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Michael J Avram

  • 4628 Citations
1976 …2020

Research output per year

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Personal profile

Research Interests

Dr. Avram’s research interests include pharmacokinetics (PKs) and pharmacodynamics (PDs) of hypnotics, sedatives, opioids, analgesics, non-depolarizing neuromuscular blockers, chemotherapeutics, etc. His major research focus has been the development and evaluation of detailed PK models of rapidly acting intravanously administered drugs from the moment of injection to serve as the basis for understanding the PK basis of interindividual variability in response to these agents, which often have low clinical margins of safety.

Education/Academic qualification

PhD, Loyola University Chicago

… → 1980

Research interests

  • Aging
  • Anesthesiology
  • Clinical Pharmacology
  • Oncology
  • Pain Management
  • Pharmacokinetics
  • Pharmacology
  • Physiology

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Grants

Type-2 inflammation mediates olfactory loss in Chronic Rhinosinusitis: mechanisms and therapeutic opportunities

Avram, M. J., Chmiel, J. S., Schleimer, R. P. & Tan, B. K.

National Institute on Deafness and Other Communication Disorders

7/23/18 → 6/30/23

Project: Research project

    • Optimizing Pharmacotherapy for Depression during Pregnancy (OPTI-MOM)

    Avram, M. J., Ciolino, J. D., George Jr, A. L., Gollan, J. K., Grobman, W. A., Rasmussen-Torvik, L. J. & Wisner, K. L.

    National Institute of Child Health and Human Development

    8/1/15 → 6/30/21

    Project: Research project

    • A Multi Facility Mass Spectrometer for Targeted Quantitation Experiments

    Avram, M. J., Bass, J., Habibi Goudarzi, S., Kandela, I., Kelleher, N. L., Kiser, P., Krejcie, T. C., Mazar, A. P., Ott, A. W., Schiltz, G. E., Siddique, T., Thomas, P. M., Tyo, K. E. J., Wainwright, D. A., Watterson, D. M. & Woodruff, T. K.

    Office of the Director, National Institutes of Health

    7/15/16 → 7/14/18

    Project: Research project

    • High Density Lipoprotein Nanoparticles for siRNA Delivery

    Avram, M. J., Thaxton, C. S. & Volpert, O.

    National Cancer Institute

    7/1/16 → 6/30/18

    Project: Research project

    Ex Vivo Female Reproductive Tract Integration In a 3D Microphysiologic System

    Avram, M. J., Hope, T. J., Kim, J. J., Pavone, M. & Woodruff, T. K.

    National Center for Advancing Translational Sciences

    9/18/14 → 12/31/17

    Project: Research project

    Research Output

    Microbiota composition modulates inflammation and neointimal hyperplasia after arterial angioplasty

    Cason, C. A., Kuntz, T. M., Chen, E. B., Wun, K., Nooromid, M. J., Xiong, L., Gottel, N. R., Harris, K. G., Morton, T. C., Avram, M. J., Chang, E. B., Gilbert, J. A. & Ho, K. J., Apr 2020, In : Journal of Vascular Surgery. 71, 4, p. 1378-1389.e3

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Pharmacokinetic studies in pregnancy

    Avram, M. J., Jan 1 2020, (Accepted/In press) In : Seminars in Perinatology. 151227.

    Research output: Contribution to journal › Review article

    • Postoperative Pain and Analgesic Requirements in the First Year after Intraoperative Methadone for Complex Spine and Cardiac Surgery

    Murphy, G. S., Avram, M. J., Greenberg, S. B., Shear, T. D., Deshur, M. A., Dickerson, D., Bilimoria, S., Benson, J., Maher, C. E., Trenk, G. J., Teister, K. J. & Szokol, J. W., Feb 1 2020, In : Anesthesiology. 132, 2, p. 330-342 13 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Pre-TKR genicular nerve ablation

    Walega, D., Mccormick, Z. & Avram, M., Jan 1 2020, In : Regional anesthesia and pain medicine. 45, 1, p. 91-92 2 p.

    Research output: Contribution to journal › Letter

    Rational Perioperative Opioid Management in the Era of the Opioid Crisis

    Kharasch, E. D., Avram, M. J. & Clark, J. D., Apr 1 2020, In : Anesthesiology. 132, 4, p. 603-605 3 p.

    Research output: Contribution to journal › Article

    1 Scopus citations