My research focuses on identifying effective therapeutic interventions for muscle, vasculature, peripheral nerve, and the brain, using adult stem cells and/or their secreted stimulator and protective factors to prevent, ameliorate, or reverse neurodegeneration associated with human disease, injury, and aging. Our experimental approaches include in vitro manipulation of adult stem cells and their therapeutic transplantation into clinically relevant animal models, immunohistochemistry labelling of cells and tissues to better understand mechanisms of functional improvement, and novel methods of whole animal in vivo imaging to track transplanted cell migration and engraftment. Our long term goal is to translate the knowledge from our findings to better assist patients with neuromuscular diseases, injuries, and aging-related pathologies.