Nirmala Prabu Gonsalves

  • 4551 Citations
20062023
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Research Output 2006 2020

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2019
4 Citations (Scopus)

Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium

Pesek, R. D., Reed, C. C., Muir, A. B., Fulkerson, P. C., Menard-Katcher, C., Falk, G. W., Kuhl, J., Martin, E. K., Magier, A. Z., Ahmed, F., Demarshall, M., Gupta, A., Gross, J., Ashorobi, T., Carpenter, C. L., Krischer, J. P., Gonsalves, N., Spergel, J. M., Gupta, S. K., Furuta, G. T. & 2 others, Rothenberg, M. E. & Dellon, E. S., Jun 1 2019, In : American Journal of Gastroenterology. 114, 6, p. 984-994 11 p.

Research output: Contribution to journalArticle

Colitis
Gastroenteritis
Inflammation
Therapeutics
Nausea
3 Citations (Scopus)

One-Hour Esophageal String Test: A Nonendoscopic Minimally Invasive Test That Accurately Detects Disease Activity in Eosinophilic Esophagitis

Ackerman, S. J., Kagalwalla, A. F., Hirano, I., Gonsalves, N., Katcher, P. M., Gupta, S., Wechsler, J. B., Grozdanovic, M., Pan, Z., Masterson, J. C., Du, J., Fantus, R. J., Alumkal, P., Lee, J. J., Ochkur, S., Ahmed, F., Capocelli, K., Melin-Aldana, H., Biette, K., Dubner, A. & 6 others, Amsden, K., Keeley, K., Sulkowski, M., Zalewski, A., Atkins, D. & Furuta, G. T., Oct 1 2019, In : The American journal of gastroenterology. 114, 10, p. 1614-1625 12 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Eosinophils
Biomarkers
Esophagus
Digestive System Endoscopy
1 Citation (Scopus)

Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults With Eosinophilic Esophagitis

International EEsAI Study Group, Jul 2019, In : Clinical Gastroenterology and Hepatology. 17, 8, p. 1477-1488.e10

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Endoscopy
Placebos
Exudates and Transudates
Linear Models
2018
10 Citations (Scopus)

Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jul 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 130-138.e1

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Histology
Quality of Life
Parents
Pediatrics
8 Citations (Scopus)

Assessing Adherence and Barriers to Long-Term Elimination Diet Therapy in Adults with Eosinophilic Esophagitis

Wang, R., Hirano, I., Doerfler, B., Zalewski, A., Gonsalves, N. & Taft, T., Jul 1 2018, In : Digestive diseases and sciences. 63, 7, p. 1756-1762 7 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Diet Therapy
Diet
Food
Maintenance
2 Citations (Scopus)

Clinical presentation and approach to dietary management of eosinophilic esophagitis

Gonsalves, N., Dec 2018, In : Gastroenterology and Hepatology. 14, 12, p. 706-712 7 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Inflammation
Food
Heartburn
Food Hypersensitivity
9 Citations (Scopus)

Comparison of endoscopy and radiographic imaging for detection of esophageal inflammation and remodeling in adults with eosinophilic esophagitis

Nelson, M. J., Miller, F. H., Moy, N., Zalewski, A., Gonsalves, N. P., Gregory, D. L. & Hirano, I., Apr 1 2018, In : Gastrointestinal Endoscopy. 87, 4, p. 962-968 7 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Endoscopy
Inflammation
Esophageal Stenosis
Barium
31 Citations (Scopus)

Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jul 2018, In : The Lancet Gastroenterology and Hepatology. 3, 7, p. 477-488 12 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Cross-Sectional Studies
Eosinophils
Esophagus
Odds Ratio
4 Citations (Scopus)

Impact on Health-Related Quality of Life in Adults with Eosinophilic Gastritis and Gastroenteritis: A Qualitative Assessment

Bedell, A., Taft, T. N., Craven, M. R., Guadagnoli, L., Hirano, I. & Gonsalves, N. P., May 1 2018, In : Digestive diseases and sciences. 63, 5, p. 1148-1157 10 p.

Research output: Contribution to journalArticle

Quality of Life
Gastrointestinal Diseases
Eosinophilic enteropathy
Stomach
Small Intestine
8 Citations (Scopus)

New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting

Spergel, J. M., Aceves, S. S., Kliewer, K., Gonsalves, N. P., Chehade, M., Wechsler, J. B., Groetch, M., Friedlander, J., Dellon, E. S., Book, W., Hirano, I., Muir, A. B., Cianferoni, A., Spencer, L., Liacouras, C. A., Cheng, E., Kottyan, L., Wen, T., Platts-Mills, T. & Rothenberg, M. E., Jul 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 48-53 6 p.

Research output: Contribution to journalArticle

Gastrointestinal Diseases
Allergy and Immunology
Hypersensitivity
Asthma
Eosinophils
1 Citation (Scopus)

Oral delivery of fluticasone powder improves esophageal eosinophilic inflammation and symptoms in adults with eosinophilic esophagitis

Kia, L., Nelson, M., Zalewski, A., Gregory, D., Gonsalves, N., Straumann, A. & Hirano, I., Oct 30 2018, In : Diseases of the Esophagus. 31, 12, doy098.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Powders
Steroids
Inflammation
Nebulizers and Vaporizers
5 Citations (Scopus)

Prospective assessment of disease-specific quality of life in adults with eosinophilic esophagitis

Stern, E., Taft, T., Zalewski, A., Gonsalves, N. & Hirano, I., Apr 1 2018, In : Diseases of the Esophagus. 31, 4, dox128.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Quality of Life
Endoscopy
Proton Pumps
Symptom Assessment
90 Citations (Scopus)

Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference

Dellon, E. S., Liacouras, C. A., Molina-Infante, J., Furuta, G. T., Spergel, J. M., Zevit, N., Spechler, S. J., Attwood, S. E., Straumann, A., Aceves, S. S., Alexander, J. A., Atkins, D., Arva, N. C., Blanchard, C., Bonis, P. A., Book, W. M., Capocelli, K. E., Chehade, M., Cheng, E., Collins, M. H. & 46 others, Davis, C. M., Dias, J. A., Di Lorenzo, C., Dohil, R., Dupont, C., Falk, G. W., Ferreira, C. T., Fox, A., Gonsalves, N. P., Gupta, S. K., Katzka, D. A., Kinoshita, Y., Menard-Katcher, C., Kodroff, E., Metz, D. C., Miehlke, S., Muir, A. B., Mukkada, V. A., Murch, S., Nurko, S., Ohtsuka, Y., Orel, R., Papadopoulou, A., Peterson, K. A., Philpott, H., Putnam, P. E., Richter, J. E., Rosen, R., Rothenberg, M. E., Schoepfer, A., Scott, M. M., Shah, N., Sheikh, J., Souza, R. F., Strobel, M. J., Talley, N. J., Vaezi, M. F., Vandenplas, Y., Vieira, M. C., Walker, M. M., Wechsler, J. B., Wershil, B. K., Wen, T., Yang, G-Y., Hirano, I. & Bredenoord, A. J., Oct 2018, In : Gastroenterology. 155, 4, p. 1022-1033.e10

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Proton Pump Inhibitors
Consensus
Eosinophilia
Eosinophils
2017
20 Citations (Scopus)
Eosinophilic Esophagitis
Diet Therapy
Eosinophils
Proton Pump Inhibitors
Dilatation
2016
17 Citations (Scopus)
Eosinophilic Esophagitis
Software
Endoscopy
Catheters
Equipment and Supplies
37 Citations (Scopus)

Evaluation of Esophageal Motility Utilizing the Functional Lumen Imaging Probe

Carlson, D. A., Kahrilas, P. J., Lin, Z., Hirano, I., Gonsalves, N., Listernick, Z., Ritter, K., Tye, M., Ponds, F. A., Wong, I. & Pandolfino, J. E., Dec 1 2016, In : American Journal of Gastroenterology. 111, 12, p. 1726-1735 10 p.

Research output: Contribution to journalArticle

Manometry
Esophagogastric Junction
Esophageal Achalasia
Deglutition Disorders
Esophageal Motility Disorders
6 Citations (Scopus)

Prospective assessment of the diagnostic utility of esophageal brushings in adults with eosinophilic esophagitis

Kern, E., Lin, D., Larson, A., Yang, G. Y., Taft, T., Zalewski, A., Gonsalves, N. & Hirano, I., Jan 1 2016, In : Diseases of the Esophagus. 29, 1, p. 48-53 6 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Cell Biology
Eosinophils
Eosinophilia
Esophagus
26 Citations (Scopus)
Eosinophilic Esophagitis
Eosinophils
Exudates and Transudates
Gastrointestinal Endoscopy
Eosinophilia
14 Citations (Scopus)

Should wheat, barley, rye, and/or gluten be avoided in a 6-food elimination diet?

Kliewer, K. L., Venter, C., Cassin, A. M., Abonia, J. P., Aceves, S. S., Bonis, P. A., Dellon, E. S., Falk, G. W., Furuta, G. T., Gonsalves, N., Gupta, S. K., Hirano, I., Kagalwalla, A., Leung, J., Mukkada, V. A., Spergel, J. M. & Rothenberg, M. E., Apr 1 2016, In : Journal of Allergy and Clinical Immunology. 137, 4, p. 1011-1014 4 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Glutens
Hordeum
Triticum
Diet
92 Citations (Scopus)

Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults with Eosinophilic Esophagitis

Safroneeva, E., Straumann, A., Coslovsky, M., Zwahlen, M., Kuehni, C. E., Panczak, R., Haas, N. A., Alexander, J. A., Dellon, E. S., Gonsalves, N., Hirano, I., Leung, J., Bussmann, C., Collins, M. H., Newbury, R. O., De Petris, G., Smyrk, T. C., Woosley, J. T., Yan, P., Yang, G. Y. & 8 others, Romero, Y., Katzka, D. A., Furuta, G. T., Gupta, S. K., Aceves, S. S., Chehade, M., Spergel, J. M. & Schoepfer, A. M., Mar 1 2016, In : Gastroenterology. 150, 3, p. 581-590.e4

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Eosinophils
Digestive System Endoscopy
Exudates and Transudates
Switzerland
2015
2 Citations (Scopus)

Dysregulation of the Wnt pathway in adult eosinophilic esophagitis

Giannetti, M., Schroeder, H. A., Zalewski, A., Gonsalves, N. P. & Bryce, P. J., Nov 1 2015, In : Diseases of the Esophagus. 28, 8, p. 705-710 6 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Wnt Signaling Pathway
Cyclin D1
Biopsy
Eosinophils
36 Citations (Scopus)

Eosinophilic oesophagitis: Relationship of quality of life with clinical, endoscopic and histological activity

Safroneeva, E., Coslovsky, M., Kuehni, C. E., Zwahlen, M., Haas, N. A., Panczak, R., Taft, T. H., Hirano, I., Dellon, E. S., Gonsalves, N., Leung, J., Bussmann, C., Woosley, J. T., Yan, P., Romero, Y., Furuta, G. T., Gupta, S. K., Aceves, S. S., Chehade, M., Straumann, A. & 1 others, Schoepfer, A. M., Oct 1 2015, In : Alimentary Pharmacology and Therapeutics. 42, 8, p. 1000-1010 11 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Quality of Life
Digestive System Endoscopy
Nonparametric Statistics
58 Citations (Scopus)

Esophageal microbiome in eosinophilic esophagitis

Harris, J. K., Fang, R., Wagner, B. D., Choe, H. N., Kelly, C. J., Schroeder, S., Moore, W., Stevens, M. J., Yeckes, A., Amsden, K., Kagalwalla, A. F., Zalewski, A., Hirano, I., Gonsalves, N., Henry, L. N., Masterson, J. C., Robertson, C. E., Leung, D. Y., Pace, N. R., Ackerman, S. J. & 2 others, Furuta, G. T. & Fillon, S. A., May 28 2015, In : PloS one. 10, 5, e0128346.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
esophageal diseases
Microbiota
gastroesophageal reflux
Gastroesophageal Reflux
29 Citations (Scopus)

How do gastroenterologists assess overall activity of eosinophilic esophagitis in adult patients?

Schoepfer, A. M., Panczak, R., Zwahlen, M., Kuehni, C. E., Coslovsky, M., Maurer, E., Haas, N. A., Alexander, J. A., Dellon, E. S., Gonsalves, N., Hirano, I., Leung, J., Bussmann, C., Collins, M. H., Newbury, R. O., De Petris, G., Smyrk, T. C., Woosley, J. T., Yan, P., Yang, G. Y. & 9 others, Romero, Y., Katzka, D. A., Furuta, G. T., Gupta, S. K., Aceves, S. S., Chehade, M., Blanchard, C., Straumann, A. & Safroneeva, E., Mar 10 2015, In : American Journal of Gastroenterology. 110, 3, p. 402-414 13 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Gastroenterologists
Digestive System Endoscopy
Physicians
Linear Models
48 Citations (Scopus)

Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease

Pothoven, K. L., Norton, J. E., Hulse, K. E., Suh, L. A., Carter, R. G., Rocci, E., Harris, K. E., Shintani-Smith, S., Conley, D. B., Chandra, R. K., Liu, M. C., Kato, A., Gonsalves, N., Grammer, L. C., Peters, A. T., Kern, R. C., Bryce, P. J., Tan, B. K. & Schleimer, R. P., Sep 1 2015, In : Journal of Allergy and Clinical Immunology. 136, 3, p. 737-746.e4

Research output: Contribution to journalArticle

Oncostatin M
Epithelial Cells
Eosinophilic Esophagitis
Nasal Polyps
Bronchoalveolar Lavage Fluid
2014
103 Citations (Scopus)

Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis

Schoepfer, A. M., Straumann, A., Panczak, R., Coslovsky, M., Kuehni, C. E., Maurer, E., Haas, N. A., Romero, Y., Hirano, I., Alexander, J. A., Gonsalves, N., Furuta, G. T., Dellon, E. S., Leung, J., Collins, M. H., Bussmann, C., Netzer, P., Gupta, S. K., Aceves, S. S., Chehade, M. & 30 others, Moawad, F. J., Enders, F. T., Yost, K. J., Taft, T. H., Kern, E., Zwahlen, M., Safroneeva, E., Achem, S. R., Arora, A. S., Alpan, O., Armstrong, D., Attwood, S. E., Butterfield, J. H., Crowell, M. D., De Petris, G., DeVault, K. R., Drouin, E., Enav, B., Fleischer, D. E., Foxx-Orenstein, A., Francis, D. L., Guyatt, G. H., Harris, L. A., Kagalwalla, A. F., Katzka, D. A., Kita, H., Krishna, M., Lee, J. J., Lewis, J. C. & Lim, K., Dec 1 2014, In : Gastroenterology. 147, 6, p. 1255-1266.e21

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Deglutition Disorders
Validation Studies
Deglutition
Focus Groups
14 Citations (Scopus)
Eosinophilic Esophagitis
Esophageal Diseases
Food
Exudates and Transudates
Genetic Predisposition to Disease
95 Citations (Scopus)

GWAS identifies four novel eosinophilic esophagitis loci

Sleiman, P. M. A., Wang, M. L., Cianferoni, A., Aceves, S., Gonsalves, N., Nadeau, K., Bredenoord, A. J., Furuta, G. T., Spergel, J. M. & Hakonarson, H., 2014, In : Nature communications. 5, 5593.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Genome-Wide Association Study
loci
esophagus
Calpain
2013
588 Citations (Scopus)

ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE)

Dellon, E. S., Gonsalves, N. P., Hirano, I., Furuta, G. T., Liacouras, C. A. & Katzka, D. A., May 1 2013, In : American Journal of Gastroenterology. 108, 5, p. 679-692 14 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Eosinophilia
Guidelines
Proton Pump Inhibitors
Terminology
277 Citations (Scopus)

Endoscopic assessment of the oesophageal features of eosinophilic oesophagitis: Validation of a novel classification and grading system

Hirano, I., Moy, N., Heckman, M. G., Thomas, C. S., Gonsalves, N. & Achem, S. R., Apr 1 2013, In : Gut. 62, 4, p. 489-495 7 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Esophagus
Felidae
Edema
Exudates and Transudates
136 Citations (Scopus)

Esophageal Distensibility as a Measure of Disease Severity in Patients With Eosinophilic Esophagitis

Nicodème, F., Hirano, I., Chen, J., Robinson, K., Lin, Z., Xiao, Y., Gonsalves, N., Kwasny, M. J., Kahrilas, P. J. & Pandolfino, J. E., Sep 2013, In : Clinical Gastroenterology and Hepatology. 11, 9, p. 1101-1107.e1

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Dilatation
Food
Eosinophilia
Electric Impedance
35 Citations (Scopus)
Eosinophilic Esophagitis
Endoscopy
Pathologic Constriction
Phenotype
Pressure
2012
368 Citations (Scopus)
Eosinophilic Esophagitis
Eosinophils
Diet
Food
Digestive System Endoscopy
2011
48 Citations (Scopus)
Androstadienes
Eosinophilic Esophagitis
Carboxypeptidases A
CC Chemokines
Mast Cells
81 Citations (Scopus)

Manometric features of eosinophilic esophagitis in esophageal pressure topography

Roman, S., Hirano, I., Kwiatek, M. A., Gonsalves, N., Chen, J., Kahrilas, P. J. & Pandolfino, J. E., Mar 1 2011, In : Neurogastroenterology and Motility. 23, 3, p. 208-e111

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Pressure
Gastroesophageal Reflux
Peristalsis
Deglutition
2010
199 Citations (Scopus)

Esophageal dilation in eosinophilic esophagitis: Effectiveness, safety, and impact on the underlying inflammation

Schoepfer, A. M., Gonsalves, N. P., Bussmann, C., Conus, S., Simon, H. U., Straumann, A. & Hirano, I., May 1 2010, In : American Journal of Gastroenterology. 105, 5, p. 1062-1070 9 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Dilatation
Inflammation
Safety
Deglutition Disorders
2009
131 Citations (Scopus)

Histopathologic variability in children with eosinophilic esophagitis

Shah, A., Kagalwalla, A. F., Gonsalves, N., Melin-Aldana, H., Li, B. U. K. & Hirano, I., Mar 1 2009, In : American Journal of Gastroenterology. 104, 3, p. 716-721 6 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Biopsy
Eosinophils
Eosinophilia
Acids
2008
23 Citations (Scopus)
Proton Pump Inhibitors
Acids
Therapeutics
Rabeprazole
Esophageal pH Monitoring
2007
3 Citations (Scopus)
tetrachloroisophthalonitrile
Omeprazole
Therapeutics
2006
330 Citations (Scopus)

Histopathologic variability and endoscopic correlates in adults with eosinophilic esophagitis

Gonsalves, N. P., Policarpio-Nicolas, M., Zhang, Q., Musunuri, S. R. & Hirano, I., Sep 1 2006, In : Gastrointestinal endoscopy. 64, 3, p. 313-319 7 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Biopsy
Eosinophils
Eosinophilia
Deglutition Disorders