Grants per year
Personal profile
Research Interests
Dr. Avram’s research interests include pharmacokinetics (PKs) and pharmacodynamics (PDs) of hypnotics, sedatives, opioids, analgesics, non-depolarizing neuromuscular blockers, chemotherapeutics, etc. His major research focus has been the development and evaluation of detailed PK models of rapidly acting intravanously administered drugs from the moment of injection to serve as the basis for understanding the PK basis of interindividual variability in response to these agents, which often have low clinical margins of safety.
Education/Academic qualification
PhD, Loyola University-Chicago
… → 1980
Research interests
- Aging
- Anesthesiology
- Clinical Pharmacology
- Oncology
- Pain Management
- Pharmacokinetics
- Pharmacology
- Physiology
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Pharmacokinetics
Medicine & Life Sciences
Indocyanine Green
Medicine & Life Sciences
Pharmaceutical Preparations
Medicine & Life Sciences
Anesthesia
Medicine & Life Sciences
Antipyrine
Medicine & Life Sciences
Fentanyl
Medicine & Life Sciences
Cardiac Output
Medicine & Life Sciences
Thiopental
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2006 2023
Type-2 inflammation mediates olfactory loss in Chronic Rhinosinusitis: mechanisms and therapeutic opportunities
Avram, M. J., Chmiel, J. S., Schleimer, R. P. & Tan, B. K.
National Institute on Deafness and Other Communication Disorders
7/23/18 → 6/30/23
Project: Research project
Smell
Inflammation
Proton-Translocating ATPases
Therapeutics
Ion Pumps
Optimizing Pharmacotherapy for Depression during Pregnancy (OPTI-MOM)
Avram, M. J., Ciolino, J. D., George Jr, A. L., Gollan, J. K., Grobman, W. A., Rasmussen-Torvik, L. J. & Wisner, K. L.
National Institute of Child Health and Human Development
8/1/15 → 6/30/20
Project: Research project
Depression
Drug Therapy
Pregnancy
Postpartum Period
Health Priorities
A Multi Facility Mass Spectrometer for Targeted Quantitation Experiments
Avram, M. J., Bass, J., Habibi Goudarzi, S., Kandela, I., Kelleher, N. L., Kiser, P., Krejcie, T. C., Mazar, A. P., Ott, A. W., Schiltz, G. E., Siddique, T., Thomas, P. M., Tyo, K. E. J., Wainwright, D. A., Watterson, D. M. & Woodruff, T. K.
Office of the Director, National Institutes of Health
7/15/16 → 7/14/18
Project: Research project
Mass spectrometers
Metabolites
Experiments
High pressure liquid chromatography
Ions
High Density Lipoprotein Nanoparticles for siRNA Delivery
Avram, M. J., Thaxton, C. S. & Volpert, O.
7/1/16 → 6/30/18
Project: Research project
Ex Vivo Female Reproductive Tract Integration In a 3D Microphysiologic System
Avram, M. J., Hope, T. J., Kim, J. J., Pavone, M. & Woodruff, T. K.
National Center for Advancing Translational Sciences
9/18/14 → 12/31/17
Project: Research project
Research Output 1976 2019
Pre-TKR genicular nerve ablation
Walega, D. R., McCormick, Z. & Avram, M. J., Jan 1 2019, (Accepted/In press) In : Regional anesthesia and pain medicine.Research output: Contribution to journal › Letter
Postoperative Pain
Chronic Pain
Knee
2
Citations
(Scopus)
Radiofrequency ablation of genicular nerves prior to total knee replacement has no effect on postoperative pain outcomes: A prospective randomized sham-controlled trial with 6-month follow-up
Walega, D. R., McCormick, Z., Manning, D. W. & Avram, M. J., Jun 1 2019, In : Regional anesthesia and pain medicine. 44, 6, p. 646-651 6 p.Research output: Contribution to journal › Article
Knee Replacement Arthroplasties
Postoperative Pain
Knee
Randomized Controlled Trials
Opioid Analgesics
7
Citations
(Scopus)
A Randomized Controlled Trial of Low-Dose Tranexamic Acid versus Placebo to Reduce Red Blood Cell Transfusion During Complex Multilevel Spine Fusion Surgery
Northwestern High Risk Spine Group, Feb 1 2018, In : World Neurosurgery. 110, p. e572-e579Research output: Contribution to journal › Article
Tranexamic Acid
Erythrocyte Transfusion
Spine
Randomized Controlled Trials
Placebos
Combined Recirculatory-compartmental Population Pharmacokinetic Modeling of Arterial and Venous Plasma S(+) and R(–) Ketamine Concentrations
Henthorn, T. K., Avram, M. J., Dahan, A., Gustafsson, L. L., Persson, J., Krejcie, T. C. & Olofsen, E., Aug 1 2018, In : Anesthesiology. 129, 2, p. 260-270 11 p.Research output: Contribution to journal › Article
Ketamine
Pharmacokinetics
Arm
Pharmaceutical Preparations
Population
4
Citations
(Scopus)
Comparison of the TOFscan and the TOF-Watch SX during recovery of neuromuscular function
Murphy, G. S., Szokol, J. W., Avram, M. J., Greenberg, S. B., Shear, T. D., Deshur, M., Benson, J., Newmark, R. L. & Maher, C. E., Jan 1 2018, In : Anesthesiology. 129, 5, p. 880-888 9 p.Research output: Contribution to journal › Article
Recovery of Function
Neuromuscular Blockade
Equipment and Supplies
Calibration
Neuromuscular Monitoring