Grants per year
Personal profile
Research Interests
Understanding prostate cancer using molecular biology approaches in combination with transgenic mouse model has been the main focus of my independent and collaborative research. I have an extensive expertise in mouse models as well as molecular characteristics of cancer cells. My ultimate research goal is to translate what we have learned in the laboratory setting into clinically relevant therapy, which is evidenced by my grant supports oriented to translational research. Recently, I have been working with Dr. Schaeffer to understand the molecular alterations behind the racial disparity of African American men in prostate cancer, specifically the role of VGLL3, a newly identified novel racial disparity modulator in prostate cancer. Our focus is to investigate its role and underlying molecular mechanism as well as its value as a biomarker in prostate cancer using various cancer cell models. I am well-qualified to perform this proposal based on extensive molecular biology and translational research experience and collaboration expertise.
Education/Academic qualification
PhD, University of Alabama at Birmingham
… → 2001
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Grants
Molecular and clinical investigations to reduce the morbidity of prostate cancer
Abdulkadir, S. A., Roh, M. & Schaeffer, E. M.
Prostate Cancer Foundation, Canica AS
12/1/16 → 12/21/19
Project: Research project
Two-step Approach for Advanced Prostate Cancer Management: Targeting PLK1 After Castration
U.S. Army Medical Research and Materiel Command
6/1/15 → 11/30/16
Project: Research project
Research Output
Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids
Unno, K., Roh, M., Yoo, Y. A., Al-Shraideh, Y., Wang, L., Nonn, L. & Abdulkadir, S. A., Feb 7 2017, In : Oncotarget. 8, 31, p. 51264-51276 13 p.Research output: Contribution to journal › Article
8
Scopus
citations
Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation
Yoo, Y. A., Roh, M., Naseem, A. F., Lysy, B., Desouki, M. M., Unno, K. & Abdulkadir, S. A., Oct 5 2016, In : Nature communications. 7, 12943.Research output: Contribution to journal › Article
27
Scopus
citations
SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth
Park, S. H., Ozden, O., Liu, G., Song, H. Y., Zhu, Y., Yan, Y., Zou, X., Kang, H. J., Jiang, H., Principe, D. R., Cha, Y. I., Roh, M., Vassilopoulos, A. & Gius, D., Jul 1 2016, In : Cancer Research. 76, 13, p. 3802-3812 11 p.Research output: Contribution to journal › Article
36
Scopus
citations
RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibition
Van Der Meer, R., Song, H. Y., Park, S. H., Abdulkadir, S. A. & Roh, M., Jun 15 2014, In : Clinical Cancer Research. 20, 12, p. 3211-3221 11 p.Research output: Contribution to journal › Article
16
Scopus
citations
A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53
Kim, J., Roh, M., Doubinskaia, I., Algarroba, G. N., Eltoum, I. E. A. & Abdulkadir, S. A., Jan 19 2012, In : Oncogene. 31, 3, p. 322-332 11 p.Research output: Contribution to journal › Article
34
Scopus
citations