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3-Hydroxypyridin-2-thione as Novel Zinc Binding Group for Selective Histone Deacetylase Inhibition

Patil, V., Sodji, Q. H., Kornacki, J. R., Mrksich, M. & Oyelere, A. K., May 9 2013, In : Journal of Medicinal Chemistry. 56, 9, p. 3492-3506 15 p.

Research output: Contribution to journalArticle

52 Scopus citations

A bio-mechanical model for coupling cell contractility with focal adhesion formation

Deshpande, V. S., Mrksich, M., McMeeking, R. M. & Evans, A. G., Apr 1 2008, In : Journal of the Mechanics and Physics of Solids. 56, 4, p. 1484-1510 27 p.

Research output: Contribution to journalArticle

110 Scopus citations

A Bottom-Up Proteomic Approach to Identify Substrate Specificity of Outer-Membrane Protease OmpT

Wood, S. E., Sinsinbar, G., Gudlur, S., Nallani, M., Huang, C. F., Liedberg, B. & Mrksich, M., Dec 22 2017, In : Angewandte Chemie - International Edition. 56, 52, p. 16531-16535 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

A calcium-modulated plasmonic switch

Hall, W. P., Anker, J. N., Lin, Y., Modica, J., Mrksich, M. & Van Duyne, R. P., May 7 2008, In : Journal of the American Chemical Society. 130, 18, p. 5836-5837 2 p.

Research output: Contribution to journalArticle

80 Scopus citations

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

Kightlinger, W., Duncker, K. E., Ramesh, A., Thames, A. H., Natarajan, A., Stark, J. C., Yang, A., Lin, L., Mrksich, M., DeLisa, M. P. & Jewett, M. C., Dec 1 2019, In : Nature communications. 10, 1, 5404.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Acetyltransferase p300/CBP associated factor (PCAF) regulates crosstalk-dependent acetylation of histone H3 by distal site recognition

Kornacki, J. R., Stuparu, A. D. & Mrksich, M., Jan 16 2015, In : ACS chemical biology. 10, 1, p. 157-164 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
435 Scopus citations

A conformation- and ion-sensitive plasmonic biosensor

Hall, W. P., Modica, J., Anker, J., Lin, Y., Mrksich, M. & Van Duyne, R. P., Mar 9 2011, In : Nano letters. 11, 3, p. 1098-1105 8 p.

Research output: Contribution to journalArticle

93 Scopus citations

Active Site Metal Identity Alters Histone Deacetylase 8 Substrate Selectivity: A Potential Novel Regulatory Mechanism

Castaneda, C. A., Lopez, J. E., Joseph, C. G., Scholle, M. D., Mrksich, M. & Fierke, C. A., Oct 24 2017, In : Biochemistry. 56, 42, p. 5663-5670 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Adsorption of proteins to hydrophobic sites on mixed self-assembled monolayers

Ostuni, E., Grzybowski, B. A., Mrksich, M., Roberts, C. S. & Whitesides, G. M., Mar 4 2003, In : Langmuir. 19, 5, p. 1861-1872 12 p.

Research output: Contribution to journalArticle

213 Scopus citations

Affinity capillary electrophoresis: Using capillary electrophoresis to study the interactions of proteins with ligands

Gao, J., Mrksich, M., Mammen, M. & Whitesides, G. M., Dec 1 1998, In : Chemical Analysis. 146, p. 947-972 26 p.

Research output: Contribution to journalArticle

4 Scopus citations

A gene expression-based comparison of cell adhesion to extracellular matrix and RGD-terminated monolayers

Sobers, C. J., Wood, S. E. & Mrksich, M., 2015, In : Biomaterials. 52, 1, p. 385-394 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

A high-throughput SAMDI-mass spectrometry assay for isocitrate dehydrogenase 1

Anderson, S. E., Fahey, N. S., Park, J., O'Kane, P. T., Mirkin, C. A. & Mrksich, M., Jun 7 2020, In : Analyst. 145, 11, p. 3899-3908 10 p.

Research output: Contribution to journalArticle

A method for connecting solution-phase enzyme activity assays with immobilized format analysis by mass spectrometry

Min, D. H., Yeo, W. S. & Mrksich, M., Jul 15 2004, In : Analytical Chemistry. 76, 14, p. 3923-3929 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

An adaptor domain-mediated autocatalytic interfacial kinase reaction

Liao, X., Su, J. & Mrksich, M., Dec 4 2009, In : Chemistry - A European Journal. 15, 45, p. 12303-12309 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

An Assay Based on SAMDI Mass Spectrometry for Profiling Protein Interaction Domains

O'Kane, P. T. & Mrksich, M., Aug 2 2017, In : Journal of the American Chemical Society. 139, 30, p. 10320-10327 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

An Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products

Grant, J., Modica, J. A., Roll, J., Perkovich, P. & Mrksich, M., Aug 2 2018, In : Small. 14, 31, 1800923.

Research output: Contribution to journalArticle

5 Scopus citations

An inhibitor of a cell adhesion receptor stimulates cell migration

Shabbir, S. H., Eisenberg, J. L. & Mrksich, M., Oct 11 2010, In : Angewandte Chemie - International Edition. 49, 42, p. 7706-7709 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

Antibody arrays prepared by cutinase-mediated immobilization on self-assembled monolayers

Kwon, Y., Han, Z., Karatan, E., Mrksich, M. & Kay, B. K., Oct 1 2004, In : Analytical Chemistry. 76, 19, p. 5713-5720 8 p.

Research output: Contribution to journalArticle

104 Scopus citations
210 Scopus citations
106 Scopus citations

An Unusual Salt Effect in an Interfacial Nucleophilic Substitution Reaction

Li, S. & Mrksich, M., Jun 12 2018, In : Langmuir. 34, 23, p. 6713-6718 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

A photochemical method for patterning the immobilization of ligands and cells to self-assembled monolayers

Dillmore, W. S., Yousaf, M. N. & Mrksich, M., Aug 17 2004, In : Langmuir. 20, 17, p. 7223-7231 9 p.

Research output: Contribution to journalArticle

158 Scopus citations

A self-adjuvanting supramolecular vaccine carrying a folded protein antigen

Hudalla, G. A., Modica, J. A., Tian, Y. F., Rudra, J. S., Chong, A. S., Sun, T., Mrksich, M. & Collier, J. H., Aug 2013, In : Advanced Healthcare Materials. 2, 8, p. 1114-1119 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

A spatially propagating biochemical reaction

Liao, X., Petty, R. T. & Mrksich, M., Jan 17 2011, In : Angewandte Chemie - International Edition. 50, 3, p. 706-708 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Assays of endogenous caspase activities: A comparison of mass spectrometry and fluorescence formats

Su, J., Rajapaksha, T. W., Peter, M. E. & Mrksich, M., Jul 15 2006, In : Analytical Chemistry. 78, 14, p. 4945-4951 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities

Tapadar, S., Fathi, S., Raji, I., Omesiete, W., Kornacki, J. R., Mwakwari, S. C., Miyata, M., Mitsutake, K., Li, J. D., Mrksich, M. & Oyelere, A. K., Dec 15 2015, In : Bioorganic and Medicinal Chemistry. 23, 24, p. 7543-7564 22 p.

Research output: Contribution to journalArticle

9 Scopus citations

A substituent effects study reveals the kinetic pathway for an interfacial reaction

Gawalt, E. S. & Mrksich, M., Dec 1 2004, In : Journal of the American Chemical Society. 126, 47, p. 15613-15617 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Attachment of cells to islands presenting gradients of adhesion ligands

Petty, R. T., Li, H. W., Maduram, J. H., Ismagilov, R. & Mrksich, M., Jul 25 2007, In : Journal of the American Chemical Society. 129, 29, p. 8966-8967 2 p.

Research output: Contribution to journalArticle

53 Scopus citations

Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase

Raji, I., Yadudu, F., Janeira, E., Fathi, S., Szymczak, L., Kornacki, J. R., Komatsu, K., Li, J. D., Mrksich, M. & Oyelere, A. K., 2017, In : Bioorganic and Medicinal Chemistry. 25, 3, p. 1202-1218 17 p.

Research output: Contribution to journalArticle

11 Scopus citations
95 Scopus citations

Biochemical assays of immobilized oligonucleotides with mass spectrometry

Tsubery, H. & Mrksich, M., May 20 2008, In : Langmuir. 24, 10, p. 5433-5438 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Biospecific Adsorption of Carbonic Anhydrase to Self-Assembled Monolayers of Alkanethiolates That Present Benzenesulfonamide Groups on Gold

Mrksich, M., Grunwell, J. R. & Whitesides, G. M., Jan 1 1995, In : Journal of the American Chemical Society. 117, 48, p. 12009-12010 2 p.

Research output: Contribution to journalArticle

177 Scopus citations

Bisboronic Acids for Selective, Physiologically Relevant Direct Glucose Sensing with Surface-Enhanced Raman Spectroscopy

Sharma, B., Bugga, P., Madison, L. R., Henry, A. I., Blaber, M. G., Greeneltch, N. G., Chiang, N., Mrksich, M., Schatz, G. C. & Van Duyne, R. P., Oct 26 2016, In : Journal of the American Chemical Society. 138, 42, p. 13952-13959 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells

Schumann, B., Malaker, S. A., Wisnovsky, S. P., Debets, M. F., Agbay, A. J., Fernandez, D., Wagner, L. J. S., Lin, L., Li, Z., Choi, J., Fox, D. M., Peh, J., Gray, M. A., Pedram, K., Kohler, J. J., Mrksich, M. & Bertozzi, C. R., Jun 4 2020, In : Molecular cell. 78, 5, p. 824-834.e15

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Cancer prognostics by direct detection of p53-antibodies on gold surfaces by impedance measurements

Prats-Alfonso, E., Sisquella, X., Zine, N., Gabriel, G., Guimerà, A., Del Campo, F. J., Villa, R., Eisenberg, A. H., Mrksich, M., Errachid, A., Aguiló, J. & Albericio, F., Jul 9 2012, In : Small. 8, 13, p. 2106-2115 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Carbohydrate arrays for the evaluation of protein binding and enzymatic modification

Houseman, B. T. & Mrksich, M., May 7 2002, In : Chemistry and Biology. 9, 4, p. 443-454 12 p.

Research output: Contribution to journalArticle

465 Scopus citations

Catalytic asymmetric dihydroxylation by gold colloids functionalized with self-assembled monolayers

Li, H., Luk, Y. Y. & Mrksich, M., Jul 20 1999, In : Langmuir. 15, 15, p. 4957-4959 3 p.

Research output: Contribution to journalArticle

109 Scopus citations

Cell adhesion to unnatural ligands mediated by a bifunctional protein

Sánchez-Cortés, J., Bähr, K. & Mrksich, M., Jul 21 2010, In : Journal of the American Chemical Society. 132, 28, p. 9733-9737 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Cellular Assays with a Molecular Endpoint Measured by SAMDI Mass Spectrometry

Berns, E. J., Cabezas, M. D. & Mrksich, M., Jul 1 2016, In : Small (Weinheim an der Bergstrasse, Germany). 12, 28, p. 3811-3818 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor

Min, D. H., Tang, W. J. & Mrksich, M., Jun 1 2004, In : Nature biotechnology. 22, 6, p. 717-723 7 p.

Research output: Contribution to journalArticle

126 Scopus citations

Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

Bien, C., Affinati, A. H., Ramsey, K. M., Kuo, H. Y., Yu, W., Sena, L. A., Ilkayeva, O., Marcheva, B., Kobayashi, Y., Omura, C., Levine, D. C., Bacsik, D. J., Gius, D. R., Newgard, C. B., Goetzman, E., Chandel, N., Denu, J. M., Mrksich, M. & Bass, J., 2013, In : Science. 342, 6158, 1243417.

Research output: Contribution to journalArticle

347 Scopus citations

Combining carbochips and mass spectrometry to study the donor specificity for the Neisseria meningitidis β1,3-N-acetylglucosaminyltransferase LgtA

Guan, W., Ban, L., Cai, L., Li, L., Chen, W., Liu, X., Mrksich, M. & Wang, P. G., Sep 1 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 17, p. 5025-5028 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Combining mass spectrometry and peptide arrays to profile the specificities of histone deacetylases

Gurard-Levin, Z. A., Kim, J. & Mrksich, M., Sep 4 2009, In : ChemBioChem. 10, 13, p. 2159-2161 3 p.

Research output: Contribution to journalArticle

46 Scopus citations

Combining microfluidic networks and peptide arrays for multi-enzyme assays

Su, J., Bringer, M. R., Ismagilov, R. F. & Mrksich, M., May 25 2005, In : Journal of the American Chemical Society. 127, 20, p. 7280-7281 2 p.

Research output: Contribution to journalArticle

68 Scopus citations

Controlling cell attachment on contoured surfaces with self-assembled monolayers of alkanethiolates on gold

Mrksich, M., Chen, C. S., Xia, Y., Dike, L. E., Ingber, D. E. & Whitesides, G. M., Oct 1 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 20, p. 10775-10778 4 p.

Research output: Contribution to journalArticle

378 Scopus citations

De novo motif for kinase mediated signaling across the cell membrane

Petty, R. T. & Mrksich, M., Aug 1 2011, In : Integrative Biology. 3, 8, p. 816-822 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
92 Scopus citations

Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids

Sodji, Q. H., Kornacki, J. R., McDonald, J. F., Mrksich, M. & Oyelere, A. K., May 26 2015, In : European Journal of Medicinal Chemistry. 96, p. 340-359 20 p.

Research output: Contribution to journalArticle

19 Scopus citations

Design and Synthesis of Megamolecule Mimics of a Therapeutic Antibody

Modica, J. A., Iderzorig, T. & Mrksich, M., Aug 12 2020, In : Journal of the American Chemical Society. 142, 32, p. 13657-13661 5 p.

Research output: Contribution to journalArticle