Grants per year
Personal profile
Research Interests
The Perera laboratory focuses on pharmacogenomics (using a patient's genome to predict drug response) in minority populations. Working in this translation research space requires both clinical expertise as well as the use of high-throughput basic science approaches. Our goal is to bring the benefits of precision medicine to all US populations.
Training Experience
2006 | Postdoctoral Fellowship, University of Chicago |
Education/Academic qualification
PhD, Pharmaceutics, Ohio State University
… → 2003
Pharmacology, PharmD, University of Tennessee
… → 2001
Research interests keywords
- Adverse Drug Reactions
- Autoimmune Diseases
- Gene Regulation
- Genomic Medicine/Personalized Medicine
- Inflammatory Bowel Disease
- Pharmacogenomics
- Pharmacology
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Collaborations and top research areas from the last five years
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Leveraging the Microbiome, Local Admixture, and Machine Learning to Optimize Anticoagulant Pharmacogenomics in Medically Underserved Patients
Perera, M. (PD/PI) & Perera, M. (PD/PI)
University of Arizona, National Heart, Lung, and Blood Institute
8/1/21 → 5/31/26
Project: Research project
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Northwestern Genomic Risk Assessment and Management Program
Chisholm, R. L. (PD/PI), Chisholm, R. L. (PD/PI), McNally, E. M. (PD/PI), McNally, E. M. (PD/PI), Rasmussen-Torvik, L. J. (PD/PI), Rasmussen-Torvik, L. J. (PD/PI), Gordon, A. S. (Co-Investigator), Gordon, A. S. (Co-Investigator), Kho, A. N. (Co-Investigator), Kho, A. N. (Co-Investigator), Luo, Y. (Co-Investigator), Luo, Y. (Co-Investigator), Perera, M. (Co-Investigator), Perera, M. (Co-Investigator), Roy-Puckelwartz, M. J. (Co-Investigator), Roy-Puckelwartz, M. J. (Co-Investigator), Scherr, C. E. L. (Co-Investigator), Scherr, C. E. L. (Co-Investigator), Scherr, C. E. L. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Smith, M. E. (Co-Investigator), Smith, M. E. (Co-Investigator), Starren, J. (Co-Investigator), Starren, J. (Co-Investigator), Walunas, T. L. (Co-Investigator), Walunas, T. L. (Co-Investigator), Wehbe, F. (Co-Investigator), Wehbe, F. (Co-Investigator), Aufox, S. A. (Other), Aufox, S. A. (Other), Hoell, C. (Other) & Hoell, C. (Other)
National Human Genome Research Institute
7/1/20 → 4/30/25
Project: Research project
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Pharmacogenomics Global Research Network Collaboration Grant
Perera, M. (PD/PI)
Pharmacogenomics Global Research Network Inc.
4/1/23 → 3/31/24
Project: Research project
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Use of a Machine Learning Approach to Impute Gene Expression in African Americans
Perera, M. (PD/PI)
National Human Genome Research Institute
6/10/21 → 5/31/24
Project: Research project
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Uncovering New Patterns Fellowship in Cardiovascular Disease and Stroke: Effect of genomic regulation on Clopidogrel Response in African Americans
Perera, M. (PD/PI)
4/2/18 → 4/1/20
Project: Research project
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LA-GEM: Imputation of gene expression with incorporation of Local Ancestry
Mishra, M., Nahlawi, L., Zhong, Y., De, T., Yang, G., Alarcon, C. & Perera, M. A., 2024, Pacific Symposium on Biocomputing 2024, PSB 2024. Altman, R. B., Hunter, L., Ritchie, M. D., Murray, T. & Klein, T. E. (eds.). 2024 ed. World Scientific, p. 341-358 18 p.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Open Access1 Scopus citations -
Genomewide Association Study Identifies Copy Number Variants Associated With Warfarin Dose Response and Risk of Venous Thromboembolism in African Americans
Zhang, H., Alarcon, C., Cavallari, L. H., Nutescu, E., Carvill, G. L., Perera, M. A. & Hernandez, W., Mar 2023, In: Clinical pharmacology and therapeutics. 113, 3, p. 624-633 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Implementation of pharmacogenomics into inpatient general medicine
Chen, T., O'Donnell, P. H., Middlestadt, M., Ruhnke, G. W., Danahey, K., Van Wijk, X. M. R., Choksi, A., Knoebel, R., Hartman, S., Yeo, K. T. J., Friedman, P. N., Ratain, M. J., Nutescu, E. A., O'Leary, K. J., Perera, M. A. & Meltzer, D. O., Feb 1 2023, In: Pharmacogenetics and genomics. 33, 2, p. 19-23 5 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Leveraging drug perturbation to reveal genetic regulators of hepatic gene expression in African Americans
Zhong, Y., De, T., Mishra, M., Avitia, J., Alarcon, C. & Perera, M. A., Jan 5 2023, In: American journal of human genetics. 110, 1, p. 58-70 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Local Ancestry-Informed Candidate Pathway Analysis of Warfarin Stable Dose in Latino Populations
Steiner, H. E., Carrion, K. C., Giles, J. B., Lima, A. R., Yee, K., Sun, X., Cavallari, L. H., Perera, M. A., Duconge, J. & Karnes, J. H., Mar 2023, In: Clinical pharmacology and therapeutics. 113, 3, p. 680-691 12 p.Research output: Contribution to journal › Article › peer-review
Open Access