Michael Sean Carroll

  • 337 Citations
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research Interests

My research is aimed at using computational methods to derive insight from large physiological datasets generated in clinical practice, with particular focus on pediatric autonomic and respiratory disorders, but recently expanding into critical care. My work has included familial dysautonomia, congenital central hypoventilation syndrome (CCHS), rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD), Rett syndrome and other pediatric disorders. My combined fluency with basic science, clinical and mathematical concepts inspires an eclectic and inclusive approach to discovery. Preferred quantitative tools span a wide range from traditional statistics through machine learning, network theory and dynamical system simulation. Nevertheless, these techniques are secondary to the central goal of understanding the physiological phenotype and underlying mechanisms of pediatric disorders, with the ultimate desire to improve patient care. I am also profoundly interested in bringing clinical physiology into the modern computational era by developing analytics and visualization systems that could provide physicians with tools to accelerate research, reduce healthcare costs and save lives. Such systems would be deeply transformative in specialty areas such as sleep medicine, neurophysiology, critical care, and of course, autonomic medicine. I’m currently collaborating with several physicians in critical care at Lurie to secure funding for continued development and further deployment of a visual analytics system to improve clinician situational awareness and patient monitoring in that department. For that project, I will be contributing to the development of physiologically relevant metrics and intuitive visualization techniques to facilitate important clinical decisions.

Education/Academic qualification

PhD, University of Chicago

… → 2009

Fingerprint Dive into the research topics where Michael Sean Carroll is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Hypoventilation Medicine & Life Sciences
Autonomic Nervous System Medicine & Life Sciences
Homeobox Genes Medicine & Life Sciences
Obesity Medicine & Life Sciences
Skin Temperature Medicine & Life Sciences
Familial Dysautonomia Medicine & Life Sciences
Respiration Medicine & Life Sciences
Hypercapnia Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2012 2021

Research Output 2002 2019

1 Citation (Scopus)

Heart rate variability as a marker of recovery from critical illness in children

Marsillio, L. E., Manghi, T., Carroll, M. S., Balmert, L. C. & Wainwright, M. S., May 2019, In : PloS one. 14, 5, e0215930.

Research output: Contribution to journalArticle

Open Access
Critical Illness
heart rate
Heart Rate
Intensive care units
2 Citations (Scopus)

Novel methods of imaging and analysis for the thermoregulatory sweat test

Carroll, M. S., Reed, D. W., Kuntz, N. L. & Weese-Mayer, D. E., Sep 2018, In : Journal of applied physiology. 125, 3, p. 755-762 8 p.

Research output: Contribution to journalArticle

Hot Temperature
Autonomic Pathways
14 Citations (Scopus)

Congenital central hypoventilation syndrome: A bedside-to-bench success story for advancing early diagnosis and treatment and improved survival and quality of life

Weese-Mayer, D. E., Rand, C. M., Zhou, A., Carroll, M. S. & Hunt, C. E., Jan 1 2017, In : Pediatric research. 81, 1-2, p. 192-201 10 p.

Research output: Contribution to journalReview article

Early Diagnosis
Quality of Life
Autonomic Nervous System
Homeobox Genes
10 Citations (Scopus)

Congenital central hypoventilation syndrome (CCHS): Circadian temperature variation

Saiyed, R., Rand, C. M., Carroll, M. S., Koliboski, C. M., Stewart, T. M., Brogadir, C. D., Kenny, A. S., Petersen, E. K. E., Carley, D. W. & Weese-Mayer, D. E., Mar 1 2016, In : Pediatric Pulmonology. 51, 3, p. 300-307 8 p.

Research output: Contribution to journalArticle

Skin Temperature
Body Temperature
Autonomic Nervous System
Circadian Rhythm
9 Citations (Scopus)

Determining peripheral skin temperature: Subjective versus objective measurements

Tse, J., Rand, C., Carroll, M., Charnay, A., Gordon, S., Morales, B., Vitez, S., Le, M. & Weese-Mayer, D., Mar 1 2016, In : Acta Paediatrica, International Journal of Paediatrics. 105, 3, p. e126-e131

Research output: Contribution to journalArticle

Skin Temperature
Equipment and Supplies
Delivery of Health Care