Grants per year
Personal profile
Research Interests
The Perera laboratory focuses on pharmacogenomics (using a patient's genome to predict drug response) in minority populations. Working in this translation research space requires both clinical expertise as well as the use of high-throughput basic science approaches. Our goal is to bring the benefits of precision medicine to all US populations.
Training Experience
| 2006 | Postdoctoral Fellowship, University of Chicago |
Education/Academic qualification
PhD, Ohio State University
… → 2003
PharmD, University of Tennessee
… → 2001
Keywords
- Adverse Drug Reactions
- Autoimmune Diseases
- Gene Regulation
- Genomic Medicine/Personalized Medicine
- Inflammatory Bowel Disease
- Pharmacogenomics
- Pharmacology
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 2 Similar Profiles
Warfarin
Medicine & Life Sciences
Pharmacogenetics
Medicine & Life Sciences
African Americans
Medicine & Life Sciences
Single Nucleotide Polymorphism
Medicine & Life Sciences
Population
Medicine & Life Sciences
Genome-Wide Association Study
Medicine & Life Sciences
Genotype
Medicine & Life Sciences
Precision Medicine
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2016 2021
- 8 Active
Uncovering New Patterns Fellowship in Cardiovascular Disease and Stroke: Effect of genomic regulation on Clopidogrel Response in African Americans
4/2/18 → 4/1/20
Project: Research project
clopidogrel
African Americans
Cardiovascular Diseases
Myocardial Infarction
Single Nucleotide Polymorphism
Health disparity in pharmacogenomics: African American SNPs and drug metabolism
National Institute on Minority Health and Health Disparities
1/13/17 → 4/30/20
Project: Research project
Pharmacogenetics
African Americans
Single Nucleotide Polymorphism
Health
Pharmaceutical Preparations
Core: Analysis for "African American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translation" study
National Institute on Minority Health and Health Disparities
8/19/16 → 5/31/21
Project: Research project
Pharmacogenetics
African Americans
Precision Medicine
clopidogrel
Medicine
Project 1: African American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translation
Kho, A. N., O'Leary, K. J., Perera, M., Rasmussen-Torvik, L. J. & Smith, M. E.
National Institute on Minority Health and Health Disparities
8/19/16 → 5/31/21
Project: Research project
Pharmacogenetics
African Americans
Precision Medicine
clopidogrel
Medicine
African American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translation
National Institute on Minority Health and Health Disparities
8/19/16 → 5/31/21
Project: Research project
Pharmacogenetics
African Americans
Precision Medicine
clopidogrel
Medicine
Research Output 1998 2019
Cardiovascular Pharmacogenomics: Does It Matter if You're Black or White?
De, T., Sehwan Park, C. & Perera, M., Jan 6 2019, In : Annual Review of Pharmacology and Toxicology. 59, p. 577-603 27 p.Research output: Contribution to journal › Review article
Pharmacogenetics
Pharmaceutical Preparations
Population
Medical Genetics
Polymorphism
Differences in Warfarin Pharmacodynamics and Predictors of Response Among Three Racial Populations
Ohara, M., Suzuki, Y., Shinohara, S., Gong, I. Y., Schmerk, C. L., Tirona, R. G., Schwarz, U. I., Wen, M. S., Lee, M. T. M., Mihara, K., Nutescu, E. A., Perera, M., Cavallari, L. H., Kim, R. B. & Takahashi, H., Aug 1 2019, In : Clinical Pharmacokinetics. 58, 8, p. 1077-1089 13 p.Research output: Contribution to journal › Article
Warfarin
International Normalized Ratio
African Americans
Population
Pharmacokinetics
Leaving some behind: the growing gap in precision medicine for minority populations
Perera, M., Jan 2 2019, In : Expert Review of Precision Medicine and Drug Development. 4, 1, p. 3-5 3 p.Research output: Contribution to journal › Editorial
Precision Medicine
Population
On Using Local Ancestry to Characterize the Genetic Architecture of Human Traits: Genetic Regulation of Gene Expression in Multiethnic or Admixed Populations
Zhong, Y., Perera, M. & Gamazon, E. R., Jun 6 2019, In : American Journal of Human Genetics. 104, 6, p. 1097-1115 19 p.Research output: Contribution to journal › Article
Quantitative Trait Loci
Medical Genetics
Gene Expression Regulation
National Institute of General Medical Sciences (U.S.)
Population
The ACCOuNT Consortium: A Model for the Discovery, Translation, and Implementation of Precision Medicine in African Americans
Friedman, P. N., Shaazuddin, M., Gong, L., Grossman, R. L., Harralson, A. F., Klein, T. E., Lee, N. H., Miller, D. C., Nutescu, E. A., O'Brien, T. J., O'Donnell, P. H., O'Leary, K. J., Tuck, M., Meltzer, D. O. & Perera, M., May 1 2019, In : Clinical and Translational Science. 12, 3, p. 209-217 9 p.Research output: Contribution to journal › Review article
Open Access
Precision Medicine
Pharmacogenetics
African Americans
Medicine
Biomarkers