlins, S. A., Chinnaiyan, A. M. & Rubin, M. A., Jan 1 2004, In : Neoplasia. 6, 5, p. 503-512 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

Santagata, S., Demichelis, F., Riva, A., Varambally, S., Hofer, M. D., Kutok, J. L., Kim, R., Tang, J., Montie, J. E., Chinnaiyan, A. M., Rubin, M. A. & Aster, J. C., Oct 1 2004, In : Cancer Research. 64, 19, p. 6854-6857 4 p.

Research output: Contribution to journalArticle

272 Scopus citations

Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

Rubin, M. A., Varambally, S., Beroukhim, R., Tomlins, S. A., Rhodes, D. R., Paris, P. L., Hofer, M. D., Storz-Schweizer, M., Kuefer, R., Fletcher, J. A., Hsi, B. L., Byrne, J. A., Pienta, K. J., Collins, C., Sellers, W. R. & Chinnaiyan, A. M., Jun 1 2004, In : Cancer Research. 64, 11, p. 3814-3822 9 p.

Research output: Contribution to journalArticle

124 Scopus citations

Quantitative Determination of Expression of the Prostate Cancer Protein α-Methylacyl-CoA Racemase Using Automated Quantitative Analysis (AQUA): A Novel Paradigm for Automated and Continuous Biomarker Measurements

Rubin, M. A., Zerkowski, M. P., Camp, R. L., Kuefer, R., Hofer, M. D., Chinnaiyan, A. M. & Rimm, D. L., Mar 2004, In : American Journal of Pathology. 164, 3, p. 831-840 10 p.

Research output: Contribution to journalArticle

127 Scopus citations

Sodium butyrate and tributyrin induce in vivo growth inhibition and apoptosis in human prostate cancer

Kuefer, R., Hofer, M. D., Altug, V., Zorn, C., Genze, F., Kunzi-Rapp, K., Hautmann, R. E. & Gschwend, J. E., Jan 26 2004, In : British Journal of Cancer. 90, 2, p. 535-541 7 p.

Research output: Contribution to journalArticle

118 Scopus citations

The Role of Metastasis-Associated Protein 1 in Prostate Cancer Progression

Hofer, M. D., Kuefer, R., Varambally, S., Li, H., Ma, J., Shapiro, G. I., Gschwend, J. E., Hautmann, R. E., Sanda, M. G., Giehl, K., Menke, A., Chinnaiyan, A. M. & Rubin, M. A., Feb 1 2004, In : Cancer Research. 64, 3, p. 825-829 5 p.

Research output: Contribution to journalArticle

116 Scopus citations

Tissue-microarrays. Ein hochdurchsatzverfahren zur verifizierung potenzieller biomarker

Translated title of the contribution: Tissue microarrays. High-throughput procedures to verify potential biomarkersKuefer, R., Hofer, M. D., Gschwend, J. E. & Rubin, M. A., Jun 1 2004, In : Urologe - Ausgabe A. 43, 6, p. 659-667 9 p.

Research output: Contribution to journalReview article

14 Scopus citations
2005

Amplification and overexpression of prosaposin in prostate cancer

Koochekpour, S., Zhang, Y., Beroukhim, R., Hsieh, C. L., Hofer, M. D., Zhau, H. E., Hiraiwa, M., Pattan, D. Y., Ware, J. L., Luftig, R. B., Sandhoff, K., Sawyers, C. L., Pienta, K. J., Rubin, M. A., Vessella, R. L., Sellers, W. R. & Sartor, O., Dec 2005, In : Genes Chromosomes and Cancer. 44, 4, p. 351-364 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Assessment of a fragment of e-cadherin as a serum biomarker with predictive value for prostate cancer

Kuefer, R., Hofer, M. D., Zorn, C. S. M., Engel, O., Volkmer, B. G., Juarez-Brito, M. A., Eggel, M., Gschwend, J. E., Rubin, M. A. & Day, M. L., Jun 6 2005, In : British Journal of Cancer. 92, 11, p. 2018-2023 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Evolution of health-related quality of life two to seven years after retropubic radical prostatectomy: evaluation by UCLA prostate cancer index.

Descazeaud, A., Zerbib, M., Hofer, M. D., Chaskalovic, J., Debré, B. & Peyromaure, M., Sep 2005, In : World journal of urology. 23, 4, p. 257-262 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Identification of two molecular groups of seminomas by using expression and tissue microarrays

Hofer, M. D., Browne, T. J., He, L., Skotheim, R. I., Lothe, R. A. & Rubin, M. A., Aug 15 2005, In : Clinical Cancer Research. 11, 16, p. 5722-5729 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2006

ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease

Kuefer, R., Day, K. C., Kleer, C. G., Sabel, M. S., Hofer, M. D., Varambally, S., Zorn, C. S., Chinnaiyan, A. M., Rubin, M. A. & Day, M. L., Jan 1 2006, In : Neoplasia. 8, 4, p. 319-329 11 p.

Research output: Contribution to journalArticle

71 Scopus citations

Characterization of ZAG protein expression in prostate cancer using a semi-automated microscope system

Descazeaud, A., De La Taille, A., Allory, Y., Faucon, H., Salomon, L., Bismar, T., Kim, R., Hofer, M. D., Chopin, D., Abbou, C. C. & Rubin, M. A., Jul 1 2006, In : Prostate. 66, 10, p. 1037-1043 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Comprehensive analysis of the expression of the metastasis-associated gene 1 in human neoplastic tissue

Hofer, M. D., Tapia, C., Browne, T. J., Mirlacher, M., Sauter, G. & Rubin, M. A., Jul 1 2006, In : Archives of Pathology and Laboratory Medicine. 130, 7, p. 989-996 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Defining aggressive prostate cancer using a 12-gene model

Bismar, T. A., Demichelis, F., Riva, A., Kim, R., Varambally, S., He, L., Kutok, J., Aster, J. C., Tang, J., Kuefer, R., Hofer, M. D., Febbo, P. G., Chinnaiyan, A. M. & Rubin, M. A., Jan 2006, In : Neoplasia. 8, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer

Davis, J. N., Wojno, K. J., Daignault, S., Hofer, M. D., Kuefer, R., Rubin, M. A. & Day, M. L., Dec 15 2006, In : Cancer Research. 66, 24, p. 11897-11906 10 p.

Research output: Contribution to journalArticle

76 Scopus citations

Genomic profiling of hormone-naïve lymph node metastases in patients with prostate cancer

Paris, P. L., Hofer, M. D., Albo, G., Kuefer, R., Gschwend, J. E., Hautmann, R. E., Fridyland, J., Simko, J., Carroll, P. R., Rubin, M. A. & Collins, C., Dec 2006, In : Neoplasia. 8, 12, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays

Beroukhim, R., Lin, M., Park, Y., Hao, K., Zhao, X., Garraway, L. A., Fox, E. A., Hochberg, E. P., Mellinghoff, I. K., Hofer, M. D., Descazeaud, A., Rubin, M. A., Meyerson, M., Wing, H. W., Sellers, W. R. & Li, C., May 2006, In : PLoS computational biology. 2, 5, p. 323-332 10 p.

Research output: Contribution to journalArticle

123 Scopus citations

Prognostic factors in lymph node-positive prostate cancer

Hofer, M. D., Kuefer, R., Huang, W., Li, H., Bismar, T. A., Perner, S., Hautmann, R. E., Sanda, M. G., Gschwend, J. E. & Rubin, M. A., May 1 2006, In : Urology. 67, 5, p. 1016-1021 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

Perner, S., Demichelis, F., Beroukhim, R., Schmidt, F. H., Mosquera, J. M., Setlur, S., Tchinda, J., Tomlins, S. A., Hofer, M. D., Pienta, K. G., Kuefer, R., Vessella, R., Sun, X. W., Meyerson, M., Lee, C., Sellers, W. R., Chinnaiyan, A. M. & Rubin, M. A., Sep 1 2006, In : Cancer Research. 66, 17, p. 8337-8341 5 p.

Research output: Contribution to journalArticle

406 Scopus citations

Translation molekularer zusammenhänge in die klinische anwendung. Dargestellt am beispiel des vascular-endothelial-growth-factor-(VEGF-)pathway

Translated title of the contribution: Translational research in renal cell cancer. Illustrated by the example of the vascular endothelial growth factor pathwayKuefer, R., Autenrieth, M., Herkommer, K., Blum, P., Merseburger, A., Hofer, M., Rinnab, L., Gschwend, J. & Ringhoffer, M., Mar 1 2006, In : Urologe - Ausgabe A. 45, 3, p. 328-335 8 p.

Research output: Contribution to journalReview article

1 Scopus citations
2007

Collagen XXIII expression is associated with prostate cancer recurrence and distant metastases

Banyard, J., Bao, L., Hofer, M. D., Zurakowski, D., Spivey, K. A., Feldman, A. S., Hutchinson, L. M., Kuefer, R., Rubin, M. A. & Zetter, B. R., May 1 2007, In : Clinical Cancer Research. 13, 9, p. 2634-2642 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Die TMPRSS2-ETS-genfusion beim prostatakarzinom

Translated title of the contribution: TMPRSS2-ETS gene fusion in prostate cancerPerner, S., Schmidt, F. H., Hofer, M. D., Kuefer, R. & Rubin, M., Jul 1 2007, In : Urologe - Ausgabe A. 46, 7, p. 754-760 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Erratum: Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays (PLoS Computational Biology 2, 5, doi:10.1371/journal.pcbi.0020041)

Beroukhim, R., Lin, M., Park, Y., Hao, K., Zhao, X., Garraway, L. A., Fox, E. A., Hochberg, E. P., Mellinghoff, I. K., Hofer, M. D., Descazeaud, A., Rubin, M. A., Meyerson, M., Wing, H. W., Sellers, W. R. & Li, C., Feb 1 2007, In : PLoS computational biology. 3, 2, 1 p.

Research output: Contribution to journalComment/debate

Integrative microarray analysis of pathways dysregulated in metastatic prostate cancer

Setlur, S. R., Royce, T. E., Sboner, A., Mosquera, J. M., Demichelis, F., Hofer, M. D., Mertz, K. D., Gerstein, M. & Rubin, M. A., Nov 1 2007, In : Cancer Research. 67, 21, p. 10296-10303 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Morphological features of TMPRSS2-ERG gene fusion prostate cancer

Mosquera, J. M., Perner, S., Demichelis, F., Kim, R., Hofer, M. D., Mertz, K. D., Paris, P. L., Simko, J., Collins, C., Bismar, T. A., Chinnaiyan, A. M. & Rubin, M. A., May 2007, In : Journal of Pathology. 212, 1, p. 91-101 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Prostate-specific membrane antigen expression as a predictor of prostate cancer progression

Perner, S., Hofer, M. D., Kim, R., Shah, R. B., Li, H., Möller, P., Hautmann, R. E., Gschwend, J. E., Kuefer, R. & Rubin, M. A., May 1 2007, In : Human pathology. 38, 5, p. 696-701 6 p.

Research output: Contribution to journalArticle

257 Scopus citations

TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion

Perner, S., Mosquera, J. M., Demichelis, F., Hofer, M. D., Paris, P. L., Simko, J., Collins, C., Bismar, T. A., Chinnaiyan, A. M., De Marzo, A. M. & Rubin, M. A., Jun 2007, In : American Journal of Surgical Pathology. 31, 6, p. 882-888 7 p.

Research output: Contribution to journalArticle

327 Scopus citations
2008

BPH gene expression profile associated to prostate gland volume

Descazeaud, A., Rubin, M. A., Hofer, M., Setlur, S., Nikolaief, N., Vacherot, F., Soyeux, P., Kheuang, L., Abbou, C. C., Allory, Y. & De La Taille, A., Dec 2008, In : Diagnostic Molecular Pathology. 17, 4, p. 207-213 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications

Mosquera, J. M., Perner, S., Genega, E. M., Sanda, M., Hofer, M. D., Mertz, K. D., Paris, P. L., Simko, J., Bismar, T. A., Ayala, G., Shah, R. B., Loda, M. & Rubin, M. A., Jun 1 2008, In : Clinical Cancer Research. 14, 11, p. 3380-3385 6 p.

Research output: Contribution to journalArticle

165 Scopus citations
2009

Distinct genomic aberrations associated with ERG rearranged prostate cancer

Demichelis, F., Setlur, S. R., Beroukhim, R., Perner, S., Korbel, J. O., Lafargue, C. J., Pflueger, D., Pina, C., Hofer, M. D., Sboner, A., Svensson, M. A., Rickman, D. S., Urban, A., Snyder, M., Meyerson, M., Lee, C., Gerstein, M. B., Kuefer, R. & Rubin, M. A., Apr 2009, In : Genes Chromosomes and Cancer. 48, 4, p. 366-380 15 p.

Research output: Contribution to journalArticle

78 Scopus citations

Genome-wide linkage analysis of TMPRSS2-ERG fusion in familial prostate cancer

Hofer, M. D., Kuefer, R., Maier, C., Herkommer, K., Perner, S., Demichelis, F., Paiss, T., Vogel, W., Rubin, M. A. & Hoegel, J., Jan 15 2009, In : Cancer Research. 69, 2, p. 640-646 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Immunohistochemical and clinicopathological correlation of the metastasis-associated gene 1 (MTA1) expression in benign and malignant pancreatic endocrine tumors

Hofer, M. D., Chang, M. C., Hirko, K. A., Rubin, M. A. & Nosé, V., Jul 1 2009, In : Modern Pathology. 22, 7, p. 933-939 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Predisposition for TMPRSS2-ERG fusion in prostate cancer by variants in DNA repair genes

Luedeke, M., Linnert, C. M., Hofer, M. D., Surowy, H. M., Rinckleb, A. E., Hoegel, J., Kuefer, R., Rubin, M. A., Vogel, W. & Maier, C., Nov 1 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 11, p. 3030-3035 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease

Gust, K. M., Hofer, M. D., Perner, S. R., Kim, R., Chinnaiyan, A. M., Varambally, S., Moller, P., Rinnab, L., Rubin, M. A., Greiner, J., Schmitt, M., Kuefer, R. & Ringhoffer, M., Sep 2009, In : Neoplasia. 11, 9, p. 956-963 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

Steinkamp, M. P., O'Mahony, O. A., Brogley, M., Rehman, H., LaPensee, E. W., Dhanasekaran, S., Hofer, M. D., Kuefer, R., Chinnaiyan, A., Rubin, M. A., Pienta, K. J. & Robins, D. M., May 15 2009, In : Cancer Research. 69, 10, p. 4434-4442 9 p.

Research output: Contribution to journalArticle

147 Scopus citations
2010

ERG Rearrangement Metastasis Patterns in Locally Advanced Prostate Cancer

Perner, S., Svensson, M. A., Hossain, R. R., Day, J. R., Groskopf, J., Slaughter, R. C., Jarleborn, A. R., Hofer, M. D., Kuefer, R., Demichelis, F., Rickman, D. S. & Rubin, M. A., Apr 2010, In : Urology. 75, 4, p. 762-767 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Skin inflammation arising from cutaneous regulatory T cell deficiency leads to impaired viral immune responses

Freyschmidt, E. J., Mathias, C. B., Diaz, N., MacArthur, D. H., Laouar, A., Manjunath, N., Hofer, M. D., Wurbel, M. A., Campbell, J. J., Chatila, T. A. & Oettgen, H. C., Jul 15 2010, In : Journal of Immunology. 185, 2, p. 1295-1302 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2011

Delay of surgery in men with low risk prostate cancer

O'Brien, D., Loeb, S., Carvalhal, G. F., McGuire, B. B., Kan, D., Hofer, M. D., Casey, J. T., Helfand, B. T. & Catalona, W. J., Jun 1 2011, In : Journal of Urology. 185, 6, p. 2143-2147 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

Differentiation of NUT midline carcinoma by epigenomic reprogramming

Schwartz, B. E., Hofer, M. D., Lemieux, M. E., Bauer, D. E., Cameron, M. J., West, N. H., Agoston, E. S., Reynoird, N., Khochbin, S., Ince, T. A., Christie, A., Janeway, K. A., Vargas, S. O., Perez-Atayde, A. R., Aster, J. C., Sallan, S. E., Kung, A. L., Bradner, J. E. & French, C. A., Apr 1 2011, In : Cancer Research. 71, 7, p. 2686-2696 11 p.

Research output: Contribution to journalArticle

111 Scopus citations
2012

Spiral array, A new high-throughput technology covers tissue heterogeneity

Fukuoka, J., Hofer, M. D., Hori, T., Tanaka, T., Ishizawa, S., Nomoto, K., Saito, M., Uemura, T. & Chirieac, L. R., Nov 2012, In : Archives of Pathology and Laboratory Medicine. 136, 11, p. 1377-1384 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013
30 Scopus citations

Protein markers of malignant potential in penile and vulvar lichen sclerosus

Carlson, B. C., Hofer, M. D., Ballek, N., Yang, X. J., Meeks, J. J. & Gonzalez, C. M., Aug 1 2013, In : Journal of Urology. 190, 2, p. 399-406 8 p.

Research output: Contribution to journalReview article

22 Scopus citations
2014

Analysis of primary urethral wound healing in the rat

Hofer, M. D., Cheng, E. Y., Bury, M. I., Park, E., Xu, W., Hong, S. J., Kaplan, W. E. & Sharma, A. K., Jan 1 2014, In : Urology. 84, 1, p. 246.e1-246.e7

Research output: Contribution to journalArticle

17 Scopus citations

Full-thickness skin grafts for hypospadias repair

Hofer, M. D., Han, J. S. & Gonzalez, C. M., Jul 1 2014, Hypospadias Surgery: Challenges and Limits. Nova Science Publishers, Inc., p. 101-117 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lichen sclerosus and isolated bulbar urethral stricture disease

Liu, J. S., Walker, K., Stein, D., Prabhu, S., Hofer, M. D., Han, J., Yang, X. J. & Gonzalez, C. M., Sep 2014, In : Journal of Urology. 192, 3, p. 775-779 5 p.

Research output: Contribution to journalArticle

21 Scopus citations