Grants per year
Personal profile
Research Interests
Our research is focused on three main areas: 1. Microtubule regulators and their role in virus infection. 2. The role of the kinesin-1 adaptor protein, FEZ1 in HIV-1 infection. 3. Understanding HIV-1 Infection in the Brain and HIV-Induced Neurodegeneration. Please visit our lab webpage for the most up to date information on our ongoing research: http://labs.feinberg.northwestern.edu/naghavi/
Training Experience
2006 | Postdoctoral Fellowship, Columbia University |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Virology, PhD, Karolinska Institutet
… → 2001
Research interests keywords
- AIDS
- Cytoskeleton
- Infectious Diseases
- Viral Pathogenesis
- Virology
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Collaborations and top research areas from the last five years
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The interplay between HIV-1 and amyloid precursor protein in infection and neurotoxicity
Naghavi, M. (PD/PI), Naghavi, M. (PD/PI), Kiskinis, E. (Co-Investigator) & Kiskinis, E. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
4/1/23 → 3/31/28
Project: Research project
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+TIPs as novel host capsid-binding co-factors in early HIV-1 infection
Naghavi, M. (PD/PI) & Naghavi, M. (PD/PI)
National Institute of Allergy and Infectious Diseases
3/9/23 → 2/29/28
Project: Research project
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The role of FEZ1 in early HIV-1 infection
Naghavi, M. (PD/PI), Naghavi, M. (PD/PI) & Naghavi, M. (PD/PI)
National Institute of Allergy and Infectious Diseases
9/24/12 → 6/30/25
Project: Research project
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Supplement request for TIRF microscope for studies on the role of Microtubule regulators in HIV-1 infection
Naghavi, M. (PD/PI)
Columbia University, National Institute of General Medical Sciences
5/1/18 → 4/30/19
Project: Research project
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The role of amyloid precursor protein in HIV-1 replication and associated neurodegeneration
Naghavi, M. (PD/PI)
National Institute of Neurological Disorders and Stroke
2/1/17 → 1/31/23
Project: Research project
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The host cytoskeleton: a key regulator of early HIV-1 infection
Stephens, C. & Naghavi, M. H., May 2024, In: FEBS Journal. 291, 9, p. 1835-1848 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
FEZ1 Plays Dual Roles in Early HIV-1 Infection by Independently Regulating Capsid Transport and Host Interferon-Stimulated Gene Expression
Malikov, V. & Naghavi, M. H., Jun 29 2023, In: Journal of virology. 97, 6, p. e0049923Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
HIV-1 promotes ubiquitination of the amyloidogenic C-terminal fragment of APP to support viral replication
Gu, F., Boisjoli, M. & Naghavi, M. H., Dec 2023, In: Nature communications. 14, 1, 4227.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Microtubules and viral infection
da Silva, E. S. & Naghavi, M. H., Jan 2023, Advances in Virus Research. Kielian, M. & Roossinck, M. J. (eds.). Academic Press Inc, p. 87-134 48 p. (Advances in Virus Research; vol. 115).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Virology under the Microscope-a Call for Rational Discourse
Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A. & Brooke, C. & 136 others, , Jan 2023, In: mBio. 14, 1Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations
Datasets
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HIV-1 capsid hexamer R18D mutant
Huang, P.-T. (Contributor), Summers, B. J. (Contributor), Xu, C. (Contributor), Perilla, J. R. (Contributor), Malikov, V. (Contributor), Naghavi, M. H. (Contributor) & Xiong, Y. (Contributor), Protein Data Bank (PDB), Aug 21 2019
DOI: 10.2210/pdb6OMT/pdb, https://www.wwpdb.org/pdb?id=pdb_00006omt
Dataset