Olga Frankfurt

  • 1923 Citations
19992020

Research output per year

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Research Output

2020

A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/ refractory FLT3-ITD–mutant acute myeloid leukemia

Smith, C. C., Levis, M. J., Frankfurt, O., Pagel, J. M., Roboz, G. J., Stone, R. M., Wang, E. S., Severson, P. L., West, B. L., Le, M. H., Kayser, S., Lam, B., Hsu, H. H., Zhang, C., Bollag, G. & Perl, A. E., Apr 28 2020, In : Blood Advances. 4, 8, p. 1711-1721 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019
3 Scopus citations

Aurora kinase A inhibition provides clinical benefit, normalizes megakaryocytes, and reduces bone marrow fibrosis in patients with myelofibrosis: A phase I trial

Gangat, N., Marinaccio, C., Swords, R., Watts, J. M., Gurbuxani, S., Rademaker, A., Fought, A. J., Frankfurt, O., Altman, J. K., Wen, Q. J., Farnoud, N., Famulare, C. A., Patel, A., Tapia, R., Vallapureddy, R. R., Barath, S., Graf, A., Handlogten, A., Zblewski, D., Patnaik, M. M. & 14 others, Al-Kali, A., Dinh, Y. T., Prahl, K. E., Patel, S., Nobrega, J. C., Tejera, D., Thomassen, A., Gao, J., Ji, P., Rampal, R. K., Giles, F. J., Tefferi, A., Stein, B. & Crispino, J. D., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4898-4906 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. DI., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., Jan 1 2019, In : Blood. 133, 11, p. 1171-1185 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pentostatin, Cyclophosphamide, and Rituximab Followed by Alemtuzumab for Relapsed or Refractory Chronic Lymphocytic Leukemia: A Phase 2 Trial of the ECOG-Acrin Cancer Research Group (E2903)

Kempin, S., Sun, Z., Kay, N. E., Paietta, E. M., Mazza, J. J., Ketterling, R. P., Frankfurt, O., Claxton, D. F., Saltzman, J. N., Srkalovic, G., Callander, N. S., Gross, G. & Tallman, M. S., Nov 1 2019, In : Acta Haematologica. 142, 4, p. 224-232 9 p.

Research output: Contribution to journalArticle

Rare myeloid sarcoma with KMT2A (MLL)-ELL fusion presenting as a vaginal wall mass

Bao, H., Gao, J., Chen, Y. H., Altman, J. K., Frankfurt, O., Wilson, A. L., Sukhanova, M., Chen, Q. & Lu, X., Mar 28 2019, In : Diagnostic pathology. 14, 1, 26.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The utility of a telemedicine platform to monitor adherence and adverse effects of tyrosine kinase inhibitors

Copeland, A. C., Foster, M. C., Muluneh, B., Xenakis, J. G., Ivanova, A., Frankfurt, O., Clayton, M., Black, A., Rapchak, B. & Wehbie, R. S., Jun 7 2019, In : Leukemia and Lymphoma. 60, 7, p. 1842-1844 3 p.

Research output: Contribution to journalLetter

Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia

DiNardo, C. D., Pratz, K., Pullarkat, V., Jonas, B. A., Arellano, M., Becker, P. S., Frankfurt, O., Konopleva, M., Wei, A. H., Kantarjian, H. M., Xu, T., Hong, W. J., Chyla, B., Potluri, J., Pollyea, D. A. & Letai, A., Jan 3 2019, In : Blood. 133, 1, p. 7-17 11 p.

Research output: Contribution to journalArticle

315 Scopus citations
2018

Blinatumomab and pancreatitis: an analysis of FAERS, EudraVigilance, and a large urban U.S. patient population data

Vakharia, P., Nardone, B., Budris, W., Hoshizaki, K., Frankfurt, O. & West, D. P., Jul 3 2018, In : Leukemia and Lymphoma. 59, 7, p. 1759-1761 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Results of a phase 1 study of quizartinib as maintenance therapy in subjects with acute myeloid leukemia in remission following allogeneic hematopoietic stem cell transplant

Sandmaier, B. M., Khaled, S., Oran, B., Gammon, G., Trone, D. & Frankfurt, O., Feb 1 2018, In : American Journal of Hematology. 93, 2, p. 222-231 10 p.

Research output: Contribution to journalArticle

35 Scopus citations
2017

Disease characteristics and prognosis of myelodysplastic syndrome presenting with isolated thrombocytopenia

Waisbren, J., Dinner, S., Altman, J., Frankfurt, O., Helenowski, I., Gao, J., McMahon, B. J. & Stein, B. L., Jan 1 2017, In : International journal of hematology. 105, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
14 Scopus citations

Myelodysplastic syndromes, version 2.2017: Clinical practice guidelines in oncology

Greenberg, P. L., Stone, R. M., Al-Kali, A., Barta, S. K., Bejar, R., Bennett, J. M., Carraway, H., De Castro, C. M., Deeg, H. J., DeZern, A. E., Fathi, A. T., Frankfurt, O., Gaensler, K., Garcia-Manero, G., Griffiths, E. A., Head, D., Horsfall, R., Johnson, R. A., Juckett, M., Klimek, V. M. & 12 others, Komrokji, R., Kujawski, L. A., Maness, L. J., O'Donnell, M. R., Pollyea, D. A., Shami, P. J., Stein, B. L., Walker, A. R., Westervelt, P., Zeidan, A., Shead, D. A. & Smith, C., Jan 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 1, p. 60-87 28 p.

Research output: Contribution to journalReview article

122 Scopus citations

NCCN Guidelines® insights acute lymphoblastic Leukemia, Version 1.2017 featured updates to the NCCN guidelines

Brown, P. A., Shah, B., Fathi, A., Wieduwilt, M., Advani, A., Aoun, P., Barta, S. K., Boyer, M. W., Bryan, T., Burke, P. W., Cassaday, R., Coccia, P. F., Coutre, S. E., Damon, L. E., DeAngelo, D. J., Frankfurt, O., Greer, J. P., Kantarjian, H. M., Klisovic, R. B., Kupfer, G. & 10 others, Litzow, M., Liu, A., Mattison, R., Park, J., Rubnitz, J., Saad, A., Uy, G. L., Wang, E. S., Gregory, K. M. & Ogba, N., Sep 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 9, p. 1091-1102 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Acute lymphoblastic leukemia, version 2.2015: Clinical practice guidelines in oncology

Alvarnas, J. C., Brown, P. A., Aoun, P., Ballen, K. K., Barta, S. K., Borate, U., Boyer, M. W., Burke, P. W., Cassaday, R., Castro, J. E., Coccia, P. F., Coutre, S. E., Damon, L. E., De Angelo, D. J., Douer, D., Frankfurt, O., Greer, J. P., Johnson, R. A., Kantarjian, H. M., Klisovic, R. B. & 10 others, Kupfer, G., Litzow, M., Liu, A., Rao, A. V., Shah, B., Uy, G. L., Wang, E. S., Zelenetz, A. D., Gregory, K. & Smith, C., Oct 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 10, p. 1240-1279 40 p.

Research output: Contribution to journalReview article

51 Scopus citations

Adverse events during hematopoietic stem cell infusion: Analysis of the infusion product

Vidula, N., Villa, M., Helenowski, I. B., Merchant, M., Jovanovic, B. D., Meagher, R., Mehta, J., Singhal, S., Winter, J. N., Frankfurt, O., Altman, J. K., Williams, S. F. & Gordon, L. I., Nov 2015, In : Clinical Lymphoma, Myeloma and Leukemia. 15, 11, p. e157-e162

Research output: Contribution to journalArticle

4 Scopus citations

Myelodysplastic syndromes, version 2.2015 featured updates to the NCCN guidelines

Greenberg, P. L., Stone, R. M., Bejar, R., Bennett, J. M., Bloomfield, C. D., Borate, U., De Castro, C. M., Deeg, H. J., DeZern, A. E., Fathi, A. T., Frankfurt, O., Gaensler, K., Garcia-Manero, G., Griffiths, E. A., Head, D., Klimek, V., Komrokji, R., Kujawski, L. A., Maness, L. J., O'Donnell, M. R. & 8 others, Pollyea, D. A., Scott, B., Shami, P. J., Stein, B. L., Westervelt, P., Wheeler, B., Shead, D. A. & Smith, C., Mar 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 3, p. 261-272 12 p.

Research output: Contribution to journalReview article

32 Scopus citations
10 Scopus citations
6 Scopus citations
2014

Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients

Frankel, A. E., Woo, J. H., Ahn, C., Pemmaraju, N., Medeiros, B. C., Carraway, H. E., Frankfurt, O., Forman, S. J., Yang, X. A., Konopleva, M., Garnache-Ottou, F., Angelot-Delettre, F., Brooks, C., Szarek, M. & Rowinsky, E., Jul 17 2014, In : Blood. 124, 3, p. 385-392 8 p.

Research output: Contribution to journalArticle

132 Scopus citations
2 Scopus citations

Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting

Altman, J. K., Szilard, A., Goussetis, D. J., Sassano, A., Colamonici, M., Gounaris, E., Frankfurt, O., Giles, F. J., Eklund, E. A., Beauchamp, E. M. & Platanias, L. C., May 1 2014, In : Clinical Cancer Research. 20, 9, p. 2400-2409 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

F-18 FDG-PET predicts outcomes for patients receiving total lymphoid irradiation and autologous blood stem-cell transplantation for relapsed and refractory Hodgkin lymphoma

Gentzler, R. D., Evens, A. M., Rademaker, A. W., Weitner, B. B., Mittal, B. B., Dillehay, G. L., Petrich, A. M., Altman, J. K., Frankfurt, O., Variakojis, D., Singhal, S., Mehta, J., Williams, S., Kaminer, L., Gordon, L. I. & Winter, J. N., Jun 2014, In : British Journal of Haematology. 165, 6, p. 793-800 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Heritable GATA2 mutations associated with familial AML-MDS: A case report and review of literature

Gao, J., Gentzler, R. D., Timms, A. E., Horwitz, M. S., Frankfurt, O., Altman, J. K. & Peterson, L. C., Apr 22 2014, In : Journal of Hematology and Oncology. 7, 1, 36.

Research output: Contribution to journalReview article

18 Scopus citations

The impact of symptom burden on patient quality of life in chronic myeloid leukemia

Cella, D., Nowinski, C. J. & Frankfurt, O., Jan 1 2014, In : Oncology (Switzerland). 87, 3, p. 133-147 15 p.

Research output: Contribution to journalReview article

14 Scopus citations
7 Scopus citations
2013

Administration of ATRA to newly diagnosed patients with acute promyelocytic leukemia is delayed contributing to early hemorrhagic death

Altman, J. K., Rademaker, A., Cull, E., Weitner, B. B., Ofran, Y., Rosenblat, T. L., Haidau, A., Park, J. H., Ram, S. L., Orsini, J. M., Sandhu, S., Catchatourian, R., Trifilio, S. M., Adel, N. G., Frankfurt, O., Stein, E. M., Mallios, G., Deblasio, T., Jurcic, J. G., Nimer, S. & 5 others, Peterson, L. A. C., Kwaan, H. C., Rowe, J. M., Douer, D. & Tallman, M. S., Sep 1 2013, In : Leukemia Research. 37, 9, p. 1004-1009 6 p.

Research output: Contribution to journalArticle

56 Scopus citations

Demodex folliculitis mimicking acute graft-vs-host disease

Cotliar, J. & Frankfurt, O., Dec 1 2013, In : JAMA dermatology. 149, 12, p. 1407-1409 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
7 Scopus citations

Implications of lipocalin 2 expression in acute myeloid leukemia

Frankfurt, O. & Platanias, L. C., Aug 2013, In : Leukemia and Lymphoma. 54, 8, p. 1573-1574 2 p.

Research output: Contribution to journalComment/debate

Myelodysplastic syndromes

Greenberg, P. L., Attar, E., Bennett, J. M., Bloomfield, C. D., Borate, U., De Castro, C. M., Deeg, H. J., Frankfurt, O., Gaensler, K., Garcia-Manero, G., Gore, S. D., Head, D., Komrokji, R., Maness, L. J., Millenson, M., O'Donnell, M. R., Shami, P. J., Stein, B. L., Stone, R. M., Thompson, J. E. & 4 others, Westervelt, P., Wheeler, B., Shead, D. A. & Naganuma, M., Jul 1 2013, In : JNCCN Journal of the National Comprehensive Cancer Network. 11, 7, p. 838-874 37 p.

Research output: Contribution to journalArticle

77 Scopus citations
3 Scopus citations

Ponatinib - A step forward in overcoming resistance in chronic myeloid leukemia

Frankfurt, O. & Licht, J. D., Nov 1 2013, In : Clinical Cancer Research. 19, 21, p. 5828-5834 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
2012

Acute lymphoblastic leukemia: Clinical practice guidelines in oncology

Alvarnas, J. C., Brown, P. A., Aoun, P., Ballen, K. K., Bellam, N., Blum, W., Boyer, M. W., Carraway, H. E., Coccia, P. F., Coutre, S. E., Cultrera, J., Damon, L. E., DeAngelo, D. J., Douer, D., Frangoul, H., Frankfurt, O., Goorha, S., Millenson, M. M., O'Brien, S., Petersdorf, S. H. & 7 others, Rao, A. V., Terezakis, S., Uy, G., Wetzler, M., Zelenetz, A. D., Naganuma, M. & Gregory, K. M., Jul 1 2012, In : JNCCN Journal of the National Comprehensive Cancer Network. 10, 7, p. 858-914 57 p.

Research output: Contribution to journalReview article

41 Scopus citations

Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia

Wendtner, C. M., Hillmen, P., Mahadevan, D., Bhler, A., Uharek, L., Coutré, S., Frankfurt, O., Bloor, A., Bosch, F., Furman, R. R., Kimby, E., Gribben, J. G., Gobbi, M., Dreisbach, L., Hurd, D. D., Sekeres, M. A., Ferrajoli, A., Shah, S., Zhang, J., Moutouh-De Parseval, L. & 4 others, Hallek, M., Heerema, N. A., Stilgenbauer, S. & Chanan-Khan, A. A., Mar 2012, In : Leukemia and Lymphoma. 53, 3, p. 417-423 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Mitoxantrone and etoposide with or without intermediate dose cytarabine for the treatment of primary induction failure or relapsed acute myeloid leukemia

Trifilio, S. M., Rademaker, A. W., Newman, D., Coyle, K., Carlson-Leuer, K., Mehta, J., Altman, J., Frankfurt, O. & Tallman, M. S., Apr 1 2012, In : Leukemia Research. 36, 4, p. 394-396 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Non-tyrosine kinase inhibitor-targeting of BCRABL expressing cells

Frankfurt, O. & Platanias, L. C., Oct 2012, In : Leukemia and Lymphoma. 53, 10, p. 1857-1858 2 p.

Research output: Contribution to journalComment/debate

2011

Management of Emergencies in Leukemias

Frankfurt, O., Jan 4 2011, Leukemias: Principles and Practice of Therapy. Wiley Blackwell, p. 373-391 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The hematopoietic growth factors in acute leukemia: US perspective

Frankfurt, O. & Tallman, M. S., Jan 1 2011, Hematopoietic Growth Factors in Oncology. Lyman, G. & Dale, D. (eds.). p. 307-337 31 p. (Cancer Treatment and Research; vol. 157).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2009

Actual or ideal body weight to calculate CD34+ cell dose in patients undergoing autologous hematopoietic SCT for myeloma?

Singh, V., Krishnamurthy, J., Duffey, S., Meagher, R., Villa, M., Monreal, J., Evens, A., Frankfurt, O., Altman, J. K., Gordon, L. I., Tallman, M., Williams, S., Winter, J. N., Singhal, S. & Mehta, J., Jan 1 2009, In : Bone Marrow Transplantation. 43, 4, p. 301-305 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Optimizing the CD34 + cell dose for reduced-intensity allogeneic hematopoietic stem cell transplantation

Mehta, J., Frankfurt, O., Altman, J., Evens, A., Tallman, M., Gordon, L., Williams, S., Winter, J., Krishnamurthy, J., Duffey, S., Singh, V., Meagher, R., Grinblatt, D., Kaminer, L. & Singhal, S., 2009, In : Leukemia and Lymphoma. 50, 9, p. 1434-1441 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

The coagulopathy of acute promyelocytic leukaemia revisited

Stein, E., McMahon, B., Kwaan, H., Altman, J. K., Frankfurt, O. & Tallman, M. S., Mar 1 2009, In : Best Practice and Research: Clinical Haematology. 22, 1, p. 153-163 11 p.

Research output: Contribution to journalReview article

96 Scopus citations

Treatment of B-cell chronic lymphocytic leukemia with nonchemotherapeutic agents: Experience with single-agent and combination therapy

Faderl, S., Ferrajoli, A., Frankfurt, O. & Pettitt, A., Jan 1 2009, In : Leukemia. 23, 3, p. 457-466 10 p.

Research output: Contribution to journalReview article

14 Scopus citations
2008

A phase II clinical trial of intensive chemotherapy followed by consolidative stem cell transplant: Long-term follow-up in newly diagnosed mantle cell lymphoma

Evens, A. M., Winter, J. N., Hou, N., Nelson, B. P., Rademaker, A. W., Patton, D., Singhal, S., Frankfurt, O., Tallman, M. S., Rosen, S. T., Mehta, J. & Gordon, L. I., Feb 1 2008, In : British Journal of Haematology. 140, 4, p. 385-393 9 p.

Research output: Contribution to journalArticle

40 Scopus citations
2007

Breakthrough fungal infections after allogeneic hematopoietic stem cell transplantation in patients on prophylactic voriconazole

Trifilio, S., Singhal, S., Williams, S., Frankfurt, O., Gordon, L. I., Evens, A., Winter, J. N., Tallman, M., Pi, J. & Mehta, J., Sep 1 2007, In : Bone Marrow Transplantation. 40, 5, p. 451-456 6 p.

Research output: Contribution to journalArticle

170 Scopus citations

Growth factors in leukemia

Frankfurt, O. & Tallman, M. S., Feb 2007, In : JNCCN Journal of the National Comprehensive Cancer Network. 5, 2, p. 203-215 13 p.

Research output: Contribution to journalReview article

15 Scopus citations

Molecular characterization of acute myeloid leukemia and its impact on treatment

Frankfurt, O., Licht, J. D. & Tallman, M. S., Nov 1 2007, In : Current opinion in oncology. 19, 6, p. 635-649 15 p.

Research output: Contribution to journalReview article

24 Scopus citations

Monitoring plasma voriconazole levels may be necessary to avoid subtherapeutic levels in hematopoietic stem cell transplant recipients

Trifilio, S., Pennick, G., Pi, J., Zook, J., Golf, M., Kaniecki, K., Singhal, S., Williams, S., Winter, J., Tallman, M., Gordon, L., Frankfurt, O., Evens, A. & Mehta, J., Apr 15 2007, In : Cancer. 109, 8, p. 1532-1535 4 p.

Research output: Contribution to journalArticle

177 Scopus citations