Grants per year
Personal profile
Research Interests
Dr. Avram’s research interests include pharmacokinetics (PKs) and pharmacodynamics (PDs) of hypnotics, sedatives, opioids, analgesics, non-depolarizing neuromuscular blockers, chemotherapeutics, etc. His major research focus has been the development and evaluation of detailed PK models of rapidly acting intravanously administered drugs from the moment of injection to serve as the basis for understanding the PK basis of interindividual variability in response to these agents, which often have low clinical margins of safety.
Education/Academic qualification
Pharmacology and Experimental Therapeutics, PhD, Loyola University - Chicago
… → 1980
Research interests keywords
- Aging
- Anesthesiology
- Clinical Pharmacology
- Oncology
- Pain Management
- Pharmacokinetics
- Pharmacology
- Physiology
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Collaborations and top research areas from the last five years
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ENDEAVOR TO STOP NAUSEA/VOMITING ASSOCIATED WITH PREGNANCY (E-SNAP)
Wisner, K. L., Avram, M. J., Kim, K. A. & Stika, C. S.
National Institute of Child Health and Human Development
6/13/22 → 5/31/24
Project: Research project
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A Multi Facility Mass Spectrometer for Targeted Quantitation Experiments
Habibi Goudarzi, S., Ott, A. W., Avram, M. J., Bass, J., Kelleher, N. L., Kiser, P., Krejcie, T. C., Mazar, A. P., Schiltz, G. E., Siddique, T., Thomas, P. M., Tyo, K. E. J., Wainwright, D. A., Watterson, D. M. & Woodruff, T. K.
Office of the Director, National Institutes of Health
7/15/16 → 7/14/18
Project: Research project
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High Density Lipoprotein Nanoparticles for siRNA Delivery
Thaxton, C. S., Avram, M. J. & Volpert, O.
7/1/16 → 6/30/18
Project: Research project
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Optimizing Pharmacotherapy for Depression during Pregnancy (OPTI-MOM)
Wisner, K. L., George, A. L., Avram, M. J., Ciolino, J. D., Gollan, J. K., Grobman, W. A. & Rasmussen-Torvik, L. J.
National Institute of Child Health and Human Development
8/1/15 → 6/30/21
Project: Research project
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A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2-positive) cancer with leptomeningeal metastases: Safety, efficacy, and cerebrospinal fluid pharmacokinetics
Kumthekar, P. U., Avram, M. J., Lassman, A. B., Lin, N. U., Lee, E., Grimm, S. A., Schwartz, M., Bell Burdett, K. L., Lukas, R. V., Dixit, K., Perron, I., Zhang, H., Gradishar, W. J., Pentsova, E. I., Jeyapalan, S., Groves, M. D., Melisko, M. & Raizer, J. J., Mar 14 2023, In: Neuro-oncology. 25, 3, p. 557-565 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Changes in Sertraline Plasma Concentrations Across Pregnancy and Postpartum
Stika, C. S., Wisner, K. L., George, A. L., Avram, M. J., Zumpf, K., Rasmussen-Torvik, L. J., Mesches, G. A., Caritis, S. N., Venkataramanan, R., Costantine, M. M., West, H. A., Clark, S. & Ciolino, J. D., Dec 2022, In: Clinical pharmacology and therapeutics. 112, 6, p. 1280-1290 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Elimination Clearance of Dexmedetomidine: Cross-examining What the Data Say
Henthorn, T. K., Krejcie, T. C. & Avram, M. J., Feb 1 2022, In: Anesthesiology. 136, 2, p. 258-260 3 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Lithium Pharmacokinetics in the Perinatal Patient With Bipolar Disorder
Clark, C. T., Newmark, R. L., Wisner, K. L., Stika, C. & Avram, M. J., Nov 2022, In: Journal of Clinical Pharmacology. 62, 11, p. 1385-1392 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Trajectories of Depressive and Anxiety Symptoms Across Pregnancy and Postpartum in Selective Serotonin Reuptake Inhibitor-Treated Women
Mesches, G. A., Ciolino, J. D., Stika, C. S., Sit, D. K. Y., Zumpf, K., Fisher, S. D., Clark, C. T., George, A. L., Avram, M. J., Rasmussen-Torvik, L. J., Erickson, D. L., Caritis, S., Fischer, D., Venkataramanan, R., Costantine, M., West, H., Welch, E., Clark, S., Wisner, K. L. & Gollan, J. K., Jun 1 2022, In: Psychiatric Research and Clinical Practice. 4, 2, p. 32-41 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations