Grants per year
Personal profile
Research Interests
Our interests lie in constructing minimal systems, or artificial cells, as a tool to understand and recreate certain cellular behaviors. We are specifically interested in designing mechanically responsive systems that can optically or enzymatically report membrane stress in biological and polymeric environments. By using emerging engineering methods in material science and synthetic biology, we aim to construct macromolecular assemblies that can coordinate both membrane biophysical processes and RNA-regulated chemical processes in order to continuously sense and respond to designed stimuli for medicinal and technological applications.
Education/Academic qualification
Bioengineering, PhD, University of Pennsylvania
… → 2012
Bioengineering, Magna Cum Laude, BS, Rice University
… → 2008
Research interests
- Artificial cells
- Biomaterials
- Membrane Biophysics
- Polymersomes
- RNA
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants
Fatty acids in cellular membranes nonspecifically impact cardiovascular function though Piezo1 activity
1/1/20 → 12/31/21
Project: Research project
Collaborative Research: EAGER: Uncovering the role of Golgi organization on function
8/15/19 → 7/31/21
Project: Research project
A Biophysical Approach to Uncover the Role of Cell Membrane Mechanics in Sensing Mechanical Force
Air Force Office of Scientific Research
1/1/19 → 12/31/21
Project: Research project
RoL: EAGER: DESYN-C3 Moving information across synthetic membranes via engineered sensors
12/1/18 → 11/30/20
Project: Research project
RoL: RAISE: DESYN-C3: A platform for Modular Pseudo-Organelles for Compartmentalization and Control of Pseudo-Cell Processes
Bagheri, N., Ercek, D. T. & Kamat, N. P.
9/15/18 → 8/31/23
Project: Research project
Research Output
Energy Dissipation at Interfaces Drives Multicompartment Remodeling
Steinkühler, J. & Kamat, N. P., May 14 2020, In : Chem. 6, 5, p. 1051-1052 2 p.Research output: Contribution to journal › Article
A membrane logic gate to control secretion from vesicles
Hilburger, C. H., Lewis, K. L., Jacobs, M. L. & Kamat, N. P., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Barcoding Biological Reactions with DNA-Functionalized Vesicles
Peruzzi, J. A., Jacobs, M. L., Vu, T. Q., Wang, K. S. & Kamat, N. P., Dec 16 2019, In : Angewandte Chemie - International Edition. 58, 51, p. 18683-18690 8 p.Research output: Contribution to journal › Article
1
Scopus
citations
Controlling Secretion in Artificial Cells with a Membrane and Gate
Hilburger, C. E., Jacobs, M. L., Lewis, K. R., Peruzzi, J. A. & Kamat, N. P., Jun 21 2019, In : ACS synthetic biology. 8, 6, p. 1224-1230 7 p.Research output: Contribution to journal › Article
3
Scopus
citations
Diblock copolymers enhance folding of a mechanosensitive membrane protein during cell-free expression
Jacobs, M. L., Boyd, M. A. & Kamat, N. P., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4031-4036 6 p.Research output: Contribution to journal › Article
Open Access
12
Scopus
citations