Grants per year
Personal profile
Education/Academic qualification
PhD, Ohio State University
… → 1990
Fingerprint Dive into the research topics where Mesut Eren is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Plasminogen Activator Inhibitor 1
Medicine & Life Sciences
Transgenic Mice
Medicine & Life Sciences
Transforming Growth Factors
Medicine & Life Sciences
Flavodoxin
Medicine & Life Sciences
Cell Aging
Medicine & Life Sciences
Plasminogen Inactivators
Medicine & Life Sciences
Synthetic Genes
Medicine & Life Sciences
NG-Nitroarginine Methyl Ester
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2008 2022
PAI-1 and Vascular Senescence
Abdelwahid, E., Eren, M., Ghosh, A. K., Khan, S. S., Shah, S. J., Vaughan, D. E. & Flevaris, P. D.
National Heart, Lung, and Blood Institute
8/1/18 → 7/31/22
Project: Research project
Plasminogen Activator Inhibitor 1
Blood Vessels
Cardiovascular System
Population
Personal Financing
PAI-1 and Vascular Senescence
Eren, M., Hayes, M. G., Mackie, A. R., Shah, S. J. & Vaughan, D. E.
National Heart, Lung, and Blood Institute
7/1/14 → 5/31/18
Project: Research project
Plasminogen Activator Inhibitor 1
Blood Vessels
Cardiovascular System
Population
Personal Financing
Project 2 - Vaughan
Eren, M., Ghosh, A. K. & Vaughan, D. E.
National Heart, Lung, and Blood Institute
9/7/11 → 4/30/16
Project: Research project
Stem Cells
Cell- and Tissue-Based Therapy
Therapeutics
Ischemia
Extremities
Cardiovascular Regenerative Medicine
Ardehali, H., Eren, M., Ghosh, A. K., Kume, T., Macrenaris, K. W., Meade, T. J., Perlman, H. R., Schumacker, P. T., Stupp, S., Vaughan, D. E., Vaughan, D. E. & Wasserstrom, J. A.
National Heart, Lung, and Blood Institute
9/7/11 → 4/30/16
Project: Research project
Regenerative Medicine
Stem Cells
Cell- and Tissue-Based Therapy
Therapeutics
Ischemia
Angiotensin, The Vascular Endothelium, and Fibrinolysis
Eren, M., Ghosh, A. K. & Vaughan, D. E.
National Heart, Lung, and Blood Institute
10/1/08 → 3/31/12
Project: Research project
Research Output 1989 2019
Acetyltransferase p300 inhibitor reverses hypertension-induced cardiac fibrosis
Rai, R., Sun, T., Ramirez, V., Lux, E., Eren, M., Vaughan, D. E. & Ghosh, A. K., Apr 1 2019, In : Journal of Cellular and Molecular Medicine. 23, 4, p. 3026-3031 6 p.Research output: Contribution to journal › Article
Open Access
Cardiomegaly
Fibrosis
Hypertension
Epigenomics
Myofibroblasts
14
Citations
(Scopus)
A null mutation in SERPINE1 protects against biological aging in humans
Khan, S. S., Shah, S. J., Klyachko, E., Baldridge, A. S., Eren, M., Place, A. T., Aviv, A., Puterman, E., Lloyd-Jones, D. M., Heiman, M., Miyata, T., Gupta, S., Shapiro, A. D. & Vaughan, D. E., Jan 1 2017, In : Science Advances. 3, 11, eaao1617.Research output: Contribution to journal › Article
Plasminogen Activators
Amish
Mutation
Cell Aging
Telomere
9
Citations
(Scopus)
Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan
Rai, R., Ghosh, A. K., Eren, M., Mackie, A. R., Levine, D. C., Kim, S. Y., Cedernaes, J., Ramirez, V., Procissi, D., Smith, L. H., Woodruff, T. K., Bass, J. & Vaughan, D. E., Nov 7 2017, In : Cell Reports. 21, 6, p. 1471-1480 10 p.Research output: Contribution to journal › Article
Restoration
Down-Regulation
Aging of materials
Cell Aging
Cardiomegaly
10
Citations
(Scopus)
Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis
Kim, S. J., Cheresh, P., Eren, M., Jablonski, R. P., Yeldandi, A., Ridge, K. M., Scott Budinger, G. R., Kim, D. H., Wolf, M., Vaughan, D. E. & Kamp, D. W., Jan 1 2017, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 1, p. L16-L26Research output: Contribution to journal › Article
Alveolar Epithelial Cells
Mitochondrial DNA
Oxidants
DNA Damage
Apoptosis
6
Citations
(Scopus)
PAI-1 is a critical regulator of FGF23 homeostasis
Eren, M., Place, A. T., Thomas, P. M., Flevaris, P., Miyata, T. & Vaughan, D. E., Jan 1 2017, In : Science Advances. 3, 9, 1603259.Research output: Contribution to journal › Article
Plasminogen Activators
Homeostasis
fibroblast growth factor 23
Proteolysis
Urokinase-Type Plasminogen Activator