Olga Frankfurt

  • 1923 Citations
19992020

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Article
2020

A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/ refractory FLT3-ITD–mutant acute myeloid leukemia

Smith, C. C., Levis, M. J., Frankfurt, O., Pagel, J. M., Roboz, G. J., Stone, R. M., Wang, E. S., Severson, P. L., West, B. L., Le, M. H., Kayser, S., Lam, B., Hsu, H. H., Zhang, C., Bollag, G. & Perl, A. E., Apr 28 2020, In : Blood Advances. 4, 8, p. 1711-1721 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019
3 Scopus citations

Aurora kinase A inhibition provides clinical benefit, normalizes megakaryocytes, and reduces bone marrow fibrosis in patients with myelofibrosis: A phase I trial

Gangat, N., Marinaccio, C., Swords, R., Watts, J. M., Gurbuxani, S., Rademaker, A., Fought, A. J., Frankfurt, O., Altman, J. K., Wen, Q. J., Farnoud, N., Famulare, C. A., Patel, A., Tapia, R., Vallapureddy, R. R., Barath, S., Graf, A., Handlogten, A., Zblewski, D., Patnaik, M. M. & 14 others, Al-Kali, A., Dinh, Y. T., Prahl, K. E., Patel, S., Nobrega, J. C., Tejera, D., Thomassen, A., Gao, J., Ji, P., Rampal, R. K., Giles, F. J., Tefferi, A., Stein, B. & Crispino, J. D., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4898-4906 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. DI., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., Jan 1 2019, In : Blood. 133, 11, p. 1171-1185 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pentostatin, Cyclophosphamide, and Rituximab Followed by Alemtuzumab for Relapsed or Refractory Chronic Lymphocytic Leukemia: A Phase 2 Trial of the ECOG-Acrin Cancer Research Group (E2903)

Kempin, S., Sun, Z., Kay, N. E., Paietta, E. M., Mazza, J. J., Ketterling, R. P., Frankfurt, O., Claxton, D. F., Saltzman, J. N., Srkalovic, G., Callander, N. S., Gross, G. & Tallman, M. S., Nov 1 2019, In : Acta Haematologica. 142, 4, p. 224-232 9 p.

Research output: Contribution to journalArticle

Rare myeloid sarcoma with KMT2A (MLL)-ELL fusion presenting as a vaginal wall mass

Bao, H., Gao, J., Chen, Y. H., Altman, J. K., Frankfurt, O., Wilson, A. L., Sukhanova, M., Chen, Q. & Lu, X., Mar 28 2019, In : Diagnostic pathology. 14, 1, 26.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia

DiNardo, C. D., Pratz, K., Pullarkat, V., Jonas, B. A., Arellano, M., Becker, P. S., Frankfurt, O., Konopleva, M., Wei, A. H., Kantarjian, H. M., Xu, T., Hong, W. J., Chyla, B., Potluri, J., Pollyea, D. A. & Letai, A., Jan 3 2019, In : Blood. 133, 1, p. 7-17 11 p.

Research output: Contribution to journalArticle

315 Scopus citations
2018

Results of a phase 1 study of quizartinib as maintenance therapy in subjects with acute myeloid leukemia in remission following allogeneic hematopoietic stem cell transplant

Sandmaier, B. M., Khaled, S., Oran, B., Gammon, G., Trone, D. & Frankfurt, O., Feb 1 2018, In : American Journal of Hematology. 93, 2, p. 222-231 10 p.

Research output: Contribution to journalArticle

35 Scopus citations
2017

Disease characteristics and prognosis of myelodysplastic syndrome presenting with isolated thrombocytopenia

Waisbren, J., Dinner, S., Altman, J., Frankfurt, O., Helenowski, I., Gao, J., McMahon, B. J. & Stein, B. L., Jan 1 2017, In : International journal of hematology. 105, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
14 Scopus citations

NCCN Guidelines® insights acute lymphoblastic Leukemia, Version 1.2017 featured updates to the NCCN guidelines

Brown, P. A., Shah, B., Fathi, A., Wieduwilt, M., Advani, A., Aoun, P., Barta, S. K., Boyer, M. W., Bryan, T., Burke, P. W., Cassaday, R., Coccia, P. F., Coutre, S. E., Damon, L. E., DeAngelo, D. J., Frankfurt, O., Greer, J. P., Kantarjian, H. M., Klisovic, R. B., Kupfer, G. & 10 others, Litzow, M., Liu, A., Mattison, R., Park, J., Rubnitz, J., Saad, A., Uy, G. L., Wang, E. S., Gregory, K. M. & Ogba, N., Sep 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 9, p. 1091-1102 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Adverse events during hematopoietic stem cell infusion: Analysis of the infusion product

Vidula, N., Villa, M., Helenowski, I. B., Merchant, M., Jovanovic, B. D., Meagher, R., Mehta, J., Singhal, S., Winter, J. N., Frankfurt, O., Altman, J. K., Williams, S. F. & Gordon, L. I., Nov 2015, In : Clinical Lymphoma, Myeloma and Leukemia. 15, 11, p. e157-e162

Research output: Contribution to journalArticle

4 Scopus citations
10 Scopus citations
6 Scopus citations
2014

Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients

Frankel, A. E., Woo, J. H., Ahn, C., Pemmaraju, N., Medeiros, B. C., Carraway, H. E., Frankfurt, O., Forman, S. J., Yang, X. A., Konopleva, M., Garnache-Ottou, F., Angelot-Delettre, F., Brooks, C., Szarek, M. & Rowinsky, E., Jul 17 2014, In : Blood. 124, 3, p. 385-392 8 p.

Research output: Contribution to journalArticle

132 Scopus citations

Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting

Altman, J. K., Szilard, A., Goussetis, D. J., Sassano, A., Colamonici, M., Gounaris, E., Frankfurt, O., Giles, F. J., Eklund, E. A., Beauchamp, E. M. & Platanias, L. C., May 1 2014, In : Clinical Cancer Research. 20, 9, p. 2400-2409 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

F-18 FDG-PET predicts outcomes for patients receiving total lymphoid irradiation and autologous blood stem-cell transplantation for relapsed and refractory Hodgkin lymphoma

Gentzler, R. D., Evens, A. M., Rademaker, A. W., Weitner, B. B., Mittal, B. B., Dillehay, G. L., Petrich, A. M., Altman, J. K., Frankfurt, O., Variakojis, D., Singhal, S., Mehta, J., Williams, S., Kaminer, L., Gordon, L. I. & Winter, J. N., Jun 2014, In : British Journal of Haematology. 165, 6, p. 793-800 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
7 Scopus citations
2013

Administration of ATRA to newly diagnosed patients with acute promyelocytic leukemia is delayed contributing to early hemorrhagic death

Altman, J. K., Rademaker, A., Cull, E., Weitner, B. B., Ofran, Y., Rosenblat, T. L., Haidau, A., Park, J. H., Ram, S. L., Orsini, J. M., Sandhu, S., Catchatourian, R., Trifilio, S. M., Adel, N. G., Frankfurt, O., Stein, E. M., Mallios, G., Deblasio, T., Jurcic, J. G., Nimer, S. & 5 others, Peterson, L. A. C., Kwaan, H. C., Rowe, J. M., Douer, D. & Tallman, M. S., Sep 1 2013, In : Leukemia Research. 37, 9, p. 1004-1009 6 p.

Research output: Contribution to journalArticle

56 Scopus citations

Demodex folliculitis mimicking acute graft-vs-host disease

Cotliar, J. & Frankfurt, O., Dec 1 2013, In : JAMA dermatology. 149, 12, p. 1407-1409 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
7 Scopus citations

Myelodysplastic syndromes

Greenberg, P. L., Attar, E., Bennett, J. M., Bloomfield, C. D., Borate, U., De Castro, C. M., Deeg, H. J., Frankfurt, O., Gaensler, K., Garcia-Manero, G., Gore, S. D., Head, D., Komrokji, R., Maness, L. J., Millenson, M., O'Donnell, M. R., Shami, P. J., Stein, B. L., Stone, R. M., Thompson, J. E. & 4 others, Westervelt, P., Wheeler, B., Shead, D. A. & Naganuma, M., Jul 1 2013, In : JNCCN Journal of the National Comprehensive Cancer Network. 11, 7, p. 838-874 37 p.

Research output: Contribution to journalArticle

77 Scopus citations

Ponatinib - A step forward in overcoming resistance in chronic myeloid leukemia

Frankfurt, O. & Licht, J. D., Nov 1 2013, In : Clinical Cancer Research. 19, 21, p. 5828-5834 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
2012

Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia

Wendtner, C. M., Hillmen, P., Mahadevan, D., Bhler, A., Uharek, L., Coutré, S., Frankfurt, O., Bloor, A., Bosch, F., Furman, R. R., Kimby, E., Gribben, J. G., Gobbi, M., Dreisbach, L., Hurd, D. D., Sekeres, M. A., Ferrajoli, A., Shah, S., Zhang, J., Moutouh-De Parseval, L. & 4 others, Hallek, M., Heerema, N. A., Stilgenbauer, S. & Chanan-Khan, A. A., Mar 2012, In : Leukemia and Lymphoma. 53, 3, p. 417-423 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Mitoxantrone and etoposide with or without intermediate dose cytarabine for the treatment of primary induction failure or relapsed acute myeloid leukemia

Trifilio, S. M., Rademaker, A. W., Newman, D., Coyle, K., Carlson-Leuer, K., Mehta, J., Altman, J., Frankfurt, O. & Tallman, M. S., Apr 1 2012, In : Leukemia Research. 36, 4, p. 394-396 3 p.

Research output: Contribution to journalArticle

16 Scopus citations
2009

Actual or ideal body weight to calculate CD34+ cell dose in patients undergoing autologous hematopoietic SCT for myeloma?

Singh, V., Krishnamurthy, J., Duffey, S., Meagher, R., Villa, M., Monreal, J., Evens, A., Frankfurt, O., Altman, J. K., Gordon, L. I., Tallman, M., Williams, S., Winter, J. N., Singhal, S. & Mehta, J., Jan 1 2009, In : Bone Marrow Transplantation. 43, 4, p. 301-305 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Optimizing the CD34 + cell dose for reduced-intensity allogeneic hematopoietic stem cell transplantation

Mehta, J., Frankfurt, O., Altman, J., Evens, A., Tallman, M., Gordon, L., Williams, S., Winter, J., Krishnamurthy, J., Duffey, S., Singh, V., Meagher, R., Grinblatt, D., Kaminer, L. & Singhal, S., 2009, In : Leukemia and Lymphoma. 50, 9, p. 1434-1441 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2008

A phase II clinical trial of intensive chemotherapy followed by consolidative stem cell transplant: Long-term follow-up in newly diagnosed mantle cell lymphoma

Evens, A. M., Winter, J. N., Hou, N., Nelson, B. P., Rademaker, A. W., Patton, D., Singhal, S., Frankfurt, O., Tallman, M. S., Rosen, S. T., Mehta, J. & Gordon, L. I., Feb 1 2008, In : British Journal of Haematology. 140, 4, p. 385-393 9 p.

Research output: Contribution to journalArticle

40 Scopus citations
2007

Breakthrough fungal infections after allogeneic hematopoietic stem cell transplantation in patients on prophylactic voriconazole

Trifilio, S., Singhal, S., Williams, S., Frankfurt, O., Gordon, L. I., Evens, A., Winter, J. N., Tallman, M., Pi, J. & Mehta, J., Sep 1 2007, In : Bone Marrow Transplantation. 40, 5, p. 451-456 6 p.

Research output: Contribution to journalArticle

170 Scopus citations

Monitoring plasma voriconazole levels may be necessary to avoid subtherapeutic levels in hematopoietic stem cell transplant recipients

Trifilio, S., Pennick, G., Pi, J., Zook, J., Golf, M., Kaniecki, K., Singhal, S., Williams, S., Winter, J., Tallman, M., Gordon, L., Frankfurt, O., Evens, A. & Mehta, J., Apr 15 2007, In : Cancer. 109, 8, p. 1532-1535 4 p.

Research output: Contribution to journalArticle

177 Scopus citations
2006

Does younger donor age affect the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies beneficially?

Mehta, J., Gordon, L. I., Tallman, M. S., Winter, J. N., Evens, A. O., Frankfurt, O., Williams, S. F., Grinblatt, D., Kaminer, L., Meagher, R. & Singhal, S., Jul 2 2006, In : Bone Marrow Transplantation. 38, 2, p. 95-100 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Gradual hearing loss with bilateral labyrinthine hemorrhage in chronic myelogenous leukemia

Cherchi, M., Huo, E., Nelson, N., Frankfurt, O., Russell, E. J. & Raizer, J. J., Jul 1 2006, In : Neurology. 67, 1, p. 177-178 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ideal rather than actual body weight should be used to calculate cell dose in allogeneic hematopoietic stem cell transplantation

Singhal, S., Gordon, L. I., Tallman, M. S., Winter, J. N., Evens, A. O., Frankfurt, O., Williams, S. F., Grinblatt, D., Kaminer, L., Meagher, R. & Mehta, J., Jan 1 2006, In : Bone Marrow Transplantation. 37, 6, p. 553-557 5 p.

Research output: Contribution to journalArticle

13 Scopus citations