Nicolas F M Porta

Personal profile

Research Interests

I am interested in the impact of pulmonary vascular disease in pediatric patients. Through clinical and research efforts, I have been studying the role of pulmonary hypertension and pulmonary vascular disease in neonatal patients with lung diseases (including bronchopulmonary dysplasia (BPD), congenital diaphragmatic hernia (CDH)) by evaluating for interactions between the respiratory and circulatory dysfunction. Collaborations with other researchers and clinicians has led to the development of programmatic approaches for these patients.

My research interests include clinical characterization of and management strategies for children with pulmonary vascular disease, including infants with chronic respiratory failure associated with prematurity or congenital anomalies.

My clinical efforts focus on the care of critically ill neonates, and children with pulmonary hypertension. As a neonatologist, I am particularly interested in infants with chronic respiratory failure, the use of advanced strategies for mechanical ventilation, and invasive evaluation of causes and degrees of respiratory dysfunction. As Co-Director for the Pediatric Pulmonary Hypertension Program, I am involved in the evaluation and management of children with pulmonary hypertension, including the use of aggressive and combination pulmonary vasodilator medications and other strategies.

Certifications and Licenses

	General Pediatrics
	Neonatal-Perinatal Medicine

Training Experience

1996	Residency, Univ. of Chicago Hospital
1999	Fellowship, Univ. of California-San Francisco

Education/Academic qualification

MD, University of Illinois at Chicago

… → 1993

Research interests

Cardiovascular System
Congenital Malformations
Neonatology
Pediatric Critical Care
Pediatric Pulmonology
Pediatrics
Respiratory Diseases

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Grants

1 Active
8 Finished

Intravenous Remodulin (Treprostinil) as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn: A Randomized, Placebo-Controlled, Safety and Efficacy Study

Porta, N. F. M.

United Therapeutics Corp

3/15/16 → 3/31/20

Project: Research project

Multi-centered non-drug-interventional extension study to assess long-term safety and effects on growth in patients who receive Bosentan or placebo as adjunctive therapy to inhaled nitric oxide for persistent pulmonary hyoperte

Porta, N. F. M.

Actelion Pharmaceuticals, Inc.

4/24/14 → 8/31/15

Project: Research project

A1481316: A multi-centre, randomized, placebo-controlled, double blind, two-armed, parallel-group study to evaluate the efficacy and safety of iv sildenafil in the treatment of neonates with persistent pulmonary hyperetnsion of

Porta, N. F. M.

Pfizer Inc.

1/24/14 → 1/24/15

Project: Research project

TyTRATE Registry: A Patient Registry to Observe the Real-World Dosing and Titration of Tyvaso

Porta, N. F. M.

United Therapeutics Corp

6/17/13 → 6/15/15

Project: Research project

Trial of Late SURFactant (TOLSURF) to prevent BPD

Porta, N. F. M.

Northwestern University, National Heart, Lung, and Blood Institute

8/1/12 → 6/30/16

Project: Research project

Research Output

803 Citations
26 Article
4 Chapter
4 Review article

Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia

on behalf of the Children’s Hospitals Neonatal Consortium Severe BPD Focus Group, Jan 1 2020, In : Journal of Perinatology. 40, 1, p. 149-156 8 p.