Grants per year
Personal profile
Research Interests
I am interested in the impact of pulmonary vascular disease in pediatric patients. Through clinical and research efforts, I have been studying the role of pulmonary hypertension and pulmonary vascular disease in neonatal patients with lung diseases (including bronchopulmonary dysplasia (BPD), congenital diaphragmatic hernia (CDH)) by evaluating for interactions between the respiratory and circulatory dysfunction. Collaborations with other researchers and clinicians has led to the development of programmatic approaches for these patients.
My research interests include clinical characterization of and management strategies for children with pulmonary vascular disease, including infants with chronic respiratory failure associated with prematurity or congenital anomalies.
My clinical efforts focus on the care of critically ill neonates, and children with pulmonary hypertension. As a neonatologist, I am particularly interested in infants with chronic respiratory failure, the use of advanced strategies for mechanical ventilation, and invasive evaluation of causes and degrees of respiratory dysfunction. As Co-Director for the Pediatric Pulmonary Hypertension Program, I am involved in the evaluation and management of children with pulmonary hypertension, including the use of aggressive and combination pulmonary vasodilator medications and other strategies.
Certifications and Licenses
General Pediatrics | |
Neonatal-Perinatal Medicine |
Training Experience
1996 | Residency, Univ. of Chicago Hospital |
1999 | Fellowship, Univ. of California-San Francisco |
Education/Academic qualification
MD, University of Illinois at Chicago
… → 1993
Medicine, MD, University of Illinois at Chicago
… → 1993
Research interests
- Cardiovascular System
- Congenital Malformations
- Neonatology
- Pediatric Critical Care
- Pediatric Pulmonology
- Pediatrics
- Respiratory Diseases
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Grants
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TyTRATE Registry: A Patient Registry to Observe the Real-World Dosing and Titration of Tyvaso
United Therapeutics Corporation
6/17/13 → 6/15/15
Project: Research project
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Trial of Late SURFactant (TOLSURF) to prevent BPD
Northwestern University, National Heart, Lung, and Blood Institute
8/1/12 → 6/30/16
Project: Research project
Research Output
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Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia
on behalf of the Children’s Hospitals Neonatal Consortium Severe BPD Focus Group, Jan 1 2020, In: Journal of Perinatology. 40, 1, p. 149-156 8 p.Research output: Contribution to journal › Article › peer-review
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Extracorporeal membrane oxygenation and bloodstream infection in congenital diaphragmatic hernia
on behalf of the Children’s Hospitals Neonatal Consortium’s (CHNC) Congenital Diaphragmatic Hernia Focus Group, Oct 1 2019, In: Journal of Perinatology. 39, 10, p. 1384-1391 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Acquired Infection and Antimicrobial Utilization during Initial NICU Hospitalization in Infants with Congenital Diaphragmatic Hernia
Keene, S., Murthy, K., Pallotto, E., Brozanski, B., Gien, J., Zaniletti, I., Hulbert, C., Seabrook, R., Rintoul, N., Chicoine, L., Porta, N. & Grover, T. R., May 1 2018, In: Pediatric Infectious Disease Journal. 37, 5, p. 469-474 6 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants
TOLSURF Study Group, Nov 1 2018, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 5, p. L858-L869Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Predicting Risk of Infection in Infants with Congenital Diaphragmatic Hernia
Children's Hospitals Neonatal Consortium (CHNC) Congenital Diaphragmatic Hernia Focus Group, Dec 2018, In: Journal of Pediatrics. 203, p. 101-107.e2Research output: Contribution to journal › Article › peer-review
1 Scopus citations