Neha P. Kamat

  • 594 Citations
20102023
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Personal profile

Research Interests

Our interests lie in constructing minimal systems, or artificial cells, as a tool to understand and recreate certain cellular behaviors. We are specifically interested in designing mechanically responsive systems that can optically or enzymatically report membrane stress in biological and polymeric environments. By using emerging engineering methods in material science and synthetic biology, we aim to construct macromolecular assemblies that can coordinate both membrane biophysical processes and RNA-regulated chemical processes in order to continuously sense and respond to designed stimuli for medicinal and technological applications.

Education/Academic qualification

Bioengineering, PhD, University of Pennsylvania

… → 2012

Bioengineering, Magna Cum Laude, BS, Rice University

… → 2008

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Membranes Chemical Compounds
Artificial Cells Medicine & Life Sciences
RNA Engineering & Materials Science
Peptides Engineering & Materials Science
Fatty acids Engineering & Materials Science
Polymers Chemical Compounds
Copying Chemical Compounds
Fatty Acids Chemical Compounds

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Grants 2018 2023

Research Output 2010 2019

  • 594 Citations
  • 17 Article
  • 1 Conference contribution
  • 1 Comment/debate
  • 1 Review article

A membrane logic gate to control secretion from vesicles

Hilburger, C. H., Lewis, K. L., Jacobs, M. L. & Kamat, N. P., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Logic gates
Hemolysin Proteins
Membranes
Proteins
Cell-Free System
Open Access
Membrane Proteins
Membranes
Artificial Cells
Protein Folding
Biosensing Techniques
8 Citations (Scopus)

Copying of Mixed-Sequence RNA Templates inside Model Protocells

O'Flaherty, D. K., Kamat, N. P., Mirza, F. N., Li, L., Prywes, N. & Szostak, J. W., Apr 18 2018, In : Journal of the American Chemical Society. 140, 15, p. 5171-5178 8 p.

Research output: Contribution to journalArticle

Artificial Cells
Copying
RNA
Oligomers
Fatty acids
6 Citations (Scopus)

Fatty Acid/Phospholipid Blended Membranes: A Potential Intermediate State in Protocellular Evolution

Jin, L., Kamat, N. P., Jena, S. & Szostak, J. W., Apr 12 2018, In : Small. 14, 15, 1704077.

Research output: Contribution to journalArticle

Phospholipids
Fatty acids
Membrane Potentials
Fatty Acids
Membranes
2 Citations (Scopus)

Visualizing Tension and Growth in Model Membranes Using Optical Dyes

Boyd, M. A. & Kamat, N. P., Oct 2 2018, In : Biophysical Journal. 115, 7, p. 1307-1315 9 p.

Research output: Contribution to journalArticle

Coloring Agents
Membranes
Growth
Surface Tension
Membrane Lipids