Mohammed Javeed I Ansari

  • 2103 Citations
20032019

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Article

A critical role for the programmed death ligand 1 in fetomaternal tolerance

Guleria, I., Khosroshahi, A., Ansari, M. J., Habicht, A., Azuma, M., Yagita, H., Noelle, R. J., Coyle, A., Mellor, A. L., Khoury, S. J. & Sayegh, M. H., Jul 18 2005, In : Journal of Experimental Medicine. 202, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

267 Scopus citations

Allorecognition and effector pathways of islet allograft rejection in normal versus nonobese diabetic mice

Makhlouf, L., Yamada, A., Ito, T., Abdi, R., Ansari, M. J. I., Khuong, C. Q., Winn, H. J., Auchincloss, H. & Sayegh, M. H., Aug 1 2003, In : Journal of the American Society of Nephrology. 14, 8, p. 2168-2175 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model

D'Addio, F., Yuan, X., Habicht, A., Williams, J., Ruzek, M., Iacomini, J., Turka, L. A., Sayegh, M. H., Najafian, N. & Ansari, M. J. I., Aug 15 2010, In : Transplantation. 90, 3, p. 260-269 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice

Vergani, A., D'Addio, F., Jurewicz, M., Petrelli, A., Watanabe, T., Liu, K., Law, K., Schuetz, C., Carvello, M., Orsenigo, E., Deng, S., Rodig, S. J., Ansari, J. M., Staudacher, C., Abdi, R., Williams, J., Markmann, J., Atkinson, M., Sayegh, M. H. & Fiorina, P., Sep 2010, In : Diabetes. 59, 9, p. 2253-2264 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

Yuan, X., Paez-Cortez, J., Schmitt-Knosalla, I., D'Addio, F., Mfarrej, B., Donnarumma, M., Habicht, A., Clarkson, M. R., Iacomini, J., Glimcher, L. H., Sayegh, M. H. & Javeed Ansari, M., Dec 22 2008, In : Journal of Experimental Medicine. 205, 13, p. 3133-3144 12 p.

Research output: Contribution to journalArticle

227 Scopus citations

A Phase i Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants

Mathew, J. M., H-Voss, J., LeFever, A., Konieczna, I., Stratton, C., He, J., Huang, X., Gallon, L., Skaro, A., Ansari, M. J. & Leventhal, J. R., Dec 1 2018, In : Scientific reports. 8, 1, 7428.

Research output: Contribution to journalArticle

34 Scopus citations

CD160Ig Fusion Protein Targets a Novel Costimulatory Pathway and Prolongs Allograft Survival

D'Addio, F., Ueno, T., Clarkson, M., Zhu, B., Vergani, A., Freeman, G. J., Sayegh, M. H., Ansari, M. J. I., Fiorina, P. & Habicht, A., Apr 4 2013, In : PloS one. 8, 4, e60391.

Research output: Contribution to journalArticle

15 Scopus citations

Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimus

Gallon, L., Traitanon, O., Sustento-Reodica, N., Leventhal, J., Ansari, M. J., Gehrau, R. C., Ariyamuthu, V., De Serres, S. A., Alvarado, A., Chhabra, D., Mathew, J. M., Najafian, N. & Mas, V., Apr 8 2015, In : Kidney international. 87, 4, p. 828-838 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Clinical transplantation tolerance: The promise and challenges

Ansari, M. J. I. & Sayegh, M. H., May 2004, In : Kidney international. 65, 5, p. 1560-1563 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

Costimulation and autoimmune diabetes in BB rats

Beaudette-Zlatanova, B. C., Whalen, B., Zipris, D., Yagita, H., Rozing, J., Groen, H., Benjamin, C. D., Hunig, T., Drexhage, H. A., Ansari, M. J., Leif, J., Mordes, J. P., Greiner, D. L., Sayegh, M. H. & Rossini, A. A., May 1 2006, In : American Journal of Transplantation. 6, 5 I, p. 894-902 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Critical role of donor tissue expression of programmed death ligand-1 in regulating cardiac allograft rejection and vasculopathy

Yang, J., Popoola, J., Khandwala, S., Vadivel, N., Vanguri, V., Yuan, X., Dada, S., Guleria, I., Tian, C., Ansari, M. J., Shin, T., Yagita, H., Azuma, M., Sayegh, M. H. & Chandraker, A., Feb 5 2008, In : Circulation. 117, 5, p. 660-669 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

Blatner, N. R., Mulcahy, M. F., Dennis, K. L., Scholtens, D., Bentrem, D. J., Phillips, J. D., Ham, S., Sandall, B. P., Khan, M. W., Mahvi, D. M., Halverson, A. L., Stryker, S. J., Boller, A. M., Singal, A., Sneed, R. K., Sarraj, B., Ansari, M. J., Oft, M., Iwakura, Y., Zhou, L. & 4 others, Bonertz, A., Beckhove, P., Gounari, F. & Khazaie, K., Dec 12 2012, In : Science translational medicine. 4, 164

Research output: Contribution to journalArticle

113 Scopus citations

Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection

Sarraj, B., Ye, J., Akl, A. I., Chen, G., Wang, J. J., Zhang, Z. J., Abadja, F., Abecassis, M. M., Miller, S. D., Kansas, G. S. & Ansari, M. J. I., Aug 19 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 33, p. 12145-12150 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy

Tian, C., Ansari, M. J. I., Paez-Cortez, J., Bagley, J., Godwin, J., Donnarumma, M., Sayegh, M. H. & Iacomini, J., Nov 15 2007, In : Journal of Immunology. 179, 10, p. 6762-6769 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mechanisms of PDL1-mediated regulation of autoimmune diabetes

Guleria, I., Gubbels Bupp, M., Dada, S., Fife, B., Tang, Q., Ansari, M. J., Trikudanathan, S., Vadivel, N., Fiorina, P., Yagita, H., Azuma, M., Atkinson, M., Bluestone, J. A. & Sayegh, M. H., Oct 1 2007, In : Clinical Immunology. 125, 1, p. 16-25 10 p.

Research output: Contribution to journalArticle

77 Scopus citations

Mechanisms underlying blockade of allograft acceptance by TLR ligands

Porrett, P. M., Yuan, X., LaRosa, D. F., Walsh, P. T., Yang, J., Gao, W., Li, P., Zhang, J., Ansari, J. M., Hancock, W. W., Sayegh, M. H., Koulmanda, M., Strom, T. B. & Turka, L. A., Aug 1 2008, In : Journal of Immunology. 181, 3, p. 1692-1699 8 p.

Research output: Contribution to journalArticle

71 Scopus citations

Mechanistic analyses in kidney transplant recipients prospectively randomized to two steroid free regimen-Low dose Tacrolimus with Everolimus versus standard dose Tacrolimus with Mycophenolate Mofetil

Traitanon, O., Mathew, J. M., Shetty, A., Bontha, S. V., Maluf, D. G., El Kassis, Y., Park, S. H., Han, J., Ansari, M. J., Leventhal, J. R., Mas, V. & Gallon, L., May 2019, In : PloS one. 14, 5, e0216300.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Prolonged, Low-Dose Anti-Thymocyte Globulin, Combined with CTLA4-Ig, Promotes Engraftment in a Stringent Transplant Model

D'Addio, F., Boenisch, O., Magee, C. N., Yeung, M. Y., Yuan, X., Mfarrej, B., Vergani, A., Ansari, M. J. I., Fiorina, P. & Najafian, N., Jan 17 2013, In : PloS one. 8, 1, e53797.

Research output: Contribution to journalArticle

10 Scopus citations

Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid

Mohamadzadeh, M., Pfeiler, E. A., Brown, J. B., Zadeh, M., Gramarossa, M., Managlia, E., Bere, P., Sarraj, B., Khan, M. W., Pakanati, K. C., Ansari, M. J., O'Flaherty, S., Barrett, T. & Klaenhammer, T. R., Mar 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, SUPPL. 1, p. 4623-4630 8 p.

Research output: Contribution to journalArticle

163 Scopus citations

Role of CXC chemokine receptor 3 pathway in renal ischemic injury

Fiorina, P., Ansari, M. J., Jurewicz, M., Barry, M., Ricchiuti, V., Smith, R. N., Shea, S., Means, T. K., Auchincloss, H., Luster, A. D., Sayegh, M. H. & Abdi, R., Mar 1 2006, In : Journal of the American Society of Nephrology. 17, 3, p. 716-723 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice

Ansari, M. J. I., Fiorina, P., Dada, S., Guleria, I., Ueno, T., Yuan, X., Trikudanathan, S., Smith, R. N., Freeman, G. & Sayegh, M. H., Feb 1 2008, In : Clinical Immunology. 126, 2, p. 140-147 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

Yuan, X., Ansari, M. J. I., D'Addio, F., Paez-Cortez, J., Schmitt, I., Donnarumma, M., Boenisch, O., Zhao, X., Popoola, J., Clarkson, M. R., Yagita, H., Akiba, H., Freeman, G. J., Iacomini, J., Turka, L. A., Glimcher, L. H. & Sayegh, M. H., Jun 30 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 26, p. 10734-10739 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model

Ueno, T., Habicht, A., Clarkson, M. R., Albin, M. J., Yamaura, K., Boenisch, O., Popoola, J., Wang, Y., Yagita, H., Akiba, H., Ansari, M. J., Yang, J., Turka, L. A., Rothstein, D. M., Padera, R. F., Najafian, N. & Sayegh, M. H., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 742-751 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

Ansari, M. J. I., Salama, A. D., Chitnis, T., Smith, R. N., Yagita, H., Akiba, H., Yamazaki, T., Azuma, M., Iwai, H., Khoury, S. J., Auchincloss, H. & Sayegh, M. H., Jul 7 2003, In : Journal of Experimental Medicine. 198, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

498 Scopus citations