Grants per year
Personal profile
Research Interests
The Perera laboratory focuses on pharmacogenomics (using a patient's genome to predict drug response) in minority populations. Working in this translation research space requires both clinical expertise as well as the use of high-throughput basic science approaches. Our goal is to bring the benefits of precision medicine to all US populations.
Training Experience
| 2006 | Postdoctoral Fellowship, University of Chicago |
Education/Academic qualification
PhD, Ohio State University
… → 2003
PharmD, University of Tennessee
… → 2001
Research interests
- Adverse Drug Reactions
- Autoimmune Diseases
- Gene Regulation
- Genomic Medicine/Personalized Medicine
- Inflammatory Bowel Disease
- Pharmacogenomics
- Pharmacology
Fingerprint Dive into the research topics where Minoli Perera is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Warfarin
Medicine & Life Sciences
Pharmacogenetics
Medicine & Life Sciences
African Americans
Medicine & Life Sciences
Single Nucleotide Polymorphism
Medicine & Life Sciences
Population
Medicine & Life Sciences
Genome-Wide Association Study
Medicine & Life Sciences
Genotype
Medicine & Life Sciences
Genome
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2016 2021
- 8 Active
Uncovering New Patterns Fellowship in Cardiovascular Disease and Stroke: Effect of genomic regulation on Clopidogrel Response in African Americans
4/2/18 → 4/1/20
Project: Research project
clopidogrel
African Americans
Cardiovascular Diseases
Myocardial Infarction
Single Nucleotide Polymorphism
Health disparity in pharmacogenomics: African American SNPs and drug metabolism
National Institute on Minority Health and Health Disparities
1/13/17 → 4/30/20
Project: Research project
Pharmacogenetics
African Americans
Single Nucleotide Polymorphism
Health
Pharmaceutical Preparations
Core: Analysis for "African American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translation" study
National Institute on Minority Health and Health Disparities
8/19/16 → 5/31/21
Project: Research project
Pharmacogenetics
African Americans
Precision Medicine
clopidogrel
Medicine
Core: Implementation for "African American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translation" study
National Institute on Minority Health and Health Disparities
8/19/16 → 5/31/21
Project: Research project
Pharmacogenetics
African Americans
Precision Medicine
clopidogrel
Medicine
Project 2: African American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translation
Kho, A. N., O'Leary, K. J., Perera, M., Rasmussen-Torvik, L. J. & Smith, M. E.
National Institute on Minority Health and Health Disparities
8/19/16 → 5/31/21
Project: Research project
Pharmacogenetics
African Americans
Precision Medicine
clopidogrel
Medicine
Research Output 1998 2020
Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation
Hernandez, W., Danahey, K., Pei, X., Yeo, K. T. J., Leung, E., Volchenboum, S. L., Ratain, M. J., Meltzer, D. O., Stranger, B. E., Perera, M. A. & O’Donnell, P. H., Feb 1 2020, In : Pharmacogenomics Journal. 20, 1, p. 126-135 10 p.Research output: Contribution to journal › Article
Metagenomics
Pharmacogenetics
Genotype
Clinical Decision Support Systems
African Americans
A review of African Americans' beliefs and attitudes about genomic studies: Opportunities for message design
Scherr, C. L., Ramesh, S., Marshall-Fricker, C. & Perera, M. A., Jan 1 2019, In : Frontiers in Genetics. 10, JUN, 548.Research output: Contribution to journal › Review article
Open Access
Epoprostenol
African Americans
Precision Medicine
Population
Pharmacogenetics
2
Citations
(Scopus)
Cardiovascular Pharmacogenomics: Does It Matter if You're Black or White?
De, T., Sehwan Park, C. & Perera, M. A., Jan 6 2019, In : Annual Review of Pharmacology and Toxicology. 59, p. 577-603 27 p.Research output: Contribution to journal › Review article
Pharmacogenetics
Pharmaceutical Preparations
Population
Medical Genetics
Polymorphism
1
Citation
(Scopus)
Differences in Warfarin Pharmacodynamics and Predictors of Response Among Three Racial Populations
Ohara, M., Suzuki, Y., Shinohara, S., Gong, I. Y., Schmerk, C. L., Tirona, R. G., Schwarz, U. I., Wen, M. S., Lee, M. T. M., Mihara, K., Nutescu, E. A., Perera, M., Cavallari, L. H., Kim, R. B. & Takahashi, H., Aug 1 2019, In : Clinical Pharmacokinetics. 58, 8, p. 1077-1089 13 p.Research output: Contribution to journal › Article
Warfarin
International Normalized Ratio
African Americans
Population
Pharmacokinetics
Hepatocyte gene expression and DNA methylation as ancestry-dependent mechanisms in African Americans
Park, C. S., De, T., Xu, Y., Zhong, Y., Smithberger, E., Alarcon, C., Gamazon, E. R. & Perera, M. A., Dec 1 2019, In : npj Genomic Medicine. 4, 1, 29.Research output: Contribution to journal › Article
Open Access
DNA Methylation
African Americans
Hepatocytes
Gene Expression
Pharmaceutical Preparations