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Research Output 1999 2019

2019
8 Citations (Scopus)

ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis

Hoeman, C. M., Cordero, F. J., Hu, G., Misuraca, K., Romero, M. M., Cardona, H. J., Nazarian, J., Hashizume, R., McLendon, R., Yu, P., Procissi, D., Gadd, S. L. & Becher, O. J., Mar 4 2019, In : Nature communications. 10, 1, 1023.

Research output: Contribution to journalArticle

pathogenesis
Glioma
Tumors
tumors
mutations
2 Citations (Scopus)

CDK4/6 and diffuse intrinsic pontine glioma - Evaluate at diagnosis?

Becher, O. J., Jun 1 2019, In : EBioMedicine. 44, p. 16-17 2 p.

Research output: Contribution to journalComment/debate

Open Access
Glioma
1 Citation (Scopus)

Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models

Martinez-Velez, N., Marigil, M., García-Moure, M., Gonzalez-Huarriz, M., Aristu, J. J., Ramos-García, L. I., Tejada, S., Díez-Valle, R., Patiño-García, A., Becher, O. J., Gomez-Manzano, C., Fueyo, J. & Alonso, M. M., Apr 29 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Glioma
Radiotherapy
Pediatrics
Neoplasms
Therapeutics

HDAC inhibitors to the rescue in sonic hedgehog medulloblastoma

Becher, O. J., Sep 6 2019, In : Neuro-oncology. 21, 9, p. 1091-1092 2 p.

Research output: Contribution to journalEditorial

Medulloblastoma
Histone Deacetylase Inhibitors

Identification of novel Ras signaling therapeutic vulnerabilities in diffuse intrinsic pontine gliomas

Koncar, R. F., Dey, B. R., Stanton, A. C. J., Agrawal, N., Wassell, M. L., McCarl, L. H., Locke, A. L., Sanders, L., Morozova-Vaske, O., Myers, M. I., Hamilton, R. L., Carcaboso, A. M., Kohanbash, G., Hu, B., Amankulor, N. M., Felker, J., Kambhampati, M., Nazarian, J., Becher, O. J., James, C. D. & 4 others, Hashizume, R., Broniscer, A., Pollack, I. F. & Agnihotri, S., Aug 15 2019, In : Cancer Research. 79, 16, p. 4026-4041 16 p.

Research output: Contribution to journalArticle

Glioma
Mutation
Therapeutics
Brain Stem Neoplasms
Proto-Oncogenes
2 Citations (Scopus)

Radiosensitization by histone H3 demethylase inhibition in diffuse intrinsic pontine glioma

Katagi, H., Louis, N., Unruh, D., Sasaki, T., He, X., Zhang, A., Ma, Q., Piunti, A., Shimazu, Y., Lamano, J. B., Carcaboso, A. M., Tian, X., Seluanov, A., Gorbunova, V., Laurie, K. L., Kondo, A., Wadhwani, N. R., Lulla, R., Goldman, S., Venneti, S. & 4 others, Becher, O. J., Zou, L., Shilatifard, A. & Hashizume, R., Sep 15 2019, In : Clinical Cancer Research. 25, 18, p. 5572-5583 12 p.

Research output: Contribution to journalArticle

Histone Demethylases
Glioma
Histones
Radiotherapy
Double-Stranded DNA Breaks
1 Citation (Scopus)

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Martínez-Vélez, N., Garcia-Moure, M., Marigil, M., González-Huarriz, M., Puigdelloses, M., Gallego Pérez-Larraya, J., Zalacaín, M., Marrodán, L., Varela-Guruceaga, M., Laspidea, V., Aristu, J. J., Ramos, L. I., Tejada-Solís, S., Díez-Valle, R., Jones, C., Mackay, A., Martínez-Climent, J. A., García-Barchino, M. J., Raabe, E., Monje, M. & 10 others, Becher, O. J., Junier, M. P., El-Habr, E. A., Chneiweiss, H., Aldave, G., Jiang, H., Fueyo, J., Patiño-García, A., Gomez-Manzano, C. & Alonso, M. M., May 28 2019, In : Nature communications. 10, 1, 2235.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
Pediatrics
viruses
Viruses
Glioma
2018
4 Citations (Scopus)

CDK4/6 and PDGFRA signaling as therapeutic targets in diffuse intrinsic pontine glioma

Hoeman, C. M., Shen, C. & Becher, O. J., May 31 2018, In : Frontiers in Oncology. 8, MAY, 191.

Research output: Contribution to journalReview article

Glioma
Gene Transfer Techniques
Manuscripts
Standard of Care
Brain Neoplasms
1 Citation (Scopus)

T2-weighted images are superior to other MR image types for the determination of diffuse intrinsic pontine glioma intratumoral heterogeneity

Harward, S., Harrison Farber, S., Malinzak, M., Becher, O. J. & Thompson, E. M., Mar 1 2018, In : Child's Nervous System. 34, 3, p. 449-455 7 p.

Research output: Contribution to journalArticle

Glioma
Convection
Corpus Callosum
Neoplasms
Catheters
2017
17 Citations (Scopus)

A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma

Kushner, B. H., Cheung, N. K. V., Modak, S., Becher, O. J., Basu, E. M., Roberts, S. S., Kramer, K. & Dunkel, I. J., Jan 15 2017, In : International Journal of Cancer. 140, 2, p. 480-484 5 p.

Research output: Contribution to journalArticle

Neuroblastoma
Disease-Free Survival
Salvage Therapy
perifosine
Survivors
14 Citations (Scopus)

A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors

Becher, O. J., Gilheeney, S. W., Khakoo, Y., Lyden, D. C., Haque, S., De Braganca, K. C., Kolesar, J. M., Huse, J. T., Modak, S., Wexler, L. H., Kramer, K., Spasojevic, I. & Dunkel, I. J., Jul 1 2017, In : Pediatric Blood and Cancer. 64, 7, e26409.

Research output: Contribution to journalArticle

Glioma
Pediatrics
Neoplasms
Medulloblastoma
Pharmacokinetics
7 Citations (Scopus)

A phase i study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors

Becher, O. J., Millard, N. E., Modak, S., Kushner, B. H., Haque, S., Spasojevic, I., Trippett, T. M., Gilheeney, S. W., Khakoo, Y., Lyden, D. C., De Braganca, K. C., Kolesar, J. M., Huse, J. T., Kramer, K., Cheung, N. K. V. & Dunkel, I. J., Jun 1 2017, In : PLoS One. 12, 6, e0178593.

Research output: Contribution to journalArticle

Pediatrics
Refractory materials
Tumors
neoplasms
Toxicity
30 Citations (Scopus)

Histone H3.3K27M represses p16 to accelerate gliomagenesis in a murine model of DIPG

Cordero, F. J., Huang, Z., Grenier, C., He, X., Hu, G., McLendon, R. E., Murphy, S. K., Hashizume, R. & Becher, O. J., Sep 1 2017, In : Molecular Cancer Research. 15, 9, p. 1243-1254 12 p.

Research output: Contribution to journalArticle

Glioma
Histones
Neoplasms
DNA Methylation
Mutation
74 Citations (Scopus)

Pediatric high-grade glioma: Biologically and clinically in need of new thinking

Jones, C., Karajannis, M. A., Jones, D. T. W., Kieran, M. W., Monje, M., Baker, S. J., Becher, O. J., Cho, Y. J., Gupta, N., Hawkins, C., Hargrave, D., Haas-Kogan, D. A., Jabado, N., Li, X. N., Mueller, S., Nicolaides, T., Packer, R. J., Persson, A. I., Phillips, J. J., Simonds, E. F. & 4 others, Stafford, J. M., Tang, Y., Pfister, S. M. & Weiss, W. A., Jan 1 2017, In : Neuro-oncology. 19, 2, p. 153-161 9 p.

Research output: Contribution to journalArticle

Glioma
Pediatrics
Glioblastoma
Chromatin
Neoplasms
35 Citations (Scopus)

Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models

Hennika, T., Hu, G., Olaciregui, N. G., Barton, K. L., Ehteda, A., Chitranjan, A., Chang, C., Gifford, A. J., Tsoli, M., Ziegler, D. S., Carcaboso, A. M. & Becher, O. J., Jan 1 2017, In : PloS one. 12, 1, e0169485.

Research output: Contribution to journalArticle

Heterografts
Glioma
clinical trials
Tumors
mice

Tumor-Specific Mutations in Gliomas and their Implications for Immunotherapy

Pirozzi, C. J., Carpenter, A. B., Hennika, T., Becher, O. J. & Yan, H., Mar 2 2017, Translational Immunotherapy of Brain Tumors. Sampson, J. (ed.). Elsevier Inc, p. 83-107 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Glioma
Immunotherapy
Mutation
Neoplasms
Isocitrate Dehydrogenase
3 Citations (Scopus)

Vamorolone, a dissociative steroidal compound, reduces pro-inflammatory cytokine expression in glioma cells and increases activity and survival in a murine model of cortical tumor

Wells, E., Kambhampati, M., Damsker, J. M., Gordish-Dressman, H., Yadavilli, S., Becher, O. J., Gittens, J., Stampar, M., Packer, R. J. & Nazarian, J., Jan 1 2017, In : Oncotarget. 8, 6, p. 9366-9374 9 p.

Research output: Contribution to journalArticle

Glioma
Dexamethasone
Cytokines
Survival
Neoplasms
2016
16 Citations (Scopus)

ABCG2 and ABCB1 limit the efficacy of dasatinib in a PDGF-B-driven brainstem glioma model

Mittapalli, R. K., Chung, A. H., Parrish, K. E., Crabtree, D., Halvorson, K. G., Hu, G., Elmquist, W. F. & Becher, O. J., May 2016, In : Molecular cancer therapeutics. 15, 5, p. 819-829 11 p.

Research output: Contribution to journalArticle

Glioma
Brain Stem
Knockout Mice
Blood-Brain Barrier
Brain Stem Neoplasms
14 Citations (Scopus)

A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells

Misuraca, K. L., Hu, G., Barton, K. L., Chung, A. & Becher, O. J., Jan 1 2016, In : Neoplasia. 18, 1, p. 60-70 11 p.

Research output: Contribution to journalArticle

Glioma
Brain Stem
Nestin
Pons
Mutation
11 Citations (Scopus)

Diffuse intrinsic pontine glioma: Time for cautious optimism

Hennika, T. & Becher, O. J., Oct 1 2016, In : Journal of child neurology. 31, 12, p. 1377-1385 9 p.

Research output: Contribution to journalArticle

Glioma
Biopsy
Hope
Mutation
Pons
1 Citation (Scopus)

Genetics of glioma

Hansen, L. J., Diplas, B. H., Becher, O. & Yan, H., Mar 31 2016, The Duke Glioma Handbook: Pathology, Diagnosis, and Management. Cambridge University Press, p. 1-23 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pediatric neuro-oncology: Time to go molecular

Becher, O. J., May 15 2016, In : ONCOLOGY (United States). 30, 5

Research output: Contribution to journalArticle

Pediatrics
Neoplasms
Staining and Labeling

Pediatric Neuro-Oncology: Time to Go Molecular

Becher, O. J., May 1 2016, In : Oncology (Williston Park, N.Y.). 30, 5, p. 424-425 2 p.

Research output: Contribution to journalComment/debate

Pediatrics
14 Citations (Scopus)

Tumor location, but not H3.3K27M, significantly influences the blood–brain-barrier permeability in a genetic mouse model of pediatric high-grade glioma

Subashi, E., Cordero, F. J., Halvorson, K. G., Qi, Y., Nouls, J. C., Becher, O. J. & Johnson, G. A., Jan 1 2016, In : Journal of Neuro-Oncology. 126, 2, p. 243-251 9 p.

Research output: Contribution to journalArticle

Genetic Models
Glioma
Permeability
Pediatrics
Brain Stem
2015
28 Citations (Scopus)

A high-throughput in Vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent

Halvorson, K. G., Barton, K. L., Schroeder, K., Misuraca, K. L., Hoeman, C., Chung, A., Crabtree, D. M., Cordero, F. J., Singh, R., Spasojevic, I., Berlow, N., Pal, R. & Becher, O. J., Mar 6 2015, In : PloS one. 10, 3, e0118926.

Research output: Contribution to journalArticle

Glioma
animal models
Throughput
drugs
therapeutics

Glioma Stem-like Cells Keep Their H3.3 Variant Levels at Bay

Becher, O. J. & Holland, E. C., Dec 14 2015, In : Cancer Cell. 28, 6, p. 679-680 2 p.

Research output: Contribution to journalShort survey

Chromatin Assembly and Disassembly
Neoplastic Stem Cells
DNA-Binding Proteins
Glioblastoma
Brain Neoplasms
6 Citations (Scopus)

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition

Shen, Y., Li, J., Nitta, M., Futalan, D., Steed, T., Treiber, J. M., Taich, Z., Stevens, D., Wykosky, J., Chen, H. Z., Carter, B. S., Becher, O. J., Kennedy, R., Esashi, F., Sarkaria, J. N., Furnari, F. B., Cavenee, W. K., Desai, A. & Chen, C. C., Jan 1 2015, In : Oncotarget. 6, 14, p. 11751-11767 17 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Clone Cells
Homologous Recombination
Therapeutic Uses
18 Citations (Scopus)

Pre-clinical models of diffuse intrinsic pontine glioma

Misuraca, K. L., Cordero, F. J. & Becher, O. J., Jan 1 2015, In : Frontiers in Oncology. 5, JUL, 172.

Research output: Contribution to journalReview article

Glioma
Heterografts
Brain Stem
Autopsy
Pons
12 Citations (Scopus)

The emerging role of NG2 in pediatric diffuse intrinsic pontine glioma

Yadavilli, S., Scafidi, J., Becher, O. J., Saratsis, A. M., Hiner, R. L., Kambhampati, M., Mariarita, S., MacDonald, T. J., Codispoti, K. E., Magge, S. N., Jaiswal, J. K., Packer, R. J. & Nazarian, J., Jan 1 2015, In : Oncotarget. 6, 14, p. 12141-12155 15 p.

Research output: Contribution to journalArticle

Glioma
Neuroglia
Pediatrics
Neurons
Antigens
2014
28 Citations (Scopus)

Children are not just little adults: Recent advances in understanding of diffuse intrinsic pontine glioma biology

Schroeder, K. M., Hoeman, C. M. & Becher, O. J., Jan 1 2014, In : Pediatric Research. 75, 1-2, p. 205-209 5 p.

Research output: Contribution to journalReview article

Glioma
Phosphatidylinositol 3-Kinase
Platelet-Derived Growth Factor Receptors
Mutation
Pons
7 Citations (Scopus)

For pediatric glioma, leave no histone unturned

Becher, O. J. & Wechsler-Reya, R. J., Dec 19 2014, In : Science. 346, 6216, p. 1458-1459 2 p.

Research output: Contribution to journalShort survey

Neoplastic Cell Transformation
Brain Stem Neoplasms
Neural Stem Cells
Genetic Models
Embryonic Stem Cells
259 Citations (Scopus)

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Buczkowicz, P., Hoeman, C., Rakopoulos, P., Pajovic, S., Letourneau, L., Dzamba, M., Morrison, A., Lewis, P., Bouffet, E., Bartels, U., Zuccaro, J., Agnihotri, S., Ryall, S., Barszczyk, M., Chornenkyy, Y., Bourgey, M., Bourque, G., Montpetit, A., Cordero, F., Castelo-Branco, P. & 32 others, Mangerel, J., Tabori, U., Ho, K. C., Huang, A., Taylor, K. R., Mackay, A., Bendel, A. E., Nazarian, J., Fangusaro, J. R., Karajannis, M. A., Zagzag, D., Foreman, N. K., Donson, A., Hegert, J. V., Smith, A., Chan, J., Lafay-Cousin, L., Dunn, S., Hukin, J., Dunham, C., Scheinemann, K., Michaud, J., Zelcer, S., Ramsay, D., Cain, J., Brennan, C., Souweidane, M. M., Jones, C., Allis, C. D., Brudno, M., Becher, O. & Hawkins, C., May 2014, In : Nature Genetics. 46, 5, p. 451-456 6 p.

Research output: Contribution to journalArticle

Glioma
Mutation
Brain Neoplasms
Histones
Activin Receptors
108 Citations (Scopus)

Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications

Buczkowicz, P., Bartels, U., Bouffet, E., Becher, O. & Hawkins, C., Jan 1 2014, In : Acta Neuropathologica. 128, 4, p. 573-581 9 p.

Research output: Contribution to journalArticle

Astrocytoma
Glioma
Pediatrics
Mutation
Therapeutics
266 Citations (Scopus)

Paediatric and adult glioblastoma: Multiform (epi)genomic culprits emerge

Sturm, D., Bender, S., Jones, D. T. W., Lichter, P., Grill, J., Becher, O., Hawkins, C., Majewski, J., Jones, C., Costello, J. F., Iavarone, A., Aldape, K., Brennan, C. W., Jabado, N. & Pfister, S. M., Feb 1 2014, In : Nature Reviews Cancer. 14, 2, p. 92-107 16 p.

Research output: Contribution to journalReview article

Glioblastoma
Pediatrics
Epigenomics
Glioma
Molecular Biology
14 Citations (Scopus)

Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma

Misuraca, K. L., Barton, K. L., Chung, A., Diaz, A. K., Conway, S. J., Corcoran, D. L., Baker, S. J. & Becher, O. J., Jan 27 2014, In : Acta Neuropathologica Communications. 2, 1, 134.

Research output: Contribution to journalArticle

Glioma
Brain Stem
Cerebral Cortex
Stem Cells
Apoptosis

Pediatric High-Grade Gliomas and DIPG

Becher, OJ., Barton, K., Halvorson, K. & McLendon, R., 2014, Molecular Pathology of Nervous System Tumors. Karajannis, M. & Zagzag, D. (eds.). New York: Springer New York, p. 95-104

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Citations (Scopus)

Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma

Becher, O. J. & Holland, E. C., Jan 1 2014, In : EMBO Journal. 33, 18, p. 1984-1986 3 p.

Research output: Contribution to journalArticle

Medulloblastoma
Neoplastic Stem Cells
Tumors
Squamous Cell Carcinoma
Skin
2013
20 Citations (Scopus)

Aurora kinase B is a potential therapeutic target in pediatric diffuse intrinsic pontine glioma

Buczkowicz, P., Zarghooni, M., Bartels, U., Morrison, A., Misuraca, K. L., Chan, T., Bouffet, E., Huang, A., Becher, O. & Hawkins, C., May 1 2013, In : Brain Pathology. 23, 3, p. 244-253 10 p.

Research output: Contribution to journalArticle

Aurora Kinase B
Astrocytoma
Glioma
Pediatrics
Therapeutics
534 Citations (Scopus)

Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

Lewis, P. W., Müller, M. M., Koletsky, M. S., Cordero, F., Lin, S., Banaszynski, L. A., Garcia, B. A., Muir, T. W., Becher, O. J. & Allis, C. D., May 17 2013, In : Science. 340, 6134, p. 857-861 5 p.

Research output: Contribution to journalArticle

Glioblastoma
Lysine
Pediatrics
Transgenes
Glioma
67 Citations (Scopus)

PD-0332991, a CDK4/6 Inhibitor, Significantly Prolongs Survival in a Genetically Engineered Mouse Model of Brainstem Glioma

Barton, K. L., Misuraca, K., Cordero, F., Dobrikova, E., Min, H. D., Gromeier, M., Kirsch, D. G. & Becher, O. J., Oct 2 2013, In : PloS one. 8, 10, e77639.

Research output: Contribution to journalArticle

brain stem
Glioma
Brain Stem
animal models
cyclins
2011
38 Citations (Scopus)

Disease control and ototoxicity using intensity-modulated radiation therapy tumor-bed boost for medulloblastoma

Polkinghorn, W. R., Dunkel, I. J., Souweidane, M. M., Khakoo, Y., Lyden, D. C., Gilheeney, S. W., Becher, O. J., Budnick, A. S. & Wolden, S. L., Nov 1 2011, In : International Journal of Radiation Oncology Biology Physics. 81, 3

Research output: Contribution to journalArticle

Medulloblastoma
acceleration (physics)
Craniospinal Irradiation
beds
radiation therapy
58 Citations (Scopus)

Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-Deficient PDGF-driven murine glioblastoma

Pitter, K. L., Galbán, C. J., Galbán, S., Saeed-Tehrani, O., Li, F., Charles, N., Bradbury, M. S., Becher, O. J., Chenevert, T. L., Rehemtulla, A., Ross, B. D., Holland, E. C. & Hambardzumyan, D., Feb 2 2011, In : PloS one. 6, 1, e14545.

Research output: Contribution to journalArticle

Cell death
Sirolimus
Glioblastoma
cell death
Cell Death
33 Citations (Scopus)

Reirradiation for recurrent medulloblastoma

Bakst, R. L., Dunkel, I. J., Gilheeney, S., Khakoo, Y., Becher, O., Souweidane, M. M. & Wolden, S. L., Nov 1 2011, In : Cancer. 117, 21, p. 4977-4982 6 p.

Research output: Contribution to journalArticle

Medulloblastoma
Radiation
Re-Irradiation
Recurrence
Retreatment
2010
6 Citations (Scopus)

Evidence for and against regional differences in neural stem and progenitor cells of the CNS

Becher, O. J. & Holland, E. C., Oct 15 2010, In : Genes and Development. 24, 20, p. 2233-2238 6 p.

Research output: Contribution to journalReview article

Neural Stem Cells
Stem Cells
Brain
Brain Neoplasms
Glioma
33 Citations (Scopus)

Heterozygosity for Ptenpromotes Tumorigenesis in a Mouse Model of Medulloblastoma

Castellino, R. C., Barwick, B. G., Schniederjan, M., Buss, M. C., Becher, O., Hambardzumyan, D., Macdonald, T. J., Brat, D. J. & Durden, D. L., Sep 17 2010, In : PloS one. 5, 5, e10849.

Research output: Contribution to journalArticle

Medulloblastoma
carcinogenesis
Tumors
heterozygosity
phosphatidylinositol 3-kinase
100 Citations (Scopus)

Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma

Becher, O. J., Hambardzumyan, D., Walker, T. R., Helmy, K., Nazarian, J., Albrecht, S., Hiner, R. L., Gall, S., Huse, J. T., Jabado, N., MacDonald, T. J. & Holland, E. C., Mar 15 2010, In : Cancer Research. 70, 6, p. 2548-2557 10 p.

Research output: Contribution to journalArticle

Glioma
Brain Stem
Radiation
Proto-Oncogene Proteins c-sis
Transferases
2009
8 Citations (Scopus)

Large congenital melanotic nevi in an extremity with neurocutaneous melanocytosis

Becher, O. J., Souweidane, M., Lavi, E., Kramer, K., Lis, E., Marghoob, A. A. & Khakoo, Y., Jan 1 2009, In : Pediatric Dermatology. 26, 1, p. 79-82 4 p.

Research output: Contribution to journalArticle

Nevus
Pigmented Nevus
Extremities
Spinal Puncture
Melanocytes
128 Citations (Scopus)

Modeling adult gliomas using RCAS/t-va technology

Hambardzumyan, D., Amankulor, N. M., Helmy, K. Y., Becher, O. J. & Holland, E. C., Jan 1 2009, In : Translational Oncology. 2, 2, p. 89-95 7 p.

Research output: Contribution to journalArticle

Glioma
Technology
Lateral Ventricles
Pediatrics
Central Nervous System Neoplasms
128 Citations (Scopus)

Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation

Amankulor, N. M., Hambardzumyan, D., Pyonteck, S. M., Becher, O. J., Joyce, J. A. & Holland, E. C., Aug 19 2009, In : Journal of Neuroscience. 29, 33, p. 10299-10308 10 p.

Research output: Contribution to journalArticle

Hedgehogs
Brain Injuries
Astrocytes
Gliosis
Inflammation
2008
90 Citations (Scopus)

Cancer stem cells and survival pathways

Hambardzumyan, D., Becher, O. J. & Holland, E. C., May 15 2008, In : Cell Cycle. 7, 10, p. 1371-1378 8 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Medulloblastoma
Cell Survival
Stem Cell Niche
Brain Neoplasms