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Research Output 1995 2019

  • 920 Citations
  • 28 Article
  • 2 Comment/debate
  • 2 Review article
  • 1 Letter
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Article
2019
2 Citations (Scopus)

FEZ1 Is Recruited to a Conserved Cofactor Site on Capsid to Promote HIV-1 Trafficking

Huang, P. T., Summers, B. J., Xu, C., Perilla, J. R., Malikov, V., Naghavi, M. & Xiong, Y., Aug 27 2019, In : Cell reports. 28, 9, p. 2373-2385.e7

Research output: Contribution to journalArticle

Open Access
Kinesin
Capsid
HIV-1
Capsid Proteins
Phytic Acid
2018

"APP"reciating the complexity of HIV-induced neurodegenerative diseases

Naghavi, M., Oct 1 2018, In : PLoS pathogens. 14, 10, e1007309.

Research output: Contribution to journalArticle

Neurodegenerative Diseases
HIV
6 Citations (Scopus)

Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit

Meade, N., Furey, C., Li, H., Verma, R., Chai, Q., Rollins, M. G., DiGiuseppe, S., Naghavi, M. & Walsh, D., Aug 23 2018, In : Cell. 174, 5, p. 1143-1157.e17

Research output: Contribution to journalArticle

Poxviridae
Viruses
Antiviral Agents
Raptors
Poxviridae Infections
2017
9 Citations (Scopus)

Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport

Delaney, M. K., Malikov, V., Chai, Q., Zhao, G. & Naghavi, M., Aug 15 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 33, p. E6932-E6941

Research output: Contribution to journalArticle

Virus Uncoating
HIV-1
Microtubules
Capsid
Actins
8 Citations (Scopus)

HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration

Chai, Q., Jovasevic, V., Malikov, V., Sabo, Y., Morham, S., Walsh, D. & Naghavi, M., Dec 1 2017, In : Nature communications. 8, 1, 1522.

Research output: Contribution to journalArticle

human immunodeficiency virus
Amyloid beta-Protein Precursor
Viruses
HIV-1
constrictions
8 Citations (Scopus)

Localized Phosphorylation of a Kinesin-1 Adaptor by a Capsid-Associated Kinase Regulates HIV-1 Motility and Uncoating

Malikov, V. & Naghavi, M., Sep 19 2017, In : Cell reports. 20, 12, p. 2792-2799 8 p.

Research output: Contribution to journalArticle

Kinesin
Phosphorylation
Capsid
Fasciculation
HIV-1
12 Citations (Scopus)

Microtubule regulation and function during virus infection

Naghavi, M. & Walsh, D., Aug 1 2017, In : Journal of virology. 91, 16, e00538-17.

Research output: Contribution to journalArticle

Virus Diseases
Microtubules
microtubules
viruses
infection
2015
33 Citations (Scopus)

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus

Malikov, V., Da Silva, E. S., Jovasevic, V., Bennett, G., De Souza Aranha Vieira, D. A., Schulte, B., Diaz-Griffero, F., Walsh, D. & Naghavi, M., Jan 1 2015, In : Nature communications. 6, 6660.

Research output: Contribution to journalArticle

Peptide Elongation Factor 1
Peptide Elongation Factors
Kinesin
human immunodeficiency virus
Capsid
17 Citations (Scopus)
Human Herpesvirus 1
Microtubules
Virion
Dyneins
Herpesviridae
2014
1 Citation (Scopus)

Stable microtubule subsets facilitate early HIV-1 infection

Naghavi, M. H., Mar 1 2014, In : AIDS research and human retroviruses. 30, 3, p. 211-212 2 p.

Research output: Contribution to journalArticle

Host-Pathogen Interactions
Virus Internalization
Fluorescence Microscopy
Microtubules
HIV Infections
2013
64 Citations (Scopus)

HIV-1 induces the formation of stable microtubules to enhance early infection

Sabo, Y., Walsh, D., Barry, D. S., Tinaztepe, S., De Los Santos, K., Goff, S. P., Gundersen, G. G. & Naghavi, M. H., Nov 13 2013, In : Cell Host and Microbe. 14, 5, p. 535-546 12 p.

Research output: Contribution to journalArticle

Microtubules
HIV-1
Infection
Nocodazole
Carrier Proteins
22 Citations (Scopus)
Herpesviridae
Viral Proteins
Microtubules
Viruses
Proteins
2011
18 Citations (Scopus)

Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection

Brown, C., Morham, S. G., Walsh, D. & Naghavi, M. H., Jul 29 2011, In : Journal of Molecular Biology. 410, 5, p. 761-777 17 p.

Research output: Contribution to journalArticle

Talin
Paxillin
Vinculin
Focal Adhesions
Phosphorylation
16 Citations (Scopus)

PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1

Henning, M. S., Stiedl, P., Barry, D. S., McMahon, R., Morham, S. G., Walsh, D. & Naghavi, M. H., Jul 5 2011, In : Virology. 415, 2, p. 114-121 8 p.

Research output: Contribution to journalArticle

Cytoskeletal Proteins
Human Herpesvirus 1
Virus Diseases
Infection
Proteins
2010
21 Citations (Scopus)

PDZD8 is a novel gag-interacting factor that promotes retroviral infection

Henning, M. S., Morham, S. G., Goff, S. P. & Naghavi, M. H., Sep 1 2010, In : Journal of Virology. 84, 17, p. 8990-8995 6 p.

Research output: Contribution to journalArticle

HIV-1
Human immunodeficiency virus 1
Virus Diseases
Human Immunodeficiency Virus gag Gene Products
Infection
2009
16 Citations (Scopus)

The brain-specific factor FEZ1 is a determinant of neuronal susceptibility to HIV-1 infection

Haedicke, J., Brown, C. & Naghavi, M. H., Aug 18 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 33, p. 14040-14045 6 p.

Research output: Contribution to journalArticle

Fasciculation
Peptide Elongation Factors
HIV Infections
HIV-1
Neurons
2008
42 Citations (Scopus)

The Ezrin-Radixin-Moesin family member Ezrin regulates stable microtubule formation and retroviral infection

Haedicke, J., De Los Santos, K., Goff, S. P. & Naghavi, M. H., May 1 2008, In : Journal of virology. 82, 9, p. 4665-4670 6 p.

Research output: Contribution to journalArticle

reverse transcription
Human immunodeficiency virus 1
Microtubules
microtubules
Retroviridae
2007
71 Citations (Scopus)

Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells

Naghavi, M. H., Valente, S., Hatziioannou, T., De Los Santos, K., Wen, Y., Mott, C., Gundersen, G. G. & Goff, S. P., Jan 10 2007, In : EMBO Journal. 26, 1, p. 41-52 12 p.

Research output: Contribution to journalArticle

Microtubules
Cultured Cells
Cells
Viruses
Infection
2005
28 Citations (Scopus)

Overexpression of fasciculation and elongation protein ζ-1 (FEZ1) induces a post-entry block to retroviruses in cultured cells

Naghavi, M. H., Hatziioannou, T., Gao, G. & Goff, S. P., May 1 2005, In : Genes and Development. 19, 9, p. 1105-1115 11 p.

Research output: Contribution to journalArticle

Fasciculation
Retroviridae
Cultured Cells
Infection
Proteins
2004
14 Citations (Scopus)

T-cell activation leads to poor activation of the HIV-1 clade E long terminal repeat and weak association of nuclear factor-κB and NFAT with its enhancer region

Lemieux, A. M., Paré, M. È., Audet, B., Legault, É., Lefort, S., Boucher, N., Landry, S., Van Opijnen, T., Berkhout, B., Naghavi, M. H., Tremblay, M. J. & Barbeau, B., Dec 17 2004, In : Journal of Biological Chemistry. 279, 51, p. 52949-52960 12 p.

Research output: Contribution to journalArticle

T-cells
Terminal Repeat Sequences
Viruses
HIV-1
Chemical activation
2003
34 Citations (Scopus)

Intracellular high mobility group B1 protein (HMGB1) represses HIV-1 LTR-directed transcription in a promoter- and cell-specific manner

Naghavi, M. H., Nowak, P., Andersson, J., Sönnerborg, A., Yang, H., Tracey, K. J. & Vahlne, A., Sep 15 2003, In : Virology. 314, 1, p. 179-189 11 p.

Research output: Contribution to journalArticle

HIV Long Terminal Repeat
High Mobility Group Proteins
HIV-1
Terminal Repeat Sequences
HeLa Cells
2002
39 Citations (Scopus)

MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein

Estable, M. C., Naghavi, M. H., Kato, H., Xiao, H., Qin, J., Vahlne, A. & Roeder, R. G., Jun 26 2002, In : Journal of Biomedical Science. 9, 3, p. 234-245 12 p.

Research output: Contribution to journalArticle

Peptide Elongation Factors
Transcription
Leukemia
Cyclin T
Transcription Factors
2001
22 Citations (Scopus)

The nontoxic tripeptide glycyl-prolyl-glycine amide inhibits the replication of human immunodeficiency virus type 1

Su, J., Andersson, E., Horal, P., Naghavi, M. H., Palm, A., Wu, Y. P., Eriksson, K., Jansson, M., Wigzell, H., Svennerholm, B. & Vahlne, A., Feb 17 2001, In : Journal of Human Virology. 4, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

prolyl-glycyl-glycine
HIV-1
Ritonavir
Peptides
Zidovudine
13 Citations (Scopus)

The tripeptide glycyl-prolyl-glycine amide does not affect the early steps of the human immunodeficiency virus type 1 replication

Su, J., Naghavi, M. H., Jejcic, A., Horal, P., Furuta, Y., Wu, Y. P., Li, S. L., Hall, W. W., Goobar-Larsson, L., Svennerholm, B. & Vahlne, A., Feb 17 2001, In : Journal of Human Virology. 4, 1, p. 8-15 8 p.

Research output: Contribution to journalArticle

Virus Replication
HIV-1
prolyl-glycyl-glycine
Glycine
RNA Splicing
30 Citations (Scopus)
HIV Long Terminal Repeat
Terminal Repeat Sequences
HIV-1
Cell Line
Sequence Analysis
1999
24 Citations (Scopus)

DNA sequence of the long terminal repeat of human immunodeficiency virus type 1 subtype A through G

Naghavi, M. H., Salminen, M. O., Sönnerborg, A. & Vahlne, A., Mar 20 1999, In : AIDS Research and Human Retroviruses. 15, 5, p. 485-488 4 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
HIV Envelope Protein gp120
gag Genes
Terminal Repeat Sequences
Viral DNA
77 Citations (Scopus)

Long terminal repeat promoter/enhancer activity of different subtypes of HIV type 1

Naghavi, M. H., Schwartz, S., Sönnerborg, A. & Vahlne, A., Sep 20 1999, In : AIDS Research and Human Retroviruses. 15, 14, p. 1293-1303 11 p.

Research output: Contribution to journalArticle

Terminal Repeat Sequences
HIV-1
Viral Regulatory and Accessory Proteins
Transcription Factors
HIV Long Terminal Repeat
1995
203 Citations (Scopus)

Frequent patient-to-patient transmission of hepatitis C virus in a haematology ward

Allander, T., Gruber, A., Beyene, A., Björkholm, M., Persson, M. A. A., Allander, T., Naghavi, M., Söderstöm, T. & Grillner, L., Mar 11 1995, In : The Lancet. 345, 8950, p. 603-607 5 p.

Research output: Contribution to journalArticle

Hematology
Hepacivirus
Hepatitis C
Blood Donors
Hematologic Diseases