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Personal profile

Education/Academic qualification

PhD, Cornell University

… → 1997

Fingerprint Dive into the research topics where Neil L Kelleher is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Mass spectrometry Chemical Compounds
Mass Spectrometry Medicine & Life Sciences
Proteomics Medicine & Life Sciences
Proteins Chemical Compounds
Biosynthesis Chemical Compounds
Histones Medicine & Life Sciences
Peptide Synthases Medicine & Life Sciences
Biological Products Medicine & Life Sciences

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Grants 2010 2024

Tissue
Antibodies
Biomolecules
Mass spectrometry
Proteins
Amyloid
Alzheimer Disease
Post Translational Protein Processing
Peptides
Data Mining
Cell signaling
Bioinformatics
Proteins
Mass spectrometers
Sampling
Mass spectrometry

Research Output 1994 2019

3 Citations (Scopus)

Accurate estimation of context-dependent false discovery rates in top-down proteomics

LeDuc, R. D., Fellers, R. T., Early, B. P., Greer, J. B., Shams, D. P., Thomas, P. M. & Kelleher, N. L., Jan 1 2019, In : Molecular and Cellular Proteomics. 18, 4, p. 796-805 10 p.

Research output: Contribution to journalArticle

Proteomics
Search Engine
Search engines
Protein Isoforms
Proteins
6 Citations (Scopus)

A comprehensive pipeline for translational top-down proteomics from a single blood draw

Toby, T. K., Fornelli, L., Srzentić, K., DeHart, C. J., Levitsky, J., Friedewald, J. J. & Kelleher, N. L., Jan 1 2019, In : Nature Protocols. 14, 1, p. 119-152 34 p.

Research output: Contribution to journalArticle

Proteomics
Blood
Pipelines
Fractionation
Mass spectrometry
1 Citation (Scopus)

A five-level classification system for proteoform identifications

Smith, L. M., Thomas, P. M., Shortreed, M. R., Schaffer, L. V., Fellers, R. T., LeDuc, R. D., Tucholski, T., Ge, Y., Agar, J. N., Anderson, L. C., Chamot-Rooke, J., Gault, J., Loo, J. A., Paša-Tolić, L., Robinson, C. V., Schlüter, H., Tsybin, Y. O., Vilaseca, M., Vizcaíno, J. A., Danis, P. O. & 1 others, Kelleher, N. L., Oct 1 2019, In : Nature Methods. 16, 10, p. 939-940 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

A mutation in histone H2B represents a new class of oncogenic driver

Bennett, R. L., Bele, A., Small, E. C., Will, C. M., Nabet, B., Oyer, J. A., Huang, X., Ghosh, R. P., Grzybowski, A. T., Yu, T., Zhang, Q., Riva, A., Lele, T. P., Schatz, G. C., Kelleher, N. L., Ruthenburg, A. J., Liphardt, J. & Licht, J. D., Oct 2019, In : Cancer discovery. 9, 10, p. 1438-1451 14 p.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Mutation
Gene Expression
Chromatin
5 Citations (Scopus)

An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia

Swaroop, A., Oyer, J. A., Will, C. M., Huang, X., Yu, W., Troche, C., Bulic, M., Durham, B. H., Wen, Q., Crispino, J. D., MacKerell, A. D., Bennett, R. L., Kelleher, N. L. & Licht, J. D., Jan 31 2019, In : Oncogene. 38, 5, p. 671-686 16 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mutation
Histones
Methylation
Lysine