Grants per year
Personal profile
Research Interests
Our interests lie in constructing minimal systems, or artificial cells, as a tool to understand and recreate certain cellular behaviors. We are specifically interested in designing mechanically responsive systems that can optically or enzymatically report membrane stress in biological and polymeric environments. By using emerging engineering methods in material science and synthetic biology, we aim to construct macromolecular assemblies that can coordinate both membrane biophysical processes and RNA-regulated chemical processes in order to continuously sense and respond to designed stimuli for medicinal and technological applications.
Education/Academic qualification
Bioengineering, PhD, University of Pennsylvania
… → 2012
Bioengineering, Magna Cum Laude, BS, Rice University
… → 2008
Research interests
- Artificial cells
- Biomaterials
- Membrane Biophysics
- Polymersomes
- RNA
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Cell-free Biomanufacturing Institute
Jewett, M. C., Gianneschi, N., Mrksich, M., Olvera de la Cruz, M., Broadbelt, L. J., Farha, O. K., Kamat, N. P., Lucks, J. B., Mangan, N. M., Tullman-Ercek, D. & Tyo, K. E. J.
9/29/21 → 9/28/22
Project: Research project
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Self-Assembling Cell-Free Systems for Scalable Bioconversion
University of Washington, Advanced Research Projects Agency - Energy
8/25/21 → 8/24/23
Project: Research project
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NRT-URoL: Synthesizing Biology Across Scales – A Convergent Synthetic Biology Training Program
Lucks, J. B., Calkins, S. C., Jewett, M. C., Kamat, N. P., Tullman-Ercek, D., Leonard, J. N., Mangan, N. M., Prindle, A. & Tyo, K. E. J.
9/1/20 → 8/31/25
Project: Research project
Research Output
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Bioinspired Macromolecular Materials
Webber, M. J., Kamat, N. P., Messersmith, P. B. & Lecommandoux, S., Jan 11 2021, In: Biomacromolecules. 22, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Cell-Free Synthesis of a Transmembrane Mechanosensitive Channel Protein into a Hybrid-Supported Lipid Bilayer
Manzer, Z. A., Ghosh, S., Jacobs, M. L., Krishnan, S., Zipfel, W. R., Pineros, M., Kamat, N. P. & Daniel, S., Apr 19 2021, In: ACS Applied Bio Materials. 4, 4, p. 3101-3112 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Designing Artificial Cells towards a New Generation of Biosensors
Boyd, M. A. & Kamat, N. P., Sep 2021, In: Trends in biotechnology. 39, 9, p. 927-939 13 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
EPA and DHA differentially modulate membrane elasticity in the presence of cholesterol
Jacobs, M. L., Faizi, H. A., Peruzzi, J. A., Vlahovska, P. M. & Kamat, N. P., Jun 1 2021, In: Biophysical Journal. 120, 11, p. 2317-2329 13 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles
Hershewe, J. M., Warfel, K. F., Iyer, S. M., Peruzzi, J. A., Sullivan, C. J., Roth, E. W., DeLisa, M. P., Kamat, N. P. & Jewett, M. C., Dec 2021, In: Nature communications. 12, 1, 2363.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations