Mohammed Javeed I Ansari

  • 2060 Citations
20032019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2003 2019

Filter
Article
2019
2 Citations (Scopus)

Mechanistic analyses in kidney transplant recipients prospectively randomized to two steroid free regimen-Low dose Tacrolimus with Everolimus versus standard dose Tacrolimus with Mycophenolate Mofetil

Traitanon, O., Mathew, J., Shetty, A. A., Bontha, S. V., Maluf, D. G., El Kassis, Y., Park, S. H., Han, J., Ansari, M. J. I., Leventhal, J. R., Mas, V. & Gallon, L., May 1 2019, In : PloS one. 14, 5, e0216300.

Research output: Contribution to journalArticle

Open Access
tacrolimus
Mycophenolic Acid
kidney transplant
Transplants
Tacrolimus
2018
28 Citations (Scopus)

A Phase i Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants

Mathew, J. M., H-Voss, J., LeFever, A., Konieczna, I., Stratton, C., He, J., Huang, X., Gallon, L., Skaro, A., Ansari, M. J. & Leventhal, J. R., Dec 1 2018, In : Scientific reports. 8, 1, 7428.

Research output: Contribution to journalArticle

Living Donors
Regulatory T-Lymphocytes
Clinical Trials
Transplants
Kidney
2015
23 Citations (Scopus)

Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimus

Gallon, L., Traitanon, O., Sustento-Reodica, N., Leventhal, J., Ansari, M. J., Gehrau, R. C., Ariyamuthu, V., De Serres, S. A., Alvarado, A., Chhabra, D., Mathew, J. M., Najafian, N. & Mas, V., Apr 8 2015, In : Kidney international. 87, 4, p. 828-838 11 p.

Research output: Contribution to journalArticle

Tacrolimus
Sirolimus
Kidney
Transplants
T-Lymphocytes
2014
21 Citations (Scopus)

Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection

Sarraj, B., Ye, J., Akl, A. I., Chen, G., Wang, J. J., Zhang, Z. J., Abadja, F., Abecassis, M. M., Miller, S. D., Kansas, G. S. & Ansari, M. J. I., Aug 19 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 33, p. 12145-12150 6 p.

Research output: Contribution to journalArticle

Selectins
Allografts
Leukocytes
T-Lymphocytes
Graft Survival
2013
15 Citations (Scopus)

CD160Ig Fusion Protein Targets a Novel Costimulatory Pathway and Prolongs Allograft Survival

D'Addio, F., Ueno, T., Clarkson, M., Zhu, B., Vergani, A., Freeman, G. J., Sayegh, M. H., Ansari, M. J. I., Fiorina, P. & Habicht, A., Apr 4 2013, In : PloS one. 8, 4, e60391.

Research output: Contribution to journalArticle

allografting
T-cells
Allografts
Fusion reactions
T-lymphocytes
10 Citations (Scopus)

Prolonged, Low-Dose Anti-Thymocyte Globulin, Combined with CTLA4-Ig, Promotes Engraftment in a Stringent Transplant Model

D'Addio, F., Boenisch, O., Magee, C. N., Yeung, M. Y., Yuan, X., Mfarrej, B., Vergani, A., Ansari, M. J. I., Fiorina, P. & Najafian, N., Jan 17 2013, In : PloS one. 8, 1, e53797.

Research output: Contribution to journalArticle

Transplants
Antilymphocyte Serum
thymocytes
globulins
Globulins
2012
111 Citations (Scopus)

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

Blatner, N. R., Mulcahy, M. F., Dennis, K. L., Scholtens, D., Bentrem, D. J., Phillips, J. D., Ham, S., Sandall, B. P., Khan, M. W., Mahvi, D. M., Halverson, A. L., Stryker, S. J., Boller, A. M., Singal, A., Sneed, R. K., Sarraj, B., Ansari, M. J., Oft, M., Iwakura, Y., Zhou, L. & 4 others, Bonertz, A., Beckhove, P., Gounari, F. & Khazaie, K., Dec 12 2012, In : Science translational medicine. 4, 164

Research output: Contribution to journalArticle

T-Lymphocyte Subsets
Regulatory T-Lymphocytes
Polyps
Colonic Neoplasms
Interleukin-17
2011
161 Citations (Scopus)

Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid

Mohamadzadeh, M., Pfeiler, E. A., Brown, J. B., Zadeh, M., Gramarossa, M., Managlia, E., Bere, P., Sarraj, B., Khan, M. W., Pakanati, K. C., Ansari, M. J., O'Flaherty, S., Barrett, T. & Klaenhammer, T. R., Mar 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, SUPPL. 1, p. 4623-4630 8 p.

Research output: Contribution to journalArticle

Lactobacillus acidophilus
Colitis
Dendritic Cells
Dextran Sulfate
Interleukin-12
2010
34 Citations (Scopus)

A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model

D'Addio, F., Yuan, X., Habicht, A., Williams, J., Ruzek, M., Iacomini, J., Turka, L. A., Sayegh, M. H., Najafian, N. & Ansari, M. J. I., Aug 15 2010, In : Transplantation. 90, 3, p. 260-269 10 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
T-Lymphocytes
Transplants
Sirolimus
Organ Transplantation
56 Citations (Scopus)

A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice

Vergani, A., D'Addio, F., Jurewicz, M., Petrelli, A., Watanabe, T., Liu, K., Law, K., Schuetz, C., Carvello, M., Orsenigo, E., Deng, S., Rodig, S. J., Ansari, J. M., Staudacher, C., Abdi, R., Williams, J., Markmann, J., Atkinson, M., Sayegh, M. H. & Fiorina, P., Sep 2010, In : Diabetes. 59, 9, p. 2253-2264 12 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Autoimmunity
Islets of Langerhans Transplantation
Obese Mice
Type 1 Diabetes Mellitus
2009
53 Citations (Scopus)

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

Yuan, X., Ansari, M. J. I., D'Addio, F., Paez-Cortez, J., Schmitt, I., Donnarumma, M., Boenisch, O., Zhao, X., Popoola, J., Clarkson, M. R., Yagita, H., Akiba, H., Freeman, G. J., Iacomini, J., Turka, L. A., Glimcher, L. H. & Sayegh, M. H., Jun 30 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 26, p. 10734-10739 6 p.

Research output: Contribution to journalArticle

Transplantation Tolerance
Interleukin-17
T-Lymphocytes
Mucin-1
Allografts
2008
225 Citations (Scopus)

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

Yuan, X., Paez-Cortez, J., Schmitt-Knosalla, I., D'Addio, F., Mfarrej, B., Donnarumma, M., Habicht, A., Clarkson, M. R., Iacomini, J., Glimcher, L. H., Sayegh, M. H. & Javeed Ansari, M., Dec 22 2008, In : Journal of Experimental Medicine. 205, 13, p. 3133-3144 12 p.

Research output: Contribution to journalArticle

Th17 Cells
Allografts
Interleukin-17
Cytokines
T-Lymphocytes
61 Citations (Scopus)

Critical role of donor tissue expression of programmed death ligand-1 in regulating cardiac allograft rejection and vasculopathy

Yang, J., Popoola, J., Khandwala, S., Vadivel, N., Vanguri, V., Yuan, X., Dada, S., Guleria, I., Tian, C., Ansari, M. J., Shin, T., Yagita, H., Azuma, M., Sayegh, M. H. & Chandraker, A., Feb 5 2008, In : Circulation. 117, 5, p. 660-669 10 p.

Research output: Contribution to journalArticle

Allografts
Tissue Donors
Ligands
T-Lymphocytes
Graft Survival
70 Citations (Scopus)

Mechanisms underlying blockade of allograft acceptance by TLR ligands

Porrett, P. M., Yuan, X., LaRosa, D. F., Walsh, P. T., Yang, J., Gao, W., Li, P., Zhang, J., Ansari, J. M., Hancock, W. W., Sayegh, M. H., Koulmanda, M., Strom, T. B. & Turka, L. A., Aug 1 2008, In : Journal of Immunology. 181, 3, p. 1692-1699 8 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Allografts
Ligands
Transplants
Interleukin-6
45 Citations (Scopus)

Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice

Ansari, M. J. I., Fiorina, P., Dada, S., Guleria, I., Ueno, T., Yuan, X., Trikudanathan, S., Smith, R. N., Freeman, G. & Sayegh, M. H., Feb 1 2008, In : Clinical Immunology. 126, 2, p. 140-147 8 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Autoimmunity
Allografts
Islets of Langerhans Transplantation
Graft Survival
82 Citations (Scopus)

The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model

Ueno, T., Habicht, A., Clarkson, M. R., Albin, M. J., Yamaura, K., Boenisch, O., Popoola, J., Wang, Y., Yagita, H., Akiba, H., Ansari, M. J., Yang, J., Turka, L. A., Rothstein, D. M., Padera, R. F., Najafian, N. & Sayegh, M. H., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 742-751 10 p.

Research output: Contribution to journalArticle

Mucin-1
T-Lymphocytes
Transplants
Allografts
Antibodies
2007
21 Citations (Scopus)

Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy

Tian, C., Ansari, M. J. I., Paez-Cortez, J., Bagley, J., Godwin, J., Donnarumma, M., Sayegh, M. H. & Iacomini, J., Nov 15 2007, In : Journal of Immunology. 179, 10, p. 6762-6769 8 p.

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
Type 1 Diabetes Mellitus
Genetic Therapy
Inbred NOD Mouse
Viruses
77 Citations (Scopus)

Mechanisms of PDL1-mediated regulation of autoimmune diabetes

Guleria, I., Gubbels Bupp, M., Dada, S., Fife, B., Tang, Q., Ansari, M. J., Trikudanathan, S., Vadivel, N., Fiorina, P., Yagita, H., Azuma, M., Atkinson, M., Bluestone, J. A. & Sayegh, M. H., Oct 1 2007, In : Clinical Immunology. 125, 1, p. 16-25 10 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
T-Lymphocytes
Inbred NOD Mouse
Transgenic Mice
Lymph Nodes
2006
18 Citations (Scopus)

Costimulation and autoimmune diabetes in BB rats

Beaudette-Zlatanova, B. C., Whalen, B., Zipris, D., Yagita, H., Rozing, J., Groen, H., Benjamin, C. D., Hunig, T., Drexhage, H. A., Ansari, M. J., Leif, J., Mordes, J. P., Greiner, D. L., Sayegh, M. H. & Rossini, A. A., May 1 2006, In : American Journal of Transplantation. 6, 5 I, p. 894-902 9 p.

Research output: Contribution to journalArticle

Inbred BB Rats
Type 1 Diabetes Mellitus
Monoclonal Antibodies
Poly I-C
Regulatory T-Lymphocytes
57 Citations (Scopus)

Role of CXC chemokine receptor 3 pathway in renal ischemic injury

Fiorina, P., Ansari, M. J., Jurewicz, M., Barry, M., Ricchiuti, V., Smith, R. N., Shea, S., Means, T. K., Auchincloss, H., Luster, A. D., Sayegh, M. H. & Abdi, R., Mar 1 2006, In : Journal of the American Society of Nephrology. 17, 3, p. 716-723 8 p.

Research output: Contribution to journalArticle

CXCR3 Receptors
Reperfusion Injury
Kidney
Wounds and Injuries
Ischemia
2005
256 Citations (Scopus)

A critical role for the programmed death ligand 1 in fetomaternal tolerance

Guleria, I., Khosroshahi, A., Ansari, M. J., Habicht, A., Azuma, M., Yagita, H., Noelle, R. J., Coyle, A., Mellor, A. L., Khoury, S. J. & Sayegh, M. H., Jul 18 2005, In : Journal of Experimental Medicine. 202, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

Ligands
Isoantigens
Pregnancy
B-Lymphocytes
T-Lymphocytes
2004
22 Citations (Scopus)

Clinical transplantation tolerance: The promise and challenges

Ansari, M. J. I. & Sayegh, M. H., May 2004, In : Kidney international. 65, 5, p. 1560-1563 4 p.

Research output: Contribution to journalArticle

Transplantation Tolerance
Transplants
Drug Tolerance
Organ Transplantation
Immunosuppressive Agents
2003
29 Citations (Scopus)

Allorecognition and effector pathways of islet allograft rejection in normal versus nonobese diabetic mice

Makhlouf, L., Yamada, A., Ito, T., Abdi, R., Ansari, M. J. I., Khuong, C. Q., Winn, H. J., Auchincloss, H. & Sayegh, M. H., Aug 1 2003, In : Journal of the American Society of Nephrology. 14, 8, p. 2168-2175 8 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Allografts
T-Lymphocytes
Autoimmunity
Inbred C57BL Mouse
491 Citations (Scopus)

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

Ansari, M. J. I., Salama, A. D., Chitnis, T., Smith, R. N., Yagita, H., Akiba, H., Yamazaki, T., Azuma, M., Iwai, H., Khoury, S. J., Auchincloss, H. & Sayegh, M. H., Jul 7 2003, In : Journal of Experimental Medicine. 198, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
CTLA-4 Antigen
Peripheral Tolerance
Congenic Mice