Grants per year
Personal profile
Research Interests
Our laboratory studies Legionella pneumophila, the bacterial agent of Legionnaires' Disease pneumonia and Pontiac Fever. Research efforts include understanding the protein secretion systems and iron acquisition pathways that contribute to the organism's ability to infect host cells and the lung. Our laboratory has also identified a new species of Legionella (L. cardiaca) that is linked to heart infection. Finally, we study Stenotrophomonas maltophilia and Klebsiella pneumonia, highly antibiotic resistant bacteria that are increasingly associated with human infections.
Training Experience
| 1989 | Postdoctoral Fellowship, University of Michigan |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, University of Washington
… → 1986
Research interests
- Bacterial Pathogenesis
- Bacteriology
- Cellular Microbiology
- Genetics: Microbial
- Infectious Diseases: Bacteria
- Microbiology
- Pneumonia
- Prokaryotic Cells
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Siderophores of Legionella pneumophila
National Institute of Allergy and Infectious Diseases
7/23/18 → 6/30/23
Project: Research project
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Reassessing Legionella pneumophila Recognition during Intracellular Infection of Human Macrophages
National Institute of Allergy and Infectious Diseases
11/15/18 → 10/31/21
Project: Research project
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Immunology and Molecular Pathogenesis Training Program
National Institute of Allergy and Infectious Diseases
9/1/17 → 8/31/22
Project: Research project
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Assay for assessing mucin binding to bacteria and bacterial proteins
Grigoryeva, L. S., Rehman, S., White, R. C., Garnett, J. A. & Cianciotto, N. P., Mar 5 2021, In: Bio-protocol. 11, 5, e3933.Research output: Contribution to journal › Article › peer-review
Open Access -
Effectors of the stenotrophomonas maltophilia type IV secretion system mediate killing of clinical isolates of pseudomonas aeruginosa
Nas, M. Y., Gabell, J. & Cianciotto, N. P., Jun 2021, In: mBio. 12, 3, e01502-21.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Human macrophages utilize a wide range of pathogen recognition receptors to recognize Legionella pneumophila, including Toll-Like Receptor 4 engaging Legionella lipopolysaccharide and the Toll-like Receptor 3 nucleic-acid sensor
Grigoryeva, L. S. & Cianciotto, N. P., Jul 2021, In: PLoS pathogens. 17, July, e1009781.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Publisher Correction: In vivo structure of the Legionella type II secretion system by electron cryotomography (Nature Microbiology, (2019), 4, 12, (2101-2108), 10.1038/s41564-019-0603-6)
Ghosal, D., Kim, K. W., Zheng, H., Kaplan, M., Truchan, H. K., Lopez, A. E., McIntire, I. E., Vogel, J. P., Cianciotto, N. P. & Jensen, G. J., Apr 1 2020, In: Nature Microbiology. 5, 4, p. 651 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Structure, Dynamics and Cellular Insight Into Novel Substrates of the Legionella pneumophila Type II Secretion System
Portlock, T. J., Tyson, J. Y., Dantu, S. C., Rehman, S., White, R. C., McIntire, I. E., Sewell, L., Richardson, K., Shaw, R., Pandini, A., Cianciotto, N. P. & Garnett, J. A., Jun 11 2020, In: Frontiers in Molecular Biosciences. 7, 112.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations