Grants per year
Personal profile
Research Interests
Our interests lie in constructing minimal systems, or artificial cells, as a tool to understand and recreate certain cellular behaviors. We are specifically interested in designing mechanically responsive systems that can optically or enzymatically report membrane stress in biological and polymeric environments. By using emerging engineering methods in material science and synthetic biology, we aim to construct macromolecular assemblies that can coordinate both membrane biophysical processes and RNA-regulated chemical processes in order to continuously sense and respond to designed stimuli for medicinal and technological applications.
Education/Academic qualification
Bioengineering, PhD, University of Pennsylvania
… → 2012
Bioengineering, Magna Cum Laude, BS, Rice University
… → 2008
Research interests
- Artificial cells
- Biomaterials
- Membrane Biophysics
- Polymersomes
- RNA
Fingerprint Dive into the research topics where Neha P. Kamat is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Membranes
Chemical Compounds
Artificial Cells
Medicine & Life Sciences
RNA
Engineering & Materials Science
Peptides
Engineering & Materials Science
Phospholipids
Engineering & Materials Science
Fatty acids
Engineering & Materials Science
Fatty Acids
Chemical Compounds
Polymers
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2018 2023
- 5 Active
Fatty acids in cellular membranes nonspecifically impact cardiovascular function though Piezo1 activity
1/1/20 → 12/31/21
Project: Research project
Fatty Acids
Membranes
Unsaturated Fatty Acids
Membrane Proteins
Proteins
Collaborative Research: EAGER: Uncovering the role of Golgi organization on function
8/15/19 → 7/31/21
Project: Research project
enzyme
membrane
vesicle
lipid
protein
A Biophysical Approach to Uncover the Role of Cell Membrane Mechanics in Sensing Mechanical Force
Air Force Office of Scientific Research
1/1/19 → 12/31/21
Project: Research project
Mechanics
Cell Membrane
Ion Channels
Membranes
Elasticity
RoL: EAGER: DESYN-C3 Moving information across synthetic membranes via engineered sensors
12/1/18 → 11/30/20
Project: Research project
Membranes
Sensors
Chemical reactions
Cells
Catalysts
RoL: RAISE: DESYN-C3: A platform for Modular Pseudo-Organelles for Compartmentalization and Control of Pseudo-Cell Processes
Bagheri, N., Ercek, D. T. & Kamat, N. P.
9/15/18 → 8/31/23
Project: Research project
Chassis
Communication
Metabolism
Networks (circuits)
Research Output 2010 2019
A membrane logic gate to control secretion from vesicles
Hilburger, C. H., Lewis, K. L., Jacobs, M. L. & Kamat, N. P., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Logic gates
Hemolysin Proteins
Membranes
Proteins
Cell-Free System
1
Citation
(Scopus)
Barcoding Biological Reactions with DNA-Functionalized Vesicles
Peruzzi, J. A., Jacobs, M. L., Vu, T. Q., Wang, K. S. & Kamat, N. P., Dec 16 2019, In : Angewandte Chemie - International Edition. 58, 51, p. 18683-18690 8 p.Research output: Contribution to journal › Article
DNA
Fusion reactions
Membranes
Proteins
Membrane Proteins
1
Citation
(Scopus)
Controlling Secretion in Artificial Cells with a Membrane and Gate
Hilburger, C. E., Jacobs, M. L., Lewis, K. R., Peruzzi, J. A. & Kamat, N. P., Jun 21 2019, In : ACS synthetic biology. 8, 6, p. 1224-1230 7 p.Research output: Contribution to journal › Article
Artificial Cells
Membranes
Hemolysin Proteins
Oleic acid
Phospholipids
5
Citations
(Scopus)
Diblock copolymers enhance folding of a mechanosensitive membrane protein during cell-free expression
Jacobs, M. L., Boyd, M. A. & Kamat, N. P., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4031-4036 6 p.Research output: Contribution to journal › Article
Open Access
Membrane Proteins
Membranes
Artificial Cells
Protein Folding
Biosensing Techniques
19
Citations
(Scopus)
Copying of Mixed-Sequence RNA Templates inside Model Protocells
O'Flaherty, D. K., Kamat, N. P., Mirza, F. N., Li, L., Prywes, N. & Szostak, J. W., Apr 18 2018, In : Journal of the American Chemical Society. 140, 15, p. 5171-5178 8 p.Research output: Contribution to journal › Article
Artificial Cells
Copying
RNA
Oligomers
Fatty acids