Grants per year
Personal profile
Research Interests
I am committed to a career in patient-oriented research related to pulmonary vascular disease. Exploring the clinical impact and the mechanisms of pulmonary hypertension (PH) in patients with underlying lung disease is my primary research interest. This interest stems from my clinical experience over the last several years developing and building the Northwestern Pulmonary Hypertension Program. Pulmonary hypertension is a common complication seen in patients with lung disease, specifically chronic obstructive pulmonary disease (COPD). Although the association between the presence of PH in COPD and increased mortality has been well described, we have recently explored the impact of PH on patient-centered outcomes. I am interested in exploring the mechanisms of PH and identifying the disease as it presents early in the course of lung disease when interventions could potentially alter disease progression.
Certifications and Licenses
Critical Care Medicine | |
Pulmonary Disease | |
Internal Medicine |
Training Experience
2004 | Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital) |
2005 | Fellowship, National Institutes of Health |
2006 | Fellowship, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital) |
2008 | Fellowship, National Institutes of Health |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Northwestern University Feinberg School of Medicine
… → 2001
Research interests keywords
- Chronic Obstructive Pulmonary Disease (COPD)
- Pulmonary Hypertension
- Pulmonary Thromboembolism
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Collaborations and top research areas from the last five years
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TEAM Registry
Cuttica, M. J. (PD/PI)
International CTEPH Association
10/1/23 → 9/30/26
Project: Research project
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Prot #INS1009-203: An Open-Label Extension Study to Assess the Safety, Tolerability, and Effectiveness of the Long-Term use of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Arterial Hypertension
Cuttica, M. J. (PD/PI)
PPD Development, Insmed Incorporated
4/24/23 → 4/24/26
Project: Research project
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Prot #CS1-003: A Phase 2, Prospective, Randomized, Open-label, Blinded Endpoint, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of 3 Doses of CS1 in Subjects with Pulmonary Arterial Hypertension
Cuttica, M. J. (PD/PI)
Worldwide Clinical Trials, Inc., Cereno Scientific AB
12/7/22 → 12/7/25
Project: Research project
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Classification and Prognostication in Pulmonary Thromboembolism Using Computed Tomography Image Analytics
Cuttica, M. J. (PD/PI), Cuttica, M. J. (PD/PI), Mylvaganam, R. J. (Co-Investigator) & Mylvaganam, R. J. (Co-Investigator)
Brigham and Women’s Hospital, National Heart, Lung, and Blood Institute
9/1/22 → 6/30/27
Project: Research project
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Prot #INS1009-202: A Phase 2b, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Arterial Hypertension
Cuttica, M. J. (PD/PI)
PPD Development, Insmed Incorporated
4/1/22 → 4/1/25
Project: Research project
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Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension Secondary to Expanded Polytetrafluoroethylene Valved Pulmonary Conduit Thrombosis
Robinson, E., Logan, C., Chiu, S., Husain, N., Cuttica, M. J., Mongé, M. C. & Malaisrie, S. C., Mar 5 2025, In: JACC: Case Reports. 30, 5, 103069.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia
The NU SCRIPT Study Investigators, 2024, (Accepted/In press) In: Nature Immunology. 25, 9, p. 1607-1622 16 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Case report: Multimodality imaging of unusual coronary to pulmonary collaterals in chronic thromboembolic pulmonary hypertension
Goyal, A., Avery, R., Cuttica, M. J., Flaherty, J. D., Malaisrie, S. C. & Mylvaganam, R., 2023, In: Frontiers in Cardiovascular Medicine. 10, 1204736.Research output: Contribution to journal › Article › peer-review
Open Access -
Differences in referral to a chronic thromboembolic pulmonary hypertension center following acute pulmonary embolism: a locoregional experience
Mylvaganam, R., Lawrence, R., Goldberg, I., Rahaghi, F., Chiu, S., Malaisrie, S. C., Schimmel, D., Avery, R., Martin, K. A. & Cuttica, M. J., May 2023, In: Journal of thrombosis and thrombolysis. 55, 4, p. 691-699 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Outcomes of Percutaneous Tracheostomy for Patients with SARS-CoV-2 Respiratory Failure
Arnold, J., Gao, C. A., Malsin, E., Todd, K., Argento, A. C., Cuttica, M., Coleman, J. M., Wunderink, R. G. & Smith, S. B., Jan 5 2023, In: Journal of Bronchology and Interventional Pulmonology. 30, 1, p. 60-65 6 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Datasets
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Relationship of left ventricular outflow tract velocity time integral to treatment strategy in submassive and massive pulmonary embolism
Antoine, D. (Creator), Chuich, T. (Creator), Mylvaganam, R. (Creator), Malaisrie, C. (Creator), Freed, B. (Creator), Cuttica, M. (Creator) & Schimmel, D. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5136393, https://sage.figshare.com/collections/Relationship_of_left_ventricular_outflow_tract_velocity_time_integral_to_treatment_strategy_in_submassive_and_massive_pulmonary_embolism/5136393
Dataset