Keyphrases
Dravet Syndrome
100%
Mouse Model
99%
SCN1A
92%
Epilepsy
47%
Seizure
46%
Genetic Modifiers
38%
Spontaneous Seizures
30%
SCN2A
25%
Modifier Loci
23%
Candidate Gene Study
21%
Anticonvulsant
18%
C57BL
17%
Epilepsy Model
17%
Epileptic Encephalopathy
16%
Hyperthermia-induced Seizure
16%
Fine Mapping
15%
Voltage-gated Sodium Channel
15%
Seizure Frequency
12%
Seizure Burden
12%
Strain-dependent
12%
Phenotype Severity
11%
Pathogenic Variants
11%
Chromosome 11
11%
Developmental Encephalopathy
11%
KCNB1
10%
RNA Sequencing (RNA-seq)
10%
Sodium Channel Modulator
10%
Persistent Sodium Current
10%
Epilepsy Phenotype
10%
Modifier Genes
10%
Seizure Phenotypes
10%
Calmodulin
9%
GS967
9%
GABAA Receptor (GABAAR)
9%
Heterozygous Deletion
8%
Neuronal Excitability
8%
Genetic Epilepsy with Febrile Seizures Plus (GEFS+)
8%
Sodium Current
8%
GABRA2
8%
129S6
8%
Premature Death
7%
Neurobehavioral Phenotype
7%
Voltage-gated Sodium Channel Gene
7%
Soticlestat
7%
Antiepileptic Drugs
6%
Mutant Mice
6%
Dominant Negative
6%
Neurological Phenotype
6%
Cannabidiol
6%
Sodium Channel
6%
Pharmacology, Toxicology and Pharmaceutical Science
Severe Myoclonic Epilepsy in Infancy
93%
Mouse Model
88%
Anticonvulsive Agent
29%
Brain Disease
24%
Hyperthermia
21%
Receptor
18%
Prematurity
14%
Sodium Channel
12%
129S6/SvEvTac Mouse
12%
Voltage Gated Sodium Channel
10%
Diseases
10%
Lethality
9%
Cannabidiol
9%
Knockout Mouse
6%
Cannabis
6%
Syndrome
6%
Seizure Susceptibility
6%
C57BL/6N Mouse
5%
Leukemia
5%
Cholesterol 24 Hydroxylase
5%
Prostaglandin
5%
Endocannabinoid System
5%
Endocannabinoid
5%
Antiepileptic Activity
5%
G Protein Coupled Receptor
5%
Drug Discovery
5%
Epileptogenesis
5%
Neuroscience
Dravet Syndrome
66%
Brain Disease
20%
Sodium Current
19%
Anticonvulsant
18%
Sodium Channel
14%
Voltage Gated Sodium Channel
13%
KCNB1
10%
Neuronal Excitability
9%
Excitability
8%
GABAA Receptor
8%
Action Potential
7%
RNA-Seq
7%
Pervasive Developmental Disorder
7%
SCN8A
7%
Generalized Epilepsy with Febrile Seizures Plus
6%
Febrile Seizure
6%
Gene Expression
6%
Receptor
6%
Chromosome 5
6%
Sodium Channel Nav1.2
6%
Behavioral Effect
5%
Brainstem
5%
Endocannabinoid System
5%
Hippocampus
5%
Pyridoxine
5%
Genetic Mapping
5%
Amygdala
5%
Synaptic Transmission
5%
Prostaglandin
5%
Ion Permeability
5%
Endocannabinoid
5%
Voltage-Gated Ion Channel
5%
Neuroactive Steroid
5%
Proteomics
5%
Protein Kinases
5%
Calmodulin
5%
Hemiplegia
5%