Grants per year
Personal profile
Research Interests
The Perera laboratory focuses on pharmacogenomics (using a patient's genome to predict drug response) in minority populations. Working in this translation research space requires both clinical expertise as well as the use of high-throughput basic science approaches. Our goal is to bring the benefits of precision medicine to all US populations.
Training Experience
2006 | Postdoctoral Fellowship, University of Chicago |
Education/Academic qualification
PhD, Pharmaceutics, Ohio State University
… → 2003
Pharmacology, PharmD, University of Tennessee
… → 2001
Research interests
- Adverse Drug Reactions
- Autoimmune Diseases
- Gene Regulation
- Genomic Medicine/Personalized Medicine
- Inflammatory Bowel Disease
- Pharmacogenomics
- Pharmacology
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Use of a Machine Learning Approach to Impute Gene Expression in African Americans
National Human Genome Research Institute
6/10/21 → 5/31/23
Project: Research project
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Northwestern Genomic Risk Assessment and Management Program
Chisholm, R. L., McNally, E. M., Rasmussen-Torvik, L. J., Gordon, A. S., Kho, A. N., Luo, Y., Perera, M., Roy-Puckelwartz, M. J., Scherr, C. E. L., Scholtens, D. M., Smith, M. E., Starren, J. B., Walunas, T. L., Wehbe, F., Aufox, S. A. & Hoell, C.
National Human Genome Research Institute
7/1/20 → 4/30/25
Project: Research project
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Genetic association of primary nonresponse to anti-TNFα therapy in patients with inflammatory bowel disease
De, T., Zhang, H., Alarcon, C., Lec, B., Avitia, J., Smithberger, E., Chen, C., Horvath, M., Kwan, S., Young, M., Adhikari, S., Kwon, J., Pacheco, J., Jarvik, G., Wei, W. Q., Mentch, F., Hakonarson, H., Sleiman, P., Gordon, A., Harley, J., & 4 others , Jan 1 2022, In: Pharmacogenetics and genomics. 32, 1, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Warfarin Dosing in Patients With CYP2C9*5 Variant Alleles
Lindley, K. J., Limdi, N. A., Cavallari, L. H., Perera, M. A., Lenzini, P., Johnson, J. A., Wu, A. H. B., Ridker, P. M., King, C. R., Eby, C. S., Patel, S., Shah, S. V., Beasley, T. M., Li, J. & Gage, B. F., Apr 2022, In: Clinical pharmacology and therapeutics. 111, 4, p. 950-955 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Applicability of pharmacogenomically guided medication treatment during hospitalization of at-risk minority patients
Saulsberry, L., Danahey, K., Middlestadt, M., O’leary, K. J., Nutescu, E. A., Chen, T., Lee, J. C., Ruhnke, G. W., George, D., House, L., van Wijk, X. M. R., Yeo, K. T. J., Choksi, A., Hartman, S. W., Knoebel, R. W., Friedman, P. N., Rasmussen, L. V., Ratain, M. J., Perera, M. A., Meltzer, D. O., & 1 others , Dec 2021, In: Journal of Personalized Medicine. 11, 12, 1343.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Differences in the Platelet mRNA Landscape Portend Racial Disparities in Platelet Function and Suggest Novel Therapeutic Targets
Garofano, K., Park, C. S., Alarcon, C., Avitia, J., Barbour, A., Diemert, D., Fraser, C. M., Friedman, P. N., Horvath, A., Rashid, K., Shaazuddin, M., Sidahmed, A., O’Brien, T. J., Perera, M. A. & Lee, N. H., Sep 2021, In: Clinical pharmacology and therapeutics. 110, 3, p. 702-713 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Incorporation of DNA methylation into eQTL mapping in African Americans
Singh, A., Zhong, Y., Nahlawi, L., Park, C. S., De, T., Alarcon, C. & Perera, M. A., 2021, In: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 26, p. 244-255 12 p.Research output: Contribution to journal › Article › peer-review