Grants per year
Personal profile
Research Interests
Dr. Markl is the Vice Chair for Research in the Department of Radiology at Northwestern University Feinberg School of Medicine. He received his PhD in Physics from the University of Freiburg, Germany (2000), and served as a postdoctoral fellow at the Lucas MRI/S Center at Stanford University, Radiology (2001-2004). In 2004, he returned to the University Hospital in Freiburg, Germany as the Director of Cardiovascular MRI. Dr. Markl has been on faculty at Northwestern since 2011 during which time he has been the Director of Cardiovascular Imaging Research and led Cardiovascular MR research in the Center for Translational Imaging, a Northwestern University core facility housed in Radiology. He is also the Lester B. and Frances T. Knight Professor of Cardiac Imaging in the Departments of Radiology and Biomedical Engineering at Northwestern University. A central objective of Dr. Markl's research program is to develop multi-parametric imaging techniques than can afford a better understanding of the underlying physiologic mechanisms of heart disease and stroke as well as the impact of therapy. The work of his research group has been instrumental in establishing '4D Flow MRI' for the comprehensive assessment of cardiovascular hemodynamics in heart disease and stroke. Further accomplishments include the development, validation, and application of novel imaging tools for the evaluation of structure and function of the heart. Clinical applications have provided new insights into the specific links between pathology, therapy, intervention and functional changes within the heart and cardiovascular system. To date, his accomplishments include a total of >280 peer-reviewed publications, 600+ conference abstracts, 10 book chapters, 10 patents, and >140 invited presentations. In addition, Dr. Markl has a track-record of external funding with over 20 awarded grants from the NIH, societies, and industry collaborations. He has a record of mentorship having trained over 75 medical and graduate students, postdocs, clinical fellows, and junior faculty. These trainees have received prestigious awards from the NIH, AHA, ISMRM, RSNA, and others and have successful careers in academia and industry. Dr. Markl is a recipient of the RSNA Research Trainee Prize, the I.I. Rabi Award Young Investigator Award of the ISMRM, and the Distinguished Investigator Award of the Academy of Radiology Research. He is a Member of the Editorial Boards of the ‘European Heart Journal - Cardiovascular Imaging’, 'JCMR', and 'Radiology - Cardiothoracic Imaging, a Fellow of the ISMRM and SCMR, a member of the Board of Trustees of the SCMR, and the President-of the Society for Magnetic Resonance Angiography (SMRA).
A central objective of Dr. Markl's research program is to develop multi-parametric imaging techniques than can afford a better understanding of the underlying physiologic mechanisms of heart disease and stroke as well as the impact of therapy. The work of his research group has been instrumental in establishing '4D Flow MRI' for the comprehensive assessment of cardiovascular hemodynamics in heart disease and stroke. Further accomplishments include the development, validation, and application of novel imaging tools for the evaluation of structure and function of the heart. Clinical applications have provided new insights into the specific links between pathology, therapy, intervention and functional changes within the heart and cardiovascular system.
Training Experience
2003 | Postdoctoral Fellowship, Stanford University |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, University of Freiburg
… → 2000
Research interests keywords
- Cardiovascular Diseases
- Cardiovascular Imaging
- Radiology
- Bioengineering
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Network
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State-of-the-art High Field 7T MRI System Upgrade to Accelerate Translational Sciences
Office of the Director, National Institutes of Health
4/1/23 → 3/31/24
Project: Research project
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Quantitative cerebral blood vessel imaging biomarkers for AD and VCID
Yan, L., Markl, M., Ragin, A. & Sorond, F. A.
2/1/23 → 3/31/24
Project: Research project
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Probing silent cerebral infarct pathogenesis in sickle cell disease with cerebrovascular MRI - F31 for Kristina Marie Zvolanek
1/15/23 → 1/14/24
Project: Research project
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Rapid Cardiovascular MRI for Screening Microvascular Angina in COVID-19 Survivors
Kim, D., Lee, D. C., Allen, B. D., Ison, M. G., Kalhan, R. & Markl, M.
4/1/22 → 3/31/25
Project: Research project
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Motion Resistance Artificial Subtraction Angiography with Deep Learning
Cantrell, D. R., Ansari, S. A., Bagci, U. & Markl, M.
4/1/22 → 3/31/25
Project: Research project
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A Left ventricle remodeling in patients with bicuspid aortic valve
Suwa, K., Rahsepar, A. A., Geiger, J., Dolan, R., Ghasemiesfe, A., Barker, A. J., Collins, J. D., Markl, M. & Carr, J. C., Feb 2023, In: International Journal of Cardiovascular Imaging. 39, 2, p. 391-399 9 p.Research output: Contribution to journal › Article › peer-review
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Comparison of Improved Unidirectional Dual Velocity-Encoding MRI Methods
Franco, P., Ma, L., Schnell, S., Carrillo, H., Montalba, C., Markl, M., Bertoglio, C. & Uribe, S., Mar 2023, In: Journal of Magnetic Resonance Imaging. 57, 3, p. 763-773 11 p.Research output: Contribution to journal › Article › peer-review
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Entry Tear Hemodynamics Detect Patients With Adverse Aorta-Related Outcomes in Type B Aortic Dissection
Allen, B. D., Kilinc, O., Pradella, M., Chu, S., Mehta, C. K., Malaisrie, S. C., Hoel, A. W., Carr, J. C. & Markl, M., May 2023, In: JACC: Cardiovascular Imaging. 16, 5, p. 711-712 2 p.Research output: Contribution to journal › Letter › peer-review
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Entry tear hemodynamics using 4D flow MRI in a patient with acute type B aortic dissection
Liu, S. Z., Engel, J. S., Bisen, J. B., Kilinc, O., Quinn, S., Hoel, A. W., Mehta, C. K., Markl, M. & Allen, B. D., Mar 2023, In: Radiology Case Reports. 18, 3, p. 1037-1040 4 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Fully-automated deep learning-based flow quantification of 2D CINE phase contrast MRI
Pradella, M., Scott, M. B., Omer, M., Hill, S. K., Lockhart, L., Yi, X., Amir-Khalili, A., Sojoudi, A., Allen, B. D., Avery, R. & Markl, M., Mar 2023, In: European Radiology. 33, 3, p. 1707-1718 12 p.Research output: Contribution to journal › Article › peer-review
Open Access