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Mohammad Rizwan Siddiqui

  • 1633 Citations
20022019

Research output per year

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Personal profile

Research Interests

My research goal is to understand the regulation of lung inflammatory processes, particularly those involved in development of Acute Lung Injury (ALI). The major mechanisms of ALI includes breakdown of epithelial and endothelial fluid barriers, causing fluid accumulation in lung’s alveolar space. By using sepsis and infection induced ALI model, I am studying signaling mechanisms regulate barrier properties of endothelial cells and lung vascular injury. I aim to translate my basic research on lung disease for development of novel therapies for critically ill patients with ALI.

Education/Academic qualification

PhD, Jamia Millia Islamia

… → 2006

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Research Output

  • 1633 Citations
  • 20 Article
  • 1 Chapter
  • 1 Review article

MiR-144–mediated Inhibition of ROCK1 Protects against LPS-induced Lung Endothelial Hyperpermeability

Siddiqui, M. R., Akhtar, S., Shahid, M., Tauseef, M., McDonough, K. & Shanley, T. P., Aug 1 2019, In : American journal of respiratory cell and molecular biology. 61, 2, p. 257-265 9 p.

Research output: Contribution to journal › Article

    • 5 Scopus citations

    Emerging Potential of Immediate Early Response Gene X-1 in Cardiovascular and Metabolic Diseases

    Shahid, M., Hermes, E. L., Chandra, D., Tauseef, M., Siddiqui, M. R., Faridi, M. H. & Wu, M. X., Nov 6 2018, In : Journal of the American Heart Association. 7, 21, p. e009261

    Research output: Contribution to journal › Article

    Erythropoietin-mediated activation of aquaporin-4 channel for the treatment of experimental hydrocephalus

    Rizwan Siddiqui, M., Attar, F., Mohanty, V., Kim, K. S., Shekhar Mayanil, C. & Tomita, T., Nov 1 2018, In : Child's Nervous System. 34, 11, p. 2195-2202 8 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Folate Receptor Alpha Upregulates Oct4, Sox2 and Klf4 and Downregulates miR-138 and miR-let-7 in Cranial Neural Crest Cells

    Mohanty, V., Shah, A., Allender, E., Siddiqui, M. R., Monick, S., Ichi, S., Mania-Farnell, B., McLone, D. G., Tomita, T. & Mayanil, C. S., Nov 1 2016, In : Stem Cells. 34, 11, p. 2721-2732 12 p.

    Research output: Contribution to journal › Article

    • 11 Scopus citations

    Angiopoietin-1 regulates brain endothelial permeability through PTPN-2 mediated tyrosine dephosphorylation of occludin

    Siddiqui, M. R., Mayanil, C. S., Kim, K. S. & Tomita, T., Jun 19 2015, In : PloS one. 10, 6, e0130857.

    Research output: Contribution to journal › Article

    • 16 Scopus citations