Michael J Avram

  • 4377 Citations
1976 …2023
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Personal profile

Research Interests

Dr. Avram’s research interests include pharmacokinetics (PKs) and pharmacodynamics (PDs) of hypnotics, sedatives, opioids, analgesics, non-depolarizing neuromuscular blockers, chemotherapeutics, etc. His major research focus has been the development and evaluation of detailed PK models of rapidly acting intravanously administered drugs from the moment of injection to serve as the basis for understanding the PK basis of interindividual variability in response to these agents, which often have low clinical margins of safety.

Education/Academic qualification

PhD, Loyola University Chicago

… → 1980

Research interests

  • Aging
  • Anesthesiology
  • Clinical Pharmacology
  • Oncology
  • Pain Management
  • Pharmacokinetics
  • Pharmacology
  • Physiology

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Grants 2006 2023

Mass spectrometers
High pressure liquid chromatography

Research Output 1976 2020

Microbiota composition modulates inflammation and neointimal hyperplasia after arterial angioplasty

Cason, C. A., Kuntz, T. M., Chen, E. B., Wun, K., Nooromid, M. J., Xiong, L., Gottel, N. R., Harris, K. G., Morton, T. C., Avram, M. J., Chang, E. B., Gilbert, J. A. & Ho, K. J., Jan 1 2020, (Accepted/In press) In : Journal of Vascular Surgery.

Research output: Contribution to journalArticle

Balloon Angioplasty

Postoperative Pain and Analgesic Requirements in the First Year after Intraoperative Methadone for Complex Spine and Cardiac Surgery

Murphy, G. S., Avram, M. J., Greenberg, S. B., Shear, T. D., Deshur, M. A., Dickerson, D., Bilimoria, S., Benson, J., Maher, C. E., Trenk, G. J., Teister, K. J. & Szokol, J. W., Feb 1 2020, In : Anesthesiology. 132, 2, p. 330-342 13 p.

Research output: Contribution to journalArticle

Postoperative Pain
Thoracic Surgery

Pre-TKR genicular nerve ablation

Walega, D., Mccormick, Z. & Avram, M., Jan 1 2020, In : Regional anesthesia and pain medicine. 45, 1, p. 91-92 2 p.

Research output: Contribution to journalLetter

Postoperative Pain
Chronic Pain
2 Citations (Scopus)
Knee Replacement Arthroplasties
Postoperative Pain
Randomized Controlled Trials
Opioid Analgesics
8 Citations (Scopus)

A Randomized Controlled Trial of Low-Dose Tranexamic Acid versus Placebo to Reduce Red Blood Cell Transfusion During Complex Multilevel Spine Fusion Surgery

Northwestern High Risk Spine Group, Feb 2018, In : World neurosurgery. 110, p. e572-e579

Research output: Contribution to journalArticle

Tranexamic Acid
Erythrocyte Transfusion
Randomized Controlled Trials