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Olga Frankfurt

  • 1714 Citations
19992023

Research output per year

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Personal profile

Certifications and Licenses

Internal Medicine
Medical Oncology
Hematology

Training Experience

2002Residency, Rush University Medical Center
2005Fellowship, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)

Education/Academic qualification

MD, The University of Chicago

… → 1999

Research interests

  • Acute Leukemias
  • Aplastic Anemia
  • Bone Marrow Transplantation
  • Chronic Leukemias
  • Cord Stem Cell Transplant
  • Hematological Malignancies
  • Leukemia
  • Myelodysplastic Syndrome

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Grants

Prot #AML003: Phase III Multicenter Open-Label Randomized Trial to Evaluate Efficacy and Safety of CPI-613 in Combination With High Dose Cytarabine and Mitoxantrone (CHAM) Compared to High Dose Cytarabine and Mitoxantrone (HAM) in Older Patients (≥60 Year

Frankfurt, O.

Novella Clinical, LLC, Rafael Pharmaceuticals, Inc.

5/1/19 → 5/1/22

Project: Research project

Prot #APL2-302: A Phase III Randomized, Multi-Center, Open-Label, Active-Comparator Controlled Study to Evaluate the Efficacy and Safety of APL-2 in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Frankfurt, O.

Biorasi, LLC, Apellis Pharmaceuticals, Inc.

1/30/19 → 1/30/22

Project: Research project

Prot #GC P#05.01.020: A Multicenter, Randomized, Phase III Registration Trial of Transplantation of NiCord®, Ex Vivo Expanded, Umbilical Cord Blood-derived, Stem and Progenitor Cells, versus Unmanipulated Umbilical Cord Blood for Patients with Hematologic

Frankfurt, O.

Gamida Cell Ltd.

1/15/19 → 1/15/22

Project: Research project

Prot #INCB18424-MA-GD-301: An Open-Label, Expanded Access Program of Ruxolitinib for the Treatment of Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplant

Frankfurt, O.

PAREXEL International Corporation, Incyte Corporation

11/28/18 → 11/28/21

Project: Research project

Prot #BST002: A Phase 2b, Open-Label, Single Arm, Multi-Center Study to Assess the Efficacy and Safety of BST-236 as a Single Agent in Adults with Newly-Diagnosed Acute Myeloid Leukemia, Not Eligible for Standard Induction Therapy

Frankfurt, O.

PRA Health Sciences, BioSight Ltd.

10/29/18 → 10/29/21

Project: Research project

Research Output

An integrative approach reveals genetic complexity and epigenetic perturbation in acute promyelocytic leukemia: a single institution experience

Rahimi, N., Zhang, Y., Mina, A., Altman, J. K., Sukhanova, M., Frankfurt, O., Jennings, L., Lu, X., Behdad, A., Chen, Q., Chen, Y. H. & Gao, J., Sep 2019, In : Human pathology. 91, p. 1-10 10 p.

Research output: Contribution to journal › Article

    • 2 Scopus citations

    Aurora kinase A inhibition provides clinical benefit, normalizes megakaryocytes, and reduces bone marrow fibrosis in patients with myelofibrosis: A phase I trial

    Gangat, N., Marinaccio, C., Swords, R., Watts, J. M., Gurbuxani, S., Rademaker, A., Fought, A. J., Frankfurt, O., Altman, J. K., Wen, Q. J., Farnoud, N., Famulare, C. A., Patel, A., Tapia, R., Vallapureddy, R. R., Barath, S., Graf, A., Handlogten, A., Zblewski, D., Patnaik, M. M. & 14 others, Al-Kali, A., Dinh, Y. T., Prahl, K. E., Patel, S., Nobrega, J. C., Tejera, D., Thomassen, A., Gao, J., Ji, P., Rampal, R. K., Giles, F. J., Tefferi, A., Stein, B. & Crispino, J. D., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4898-4906 9 p.

    Research output: Contribution to journal › Article

    • 12 Scopus citations

    Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

    Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. DI., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., Jan 1 2019, In : Blood. 133, 11, p. 1171-1185 15 p.

    Research output: Contribution to journal › Article

    • 5 Scopus citations

    Patterns of Failure and Survival Outcomes after Total Lymphoid Irradiation and High-Dose Chemotherapy with Autologous Stem Cell Transplantation for Relapsed or Refractory Classical Hodgkin Lymphoma

    Paudel, N., Schulze, D., Gentzler, R. D., Evens, A. M., Helenowski, I., Dillehay, G., Frankfurt, O., Mehta, J., Donnelly, E. D., Gordon, L. I., Winter, J. N. & Mittal, B. B., Jun 1 2019, In : International Journal of Radiation Oncology Biology Physics. 104, 2, p. 436-446 11 p.

    Research output: Contribution to journal › Article

    • Pentostatin, Cyclophosphamide, and Rituximab Followed by Alemtuzumab for Relapsed or Refractory Chronic Lymphocytic Leukemia: A Phase 2 Trial of the ECOG-Acrin Cancer Research Group (E2903)

    Kempin, S., Sun, Z., Kay, N. E., Paietta, E. M., Mazza, J. J., Ketterling, R. P., Frankfurt, O., Claxton, D. F., Saltzman, J. N., Srkalovic, G., Callander, N. S., Gross, G. & Tallman, M. S., Nov 1 2019, In : Acta Haematologica. 142, 4, p. 224-232 9 p.

    Research output: Contribution to journal › Article