Grants per year
Personal profile
Training Experience
| 1997 | Postdoctoral Fellowship, University of California, San Francisco |
| 2000 | Postdoctoral Fellowship, University of North Carolina |
Education/Academic qualification
Pharmaceutical Chemistry, PhD, University of California San Francisco
… → 1996
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Dive into the research topics where Pamela J Focia is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting Postsynaptic Small G-protein Regulators
Luan, C.-H. (PD/PI), Luan, C.-H. (PD/PI), Penzes, P. (PD/PI), Penzes, P. (PD/PI), Focia, P. J. (Co-Investigator), Parnell, E. L. (Co-Investigator), Parnell, E. L. (Co-Investigator), Schiltz, G. E. (Co-Investigator) & Schiltz, G. E. (Co-Investigator)
National Institute of Mental Health
7/19/22 → 6/30/26
Project: Research project
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RHLCCC: Structural Biology Facility
Focia, P. J. (Co-Investigator) & Mondragon, A. (Subproject PI)
8/1/16 → 7/31/18
Project: Research project
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The Robert H. Lurie Comprehensive Cancer Center
Platanias, L. C. (PD/PI), Larson, A. C. (Co-Investigator), Meade, T. J. (Co-Investigator), Ugolkov, A. (Co-Investigator), Awatramani, R. (Other), Backman, V. (Other), Benson III, A. B. (Other), Butt, Z. (Other), Carthew, R. W. (Other), Cella, D. (Other), Chakravarti, D. (Other), Crispino, J. D. (Other), Doglio, L. (Other), Eklund, E. A. (Other), Focia, P. J. (Other), Goolsby, C. L. (Other), Gordon, L. I. (Other), Green, K. J. (Other), Grigorescu, A. A. (Other), Hahn, E. A. (Other), Horvath, C. M. (Other), Jovanovic, B. (Other), Khan, S. A. (Other), Kiyokawa, H. (Other), Kuzel, T. M. (Other), LaBonne, C. (Other), Lai, J.-S. (Other), Li, L. (Other), Luan, C.-H. (Other), Mazar, A. P. (Other), Mondragon, A. (Other), O'Halloran, T. V. (Other), Penedo, F. J. (Other), Peter, M. E. (Other), Rademaker, A. W. (Other), Rosenzweig, A. C. (Other), Scheidt, K. A. (Other), Scholtens, D. M. (Other), Spring, B. (Other), Tourtellotte, W. (Other), Weiss, E. L. (Other) & Woloschak, G. E. (Other)
9/16/13 → 7/31/16
Project: Research project
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RHLCCC: Structural Biology Facility
Mondragon, A. (PD/PI), Focia, P. J. (Co-PD/PI), Mondragon, A. (Co-PD/PI) & Mondragon, A. (Other)
9/16/13 → 7/31/16
Project: Research project
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Structural Studies on Prokaryotic Potassium Channels
Focia, P. J. (Co-Investigator)
National Institute of General Medical Sciences
12/1/10 → 7/31/11
Project: Research project
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A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation
Watari, H., Kageyama, H., Masubuchi, N., Nakajima, H., Onodera, K., Focia, P. J., Oshiro, T., Matsui, T., Kodera, Y., Ogawa, T., Yokoyama, T., Hirayama, M., Hori, K., Freymann, D. M., Imai, M., Komatsu, N., Araki, M., Tanaka, Y. & Sakai, R., Dec 2022, In: Nature communications. 13, 1, 7262.Research output: Contribution to journal › Article › peer-review
Open Access -
DNA-Directed Protein Packing within Single Crystals
Winegar, P. H., Hayes, O. G., McMillan, J. R., Figg, C. A., Focia, P. J. & Mirkin, C. A., Apr 9 2020, In: Chem. 6, 4, p. 1007-1017 11 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase
Smith, K. P., Focia, P. J., Chakravarthy, S., Landahl, E. C., Klosowiak, J. L., Rice, S. E. & Freymann, D. M., Dec 1 2020, In: Journal of Structural Biology. 212, 3, 107656.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Structural insights into Parkin substrate lysine targeting from minimal Miro substrates
Klosowiak, J. L., Park, S., Smith, K. P., French, M. E., Focia, P. J., Freymann, D. M. & Rice, S. E., Sep 8 2016, In: Scientific reports. 6, 33019.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Structures of KcsA in complex with symmetrical quaternary ammonium compounds reveal a hydrophobic binding site
Lenaeus, M. J., Burdette, D., Wagner, T., Focia, P. J. & Gross, A., Aug 19 2014, In: Biochemistry. 53, 32, p. 5365-5373 9 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations
Datasets
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5KUT : hMiro2 C-terminal GTPase domain, GDP-bound
Klosowiak, J. L. (Contributor), Focia, P. J. (Contributor), Freymann, D. M. (Contributor) & Rice, S. E. (Contributor), RCSB-PDB, 2016
DOI: 10.2210/pdb5kut/pdb, https://www.rcsb.org/structure/5KUT
Dataset
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4C0L : Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one magnesium ion and Mg:GDP (MgGDP-MiroS)
Klosowiak, J. L. (Contributor), Focia, P. J. (Contributor), Freymann, D. M. (Contributor), Rice, S. E. (Contributor), Chakravarthy, S. (Contributor) & Landahl, E. C. (Contributor), RCSB-PDB, 2013
DOI: 10.2210/pdb4c0l/pdb, https://www.rcsb.org/structure/4C0L
Dataset
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1I0L : ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ASPARAGINE MUTANT
Canyuk, B. (Contributor), Focia, P. J. (Contributor) & Eakin, A. E. (Contributor), RCSB-PDB, 2002
DOI: 10.2210/pdb1i0l/pdb, https://www.rcsb.org/structure/1I0L
Dataset
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2BOC : Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs)
Lenaeus, M. J. (Contributor), Vamvouka, M. (Contributor), Focia, P. J. (Contributor) & Gross, A. (Contributor), RCSB-PDB, 2005
DOI: 10.2210/pdb2boc/pdb, https://www.rcsb.org/structure/2BOC
Dataset
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1OKK : HOMO-HETERODIMERIC COMPLEX OF THE SRP GTPASES
Focia, P. J. (Contributor) & Freymann, D. M. (Contributor), RCSB-PDB, 2004
DOI: 10.2210/pdb1okk/pdb, https://www.rcsb.org/structure/1OKK
Dataset