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Research Output

1993

A computerized grid walking system for evaluating the accuracy of locomotion in rats

Prakriya, M., McCabe, P. M. & Holets, V. R., Jun 1993, In : Journal of Neuroscience Methods. 48, 1-2, p. 15-25 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
1995

Inactivating and noninactivating Ca2+- and voltage-dependent K+ current in rat adrenal chromaffin cells

Solaro, C. R., Prakriya, M., Ding, J. P. & Lingle, C. J., Jan 1 1995, In : Journal of Neuroscience. 15, 9, p. 6110-6123 14 p.

Research output: Contribution to journalArticle

105 Scopus citations
1996

[Ca2+](i) elevations detected by BK channels during Ca2+ influx and muscarine-mediated release of Ca2+ from intracellular stores in rat chromaffin cells

Prakriya, M., Solaro, C. R. & Lingle, C. J., Jul 15 1996, In : Journal of Neuroscience. 16, 14, p. 4344-4359 16 p.

Research output: Contribution to journalArticle

50 Scopus citations

Ca2+-activated K+ channels in adrenal chromaffin cells

Lingle, CJ., Solaro, CR., Prakriya, M. & Ding, JP., 1996, Ion channels handbook. Narahashi, T. (ed.). New York: Plenum Press, p. 261-301

Research output: Chapter in Book/Report/Conference proceedingChapter

Calcium-activated potassium channels in adrenal chromaffin cells.

Lingle, C. J., Solaro, C. R., Prakriya, M. & Ding, J. P., 1996, In : Ion channels. 4, p. 261-301 41 p.

Research output: Contribution to journalReview article

63 Scopus citations
1998

Enantioselective blockade of T-type Ca2+ current in adult rat sensory neurons by a steroid that lacks γ-aminobutyric acid-modulatory activity

Todorovic, S. M., Prakriya, M., Nakashima, Y. M., Nilsson, K. R., Han, M., Zorumski, C. F., Covery, D. F. & Lingle, C. J., Nov 1998, In : Molecular Pharmacology. 54, 5, p. 918-927 10 p.

Research output: Contribution to journalArticle

46 Scopus citations
1999

BK channel activation by brief depolarizations requires Ca2+ influx through L- and Q-type Ca2+ channels in rat chromaffin cells

Prakriya, M. & Lingle, C. J., Jan 1 1999, In : Journal of neurophysiology. 81, 5, p. 2267-2278 12 p.

Research output: Contribution to journalArticle

76 Scopus citations
2000

Activation of BK channels in rat chromaffin cells requires summation of Ca2+ influx from multiple Ca2+ channels

Prakriya, M. & Lingle, C. J., 2000, In : Journal of neurophysiology. 84, 3, p. 1123-1135 13 p.

Research output: Contribution to journalArticle

50 Scopus citations

Selective depression of low-release probability excitatory synapses by sodium channel blockers

Prakriya, M. & Mennerick, S., Jan 1 2000, In : Neuron. 26, 3, p. 671-682 12 p.

Research output: Contribution to journalArticle

85 Scopus citations
2001
396 Scopus citations
2002

Erratum: (Journal of General Physiology (May 2002) 119:5 (487-508))

Prakiya, M. & Lewis, R. S., Jun 20 2002, In : Journal of General Physiology. 119, 6, 1 p.

Research output: Contribution to journalComment/debate

Separation and characterization of currents through store-operated CRAC channels and Mg2+-inhibited cation (MIC) channels

Prakriya, M. & Lewis, R. S., May 27 2002, In : Journal of General Physiology. 119, 5, p. 487-507 21 p.

Research output: Contribution to journalArticle

246 Scopus citations
2003

CRAC channels: Activation, permeation, and the search for a molecular identity

Prakriya, M. & Lewis, R. S., Jan 1 2003, In : Cell Calcium. 33, 5-6, p. 311-321 11 p.

Research output: Contribution to journalReview article

136 Scopus citations
2004

Store-operated calcium channels: properties, functions and the search for a molecular mechanism.

Prakriya, M. & Lewis, RS., 2004, Molecular and Cellular Insights into Ion Channel Biology. Maue, R. (ed.). Amsterdam: Elsevier Science, p. 121-140

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations
2005

Activation of GPCRs modulates quantal size in chromaffin cells through Gβγ and PKC

Chen, X. K., Wang, L. C., Zhou, Y., Cai, Q., Prakriya, M., Duan, K. L., Sheng, Z. H., Lingle, C. & Zhou, Z., Sep 1 2005, In : Nature neuroscience. 8, 9, p. 1160-1168 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients

Feske, S., Prakriya, M., Rao, A. & Lewis, R. S., Sep 5 2005, In : Journal of Experimental Medicine. 202, 5, p. 651-662 12 p.

Research output: Contribution to journalArticle

178 Scopus citations
2006

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Feske, S., Gwack, Y., Prakriya, M., Srikanth, S., Puppel, S. H., Tanasa, B., Hogan, P. G., Lewis, R. S., Daly, M. & Rao, A., May 11 2006, In : Nature. 441, 7090, p. 179-185 7 p.

Research output: Contribution to journalArticle

1587 Scopus citations

Orai1 is an essential pore subunit of the CRAC channel

Prakriya, M., Feske, S., Gwack, Y., Srikanth, S., Rao, A. & Hogan, P. G., Sep 14 2006, In : Nature. 443, 7108, p. 230-233 4 p.

Research output: Contribution to journalArticle

967 Scopus citations

Regulation of CRAC channel activity by recruitment of silent channels to a high open-probability gating mode

Prakriya, M. & Lewis, R. S., Sep 1 2006, In : Journal of General Physiology. 128, 3, p. 373-386 14 p.

Research output: Contribution to journalArticle

101 Scopus citations
2007

Orai1 mutations alter ion permeation and Ca2+-dependent fast inactivation of CRAC channels: Evidence for coupling of permeation and gating

Yamashita, M., Navarro-Borelly, L., McNally, B. A. & Prakriya, M., Nov 1 2007, In : Journal of General Physiology. 130, 5, p. 525-540 16 p.

Research output: Contribution to journalArticle

102 Scopus citations
2008

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

Oh-hora, M., Yamashita, M., Hogan, P. G., Sharma, S., Lamperti, E., Chung, W., Prakriya, M., Feske, S. & Rao, A., Apr 1 2008, In : Nature Immunology. 9, 4, p. 432-443 12 p.

Research output: Contribution to journalArticle

411 Scopus citations

Hair loss and defective T- and B-cell function in mice lacking ORAI1

Gwack, Y., Srikanth, S., Oh-hora, M., Hogan, P. G., Lamperti, E. D., Yamashita, M., Gelinas, C., Neems, D. S., Sasaki, Y., Feske, S., Prakriya, M., Rajewsky, K. & Rao, A., Sep 1 2008, In : Molecular and cellular biology. 28, 17, p. 5209-5222 14 p.

Research output: Contribution to journalArticle

217 Scopus citations

Neuronal and Glial signaling

Prakriya, M. & Miller, RJ., 2008, Neuroimmune Pharmacology.. Tsuneya, I. & Gendelman, H. (eds.). New York: Springer, p. 105-121

Research output: Chapter in Book/Report/Conference proceedingChapter

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

Luik, R. M., Wang, B., Prakriya, M., Wu, M. M. & Lewis, R. S., Jul 24 2008, In : Nature. 454, 7203, p. 538-542 5 p.

Research output: Contribution to journalArticle

376 Scopus citations

STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

Navarro-Borelly, L., Somasundaram, A., Yamashita, M., Ren, D., Miller, R. J. & Prakriya, M., Nov 15 2008, In : Journal of Physiology. 586, 22, p. 5383-5401 19 p.

Research output: Contribution to journalArticle

159 Scopus citations
2009

Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines

Woolfrey, K. M., Srivastava, D. P., Photowala, H., Yamashita, M., Barbolina, M. V., Cahill, M. E., Xie, Z., Jones, K. A., Quilliam, L. A., Prakriya, M. & Penzes, P., Oct 1 2009, In : Nature Neuroscience. 12, 10, p. 1275-1284 10 p.

Research output: Contribution to journalArticle

117 Scopus citations

Structural determinants of ion permeation in CRAC channels

McNally, B. A., Yamashita, M., Engh, A. & Prakriya, M., Dec 19 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 52, p. 22516-22521 6 p.

Research output: Contribution to journalArticle

115 Scopus citations

The molecular physiology of CRAC channels

Prakriya, M., Sep 1 2009, In : Immunological Reviews. 231, 1, p. 88-98 11 p.

Research output: Contribution to journalReview article

85 Scopus citations
2010

Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection

McCarl, C. A., Khalil, S., Ma, J., Oh-Hora, M., Yamashita, M., Roether, J., Kawasaki, T., Jairaman, A., Sasaki, Y., Prakriya, M. & Feske, S., Nov 15 2010, In : Journal of Immunology. 185, 10, p. 5845-5858 14 p.

Research output: Contribution to journalArticle

92 Scopus citations
2011

Competitive modulation of Ca2+ release-activated Ca2+ channel gating by STIM1 and 2-aminoethyldiphenyl borate

Yamashita, M., Somasundaram, A. & Prakriya, M., Mar 18 2011, In : Journal of Biological Chemistry. 286, 11, p. 9429-9442 14 p.

Research output: Contribution to journalArticle

39 Scopus citations

Hypoxia leads to Na,K-ATPase downregulation via Ca 2+ release-activated Ca 2+ channels and AMPK activation

Gusarova, G. A., Trejo, H. E., Dada, L. A., Briva, A., Welch, L. C., Hamanaka, R. B., Mutlu, G. M., Chandel, N. S., Prakriya, M. & Sznajder, J. I., Sep 1 2011, In : Molecular and cellular biology. 31, 17, p. 3546-3556 11 p.

Research output: Contribution to journalArticle

80 Scopus citations

Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels

Mungai, P. T., Waypa, G. B., Jairaman, A., Prakriya, M., Dokic, D., Ball, M. K. & Schumacker, P. T., Sep 1 2011, In : Molecular and cellular biology. 31, 17, p. 3531-3545 15 p.

Research output: Contribution to journalArticle

217 Scopus citations

The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling

Hobbs, R. P., Amargo, E. V., Somasundaram, A., Simpson, C. L., Prakriya, M., Denning, M. F. & Green, K. J., Mar 1 2011, In : FASEB Journal. 25, 3, p. 990-1001 12 p.

Research output: Contribution to journalArticle

43 Scopus citations
2012

Gated regulation of CRAC channel ion selectivity by STIM1

McNally, B. A., Somasundaram, A., Yamashita, M. & Prakriya, M., Feb 9 2012, In : Nature. 482, 7384, p. 241-245 5 p.

Research output: Contribution to journalArticle

145 Scopus citations

Ion channels and transporters in lymphocyte function and immunity

Feske, S., Skolnik, E. Y. & Prakriya, M., Jul 1 2012, In : Nature Reviews Immunology. 12, 7, p. 532-547 16 p.

Research output: Contribution to journalReview article

237 Scopus citations

Permeation, selectivity and gating in store-operated CRAC channels

McNally, B. A. & Prakriya, M., Sep 1 2012, In : Journal of Physiology. 590, 17, p. 4179-4191 13 p.

Research output: Contribution to journalReview article

41 Scopus citations

Permeation and gating mechanisms in store-operated CRAC channels

Engh, A., Somasundaram, A. & Prakriya, M., Jan 1 2012, In : Frontiers in Bioscience. 17, 5, p. 1613-1626 14 p.

Research output: Contribution to journalReview article

13 Scopus citations
2013

Conformational dynamics of STIM1 activation

Feske, S. & Prakriya, M., Aug 1 2013, In : Nature Structural and Molecular Biology. 20, 8, p. 918-919 2 p.

Research output: Contribution to journalArticle

22 Scopus citations

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

Sena, L. A., Li, S., Jairaman, A., Prakriya, M., Ezponda, T., Hildeman, D. A., Wang, C. R., Schumacker, P. T., Licht, J. D., Perlman, H., Bryce, P. J. & Chandel, N. S., Feb 21 2013, In : Immunity. 38, 2, p. 225-236 12 p.

Research output: Contribution to journalArticle

455 Scopus citations

Molecular pharmacology of store-operated CRAC channels

Jairaman, A. & Prakriya, M., Sep 1 2013, In : Channels. 7, 5, p. 402-414 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Preface

Prakriya, M., Aug 1 2013, In : Current Topics in Membranes. 71

Research output: Contribution to journalEditorial

Preface

Prakriya, M., Aug 1 2013, In : Current topics in membranes. 71

Research output: Contribution to journalEditorial

2 Scopus citations

Store-Operated Orai Channels: Structure and Function

Prakriya, M., 2013, Current Topics in Membranes. Academic Press Inc, p. 1-32 32 p. (Current Topics in Membranes; vol. 71).

Research output: Chapter in Book/Report/Conference proceedingChapter

45 Scopus citations

The C- and N-terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels

Mcnally, B. A., Somasundaram, A., Jairaman, A., Yamashita, M. & Prakriya, M., Jun 1 2013, In : Journal of Physiology. 591, 11, p. 2833-2850 18 p.

Research output: Contribution to journalArticle

73 Scopus citations
2014

Calcium release-activated calcium (CRAC) channels mediate the β2-adrenergic regulation of Na,K-ATPase

Keller, M. J., Lecuona, E., Prakriya, M., Cheng, Y., Soberanes, S., Budinger, G. R. S. & Sznajder, J. I., Dec 20 2014, In : FEBS Letters. 588, 24, p. 4686-4693 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
27 Scopus citations

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells

Somasundaram, A., Shum, A. K., McBride, H. J., Kessler, J. A., Feske, S., Miller, R. J. & Prakriya, M., 2014, In : Journal of Neuroscience. 34, 27, p. 9107-9123 17 p.

Research output: Contribution to journalArticle

71 Scopus citations
2015

Conformational changes in the Orai1 C-terminus evoked by STIM1 binding

Tirado-Lee, L., Yamashita, M. & Prakriya, M., Jun 2 2015, In : PloS one. 10, 6, e0128622.

Research output: Contribution to journalArticle

31 Scopus citations