Grants per year
Personal profile
Research Interests
Our laboratory studies Legionella pneumophila, the bacterial agent of Legionnaires' Disease pneumonia and Pontiac Fever. Research efforts include understanding the protein secretion systems and iron acquisition pathways that contribute to the organism's ability to infect host cells and the lung. Our laboratory has also identified a new species of Legionella (L. cardiaca) that is linked to heart infection. Finally, we study Stenotrophomonas maltophilia and Klebsiella pneumonia, highly antibiotic resistant bacteria that are increasingly associated with human infections.
Training Experience
| 1989 | Postdoctoral Fellowship, University of Michigan |
Education/Academic qualification
PhD, University of Washington
… → 1986
Research interests
- Bacterial Pathogenesis
- Bacteriology
- Cellular Microbiology
- Genetics: Microbial
- Infectious Diseases: Bacteria
- Microbiology
- Pneumonia
- Prokaryotic Cells
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants
Reassessing Legionella pneumophila Recognition during Intracellular Infection of Human Macrophages
National Institute of Allergy and Infectious Diseases
11/15/18 → 10/31/20
Project: Research project
Siderophores of Legionella pneumophila
National Institute of Allergy and Infectious Diseases
7/23/18 → 6/30/22
Project: Research project
Immunology and Molecular Pathogenesis Training Program
National Institute of Allergy and Infectious Diseases
9/1/17 → 8/31/22
Project: Research project
Research Output
Publisher Correction: In vivo structure of the Legionella type II secretion system by electron cryotomography (Nature Microbiology, (2019), 4, 12, (2101-2108), 10.1038/s41564-019-0603-6)
Ghosal, D., Kim, K. W., Zheng, H., Kaplan, M., Truchan, H. K., Lopez, A. E., McIntire, I. E., Vogel, J. P., Cianciotto, N. P. & Jensen, G. J., Apr 1 2020, In : Nature Microbiology. 5, 4, 1 p.Research output: Contribution to journal › Comment/debate
Open Access
Analysis of iron requirements and siderophore production
Burnside, D. M. & Cianciotto, N. P., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc, p. 3-19 17 p. (Methods in Molecular Biology; vol. 1921).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Assessing the impact, genomics and evolution of type II secretion across a large, medically important genus: The Legionella type II secretion paradigm
White, R. C. & Cianciotto, N. P., Jul 2019, In : Microbial Genomics. 5, 6, p. 1-30 30 p.Research output: Contribution to journal › Article
Open Access
6
Scopus
citations
In vivo structure of the Legionella type II secretion system by electron cryotomography
Ghosal, D., Kim, K. W., Zheng, H., Kaplan, M., Truchan, H. K., Lopez, A. E., McIntire, I. E., Vogel, J. P., Cianciotto, N. P. & Jensen, G. J., Dec 1 2019, In : Nature Microbiology. 4, 12, p. 2101-2108 8 p.Research output: Contribution to journal › Article
1
Scopus
citations
Stenotrophomonas maltophilia encodes a VirB/VirD4 type IV secretion system that modulates apoptosis in human cells and promotes competition against heterologous bacteria, including Pseudomonas aeruginosa
Nas, M. Y., White, R. C., DuMont, A. L., Lopez, A. E. & Cianciottoa, N. P., Sep 1 2019, In : Infection and immunity. 87, 9, e00457-19.Research output: Contribution to journal › Article
3
Scopus
citations