Grants per year
Personal profile
Research Interests
I am committed to a career in patient-oriented research related to pulmonary vascular disease. Exploring the clinical impact and the mechanisms of pulmonary hypertension (PH) in patients with underlying lung disease is my primary research interest. This interest stems from my clinical experience over the last several years developing and building the Northwestern Pulmonary Hypertension Program. Pulmonary hypertension is a common complication seen in patients with lung disease, specifically chronic obstructive pulmonary disease (COPD). Although the association between the presence of PH in COPD and increased mortality has been well described, we have recently explored the impact of PH on patient-centered outcomes. I am interested in exploring the mechanisms of PH and identifying the disease as it presents early in the course of lung disease when interventions could potentially alter disease progression.
Certifications and Licenses
Critical Care Medicine | |
Pulmonary Disease | |
Internal Medicine |
Training Experience
2004 | Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital) |
2005 | Fellowship, National Institutes of Health |
2006 | Fellowship, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital) |
2008 | Fellowship, National Institutes of Health |
Education/Academic qualification
Medicine, MD, Northwestern University
… → 2001
Research interests keywords
- Chronic Obstructive Pulmonary Disease (COPD)
- Pulmonary Hypertension
- Pulmonary Thromboembolism
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Prot #CS1-003: A Phase 2, Prospective, Randomized, Open-label, Blinded Endpoint, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of 3 Doses of CS1 in Subjects with Pulmonary Arterial Hypertension
Worldwide Clinical Trials, Inc., Cereno Scientific AB
12/7/22 → 12/7/25
Project: Research project
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Prot #INS1009-202: A Phase 2b, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Arterial Hypertension
PPD Development, Insmed Incorporated
4/1/22 → 4/1/25
Project: Research project
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Prot #67896062PAH4005: An International, Non-drug Interventional, Real-world Cohort of PAH Patients Newly Initiating PAH Therapy with Guideline Directed Assessments of Disease Severity: CARE PAH (Contemporary Real-World PAH Best Practice)
Parexel, Actelion Pharmaceuticals Ltd.
1/14/22 → 4/30/27
Project: Research project
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Prot #67896062CTP3001: Macitentan in Inoperable or Persistent/Recurrent Chronic ThromboEmbolic Pulmonary Hypertension (MACiTEPH): A Prospective, Randomized, Double-Blind, Multicenter, Placebo-Controlled, Parallel Group, Adaptive Phase 3 Study with Open-l
Janssen Research & Development, LLC
9/21/21 → 9/18/26
Project: Research project
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Case report: Multimodality imaging of unusual coronary to pulmonary collaterals in chronic thromboembolic pulmonary hypertension
Goyal, A., Avery, R., Cuttica, M. J., Flaherty, J. D., Malaisrie, S. C. & Mylvaganam, R., 2023, In: Frontiers in Cardiovascular Medicine. 10, 1204736.Research output: Contribution to journal › Article › peer-review
Open Access -
Differences in referral to a chronic thromboembolic pulmonary hypertension center following acute pulmonary embolism: a locoregional experience
Mylvaganam, R., Lawrence, R., Goldberg, I., Rahaghi, F., Chiu, S., Malaisrie, S. C., Schimmel, D., Avery, R., Martin, K. & Cuttica, M. J., May 2023, In: Journal of thrombosis and thrombolysis. 55, 4, p. 691-699 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Outcomes of Percutaneous Tracheostomy for Patients with SARS-CoV-2 Respiratory Failure
Arnold, J., Gao, C. A., Malsin, E., Todd, K., Argento, A. C., Cuttica, M., Coleman, J. M., Wunderink, R. G. & Smith, S. B., Jan 5 2023, In: Journal of Bronchology and Interventional Pulmonology. 30, 1, p. 60-65 6 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Inferior Vena Cava Thrombosis Risk in 1582 Patients with Inferior Vena Cava Filters
Xiao, N., Karp, J., Lewandowski, R., Cuttica, M., Schimmel, D., Martin, K. & Desai, K. R., May 2022, In: Radiology. 303, 2, p. 300-302 3 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Lung function impairment and risk of incident heart failure: the NHLBI Pooled Cohorts Study
Eckhardt, C. M., Balte, P. P., Barr, R. G., Bertoni, A. G., Bhatt, S. P., Cuttica, M., Cassano, P. A., Chaves, P., Couper, D., Jacobs, D. R., Kalhan, R., Kronmal, R., Lange, L., Loehr, L., London, S. J., O'connor, G. T., Rosamond, W., Sanders, J., Schwartz, J. E., Shah, A., & 5 others , Jun 14 2022, In: European heart journal. 43, 23, p. 2196-2208 13 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations
Datasets
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Relationship of left ventricular outflow tract velocity time integral to treatment strategy in submassive and massive pulmonary embolism
Antoine, D. (Creator), Chuich, T. (Creator), Mylvaganam, R. J. (Creator), Malaisrie, S. C. (Creator), Freed, B. H. (Creator), Cuttica, M. J. (Creator) & Schimmel, D. R. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5136393, https://sage.figshare.com/collections/Relationship_of_left_ventricular_outflow_tract_velocity_time_integral_to_treatment_strategy_in_submassive_and_massive_pulmonary_embolism/5136393
Dataset